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2-Flo-Nerv Injection 2 ml is used to treat nutritional deficiencies and as adjuvant therapy for various medical conditions. It contains methylcobalamin (vitamin B12), niacinamide (nicotinamide), and pyridoxine (vitamin B6). Together, they provide essential nutrients for adequate growth and proper organ functioning. 2-Flo-Nerv Injection 2 ml may cause side effects such as upset stomach, constipation, diarrhoea, nausea, and injection site reactions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METHYLCOBALAMIN-1500MCG+NIACINAMIDE-100MG+PYRIDOXINE-100MG

Manufacturer/Marketer :

Henry Pharmaceuticals

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About 2-Flo-Nerv Injection 2 ml

2-Flo-Nerv Injection 2 ml is an injectable prescription medicine used to treat peripheral neuropathy and clinical conditions caused by vitamin B6, vitamin B12, and niacin deficiencies. It is especially useful when oral therapy is not feasible, such as in critically ill patients, ICU patients, or people with excessive vomiting. By delivering these vitamins directly into the body, it helps restore depleted nutrient levels more quickly. 

To achieve the best results, you should receive 2-Flo-Nerv Injection 2 ml exactly as prescribed by your doctor. In severe cases, it may be given daily until symptoms improve and then reduced to maintenance dosing. Because it is administered by injection, food does not affect how it works. This medicine is intended for adult use and is for single use only. 

While using this injection, some people may experience mild side effects such as pain or redness at the injection site, nausea, vomiting, diarrhoea, dizziness, headache, or flushing. Seek medical attention immediately if you develop difficulty breathing, facial swelling, severe rash, or other signs of a serious allergic reaction. Long-term high-dose pyridoxine exposure can also cause peripheral sensory neuropathy, so new tingling or numbness should be reported promptly. 

Do not use this medicine if you are allergic to any of its ingredients. Tell your doctor before treatment if you have hypertension, cardiovascular disease, lung disease, diabetes, liver disease, or a history of bleeding-related problems, because extra caution may be needed in these settings. 

This medicine can interact with several drugs, including metformin, phenytoin, phenobarbital, isoniazid, hydralazine, penicillamine, oral contraceptives, levodopa, carbamazepine, diazepam, and sodium valproate. If you are pregnant, breastfeeding, or an older adult, consult your doctor before starting treatment. Large doses of nicotinamide should be avoided in pregnancy, and caution is advised in nursing mothers.

Uses of 2-Flo-Nerv Injection 2 ml

Your doctor may prescribe 2-Flo-Nerv Injection 2 ml to treat the following conditions:

  • Peripheral neuropathy: Helps relieve nerve pain, tingling, numbness, and burning sensations in the hands and feet.
  • Clinical conditions resulting in B6, B12, or niacin deficiencies: Used when these deficiencies need parenteral correction, especially when oral therapy is not feasible.

Key Benefits

By bypassing the digestive tract, 2-Flo-Nerv Injection 2 ml provides rapid delivery of essential vitamins, which is helpful when absorption is poor or oral treatment cannot be used. This supports faster correction of deficiency states and helps the body recover more reliably than oral supplements in selected patients. 

  • Supports nerve health: Methylcobalamin helps with myelin-related processes and nerve repair, while pyridoxine supports neurotransmitter and amino-acid metabolism.
  • Helps reduce neuropathic symptoms: May help ease numbness, tingling, and burning pain associated with peripheral neuropathy.
  • Supports energy metabolism: Niacinamide helps form NAD, which is important for cellular energy production and neuronal function.
  • Corrects deficiency states: Replenishes depleted B-vitamin stores when dietary intake or oral absorption is inadequate.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication, to improve effectiveness.
  • 2-Flo-Nerv Injection 2 ml will be administered by a healthcare professional.
  • Do not self-administer it.

How 2-Flo-Nerv Injection 2 ml Works

2-Flo-Nerv Injection 2 ml combines three essential vitamins that work together to support nervous system and metabolic health. Methylcobalamin supports methylation reactions involved in myelin formation and nerve regeneration. Pyridoxine is converted in the body to pyridoxal 5’-phosphate, an active coenzyme required for amino-acid, neurotransmitter, and haem-related metabolism. Niacinamide contributes to NAD/NADH production, which is important for cellular energy and neuronal maintenance. Together, these nutrients help restore depleted stores, support nerve repair, and improve metabolic function in patients with deficiency-related symptoms.
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Alcohol

Caution

No interaction was found. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

Limited data are available on the effect of 2-Flo-Nerv Injection 2 ml in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving 2-Flo-Nerv Injection 2 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data are available on the effect of 2-Flo-Nerv Injection 2 ml on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving 2-Flo-Nerv Injection 2 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Safe

2-Flo-Nerv Injection 2 ml does not impact your ability to drive or use machinery.

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Liver

Caution

Inform your doctor if you have had any history of liver diseases before taking 2-Flo-Nerv Injection 2 ml. Your doctor will weigh the benefits and potential risks before prescribing 2-Flo-Nerv Injection 2 ml.

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Kidney

Caution

Inform your doctor if you have had any history of kidney diseases before taking 2-Flo-Nerv Injection 2 ml. Your doctor will weigh the benefits and potential risks before prescribing 2-Flo-Nerv Injection 2 ml.

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Children

Unsafe

There was limited information about the usage of 2-Flo-Nerv Injection 2 ml in paediatric patients. Please seek medical advice. Only if the benefits exceed the dangers will your doctor prescribe.

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Heart

Caution

2-Flo-Nerv Injection 2 ml is generally safe for heart patients and supports nerve and metabolic health. However, it's important to consult your doctor to avoid any interaction with cardiac medications.

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Geriatrics

Caution

Geriatric patients can receive 2-Flo-Nerv Injection 2 ml, as it's generally safe and supports nerve and metabolic health. However, age-related organ changes may increase sensitivity, so medical supervision is important.

What if I have taken an overdose of 2-Flo-Nerv Injection 2 ml

An overdose is unlikely when the medicine is administered by a healthcare professional. However, excessive pyridoxine exposure over time can cause sensory neuropathy, and very high nicotinamide doses may cause adverse effects such as nausea, vomiting, or liver-related problems. Seek medical attention if an overdose is suspected or if severe symptoms develop.

Diet & Lifestyle Advise

  • Eat a balanced diet: Include B-vitamin-rich foods such as lean meats, fish, eggs, dairy, whole grains, and leafy green vegetables to support recovery.
  • Limit alcohol intake: Excessive alcohol can worsen vitamin deficiency states and should be avoided or strictly limited.
  • Quit smoking: Smoking can hinder recovery and worsen overall vascular and nerve health.
  • Stay hydrated: Drink enough water each day to support general health while receiving parenteral vitamin therapy.
  • Keep follow-up appointments: Routine monitoring helps your doctor assess treatment response and adjust dosing if needed.
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Have a query?

How Soon It Starts Working

The time required for 2-Flo-Nerv Injection 2 ml to start to work: 2-Flo-Nerv Injection 2 ml ideally shows its action within 2 hours after administration. The time for which the effects of 2-Flo-Nerv Injection 2 ml last: The duration of action for 2-Flo-Nerv Injection 2 ml is unknown.

What if you forget to take 2-Flo-Nerv Injection 2 ml

If you miss an appointment for your injection, contact your doctor or clinic as soon as possible to reschedule. Do not inject a double dose to make up for a missed one.

Storage

• Store 2-Flo-Nerv Injection 2 ml at or below 30°C and protect it from light. Keep the ampoule in its original carton, and do not freeze the medicine.

Drug Warnings

  • Inspect the vial before use: Do not use the injection if the liquid is cloudy, discoloured, or contains visible particles.
  • Use only once: The ampoule is for single use only and should be discarded after opening.
  • Rotate injection sites: If injections are given regularly, changing the site can help reduce pain and local irritation.
  • Watch for allergic signs: Seek help promptly if you develop itching, rash, facial swelling, or breathing changes after an injection.
  • Keep up with routine blood tests: Your doctor may monitor your vitamin status and related labs to confirm the treatment is working.

verifiedApollotooltip
  • Metformin: Long-term use may be associated with reduced vitamin B12 levels, so monitoring may be needed.
  • Phenytoin and phenobarbital: Serum concentrations have been reported to decrease with concomitant use of mecobalamin.
  • Isoniazid, hydralazine, penicillamine, and oral contraceptives: May increase pyridoxine requirements.
  • Levodopa: Pyridoxine can reduce its effect unless used with an appropriate decarboxylase inhibitor.
  • Carbamazepine, diazepam, and sodium valproate: Niacinamide may potentiate anticonvulsant action and may decrease carbamazepine clearance.

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  • Alcohol: No direct food interaction is established, but heavy alcohol use can worsen deficiency states and reduce treatment effectiveness.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[VITAMINS]

FAQs

The frequency of 2-Flo-Nerv Injection 2 ml injections depends on your nutritional deficiency, medical condition, and your doctor's treatment plan. Your doctor will determine the appropriate dose and schedule, which may vary from person to person. Do not take or receive 2-Flo-Nerv Injection 2 ml more frequently than prescribed.
Many patients begin to feel an increase in energy levels within a few days, but nerve healing is a gradual process. It may take several weeks of consistent treatment to notice a significant reduction in nerve pain or numbness. Talk to your doctor if you do not notice any improvement after a few weeks.
Yes, this medicine generally does not affect your ability to drive. However, if you experience temporary dizziness or lightheadedness immediately after the injection, wait until you feel fully alert before driving. Talk to your doctor if these symptoms persist.
While the nutrients in this injection are essential, high-dose parenteral vitamins should only be used during pregnancy if clearly needed and prescribed by your obstetrician. Talk to your doctor to determine if this treatment is safe for you and your baby.
An injection delivers the nutrients directly into your bloodstream, completely bypassing the digestive tract. This is highly beneficial for people who have gut absorption issues, severe deficiencies, or conditions that make swallowing oral pills difficult. Talk to your doctor about which form is best for your health needs.
It is highly recommended to avoid or limit alcohol while using this medicine. Alcohol impairs your body’s ability to absorb and utilize these essential nutrients, which can make the treatment much less effective. Talk to your doctor for advice on safe alcohol consumption.
Mild pain, redness, or swelling at the injection site is common and usually goes away within a few hours. Applying a cold compress to the area can help relieve discomfort. Talk to your doctor if the pain worsens, or if you notice signs of infection like pus or warmth around the site.
This medicine is not known to cause weight gain directly. However, as it helps restore your energy levels and normal metabolic function, your appetite may improve, which could lead to healthy weight maintenance if you were previously underweight due to illness. Talk to your doctor if you have concerns about weight changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Devkinandan Basement , Tekdi, Ulhasnagar 1, Mumbai Cst Area, Mumbai-400001, Maharashtra, India
Other Info - 2FL0001

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