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  3. Rhinoprl Nasal Spray 9.8 ml

Rhinoprl Nasal Spray 9.8 ml, Pack of 1 NASAL SPRAY
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Composition :

AZELASTINE-140MCG + FLUTICASONE-50MCG

Manufacturer/Marketer :

Pristine Pearl Pharma Pvt Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Rhinoprl Nasal Spray

Rhinoprl Nasal Spray is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance. These foreign substances are known as 'allergens.' Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen or pet dander. One of the main symptoms of allergy is cough, which acts as a reflex action in the throat when there is any mucus or foreign irritant entering the respiratory system.

Rhinoprl Nasal Spray is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (antiallergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Together, both of them effectively treat allergic symptoms.

Take Rhinoprl Nasal Spray as advised by your doctor by spraying towards the sides of nostrils. Your doctor will recommend how often you take Rhinoprl Nasal Spray based on your medical condition. Some people may experience headaches, taste changes or nose bleeds. Most of these side effects of Rhinoprl Nasal Spray do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Rhinoprl Nasal Spray or any other medicines, are pregnant or breastfeeding before using Rhinoprl Nasal Spray . Rhinoprl Nasal Spray is not recommended for children below six years of age. If you experience vision changes, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Rhinoprl Nasal Spray and consult a doctor immediately. Avoid contact with people who have infections or are sick, as the Rhinoprl Nasal Spray may weaken the immune system, causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers, or sores inside the nose, inform your doctor before taking Rhinoprl Nasal Spray .

Side Effects of Rhinoprl Nasal Spray

  • Drowsiness
  • Headaches
  • Taste changes
  • Nose bleeds

Uses of Rhinoprl Nasal Spray

Treatment of Allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes.

Directions for Use

• Rhinoprl Nasal Spray is for nasal use only.• It is recommended to spray Rhinoprl Nasal Spray twice daily into each nostril, or as prescribed by your doctor.• Check the label for directions before using Rhinoprl Nasal Spray .• Shake the nasal spray bottle gently before each use.• Blow your nose and remove the protective cap. Before the first use, press the pump a few times until an even spray is released. • Insert the tip of the bottle into a nostril while closing the other nostril and spray the medicine into your nose. Keep your head straight and breathe gently. Repeat the same process for the other nostril.• If Rhinoprl Nasal Spray accidentally gets sprayed into your mouth or eyes, rinse with water thoroughly.

Medicinal Benefits

Rhinoprl Nasal Spray is primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. It combines two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose and sinus discomfort. On the other hand, Azelastine belongs to the antihistamines class (antiallergic drugs), which works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Together, both of them effectively treat allergic symptoms.

How Rhinoprl Nasal Spray Works

Rhinoprl Nasal Spray is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (antiallergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Together, both of them effectively treat allergic symptoms.

Storage

Keep Rhinoprl Nasal Spray out of the sight and reach of children.
Side effects of Rhinoprl Nasal Spray 9.8 ml
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

What if I have taken an overdose of Rhinoprl Nasal Spray

Do not use Rhinoprl Nasal Spray in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

Please inform your doctor if you are allergic to Rhinoprl Nasal Spray or any other medicines. Do not use the Rhinoprl Nasal Spray if you are pregnant or breastfeeding without consulting the doctor. Rhinoprl Nasal Spray is not recommended for children below six years of age. If you experience vision changes, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Rhinoprl Nasal Spray and consult a doctor immediately. Avoid contact with people who have infections or are sick as Rhinoprl Nasal Spray may weaken the immune system, causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers, or sores inside the nose, inform your doctor before taking Rhinoprl Nasal Spray .

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
FluticasoneAmprenavir
Severe

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Co-administration of Rhinoprl Nasal Spray 9.8 ml with Mifepristone may make Rhinoprl Nasal Spray 9.8 ml less effective as a therapy.

How to manage the interaction:
Taking Rhinoprl Nasal Spray 9.8 ml with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
FluticasoneAmprenavir
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Co-administration of Amprenavir and Rhinoprl Nasal Spray 9.8 ml may significantly increase the absorption of Rhinoprl Nasal Spray 9.8 ml into the blood stream.

How to manage the interaction:
Co-administration of Amprenavir and Rhinoprl Nasal Spray 9.8 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneTelithromycin
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
When Rhinoprl Nasal Spray 9.8 ml is taken with Telithromycin, it can lower the rate at which Telithromycin is broken down in the body.

How to manage the interaction:
Although there is a possible interaction between Rhinoprl Nasal Spray 9.8 ml and Telithromycin, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, strange fat distribution, bruising, infection, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneMibefradil
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Co-administration of Mibefradil may significantly increase the absorption of Rhinoprl Nasal Spray 9.8 ml into the bloodstream.

How to manage the interaction:
Taking Rhinoprl Nasal Spray 9.8 ml with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneCeritinib
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Taking Ceritinib together with Rhinoprl Nasal Spray 9.8 ml may increase the blood levels of Rhinoprl Nasal Spray 9.8 ml.

How to manage the interaction:
If you are supposed to take Rhinoprl Nasal Spray 9.8 ml and Ceritinib together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneConivaptan
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
When Conivaptan is taken with Rhinoprl Nasal Spray 9.8 ml, it can make Conivaptan break down faster in the body.

How to manage the interaction:
Co-administration of Conivaptan and Rhinoprl Nasal Spray 9.8 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneDinutuximab
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Co-administration of Dinutuximab and Rhinoprl Nasal Spray 9.8 ml may increase the risk of serious and potentially infections.

How to manage the interaction:
Co-administration of Dinutuximab and Rhinoprl Nasal Spray 9.8 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneItraconazole
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Coadministration of Itraconazole and Rhinoprl Nasal Spray 9.8 ml may significantly increase the absorption of Rhinoprl Nasal Spray 9.8 ml into the bloodstream.

How to manage the interaction:
Rhinoprl Nasal Spray 9.8 ml and itraconazole may interact, but if a doctor prescribes them, you can still use them. Swelling, high blood pressure, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, cataracts, irregular menstruation, and excessive face or body hair growth are all signs that you need to consult a doctor. Never discontinue taking a medication without consulting a doctor.
FluticasoneIndinavir
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Indinavir may increase the absorption of Rhinoprl Nasal Spray 9.8 ml into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Rhinoprl Nasal Spray 9.8 ml and Indinavir together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor.
FluticasonePosaconazole
Severe
How does the drug interact with Rhinoprl Nasal Spray 9.8 ml:
Co-administration of Rhinoprl Nasal Spray 9.8 ml with posaconazole may increase the level of Rhinoprl Nasal Spray 9.8 ml in the blood and increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Rhinoprl Nasal Spray 9.8 ml and posaconazole, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness, acne, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation and swelling in nasal passages.
  • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to relieve a runny nose, cough, and sneezing.
  • Stress affects the immune system and raises the risk of illness. To relieve stress, meditate, deepen breathing, and engage in regular exercise. You can also try progressive muscle relaxation techniques.
  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
  • Maintain personal hygiene and keep your surroundings clean.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

Rhinoprl Nasal Spray Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is unknown whether it is safe to consume alcohol with Rhinoprl Nasal Spray . However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

The safety of Rhinoprl Nasal Spray in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Rhinoprl Nasal Spray is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Rhinoprl Nasal Spray may cause drowsiness in some people. Therefore, drive only if you are alert after taking Rhinoprl Nasal Spray .

bannner image

Liver

Safe if prescribed

Inform your doctor before prescribing the Rhinoprl Nasal Spray if you have a history of liver impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Safe if prescribed

Inform your doctor before receiving the Rhinoprl Nasal Spray if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

Rhinoprl Nasal Spray is not recommended for children below six years as the safety and effectiveness were not established.

Have a query?

FAQs

Rhinoprl Nasal Spray is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes.

Rhinoprl Nasal Spray is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (antiallergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, runny nose, watery eyes, itching, swelling, congestion, or stiffness. Together, both of them effectively treat allergic symptoms.

It is recommended that you avoid taking grapefruit juice with Rhinoprl Nasal Spray as it may lead to adrenal insufficiency and Cushing’s syndrome (increased cortisol hormone in the body).

Your rhinitis symptoms may improve over several days of regular use. Call your healthcare provider if your symptoms do not improve or worsen.

You are not recommended to take more than the prescribed dose of Rhinoprl Nasal Spray or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck, and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while taking Rhinoprl Nasal Spray , please consult a doctor immediately.

No, you are recommended not to use Rhinoprl Nasal Spray if you have a recent nose operation or have any nose infections as it may lead to nose bleeding and excessive pain in the nose, leading to further worsening of your condition. Consult your doctor and do as advised for the best results.

No, Rhinoprl Nasal Spray is not used to treat asthma attacks. It is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to always carry a rescue inhaler to treat asthma attacks.

Rhinoprl Nasal Spray contains Fluticasone which belongs to the class of corticosteroids, and it may result in the development of glaucoma and/or cataracts. Therefore, close monitoring is warranted in patients with a change in vision or a history of increased intraocular pressure, glaucoma, and/or cataracts.

Use Rhinoprl Nasal Spray as advised by your doctor. Place the tip of the bottle into one nostril while closing the other nostril. Spray towards the side of your nostril, keeping your head upright and breathing in softly.

Store in a cool and dry place at room temperatures. Protect from light. Keep it out of reach of children. Do not refrigerate. Follow the local guidelines for disposal of Rhinoprl Nasal Spray .

Rhinoprl Nasal Spray causes side effects as headache, nose bleeds, and taste change. These side effects do not require any medical treatment. They will reduce by time.

Country of origin

INDIA

Manufacturer/Marketer address

81, 134, 4Th Main Rd, Keb Colony, New Gurappana Palya, Jayanagara 9Th Block, Btm Layout, Bengaluru, Karnataka 560029
Other Info - RHI0078

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:39 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/202236s008lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.9450.pdf
  3. https://www.drugs.com/cdi/azelastine-and-fluticasone.html

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