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compositionComposition:APIXABAN-5MG
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Prescription Medicine
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

APIXABAN-5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Abaxis 5 Tablet

Abaxis 5 Tablet is a prescription medicine anticoagulant (blood thinner) used to prevent and treat harmful blood clots. It helps reduce the risk of stroke in people with certain heart rhythm disorders and prevents clot-related complications such as deep vein thrombosis and pulmonary embolism. 

For the best results, you must take Abaxis 5 Tablet consistently every day at the exact times recommended by your healthcare provider. You can take this tablet with or without food, making it easy to fit into your daily routine. Staying hydrated and engaging in light, safe physical activities like walking can also help support healthy blood circulation while on this medication.

While taking Abaxis 5 Tablet , some people may experience mild side effects, with minor bleeding or bruising being the most common. It is crucial to monitor your body closely and consult your doctor immediately if you notice serious symptoms, such as unusual bleeding that will not stop, dark urine, or severe dizziness.

Do not take this if you have active, severe bleeding or a mechanical heart valve. Before starting Abaxis 5 Tablet , talk to your doctor if you have liver damage, kidney disease, or a history of bleeding disorders to ensure this treatment is safe for you.

This medicine can interact with other blood thinners, certain pain relievers like aspirin, and some herbal supplements, which can increase your risk of bleeding. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist about the risks and benefits before starting treatment.

Uses of Abaxis 5 Tablet

Abaxis 5 Tablet is used to prevent and treat harmful blood clots in different medical conditions. The uses of Abaxis 5 Tablet are as follows: 

  • Stroke prevention in non-valvular atrial fibrillation: Abaxis 5 Tablet helps prevent dangerous blood clots from forming in the heart and travelling to the brain, which significantly lowers the risk of a stroke in people with this irregular heart rhythm.
  • Treatment of deep vein thrombosis (DVT): This medicine helps prevent blood clots in the deep veins from becoming larger while allowing the body's natural processes to gradually break them down. It may also help reduce symptoms such as swelling and pain.
  • Treatment of pulmonary embolism (PE): Abaxis 5 Tablet treats life-threatening blood clots that have travelled to the lungs, helping to restore normal blood flow and breathing.
  • Prevention of recurrent DVT and PE: After initial treatment, this medication helps stop new blood clots from forming in the legs or lungs.
  • Prevention of blood clots after hip or knee replacement surgery: It protects patients who have limited mobility after major joint surgeries from developing harmful clots.

Key Benefits

Abaxis 5 Tablet contains apixaban, which helps prevent harmful blood clots from forming and reduces the risk of serious clot-related complications. Its benefits include:

  • Reduces Stroke Risk: Helps lower the risk of stroke and other clot-related complications in people with conditions that increase blood clot formation.
  • Prevents Blood Clots: Helps prevent the formation of blood clots in the legs, lungs, and other parts of the body.
  • Supports Recovery After Surgery: Helps reduce the risk of blood clots following major hip or knee replacement surgery, supporting a safer recovery.
  • No Routine Blood Monitoring Required: Unlike some older blood thinners, Abaxis 5 Tablet does not usually require frequent blood tests to monitor its effect.
  • Offers Convenient Long-Term Protection: Provides effective clot prevention without major dietary restrictions, making long-term treatment easier to manage.
Side effects of Abaxis 5 Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

Follow these clear steps to get the maximum benefit from treatment with Abaxis 5 Tablet safely:

  • Swallow the tablet whole with a full glass of water.
  • You may take this medication with or without food.
  • If you have trouble swallowing the tablet, talk to your doctor or pharmacist about crushing it and mixing it with water or applesauce.
  • Take this medicine at the exact same times every day to keep a steady amount in your body.
  • Always follow your doctor's exact instructions regarding how and when to take your medication. Do not change your dose or stop taking it without consulting them first.

How Abaxis 5 Tablet Works

To understand how Abaxis 5 Tablet works, it helps to think of your body's blood clotting process as a domino effect. When you get a cut, your body triggers a chain reaction of proteins to form a clot and stop the bleeding. One key protein in this chain is called Factor Xa. Abaxis 5 Tablet works by directly binding to and blocking Factor Xa. By turning off this specific protein, the medicine slows down your body's ability to form clots. This prevents dangerous blockages from forming in your blood vessels while still allowing your body to heal normally from minor scrapes.
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Alcohol

Unsafe

You are recommended not to consume more than 14 units per week as exceeding this may increase the risk of bleeding.

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Pregnancy

Consult your doctor

Abaxis 5 Tablet is a Category B pregnancy drug and is given to pregnant women only if doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Abaxis 5 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Safe if prescribed

Abaxis 5 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Abaxis 5 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Abaxis 5 Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Abaxis 5 Tablet is not recommended for children below 18 years of age as the safety and efficacy is not mentioned.

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Heart

Caution

Abaxis 5 Tablet can be used in heart patients if prescribed by the physician to reduce the risk of heart attack and stroke. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Abaxis 5 Tablet should be used in elderly patients only if recommended by the physician.

What if I have taken an overdose of Abaxis 5 Tablet

Do not take more than the prescribed dose of Abaxis 5 Tablet as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising, red/black/tarry stools, red/brown/pink urine and coughing up or vomiting blood or material that looks like coffee grounds. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Choose safe activities: Avoid contact sports or activities that carry a high risk of falling or head injury, as even minor injuries can cause serious internal bleeding.
  • Use personal care caution: Use a soft-bristled toothbrush and waxed dental floss to protect your gums. Use an electric razor instead of a manual blade to prevent skin cuts.
  • Keep diet consistent: Unlike older blood thinners, you do not need to avoid foods containing Vitamin K, but you should still avoid making sudden, extreme changes to your daily eating habits.
  • Limit alcohol intake: Drink alcohol only in moderation, if at all, as alcohol can increase your risk of stomach bleeding while on this medicine.
  • Stay active safely: Regular, low-impact exercise like walking helps maintain healthy circulation. Talk to your doctor before starting any new fitness routine.

Have a query?

How Soon It Starts Working

The time required for Abaxis 5 Tablet to start to work: Abaxis 5 Tablet ideally shows its action within 3 to 4 hours after administration. The time for which the effects of Abaxis 5 Tablet last: The effect of Abaxis 5 Tablet lasts for 24 hours.

What if you forget to take Abaxis 5 Tablet

If you miss a dose of Abaxis 5 Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Abaxis 5 Tablet tablets according to the instructions on the product packaging, generally at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Tell all healthcare providers: Always inform your dentists, surgeons, and other doctors that you are taking Abaxis 5 Tablet before any medical or dental procedure, as you may need to temporarily stop taking it.
  • Do not stop abruptly: Never stop taking this medication without your doctor's direct advice. Stopping suddenly can greatly increase your risk of forming a dangerous blood clot or suffering a stroke.
  • Monitor for bleeding: Check your body daily for unusual bruises, red or dark brown urine, or black stools, which can be early warning signs of internal bleeding.
  • Avoid self-medicating with pain relievers: Do not take over-the-counter pain medications like ibuprofen, naproxen, or aspirin unless specifically approved by your doctor, as they can double your bleeding risk.
  • Wear medical alert identification: Carry a medical alert card or wear a bracelet stating that you take Abaxis 5 Tablet so emergency responders are aware in an accident.

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Abaxis 5 Tablet :

  • Other Blood Thinners and NSAIDs: Taking Abaxis 5 Tablet with blood thinners such as heparin or warfarin, aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen may significantly increase the risk of bleeding.
  • Certain Antifungal Medicines: Medicines such as ketoconazole may increase Abaxis 5 Tablet levels in the body and raise the risk of bleeding.
  • Certain Seizure Medicines and St. John's Wort: Medicines such as carbamazepine and herbal products containing St. John's Wort may reduce the effectiveness of Abaxis 5 Tablet and increase the risk of blood clots.


Drug-Food Interactions

  • Alcohol: Excessive alcohol consumption may increase the risk of bleeding and should be avoided or limited. 


Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Abaxis 5 Tablet , as it may worsen your condition or require closer monitoring.

  • Active Bleeding: Abaxis 5 Tablet is not recommended for people with active bleeding because it may worsen bleeding and increase the risk of serious complications.
  • Severe Liver Disease: This medicine may not be suitable for individuals with severe liver damage due to an increased risk of bleeding.
  • Mechanical Heart Valves: Abaxis 5 Tablet is not recommended for people with mechanical heart valves.
  • Kidney Disease: Use this medicine with caution if you have kidney disease, as your doctor may need to adjust your treatment or monitor you more closely.
ApixabanDefibrotide
Critical

Drug-Drug Interactions

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ApixabanDefibrotide
Critical
How does the drug interact with Abaxis 5 Tablet:
Coadministration of Defibrotide and Abaxis 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Defibrotide and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Abaxis 5 Tablet:
Mifepristone and Abaxis 5 Tablet co-administration have been associated with more severe vaginal bleeding in women.

How to manage the interaction:
Taking Abaxis 5 Tablet with Mifepristone together is not generally recommended as it may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience persistent, excessive bleeding, consult the doctor. Without consulting a doctor, never stop taking any medication.
ApixabanPhenylbutazone
Severe
How does the drug interact with Abaxis 5 Tablet:
Coadministration of Phenylbutazone and Abaxis 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Phenylbutazone and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Abaxis 5 Tablet:
Coadministration of Dipyridamole and Abaxis 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Dipyridamole and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
ApixabanBoceprevir
Severe
How does the drug interact with Abaxis 5 Tablet:
Boceprevir may significantly increase the blood levels of Abaxis 5 Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Even though combining Boceprevir and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
ApixabanTipranavir
Severe
How does the drug interact with Abaxis 5 Tablet:
Coadministration of tipranavir and Abaxis 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining tipranavir and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
ApixabanTelithromycin
Severe
How does the drug interact with Abaxis 5 Tablet:
Telithromycin may significantly increase the blood levels of Abaxis 5 Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Even though combining Telithromycin and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Abaxis 5 Tablet:
Coadministration of Abciximab and Abaxis 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Abciximab and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
ApixabanSaquinavir
Severe
How does the drug interact with Abaxis 5 Tablet:
Saquinavir may significantly increase the blood levels of Abaxis 5 Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Even though combining Saquinavir and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Abaxis 5 Tablet:
Coadministration of Heparin and Abaxis 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Heparin and Abaxis 5 Tablet may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICOAGULANT/ANTITHROMBOTIC]

FAQs

Abaxis 5 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung). Additionally, it is used to prevent blood clots in patients with atrial fibrillation (irregular heartbeat). Abaxis 5 Tablet works by inhibiting the action of blood clotting factor (X a), which is an important element of blood clotting.

No, you are not recommended to take ibuprofen with Abaxis 5 Tablet as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, red or black tarry stools, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

No, you are usually not advised to have a tattoo or body piercing while taking Abaxis 5 Tablet as it may increase the risk of bleeding and infection. If you still wish to proceed further, contact your doctor so that the dose may be adjusted or any antibiotics may be prescribed and let the piercer or tattooist know in advance that you are on treatment with a blood thinner.

Yes, you are advised to stop taking Abaxis 5 Tablet a few days before surgery or procedure as Abaxis 5 Tablet may increase the risk of bleeding. Therefore, before having any procedure or any surgery, please inform your doctor that you are taking Abaxis 5 Tablet .

Yes, Abaxis 5 Tablet helps in reducing the risk of stroke and heart attack by preventing blood clots. Stroke is caused as blood clots break off and travel to brain.

No, you are not recommended to stop taking Abaxis 5 Tablet without consulting your doctor as it may worsen the condition. Therefore, take Abaxis 5 Tablet for as long as your doctor has prescribed it.

If you have difficulty swallowing the tablet whole, please consult your doctor about alternative methods for taking Abaxis 5 Tablet . The tablet can be crushed and mixed with water, 5% glucose in water, apple juice, or apple puree just before consumption.

If you miss a dose of Abaxis 5 Tablet , take it as soon as you remember. Take the next dose of Abaxis 5 Tablet at the usual time and then continue as normal.

Side effects of Abaxis 5 Tablet include nausea, anaemia (lack of blood), and unusual bleeding, including swelling and bruising. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you have atrial fibrillation (a condition in which the heart beats irregularly) and are taking Abaxis 5 Tablet to help prevent strokes or serious blood clots, in that case, you may be at a higher risk of having a stroke if you stop taking this medication. Besides this, you may be at risk of having a blood clot form in or around your spine that could cause paralysis if you have epidural or spinal anaesthesia or a spinal puncture while taking a blood thinner such as Abaxis 5 Tablet .

Yes, Abaxis 5 Tablet is a blood thinner. It belongs to the class of medicines known as factor Xa inhibitors which help prevent the formation of blood clots.

Symptoms of Abaxis 5 Tablet overdose are unusual bleeding or bruising; red, brown, or pink urine; red or black, tarry stools; and coughing up or vomiting blood or material that looks like coffee grounds. Consult the doctor if you experience these symptoms or if you have taken an overdose.

You should limit your alcohol intake while taking Abaxis 5 Tablet . Regular or heavy drinking can increase your risk of stomach ulcers and bleeding. Talk to your doctor about what is safe for you.

For minor cuts, apply firm, direct pressure with a clean cloth for at least 10 to 15 minutes. If the bleeding does not stop after applying pressure, or if you experience a severe injury, seek emergency medical help immediately. Talk to your doctor if you experience frequent bleeding.

Unlike older blood thinners, Abaxis 5 Tablet does not require routine, ongoing blood tests to monitor how quickly your blood clots. However, your doctor will still perform occasional blood tests to check your kidney and liver function. Talk to your doctor to learn more.

Abaxis 5 Tablet is generally not recommended during pregnancy or breastfeeding, as its safety for unborn babies and infants is not fully established, and it may increase the risk of bleeding. Your doctor will help you find a safer alternative. Talk to your doctor if you are pregnant or planning to become pregnant.

No, Abaxis 5 Tablet can be taken with or without food, and its absorption is not affected by meals. You do not need to restrict specific foods, but keeping a consistent diet is always recommended. Talk to your doctor if you have any dietary concerns.

Abaxis 5 Tablet does not directly dissolve blood clots. Instead, it prevents existing clots from getting larger and helps stop new clots from forming while your body's natural processes gradually break down the clot over time. Talk to your doctor for more information about your treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ABA0030
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