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Grafnos 0.5 Capsule Substitute

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Verified Ingredients and Effects

Composition:

TACROLIMUS-0.5MG

Uses:

<p>Grafnos 0.5 Capsule is used to treat various medical conditions. The detailed uses are as follows:</p><ul><li><strong>Prevention of Organ Transplant Rejection:</strong> Grafnos 0.5 Capsule is used to stop the body from rejecting a transplanted kidney, liver, heart, or lung. It works by lowering the activity of certain immune cells that could attack the new organ. It is usually given along with other anti-rejection medicines.</li><li><strong>Other Off-Label Uses:</strong> In some cases, Grafnos 0.5 Capsule may be used for graft-versus-host disease (after bone marrow or stem cell transplant), autoimmune liver diseases (autoimmune hepatitis, lupus nephritis), autoimmune eye conditions (uveitis, scleritis), and other immune-related disorders such as rheumatoid arthritis, Crohn’s disease, or myasthenia gravis, particularly when standard treatments are not effective.</li></ul>

Medicinal Benefits:

  • Grafnos 0.5 Capsule belongs to the class of medicines called immunosuppressants, which reduce the activity of the body's immune system, and it contains Tacrolimus as the active ingredient.
  • It works by lowering the activity of certain white blood cells (T-lymphocytes) that trigger immune reactions, helping to prevent the body from attacking transplanted organs and reducing harmful immune responses.
  • It is used to prevent rejection of kidney, liver, heart, or lung transplants, usually along with other anti-rejection medicines.
  • It may also be used for graft-versus-host disease, autoimmune liver conditions, autoimmune eye inflammation, and certain severe autoimmune diseases (such as rheumatoid arthritis, Crohn's disease, or myasthenia gravis) when other treatments are not effective.
  • It provides several benefits, including protecting transplanted organs from rejection, improving long-term transplant survival, reducing the need for high-dose steroids, managing severe immune reactions in certain diseases, and improving quality of life for transplant patients.

FAQs

Grafnos 0.5 Capsule is used to prevent rejection of a transplanted organ, such as a liver, kidney, or heart.

Grafnos 0.5 Capsule contains Tacrolimus, an immunosuppressant that works by inhibiting the activity of T and B lymphocytes (cells in the immune system) that usually attack foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Grafnos 0.5 Capsule may increase the risk of infections as it may weaken the immune system. Therefore, consult a doctor immediately if you have any signs of infection, such as a sore throat or fever.

Grafnos 0.5 Capsule may increase the risk of skin cancer. Therefore, avoid or limit exposure to the sun for extended periods or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella (MMR), oral polio, varicella, yellow fever, intranasal influenza, BCG and TY21a typhoid vaccines, inform your doctor that you are taking Grafnos 0.5 Capsule because it may reduce the effectiveness of the vaccine and increase your risk of contracting the infection that the vaccine is meant to protect against.

Using Grafnos 0.5 Capsule with Sirolimus is not recommended in patients who have had heart or liver transplants. It is unknown if kidney transplant recipients can use it safely. Hence, please seek medical advice before combining Grafnos 0.5 Capsule with other medications.

Grafnos 0.5 Capsule may cause tremors, trembling and shaking of hands. Consult the doctor if this becomes bothersome.

Grafnos 0.5 Capsule is usually taken on an empty stomach or 2 to 3 hours after a meal. Wait at least 1 hour until the next meal.

Grafnos 0.5 Capsule is a macrolide antibiotic with immunosuppressant properties.

Grafnos 0.5 Capsule should not be taken by people who are allergic to any of its components, allergic to sirolimus or any macrolide-antibiotic, during breastfeeding, and receiving live vaccines.

Let the doctor know if you have long QT syndrome, low or high levels of potassium, low levels of calcium or magnesium, an irregular heartbeat, high blood pressure, high cholesterol levels, cystic fibrosis (an inborn disease), heart, kidney, or liver disease. Inform the doctor if you have a weak immune system or if you are due to undergo any vaccination.

Grafnos 0.5 Capsule decreases the activity of your immune system, increasing the risk of serious infection and cancer (lymphoma cancer). Consult the doctor if you experience symptoms of infection (sore throat, extreme tiredness, cough, flu-like symptoms, fever,) or cancer (weight loss, swollen lymph nodes in the neck, armpits, or groin, fever, excessive tiredness or weakness, night sweats, cough, chest pain, trouble breathing, or pain, swelling, or fullness in the stomach area).

No, Grafnos 0.5 Capsule does not have an abuse potential as it is not a controlled substance.

Side effects of Grafnos 0.5 Capsule include nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. If the side effects persist or worsen, please consult your doctor.