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compositionComposition:ESOMEPRAZOLE-40MG
prescription
Prescription Medicine
info
Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Invision Medi Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Actipraz-40 Tablet

Actipraz-40 Tablet is a prescription medication used to manage conditions caused by excessive stomach acid. It is commonly prescribed to treat gastroesophageal reflux disease (GERD), heal acid-related damage in the food pipe, and prevent stomach ulcers. By lowering the amount of acid your stomach produces, esomeprazole helps your digestive system heal.

To get the best results, you must take Actipraz-40 Tablet consistently at the same time every day, usually once daily. It is highly recommended to take this medicine on an empty stomach, at least one hour before a meal, as food can interfere with how it is absorbed. Combining this medication with simple lifestyle changes, such as eating smaller portions and avoiding late-night snacks, can significantly improve your recovery.

While taking this medicine, you might experience mild and temporary side effects such as headaches, gas, or mild diarrhoea. However, if you develop severe, watery diarrhoea, persistent stomach pain, or joint discomfort, you should contact your doctor right away.

Before starting this medication, talk to your doctor if you have severe liver damage, low magnesium levels, or osteoporosis. Do not take this medicine if you have had an allergic reaction to similar acid-reducing drugs, or if you are currently taking medications containing nelfinavir.

This medicine can affect how other drugs are absorbed in your stomach, particularly certain blood thinners, antifungals, and iron supplements, while alcohol and smoking can worsen your acid symptoms. If you are pregnant, breastfeeding, or an elderly individual, you should consult your doctor to ensure this medicine is appropriate for your specific needs.

Uses of Actipraz-40 Tablet

Actipraz-40 Tablet is used to manage conditions caused by excessive stomach acid and help protect the digestive tract from acid-related damage. The detailed uses of Actipraz-40 Tablet are as follows: 

  • Gastroesophageal Reflux Disease (GERD): Actipraz-40 Tablet helps by reducing the production of stomach acid, which prevents acid from flowing back into the food pipe and causing painful heartburn.
  • Erosive Esophagitis: Actipraz-40 Tablet helps heal the physical damage and irritation caused by stomach acid in the lining of your food pipe.
  • Stomach and Duodenal Ulcers: Actipraz-40 Tablet helps by lowering acid levels, which allows active ulcers to heal and prevents new ulcers from forming, especially if you are taking daily pain relief medications.
  • Zollinger-Ellison Syndrome: Actipraz-40 Tablet helps manage this rare condition by controlling the extremely high amounts of acid naturally produced by the stomach.
     

Key Benefits

Actipraz-40 Tablet contains esomeprazole, a proton pump inhibitor that helps reduce excess stomach acid, providing long-lasting relief from acid-related symptoms and protecting the digestive tract from further irritation. By controlling acid production throughout the day and night, it supports both symptom relief and healing.

  • Long-Lasting Relief from Heartburn and Acid Reflux: By reducing the amount of acid produced in the stomach, Actipraz-40 Tablet helps relieve the burning sensation of heartburn and discomfort associated with acid reflux, allowing you to eat, sleep, and carry out daily activities more comfortably.
  • Supports Healing of the Food Pipe: Lower stomach acid levels create a favourable environment for irritated or damaged oesophageal tissues to heal, helping reduce inflammation, discomfort, and pain while swallowing.
  • Protection Against Stomach Ulcers: Actipraz-40 Tablet helps protect the stomach lining from acid-related damage and may reduce the risk of ulcers, particularly in people who need long-term treatment with certain pain-relieving medicines.
     

Directions for Use

To ensure Actipraz-40 Tablet works effectively and safely, please follow these instructions:

  • Take this medicine exactly as prescribed by your doctor. Do not change your dose or stop taking it without consulting them first.
  • Take the capsule or tablet on an empty stomach, ideally at least one hour before your morning meal.
  • Swallow the medicine whole with a full glass of water. Do not crush, chew, or split the capsule or tablet, as this can destroy the protective coating designed to make it past your stomach acid safely.
  • If you have trouble swallowing capsules, talk to your doctor or pharmacist about safe alternative ways to take this medication.
     

How Actipraz-40 Tablet Works

Actipraz-40 Tablet contains esomeprazole, which belongs to a group of medicines known as proton pump inhibitors. Inside your stomach lining, there are tiny cellular pumps that produce the acid needed to digest food. When you take this medicine, it temporarily shuts down many of these pumps, directly reducing the total amount of acid your stomach makes. By lowering acid production, the medicine raises the pH levels inside your stomach. This makes the stomach fluids less acidic, meaning that any fluid that does splash back into your food pipe is much milder and will not cause burning or tissue damage. This acid control gives your digestive tract the necessary time to heal from irritation or ulcers.
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Alcohol

Caution

Drinking alcohol with Actipraz-40 Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Actipraz-40 Tablet .

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Pregnancy

Consult your doctor

Actipraz-40 Tablet is safe for use in pregnant women. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Consult your doctor

Actipraz-40 Tablet is safe for use in lactating mothers. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Driving

Caution

In some cases, Actipraz-40 Tablet may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Consult your doctor

Actipraz-40 Tablet should be taken with precaution in patients with liver disease. Please consult your physician.

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Kidney

Consult your doctor

Patients with kidney disease should consult a doctor before taking Actipraz-40 Tablet .

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Children

Caution

Actipraz-40 Tablet should not be prescribed for children under 5 years of age. Actipraz-40 Tablet is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

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Heart

Consult your doctor

Actipraz-40 Tablet should be taken with caution in patients with heart disease. Please consult your physician.

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Geriatrics

Safe

Actipraz-40 Tablet is safe for use in geriatric patients if prescribed by the physician.

What if I have taken an overdose of Actipraz-40 Tablet

Do not take more than the prescribed dose of Actipraz-40 Tablet as it may cause overdose. The symptoms of overdose include blurred vision, confusion, drowsiness, sweating, nausea, fast heartbeat, dry mouth, headache or flushing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Identify and Avoid Trigger Foods: Limit foods and beverages that may trigger acid reflux, such as spicy foods, citrus fruits, tomatoes, onions, chocolate, caffeine, and high-fat meals, as they can weaken the valve between the stomach and food pipe.
  • Eat Smaller, More Frequent Meals: Consume smaller meals throughout the day instead of large portions to help reduce pressure on the stomach and lower the risk of acid reflux.
  • Avoid Lying Down After Eating: Do not lie down, bend over, or go to bed for at least two to three hours after meals to help keep stomach acid from flowing back into the food pipe.
  • Elevate the Head of Your Bed: Raise the head of your bed by 6 to 9 inches using blocks or a wedge pillow to help prevent acid reflux while sleeping.
  • Wear Loose-Fitting Clothing: Choose loose-fitting clothes around the waist to avoid unnecessary pressure on the abdomen and stomach.
     

Have a query?

How Soon It Starts Working

The time required for Actipraz-40 Tablet to start to work: Actipraz-40 Tablet ideally shows its action within 1 hour after administration. The time for which the effects of Actipraz-40 Tablet last: The effect of Actipraz-40 Tablet lasts for 9 hours.

What if you forget to take Actipraz-40 Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for next dose, skip the missed dose and take next dose at regular time.

Storage

Store Actipraz-40 Tablet at room temperature, keeping it between 20°C and 25°C (68°F to 77°F). Keep the medication in its original container or blister pack to protect it from moisture and light. Do not store this medicine in the bathroom, near the kitchen sink, or in

Drug Warnings

  • Inspect the Medicine Before Use: Check the packaging before use to ensure the seals are intact and the tablets or capsules are not damaged or discoloured.
  • Attend Regular Health Monitoring: If you are taking this medicine for a long period, your doctor may recommend blood tests to monitor your magnesium and vitamin B12 levels.
  • Be Aware of Bone Health Risks: Long-term use of acid-reducing medicines may slightly increase the risk of bone fractures, particularly in the hip, wrist, or spine. Speak with your doctor about whether calcium and vitamin D supplementation is appropriate for you.
  • Avoid Prolonged Use Without Medical Advice: Do not take this medicine for longer than recommended by your doctor, as stopping it suddenly after prolonged use may cause increased stomach acid production.
  • Seek Medical Advice if Symptoms Persist: Contact your doctor if your symptoms do not improve after a few weeks of regular use or if they become worse.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Esomeprazole can affect how some medicines are absorbed or processed in the body, which may alter their effectiveness or increase the risk of side effects. Inform your doctor if you are taking any of the following medicines, as they may interact with Actipraz-40 Tablet :

  • Medicines Requiring Stomach Acid for Absorption: Actipraz-40 Tablet may reduce the absorption and effectiveness of medicines that require stomach acid to work properly, such as ketoconazole, itraconazole, nelfinavir, or atazanavir.
  • Medicines with Increased Blood Levels: Actipraz-40 Tablet may increase the levels and side effects of certain medicines, including diazepam, digoxin, and phenytoin.
  • Methotrexate: Taking Actipraz-40 Tablet with methotrexate may cause methotrexate to accumulate in the body and increase the risk of serious side effects.
  • Warfarin: Actipraz-40 Tablet may alter the blood-thinning effects of warfarin, and your doctor may need to monitor your blood clotting levels more closely.

Drug-Food Interactions

  • Food: Taking Actipraz-40 Tablet with food may delay and reduce its absorption, making it less effective. Take it on an empty stomach, preferably at least one hour before a meal.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Actipraz-40 Tablet , as it may worsen your condition or require additional monitoring:

  • Severe liver damage: Your liver processes this medicine; if your liver is not working well, the drug can build up, and your doctor may need to prescribe a lower dose.
  • Osteoporosis: Long-term use of this medicine can weaken bones, potentially worsening pre-existing osteoporosis or increasing fracture risk.
  • Lupus: This medicine may trigger or worsen symptoms of cutaneous lupus erythematosus, an autoimmune skin condition.
     
EsomeprazoleRilpivirine
Critical

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Actipraz-40 Tablet:
Actipraz-40 Tablet may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Actipraz-40 Tablet with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Actipraz-40 Tablet:
Taking tacrolimus with Actipraz-40 Tablet may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Actipraz-40 Tablet with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Actipraz-40 Tablet:
Taking nelfinavir with Actipraz-40 Tablet may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Actipraz-40 Tablet and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
How does the drug interact with Actipraz-40 Tablet:
Taking gefitinib with Actipraz-40 Tablet may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Actipraz-40 Tablet and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Actipraz-40 Tablet. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Actipraz-40 Tablet:
Actipraz-40 Tablet can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Actipraz-40 Tablet with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Actipraz-40 Tablet:
Coadministration of erlotinib and Actipraz-40 Tablet can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Actipraz-40 Tablet together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Actipraz-40 Tablet:
Co-administration of methotrexate and Actipraz-40 Tablet can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Actipraz-40 Tablet with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Actipraz-40 Tablet:
Coadministration of Clopidogrel with Actipraz-40 Tablet may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Actipraz-40 Tablet together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Actipraz-40 Tablet:
Actipraz-40 Tablet reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between Actipraz-40 Tablet and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Actipraz-40 Tablet:
Combining Actipraz-40 Tablet with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Actipraz-40 Tablet with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTACIDS]

FAQs

Actipraz-40 Tablet is used to treat Hyperacidity, Heartburn, Stomach ulcer, and Zollinger-Ellison syndrome.

Actipraz-40 Tablet is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.

No. Actipraz-40 Tablet prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Yes. Actipraz-40 Tablet can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.

There's no firm evidence to suggest that taking Actipraz-40 Tablet will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.

You can eat and drink normally while taking Actipraz-40 Tablet . However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.

Prolonged intake of Actipraz-40 Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

Actipraz-40 Tablet should be used in children only if prescribed by the doctor. Please consult the doctor before giving Actipraz-40 Tablet to children.

Actipraz-40 Tablet should be taken an hour before meals.

Actipraz-40 Tablet is usually taken on an empty stomach, first thing in the morning. If you take Actipraz-40 Tablet twice a day, take 1 dose in the morning and 1 dose in the evening.

Yes, Actipraz-40 Tablet can be taken with domperidone if prescribed by the doctor.

Do not discontinue Actipraz-40 Tablet without consulting your doctor. To treat your condition effectively, take Actipraz-40 Tablet for the duration prescribed by the physician.

Yes, Actipraz-40 Tablet is safe to use if prescribed by the doctor.

Actipraz-40 Tablet can be taken with ranitidine if prescribed by the doctor. No interactions were found between both the medicines.

If you miss a dose of Actipraz-40 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Actipraz-40 Tablet might cause side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen.

Consult the doctor before taking other medicines while using Actipraz-40 Tablet to prevent interactions. Let the doctor know if you are taking blood thinners, antifungal agents, anti-HIV drugs, anti-viral drugs, iron supplements, antibiotics, cardiac medicines and anti-cancer drugs.

No, you should take Actipraz-40 Tablet on an empty stomach, at least one hour before eating, as food can reduce how much of the medicine your body absorbs. Talk to your doctor or pharmacist if you have questions about the timing of your medication.

Esomeprazole may begin to provide some symptom relief within 1 to 2 hours, but it can take up to 2 to 4 days of consistent, daily use to reach its full acid-reducing effect. If your symptoms do not improve, talk to your doctor.

While Actipraz-40 Tablet is highly effective, taking it long-term (especially for more than a year) can increase the risk of side effects like low magnesium, vitamin B12 deficiency, and bone fractures. Your doctor will prescribe it for the shortest time necessary; talk to your doctor about your treatment duration.

No, you should swallow the capsule or tablet whole. Crushing, chewing, or breaking it can destroy the special coating that protects the medicine from being deactivated by your stomach acid. If you have difficulty swallowing, talk to your doctor or pharmacist for alternative options.

Although alcohol does not directly stop Actipraz-40 Tablet from working, alcohol can irritate your stomach lining and worsen your acid reflux or heartburn symptoms. For best results, it is highly recommended to limit or avoid alcohol; talk to your doctor for advice.

Weight gain is not a common or direct side effect of Actipraz-40 Tablet . However, because the medicine relieves stomach pain and acid reflux, you may find it easier or more comfortable to eat, which could indirectly lead to weight changes. If you experience sudden or unexplained weight changes, talk to your doctor.

Mild, short-term diarrhoea can sometimes occur. However, if you develop severe, watery, or persistent diarrhoea accompanied by stomach cramps and fever, stop taking the medicine and call your doctor immediately, as this could be a sign of a serious bacterial infection. Talk to your doctor before taking any anti-diarrhoea medicine.

Yes, in most cases you can safely take an occasional antacid for rapid, temporary relief while waiting for Actipraz-40 Tablet to take full effect. However, you should space them out and discuss this with your doctor or pharmacist first to ensure there are no specific issues with your treatment plan.

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Country of origin

India

Manufacturer/Marketer address

20Th Km, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - ACT0716
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