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compositionComposition:ACITRETIN-10MG
prescription
Prescription Medicine
info
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Acitin-10 Capsule 10's is used to treat psoriasis. It contains Acitretin, which slows down the progression of the disease. It slows the growth of skin cells and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes. It may cause side effects such as dry lips, skin peeling, skin scaling and thinning, skin reddening, and a burning or itching sensation on the skin.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACITRETIN-10MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Acitin-10 Capsule 10's

Acitin-10 Capsule 10's is an oral prescription medicine used to treat severe skin conditions, including severe plaque, pustular, and erythrodermic psoriasis. It is prescribed for cases that do not respond well to other treatments. The main purpose of this medicine is to control the rapid growth and accumulation of skin cells.

For the best results, you must take Acitin-10 Capsule 10's consistently once daily, exactly as directed by your healthcare provider. Always take this medicine with a main meal or with a glass of milk, as fat in your food helps your body absorb the medication much better. Additionally, incorporating a gentle moisturising routine and staying well-hydrated can significantly help manage dry skin during treatment.

While using this medication, you may experience common side effects like dry lips, peeling skin on your palms and soles, and dry eyes. If you develop serious side effects, such as a severe, persistent headache, yellowing of your skin or eyes, or sudden mood changes, you must consult your doctor immediately.

Before starting your treatment, talk to your doctor if you have a history of liver problems, high cholesterol, kidney disease, or diabetes. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Because of the extreme risk of severe birth defects, female patients must strictly avoid pregnancy during treatment and for three years after stopping this medicine.

This medicine can interact with several substances; for example, you must completely avoid alcohol because it converts the medication into a substance that stays in your body for years, increasing the risk of birth defects. Do not take vitamin A supplements, as they can lead to dangerous toxic build-up in your body. Always consult your doctor or pharmacist if you are an older adult or have other underlying health conditions before starting this treatment.

Uses of Acitin-10 Capsule 10's

Acitin-10 Capsule 10's is used to treat severe skin conditions, including severe plaque, pustular, and erythrodermic psoriasis. The detailed uses of Acitin-10 Capsule 10's are as follows:

  • Severe Psoriasis: Acitin-10 Capsule 10's helps control severe, widespread plaque psoriasis, pustular psoriasis, and erythrodermic psoriasis by slowing down the rapid multiplication of skin cells.
  • Severe Keratinisation Disorders: This medicine is used to treat severe skin scaling conditions, such as ichthyosis and Darier’s disease, by helping normal skin cells form correctly.

Key Benefits

Acitin-10 Capsule 10's provides profound relief for individuals struggling with severe, stubborn skin conditions that have not responded to other treatments. By targeting the root cause of rapid skin cell production, it delivers several key benefits:

  • Reduces Skin Scaling and Thickness: It noticeably thins and softens thick, scaly plaques, allowing your skin to regain a smoother, more comfortable texture.
  • Eases Pain and Itching: By reducing inflammation and clearing lesions, Acitin-10 Capsule 10's helps relieve the intense itching, cracking, and physical discomfort associated with severe psoriasis.
  • Clears Widespread Skin Lesions: Over time, this treatment helps clear large areas of affected skin, helping you feel more confident and comfortable in your daily life.
Side effects of Acitin-10 Capsule
  • Moisturize your nails with oil or lotion.
  • Cover your nails with gloves while cleaning utensils or other objects.
  • Maintain short, clean nails with gentle care.
  • Avoid damaging your nails by picking or biting.
  • Limit using nail polish and choose a gentle remover.
  • Wash hands with mild cleaner and warm water.
  • Refrain from using strong chemicals that can dry out your nails.
  • Wear long sleeves and pants to protect your fragile skin, especially when doing things like gardening or working outside.
  • Limit exposure to the sun, and when going outdoors, use sunscreen to avoid damaging your skin.
  • Keep your skin hydrated and protected by using moisturizing creams.
  • Use soft padding to cover sharp edges on furniture to prevent injuries.
  • Stop taking any medication that causes skin thinning, and if frequent skin tears occur, consult a doctor or dermatologist for further advice.
  • Consider taking protein and collagen supplements with your doctor's approval to slow skin thinning.
  • You can also take vitamin supplements, like A, B complex, C, D, and E, along with minerals like iron, zinc, biotin, selenium, and chromium, to improve your skin health.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.

Directions for Use

  • Acitin-10 Capsule 10's can be taken preferably with meals or a glass of milk as advised by a doctor.
  • It is advised to take Acitin-10 Capsule 10's once daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Acitin-10 Capsule 10's Works

Acitin-10 Capsule 10's contains acitretin, which belongs to a group of medicines called systemic retinoids, which are closely related to vitamin A. In people with severe psoriasis, the skin cells grow and multiply much faster than normal, leading to a buildup of thick, scaly patches. Acitin-10 Capsule 10's works by directly targeting the lifecycle of these skin cells. Once absorbed, it signals your body to slow down the hyperactive growth of skin cells. It encourages the cells to grow and mature normally instead of piling up on the surface of your skin. Additionally, it helps decrease the localised inflammation that causes redness, swelling, and discomfort. This dual action helps clear existing plaques and prevents new ones from forming.
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Alcohol

Unsafe

Acitin-10 Capsule 10's may interact with alcohol and increase the risk of side effects. So, it is not recommended to take alcohol, especially women of childbearing potential, during the treatment and at least 2 months after completing the treatment.

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Pregnancy

Unsafe

Acitin-10 Capsule 10's should not be used in pregnant women as it may cause harmful effects to the unborn baby or fetus. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Acitin-10 Capsule 10's should not be given to breastfeeding mothers as it may pass into breast milk and harm the nursing baby. Consult your doctor for further advice.

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Driving

Unsafe

Acitin-10 Capsule 10's may suddenly cause vision problems, especially in the dark. So, do not drive or operate heavy machinery if you notice any vision problems, especially at night.

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Liver

Caution

Acitin-10 Capsule 10's should not be used in patients with severe liver failure, as Acitin-10 Capsule 10's may cause liver damage. In mild to moderate liver disease, your doctor may need to adjust the dose.

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Kidney

Caution

Acitin-10 Capsule 10's should not be used in patients with severe kidney failure. In mild to moderate kidney disease, your doctor may need to adjust the dose.

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Children

Caution

Acitin-10 Capsule 10's should be used in children only if clinically needed, as it may affect growth and bone development. The dose may have to be adjusted by your doctor.

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Heart

Caution

Acitin-10 Capsule 10's should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Acitin-10 Capsule 10's.

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Geriatrics

Caution

Acitin-10 Capsule 10's can be given in elderly patients with extreme caution due to the risk of increased side effects

What if I have taken an overdose of Acitin-10 Capsule 10's

If you accidentally take too much of Acitin-10 Capsule 10's, seek immediate medical attention. Symptoms of an overdose may include severe headache, dizziness, vomiting, or extreme dry skin and lips.

Diet & Lifestyle Advise

  • Moisturise Frequently: Use thick, fragrance-free ointments or creams on your skin and petroleum jelly on your lips to combat the intense dryness caused by Acitin-10 Capsule 10's.
  • Protect Yourself from the Sun: This medicine makes your skin highly sensitive to sunlight. Wear protective clothing and wide-brimmed hats, and apply a broad-spectrum sunscreen with SPF 30 or higher daily. Avoid tanning beds.
  • Avoid Vitamin A Supplements: Do not take multivitamins or supplements containing vitamin A, as this can increase the risk of severe side effects from toxic buildup.
  • Stay Hydrated: Drink plenty of water throughout the day to help manage dry mouth, dry eyes, and skin dehydration.
  • Choose Gentle Skin Care: Avoid harsh soaps, scrubs, or chemical peels, which can severely irritate your already sensitive and thinning skin.
health query

Have a query?

How Soon It Starts Working

  • The time required for Acitin-10 Capsule 10's to start working: The time required for Acitin-10 Capsule 10's to show its effect is unknown.
  • The time for which the effects of Acitin-10 Capsule 10's last: The duration of action for Acitin-10 Capsule 10's is unknown.

What if you forget to take Acitin-10 Capsule 10's

If you miss a dose of Acitin-10 Capsule 10's, take it as soon as you remember, with food, on that same day. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Keep the capsules at room temperature, ideally between 15°C and 25°C (59°F to 77°F). •Store the medicine in its original container to protect it from light and moisture. Do not store it in the bathroom.

Drug Warnings

  • Strict Pregnancy Warning: Absolutely do not use Acitin-10 Capsule 10's if you are pregnant or planning to become pregnant. If you are of childbearing age, you must use two highly effective forms of birth control simultaneously for at least one month before starting, during the entire treatment, and for three full years after stopping.
  • Do Not Donate Blood: You must not donate blood while taking Acitin-10 Capsule 10's and for three years after your last dose. This prevents the medicine from being passed to a pregnant woman through a blood transfusion.
  • Avoid Alcohol Completely: Do not drink alcohol in any form during treatment and for two months after stopping. Alcohol causes the medicine to convert into a compound that stays in your body even longer, raising the risk of birth defects.
  • Avoid Night Driving: This medicine can affect your night vision. Be extremely cautious or avoid driving at night until you know how the treatment affects your eyes.
  • Monitor Your Labs: Attend all scheduled appointments for blood tests. Your doctor will need to monitor your liver function and cholesterol/lipid levels regularly while you take this medication.

Drug-Drug Interactions

verifiedApollotooltip
  • Methotrexate: May increase the risk of liver damage when combined with Acitin-10 Capsule 10's.
  • Tetracyclines: May increase the risk of increased pressure inside the skull, leading to severe headaches and vision changes.
  • Vitamin A Supplements: May cause toxic build-up and severe side effects similar to vitamin A overdose.
  • Low-dose Progestin Contraceptives: The effectiveness of 'mini-pills' may be reduced, increasing the risk of pregnancy.
AcitretinEtonogestrel
Critical
AcitretinMedroxyprogesterone
Critical

Drug-Drug Interactions

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AcitretinEtonogestrel
Critical
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Etonogestrel can increase the risk and severity of birth defects when taken in pregnant women.

How to manage the interaction:
Taking Acitin-10 Capsule with Etonogestrel together is generally avoided as it can result in an interaction which can be serious, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
AcitretinMedroxyprogesterone
Critical
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Medroxyprogesterone can increase the risk and severity of birth defects when taken by a pregnant woman.

How to manage the interaction:
Taking Acitin-10 Capsule with Medroxyprogesterone together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not discontinue any medications without consulting a doctor.
AcitretinLevonorgestrel
Critical
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Levonorgestrel can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.

How to manage the interaction:
Taking Acitin-10 Capsule with Levonorgestrel together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use Acitin-10 Capsule if you are pregnant. Do not stop using any medications without talking to a doctor.
AcitretinOxytetracycline
Critical
How does the drug interact with Acitin-10 Capsule:
Co-administration of Acitin-10 Capsule with Oxytetracycline can increase the risk of a rare and serious condition called pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Acitin-10 Capsule with Oxytetracycline together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinMinocycline
Critical
How does the drug interact with Acitin-10 Capsule:
Co-administration of Acitin-10 Capsule with Minocycline may increase the risk of a serious condition called pseudomotor cerebral (false brain tumour).

How to manage the interaction:
There's a possible interaction between Acitin-10 Capsule and Minocycline should be used together only if prescribed by a doctor. However, if you develop symptoms such as nausea, vomiting, headache, or visual disturbances during treatment with either medication, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
AcitretinDemeclocycline
Critical
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Demeclocycline can increase the risk and severity of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Acitin-10 Capsule with Demeclocycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinTetracycline
Critical
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Tetracycline can increase the risk and severity of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Acitin-10 Capsule with Tetracycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinDoxycycline
Critical
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Doxycycline can increase the risk and severity of vision problems.

How to manage the interaction:
Taking Acitin-10 Capsule with Doxycycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinEthanol
Critical
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Ethanol can increase the risk and severity of birth defects.

How to manage the interaction:
Taking Acitin-10 Capsule with Ethanol together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinLeflunomide
Severe
How does the drug interact with Acitin-10 Capsule:
Coadministration of Acitin-10 Capsule with Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Acitin-10 Capsule and Leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • High-Fat Meals: Significantly increase the absorption and effectiveness of Acitin-10 Capsule 10's in your body.
  • Alcohol: Must be avoided entirely, as it creates a harmful substance in your body that takes years to clear.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[RETINOIDS]

FAQs

Acitin-10 Capsule 10's is used to treat psoriasis, an autoimmune (immune system attacks healthy cells) skin disorder characterised by scaly, swollen, and itchy skin.
Acitin-10 Capsule 10's contains Acitretin, which belongs to the class of retinoids and is used to treat severe psoriasis. It has anti-inflammatory action and reduces the rashes, redness, scaling, and thickness. It also has antiproliferative properties and slows disease progression by slowing skin cell growth.
Acitin-10 Capsule 10's may suddenly cause vision problems, especially in the dark. So, inform your doctor immediately if you experience vision problems. Also, refrain from activities such as driving or operating heavy machinery if you have vision problems.
Acitin-10 Capsule 10's may not affect your immune system. It is not an immunosuppressant. It controls psoriasis by slowing its progression.
Acitin-10 Capsule 10's may affect blood glucose levels and should be used with caution in patients with diabetes. You may have to regularly monitor blood glucose levels while using this medicine.
No, Acitin-10 Capsule 10's is not an immunosuppressant. It belongs to the class of retinoids used to treat psoriasis.
Acitin-10 Capsule 10's may cause foetal harm; so, do not take Acitin-10 Capsule 10's if you are pregnant or plan to become pregnant within the next 3 years. Acitin-10 Capsule 10's may cause liver damage. Inform the doctor if you have or have ever had liver disease. Consult your doctor immediately if you experience symptoms of liver damage, such as nausea, vomiting, upper right abdominal pain, loss of appetite, yellowing of the skin or eyes, or dark urine.
Acitin-10 Capsule 10's may not affect semen. However, a small amount of Acitin-10 Capsule 10's is present in the semen of male patients who take this medication. Though it is not known if this affects the foetus, talk to your doctor about the risks of taking Acitin-10 Capsule 10's if your partner is pregnant or plans to become pregnant.
Take Acitin-10 Capsule 10's with the main meal. It should be swallowed as a whole with water; do not crush or chew it.
Avoid becoming pregnant and alcohol consumption during treatment with Acitin-10 Capsule 10's as it might affect the foetus. Do not donate blood while taking Acitin-10 Capsule 10's and for 3 years after treatment. Acitin-10 Capsule 10's may cause blurred vision; so, do not drive or operate machinery unless you are alert. Acitin-10 Capsule 10's may make your skin sensitive to sunlight; therefore, avoid prolonged exposure.
You must wait at least three years after stopping Acitin-10 Capsule 10's before trying to get pregnant. The medicine remains in your body's tissues for a very long time and can cause severe birth defects if you conceive during this period. Always use two reliable forms of birth control and talk to your doctor before planning a pregnancy.
When you mix alcohol with Acitin-10 Capsule 10's, it causes your body to create a chemical that takes years to leave your body and can cause severe birth defects long after you stop the medicine. You must avoid alcohol entirely during treatment and for two months after your last dose. Talk to your doctor if you need help avoiding alcohol.
No, you must not donate blood while taking Acitin-10 Capsule 10's and for three years after stopping. If your donated blood is given to a pregnant woman, it could cause severe birth defects in her baby. Talk to your doctor or pharmacist if you have questions about this restriction.
Yes, mild hair thinning or temporary hair loss is a common side effect of Acitin-10 Capsule 10's. In most cases, this hair loss is temporary, and your hair should return to normal after you finish your treatment. If you are concerned about hair thinning, talk to your doctor.
Your doctor will order regular blood tests to check your liver health and measure the levels of fats (cholesterol and triglycerides) in your blood. This medicine can sometimes affect liver function and increase blood fat levels, which your doctor needs to monitor to keep you safe. Talk to your doctor about your lab schedule.
No, you should avoid taking vitamin A supplements or multivitamins that contain vitamin A while using Acitin-10 Capsule 10's. Because this medicine is closely related to vitamin A, combining them can lead to a toxic buildup in your body, causing severe side effects. Talk to your doctor or pharmacist before taking any new supplements.
Dry skin and lips are very common during this treatment. You can manage this by applying thick, fragrance-free moisturisers and lip balms frequently throughout the day. Avoid hot showers and harsh soaps that can strip your skin of moisture. If the dryness becomes unmanageable or painful, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

125, Kandivli Industrial Estate, Kandivli (West), Mumbai – 400 067, Maharashtra, India.
Other Info - ACI0384

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