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निर्माता/विपणक :
ज़ुवेंटस हेल्थकेयर लिमिटेड
सेवन का प्रकार :
मौखिक
वापसी नीति :
3 दिन वापसी योग्य
इसके बाद या इसके बाद समाप्त होता है :
Jan-27
Health Queries
I am using tolkem d since from 25/10/25, about one month,
Dr Bayyarapu Kumar
M Pharmacy
Tolkem D, which contains diclofenac and tolperisone, is intended for short-term relief of pain and muscle spasm and should not be taken for long periods without a doctor’s supervision, as prolonged use can cause side effects and will not treat the underlying slipped disc. If you have already used it for about one month and still have pain in your hands and legs, it suggests that the slipped disc needs further medical evaluation rather than continuing the same medicine. Your doctor can assess the severity, adjust your treatment, and guide you on safer long-term options such as physiotherapy, posture correction, exercises, or alternative medicines.
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Drug-Drug Interactions
Critical
Severe
Drug-Drug Interactions
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Critical
How does the drug interact with Tolkem D Tablet:
Co-administration of Tolkem D Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.
How to manage the interaction:
Taking Meloxicam with Tolkem D Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
Co-administration of Tolkem D Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.
How to manage the interaction:
Taking Meloxicam with Tolkem D Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
Severe
How does the drug interact with Tolkem D Tablet:
Taking Tolkem D Tablet with Enoxaparin can increase the risk of bleeding complications.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
Taking Tolkem D Tablet with Enoxaparin can increase the risk of bleeding complications.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tolkem D Tablet:
Taking Tolkem D Tablet with human immunoglobulin may increase the risk of kidney problems.
How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Tolkem D Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Taking Tolkem D Tablet with human immunoglobulin may increase the risk of kidney problems.
How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Tolkem D Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tolkem D Tablet:
Coadministration of Tolkem D Tablet with fondaparinux may increase the risk of bleeding.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Coadministration of Tolkem D Tablet with fondaparinux may increase the risk of bleeding.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Tolkem D Tablet:
Taking Tolkem D Tablet with Ibrutinib can increase the risk of bleeding tendencies.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
Taking Tolkem D Tablet with Ibrutinib can increase the risk of bleeding tendencies.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tolkem D Tablet:
Co-administration of Tolkem D Tablet and Apixaban may raise the risk of stomach bleeding.
How to manage the interaction:
Although there is a interaction between Tolkem D Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
Co-administration of Tolkem D Tablet and Apixaban may raise the risk of stomach bleeding.
How to manage the interaction:
Although there is a interaction between Tolkem D Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
Severe
How does the drug interact with Tolkem D Tablet:
Taking Dasatinib together with Tolkem D Tablet may increase the risk of bleeding.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
Taking Dasatinib together with Tolkem D Tablet may increase the risk of bleeding.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tolkem D Tablet:
Coadministration of Tolkem D Tablet with Ketoconazole may increase the risk of liver problems.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Coadministration of Tolkem D Tablet with Ketoconazole may increase the risk of liver problems.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tolkem D Tablet:
Concomitant administration of Tolkem D Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
Concomitant administration of Tolkem D Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.
How to manage the interaction:
There may be a possible interaction between Tolkem D Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacMipomersen
Severe
How does the drug interact with Tolkem D Tablet:
Co-administration of Tolkem D Tablet with Mipomersen may cause liver problems.
How to manage the interaction:
Co-administration of Tolkem D Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Co-administration of Tolkem D Tablet with Mipomersen may cause liver problems.
How to manage the interaction:
Co-administration of Tolkem D Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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शराब
असुरक्षित
टोलकेम डी टैबलेट 10 लेते समय शराब के सेवन से बचें क्योंकि इससे चक्कर आना बढ़ सकता है। यह पेट से खून बहने का खतरा भी बढ़ा सकता है।
गर्भावस्था
सावधानी
यदि आप गर्भवती हैं तो टोलकेम डी टैबलेट 10 लेने से बचें जब तक कि डॉक्टर द्वारा निर्धारित न किया गया हो। यदि आपको इसे लेकर कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें, आपका डॉक्टर तभी लिखेगा जब लाभ जोखिमों से अधिक होगा।
स्तनपान
असुरक्षित
स्तनपान के दौरान टोलकेम डी टैबलेट 10 का उपयोग नहीं करना चाहिए।
ड्राइविंग
सावधानी
टोलकेम डी टैबलेट 10 से नींद आना या चक्कर आना हो सकता है। जब तक आप यह न जान लें कि यह आपको कैसे प्रभावित करता है, तब तक गाड़ी न चलाएं या ऐसा कुछ भी न करें जिसमें एकाग्रता की आवश्यकता हो।
जिगर
असुरक्षित
जिन लोगों को लीवर की गंभीर समस्या है, उन्हें यह टोलकेम डी टैबलेट 10 नहीं लेना चाहिए क्योंकि टोलकेम डी टैबलेट 10 में टॉलपरिसोन होता है, जो लीवर की बीमारी वाले रोगियों में सबसे खतरनाक प्रतिकूल प्रभाव डालता है।
गुर्दा
असुरक्षित
जिन लोगों को किडनी की गंभीर समस्या है, उन्हें यह टोलकेम डी टैबलेट 10 नहीं लेना चाहिए क्योंकि टोलकेम डी टैबलेट 10 में टॉलपरिसोन होता है, जो किडनी की बीमारी वाले रोगियों में सबसे खतरनाक प्रतिकूल प्रभाव डालता है।
बच्चे
असुरक्षित
बच्चों को टोलकेम डी टैबलेट 10 नहीं देना चाहिए क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई थी।
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