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Jan-27
Drug-Drug Interactions
Critical
Severe
Drug-Drug Interactions
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Critical
How does the drug interact with Problast Capsule:
Coadministration of Problast Capsule with Eltrombopag can impair the absorption of Eltrombopag which leads to increased levels in the blood. This can increase the risk and severity of side effects.
How to manage the interaction:
Taking Problast Capsule with Eltrombopag together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Problast Capsule with Eltrombopag can impair the absorption of Eltrombopag which leads to increased levels in the blood. This can increase the risk and severity of side effects.
How to manage the interaction:
Taking Problast Capsule with Eltrombopag together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Problast Capsule:
Coadministration of Problast Capsule with Gefitinib impairs absorption and increases the Gefitinib levels in the body. This may increase the risk or severity of side effects.
How to manage the interaction:
Taking Problast Capsule with Gefitinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any Blistering, peeling or loosening of the skin, bloody, black, or tarry stools, eye redness or pain, heartburn, indigestion, joint or muscle pain, or abdomen pain you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Problast Capsule with Gefitinib impairs absorption and increases the Gefitinib levels in the body. This may increase the risk or severity of side effects.
How to manage the interaction:
Taking Problast Capsule with Gefitinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any Blistering, peeling or loosening of the skin, bloody, black, or tarry stools, eye redness or pain, heartburn, indigestion, joint or muscle pain, or abdomen pain you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Problast Capsule:
Taking dolutegravir with Problast Capsule can reduce the effectiveness of dolutegravir.
How to manage the interaction:
Taking Problast Capsule with Dolutegravir together can result in an interaction, it can be taken if your doctor has advised it. However, take dolutegravir at least two hours before or six hours after the Problast Capsule dose. Do not stop using any medications without talking to a doctor.
Taking dolutegravir with Problast Capsule can reduce the effectiveness of dolutegravir.
How to manage the interaction:
Taking Problast Capsule with Dolutegravir together can result in an interaction, it can be taken if your doctor has advised it. However, take dolutegravir at least two hours before or six hours after the Problast Capsule dose. Do not stop using any medications without talking to a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.
How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
Co-administration of Problast Capsule with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.
How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Problast Capsule:
Co-administration of Isoniazid with Problast Capsule may decrease the effects of Problast Capsule.
How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
Co-administration of Isoniazid with Problast Capsule may decrease the effects of Problast Capsule.
How to manage the interaction:
Although there is an interaction, Problast Capsule can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
CalcitriolAmobarbital
Severe
How does the drug interact with Problast Capsule:
Co-administration of Amobarbital and Problast Capsule may decrease the effects of Problast Capsule.
How to manage the interaction:
Co-administration of Problast Capsule with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Amobarbital and Problast Capsule may decrease the effects of Problast Capsule.
How to manage the interaction:
Co-administration of Problast Capsule with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Problast Capsule:
Co-administration of Cholecalciferol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between colecalciferol and Problast Capsule, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Cholecalciferol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.
How to manage the interaction:
Although there is a possible interaction between colecalciferol and Problast Capsule, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Problast Capsule:
Co-administration of Doxercalciferol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.
How to manage the interaction:
Taking Doxercalciferol with Problast Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
Co-administration of Doxercalciferol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.
How to manage the interaction:
Taking Doxercalciferol with Problast Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolErgocalciferol
Severe
How does the drug interact with Problast Capsule:
Co-administration of Ergocalciferol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.
How to manage the interaction:
Co-administration of Ergocalciferol with Problast Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
Co-administration of Ergocalciferol and Problast Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.
How to manage the interaction:
Co-administration of Ergocalciferol with Problast Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Problast Capsule:
Co-administration of Problast Capsule with Dihydrotachysterol can increase the risk of adverse effects.
How to manage the interaction:
Co-administration of Dihydrotachysterol with Problast Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Problast Capsule with Dihydrotachysterol can increase the risk of adverse effects.
How to manage the interaction:
Co-administration of Dihydrotachysterol with Problast Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Product Substitutes
शराब
Caution
शराब पीने से कैल्शियम अवशोषण प्रभावित हो सकता है; इसलिए प्रोब्लास्ट कैप्सूल 10's का उपयोग करते समय शराब का सेवन सीमित करने की सलाह दी जाती है।
गर्भावस्था
Caution
गर्भावस्था के दौरान, डॉक्टर की सलाह पर ही दैनिक आहार भत्ते से अधिक खुराक का उपयोग करें। अधिक खुराक में कैल्सीट्रियोल भ्रूण को नुकसान पहुंचा सकता है। आपका डॉक्टर प्रोब्लास्ट कैप्सूल 10's की सिफारिश करने से पहले संभावित जोखिमों और लाभों का मूल्यांकन करेगा।
स्तनपान
Caution
यदि आप स्तनपान करा रही हैं तो प्रोब्लास्ट कैप्सूल 10's लेने से पहले अपने डॉक्टर से सलाह लें। प्रोब्लास्ट कैप्सूल 10's स्तन के दूध में जा सकता है। यदि प्रोब्लास्ट कैप्सूल 10's का उपयोग स्तनपान के दौरान किया जाता है, तो कृपया माँ और शिशु के सीरम कैल्शियम के स्तर की निगरानी करें।
ड्राइविंग
Caution
कोई अंतःक्रिया नहीं पाई गई/स्थापित नहीं हुई।
जिगर
Caution
अगर आपको लिवर की बीमारियों का कोई इतिहास है तो प्रोब्लास्ट कैप्सूल 10's लेने से पहले अपने डॉक्टर को बताएँ। हेपेटिक दुर्बलता/लिवर रोग कुछ विटामिन डी रूपों की चयापचय और चिकित्सीय गतिविधि को बदल सकता है।
किडनी
Caution
यदि आपको गुर्दे की पथरी जैसी किडनी की बीमारी है या आप डायलिसिस करवा रहे हैं तो प्रोब्लास्ट कैप्सूल 10's शुरू करने से पहले डॉक्टर की सलाह लेने की सलाह दी जाती है। प्रोब्लास्ट कैप्सूल 10's में मौजूद कैल्सीट्रियोल सीरम में अकार्बनिक फॉस्फेट के स्तर को बढ़ाता है; इसलिए डायलिसिस करवाने वाले मरीजों को पर्याप्त फॉस्फोरस के स्तर को बनाए रखने और एक्टोपिक कैल्सीफिकेशन (कैल्शियम जमाव) से बचने के लिए सावधानी बरतनी चाहिए।
बच्चे
Caution
प्रोब्लास्ट कैप्सूल 10's का प्रयोग बच्चों में सावधानी के साथ किया जाना चाहिए तथा केवल तभी किया जाना चाहिए जब डॉक्टर द्वारा इसकी सिफारिश की गई हो।
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