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compositionComposition:ENZALUTAMIDE-160MG
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Adleap Tablet 7's is used to treat prostate cancer. It contains Enzalutamide, an androgen receptor blocker (inhibitor) that blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow; this can slow the growth of the cancer and may shrink it. Enzalutamide is only for use in men. Men using this medication must use effective birth control whenever they have sex during their treatment and for three months after their final dose.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ENZALUTAMIDE-160MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Adleap Tablet 7's

Adleap Tablet 7's is a prescription medicine primarily used to treat advanced types of prostate cancer. It is designed for prostate cancer that has spread to other parts of the body or no longer responds to medical or surgical treatments that lower testosterone. This medicine works by stopping hormone signals that would otherwise allow cancer cells to grow and multiply.

To get the best results, you must take Adleap Tablet 7's consistently every single day at the same time as prescribed. You can take this medicine with or without food, making it easy to fit into your daily routine. Making small adjustments to your daily life, such as incorporating gentle physical activity and eating a balanced diet, can help your body handle the therapy more effectively.

While taking this medicine, you may experience common side effects like hot flashes, fatigue, and joint discomfort. However, you must contact your doctor immediately if you experience severe symptoms such as sudden confusion, severe dizziness, chest pain, or seizures.

Before starting Adleap Tablet 7's, you must talk to your doctor if you have a history of seizures, brain injury, stroke, heart disease, or high blood pressure. Do not take this if you are allergic to Adleap Tablet 7's or any of the inactive ingredients contained in the tablet.

This medicine can interact with other drugs like blood thinners and certain heart medicines, which may change how well they work or increase side effects. It is not approved for use in women, and pregnant or breastfeeding individuals must not handle or touch the tablets. Elderly patients should talk to their doctor to closely monitor their physical strength and heart health, taking extra precautions against falls due to the combined risk of dizziness, fatigue, and bone weakening.

Uses of Adleap Tablet 7's

Adleap Tablet 7's is used to treat advanced prostate cancer. The detailed uses of Adleap Tablet 7's are as follows:

  • Non-metastatic castration-resistant prostate cancer (nmCRPC): Adleap Tablet 7's treats prostate cancer that is 'castration-resistant' (meaning it continues to grow despite very low testosterone levels) and has not yet spread to other body parts on scans.
  • Metastatic castration-sensitive prostate cancer (mCSPC): Treats prostate cancer that has spread to other body parts (such as bones or lymph nodes) but still responds to medical or surgical treatments that lower testosterone.
  • Metastatic castration-resistant prostate cancer (mCRPC): Treats advanced prostate cancer that has spread to other parts of the body and no longer responds to initial testosterone-lowering treatments.

Key Benefits

Adleap Tablet 7's helps slow the progression of advanced prostate cancer and supports long-term disease management. The key benefits of Adleap Tablet 7's are as follows:

  • Slows Cancer Progression: By blocking the hormones that fuel tumour growth, Adleap Tablet 7's helps slow the progression of advanced prostate cancer, reduces cancer-related pain, and helps prevent the disease from spreading further.
  • Prolongs Survival and Delays Intensive Treatment: Clinical studies have shown that Adleap Tablet 7's helps prolong survival and may delay the need for more intensive treatments, such as chemotherapy, allowing many patients to maintain their independence and daily routine for longer.

Directions for Use

  • Adleap Tablet 7's can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Adleap Tablet 7's as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Adleap Tablet 7's Works

Adleap Tablet 7's contains enzalutamide, which belongs to a group of medicines called androgen receptor inhibitors. Male hormones, such as testosterone, act as fuel for prostate cancer cells by attaching to specific receptors on the cancer cells and stimulating their growth. Adleap Tablet 7's blocks these androgen receptors, preventing testosterone and other male hormones from attaching to them. This interrupts the growth signals that cancer cells rely on, helping slow the spread of prostate cancer, shrink tumours, and reduce prostate-specific antigen (PSA) levels.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Adleap Tablet 7's.

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Pregnancy

Not applicable

Enzalutamide is only for use in men. Women should not take this medication.

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Breast Feeding

Not applicable

Enzalutamide is only for use in men. Women should not take this medication.

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Driving

Unsafe

Adleap Tablet 7's may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

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Kidney

Caution

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

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Children

Unsafe

The safety and effectiveness of Adleap Tablet 7's in pediatric patients have not been established.

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Heart

Caution

Adleap Tablet 7's may increase the risk of heart problems. Therefore, please consult your doctor if you have any heart-related problems before using Adleap Tablet 7's.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Adleap Tablet 7's to geriatric patients. Your doctor will prescribe Adleap Tablet 7's if the benefits outweigh the risks.

What if I have taken an overdose of Adleap Tablet 7's

If you accidentally take more than your prescribed dose, seek emergency medical care immediately. An overdose can increase your risk of severe side effects, especially seizures.

Diet & Lifestyle Advise

  • Protect your bones: Since hormone therapies can weaken bones, talk to your doctor about taking calcium and vitamin D supplements to lower your risk of bone loss and fractures.
  • Discuss fertility options early: Because Adleap Tablet 7's can significantly impair sperm production and male fertility, speak with your oncologist before starting therapy if family planning is important to you, and consider options like sperm banking.
  • Stay active safely: Regular, low-impact exercise like daily walking can help reduce treatment-related fatigue and maintain your muscle strength.
  • Manage hot flashes: Wear loose, layered clothing made from natural fibres like cotton, and limit triggers like hot beverages, spicy foods, alcohol, and caffeine.
  • Monitor your blood pressure: Keep a regular home log of your blood pressure readings, as this medicine can cause your numbers to rise. Share these readings with your healthcare team.
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How Soon It Starts Working

The time required for Adleap Tablet 7's to start to work: Adleap Tablet 7's ideally shows its action within 1 hour after administration. The time for which the effects of Adleap Tablet 7's last: The duration of action for Adleap Tablet 7's is unknown.

What if you forget to take Adleap Tablet 7's

If you forget to take your dose of Adleap Tablet 7's, take it as soon as you remember on that same day. If you do not remember until the next day, skip the missed dose entirely and take your regular dose at your usual time. Do not take two doses at once to make up for a missed one. If you miss doses for multiple days, talk to your doctor or pharmacist for advice.

Storage

• Store Adleap Tablet 7's at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Be aware of seizure and fall risks: This medicine can increase your risk of seizures, severe dizziness, and fatigue. Take extra precautions to prevent falls, and avoid activities like driving, climbing, or operating heavy machinery if you feel lightheaded.
  • Handle with care: Pregnant women, those planning a pregnancy, or breastfeeding individuals should not touch or handle broken, cracked, or damaged tablets of Adleap Tablet 7's to prevent the drug from absorbing through the skin.
  • Use reliable birth control and consider fertility: If you are sexually active with a female partner who could become pregnant, you must use a highly effective birth control method (such as a condom) during treatment and for 3 months after your last dose. Because Adleap Tablet 7's can impair male fertility, discuss sperm banking options with your doctor before starting treatment if desired.
  • Inspect your tablets: Always check your pills before taking them. Do not take any tablets that look damaged, broken, or moist.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners: Taking Adleap Tablet 7's with medicines like warfarin can alter how your blood clots, increasing your risk of bleeding or reducing the drug's effectiveness.
  • Seizure medicines: Combining this medicine with certain anticonvulsants can lower the seizure threshold or affect how both medicines work.
  • Certain heart, cholesterol, and daily medicines: Adleap Tablet 7's is a strong liver enzyme inducer, meaning it speeds up how your liver processes many other medicines, making them less effective. Your doctor will regularly monitor your liver function and review all your medicines.
EnzalutamideLurasidone
Critical
EnzalutamideDronedarone
Critical

Drug-Drug Interactions

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EnzalutamideLurasidone
Critical
How does the drug interact with Adleap Tablet:
Co-administration of Lurasidone with Adleap Tablet may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Adleap Tablet is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideDronedarone
Critical
How does the drug interact with Adleap Tablet:
Co-administration of Adleap Tablet and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Adleap Tablet and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideZiprasidone
Critical
How does the drug interact with Adleap Tablet:
Taking Adleap Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Adleap Tablet with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideRegorafenib
Critical
How does the drug interact with Adleap Tablet:
Taking Adleap Tablet with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Adleap Tablet with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideRanolazine
Critical
How does the drug interact with Adleap Tablet:
Taking Adleap Tablet may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Adleap Tablet with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideDroperidol
Severe
How does the drug interact with Adleap Tablet:
Taking Adleap Tablet and Droperidol together can increase the chance of a serious abnormal heart rhythm. If you suffer from any heart conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Adleap Tablet and Droperidol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, drowsiness, confusion, muscle pain, nausea, or vomiting or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideMifepristone
Severe
How does the drug interact with Adleap Tablet:
Co-administration of Adleap Tablet with mifepristone can increase the risk of irregular heart rhythms. Low potassium levels may also result from prolonged therapy with mifepristone

How to manage the interaction:
Taking Adleap Tablet with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, irregular heartbeat, nausea, vomiting, constipation, abdominal cramping, confusion, muscle cramps, numbness or tingling, chest pain, and/or swelling in the legs or feet, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideBupropion
Severe
How does the drug interact with Adleap Tablet:
Bupropion is capable of causing seizures(fits) and combining it with Adleap Tablet, may enhance the risk.

How to manage the interaction:
Taking bupropion along with Adleap Tablet can lead to an interaction, it can be taken if recommended by a doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
EnzalutamideErlotinib
Severe
How does the drug interact with Adleap Tablet:
Taking Adleap Tablet with Erlotinib may decrease the blood levels of Erlotinib, which may make Erlotinib less effective.

How to manage the interaction:
Although taking Adleap Tablet and Erlotinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EnzalutamideTofacitinib
Severe
How does the drug interact with Adleap Tablet:
Co-administration of Adleap Tablet and Tofacitinib may decrease the blood levels of Tofacitinib, which may make Tofacitinib less effective.

How to manage the interaction:
Although taking Adleap Tablet and Tofacitinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Caffeine: Limit high amounts of caffeine, as it can worsen hot flashes, raise your blood pressure, or interfere with your sleep patterns during treatment.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Adleap Tablet 7's is used to treat prostate cancer in men.
Most prostate cancers require testosterone to grow. Adleap Tablet 7's contains Enzalutamide, which blocks testosterone, a hormone, from reaching prostate cancer cells. Thus, Adleap Tablet 7's can slow the cancer's growth and cause it to shrink.
Adleap Tablet 7's is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.
In some cases, Adleap Tablet 7's may cause decreased fertility in men. However, you should not assume that your female partner cannot become pregnant. Please discuss with your doctor if you have any concerns.
Seizures may occur in patients receiving Adleap Tablet 7's. So, patients who have had a seizure, please inform your doctor about your condition. Your doctor may monitor your condition closely.
Yes, you can take Adleap Tablet 7's with or without food. Taking it at the same time every morning or evening is the best way to help you remember your dose. Talk to your doctor or pharmacist if you need help planning your schedule.
Adleap Tablet 7's does not cure prostate cancer, but it is highly effective at slowing down the growth and spread of the disease. This helps control your symptoms and prolongs survival. Talk to your doctor to understand your specific treatment goals.
Dizziness is a known side effect of this medicine. If you feel dizzy, sit or lie down immediately, and avoid driving or operating tools until you feel completely clear-headed. Talk to your doctor if the dizziness does not go away.
If your partner is pregnant, planning to become pregnant, or breastfeeding, they must not handle or touch Adleap Tablet 7's tablets, especially if they are broken or damaged, as the medicine can be absorbed through the skin. Talk to your doctor or pharmacist if you have concerns about safe handling.
Your doctor will keep you on Adleap Tablet 7's as long as it continues to effectively control your cancer and you tolerate the medicine well. Your progress will be tracked through regular blood tests (including PSA and liver function checks), blood pressure monitoring, and periodic imaging. If the cancer eventually progresses, your doctor will guide you through subsequent options—such as chemotherapy or other targeted therapies—noting that cross-resistance can occur with similar hormone therapies like abiraterone. Talk to your doctor about what to expect during your follow-up visits.
This medicine works by lowering the effects of male hormones, which can naturally lead to weaker bones and joint pain. Talk to your doctor about safe over-the-counter pain relievers or if you need calcium and vitamin D supplements to protect your bones.
Yes, if your partner can become pregnant, you must use highly effective birth control, such as condoms, during your treatment and for 3 months after you take your final dose. Talk to your doctor if you have questions about family planning.
It is highly recommended to limit or avoid alcohol while taking Adleap Tablet 7's, as alcohol can worsen side effects like dizziness, hot flashes, and liver strain. Talk to your doctor or pharmacist for personalised guidance regarding alcohol use.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Adley Formulation, Sco- 42, Sector 12, Panchkula-134112, Haryana, India
Other Info - ADL0041
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