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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Septasteril Sachet 5 gm is used to treat chronic kidney disease. It contains Alpha Ketoanalogue, which works by lowering urea levels in the blood and improving kidney function. In some cases, this medicine may cause side effects such as increased calcium levels, nausea, vomiting, diarrhoea, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Drug-Drug Interactions

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TryptophanSafinamide
Critical
TryptophanTranylcypromine
Critical

Drug-Drug Interactions

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TryptophanSafinamide
Critical
How does the drug interact with Septasteril Sachet 5 gm:
Taking Safinamide with Septasteril Sachet 5 gm can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Septasteril Sachet 5 gm is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TryptophanTranylcypromine
Critical
How does the drug interact with Septasteril Sachet 5 gm:
Taking tranylcypromine with Septasteril Sachet 5 gm can increase the risk of serotonin syndrome ( high levels of serotonin in body which result in shivering, high fever, diarrhea & muscle stiffness) .

How to manage the interaction:
Taking Tranylcypromine with Septasteril Sachet 5 gm is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanAmitriptyline
Severe
How does the drug interact with Septasteril Sachet 5 gm:
Combining Septasteril Sachet 5 gm with Amitriptyline can increase the risk of serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although using Septasteril Sachet 5 gm and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
TryptophanParoxetine
Severe
How does the drug interact with Septasteril Sachet 5 gm:
Coadministration of Paroxetine with Septasteril Sachet 5 gm can increase the side effects of paroxetine.

How to manage the interaction:
Although there is a possible interaction between Paroxetine and Septasteril Sachet 5 gm, you can take these medicines together if prescribed by your doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TryptophanPentazocine
Severe
How does the drug interact with Septasteril Sachet 5 gm:
Coadministration of Pentazocine with Septasteril Sachet 5 gm may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Pentazocine and Septasteril Sachet 5 gm, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanSumatriptan
Severe
How does the drug interact with Septasteril Sachet 5 gm:
Using Septasteril Sachet 5 gm together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction between Sumatriptan and Septasteril Sachet 5 gm, you can take these medicines together if prescribed by your doctor. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
TryptophanBuspirone
Severe
How does the drug interact with Septasteril Sachet 5 gm:
Using Buspirone together with Septasteril Sachet 5 gm can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Although there is a possible interaction between Buspirone and Septasteril Sachet 5 gm, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on your health and be aware of any changes. If you notice any of these symptoms like confusion, increased heart rate, or stomach cramps, it's a good idea to reach out to a doctor right away. They can help determine the cause and provide the necessary treatment. Do not stop using any medications without a doctor's advice.
TryptophanClomipramine
Severe
How does the drug interact with Septasteril Sachet 5 gm:
The combined use of Septasteril Sachet 5 gm with clomipramine can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Although taking clomipramine and Septasteril Sachet 5 gm together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.
TryptophanDesvenlafaxine
Severe
How does the drug interact with Septasteril Sachet 5 gm:
Co-administration of Septasteril Sachet 5 gm and Desvenlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Septasteril Sachet 5 gm and Desvenlafaxine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TryptophanDoxepin
Severe
How does the drug interact with Septasteril Sachet 5 gm:
The combined use of Septasteril Sachet 5 gm and Doxepin can increase the risk of serotonin syndrome(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Septasteril Sachet 5 gm and Doxepin can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, diarrhoea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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