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  3. Aggramed 5mg Infusion 100 ml

Aggramed 5mg Infusion 100 ml, Pack of 1 Injection
Aggramed 5mg Infusion 100 ml, Pack of 1 Injection
Aggramed 5mg Infusion 100 ml, Pack of 1 Injection
Aggramed 5mg Infusion 100 ml, Pack of 1 Injection
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Composition :

TIROFIBAN-5MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Aggramed 5mg Infusion

Aggramed 5mg Infusion belongs to a class of medicines called 'antiplatelets' (blood thinners) used to prevent blood clots. It helps to prevent heart attack and chest pain. It is intended for use with unfractionated heparin and aspirin. A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they are harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs.

Aggramed 5mg Infusion contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Aggramed 5mg Infusion will be administered by a healthcare professional; do not self-administer. Sometimes, Aggramed 5mg Infusion may cause common side effects such as bleeding under the skin at the site of injection or into a muscle causing swelling, bleeding after surgery, invisible blood in stool or urine, headache or feeling sick. Most of these side effects of Aggramed 5mg Infusion do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tirofiban or any other medicines, please tell your doctor. Aggramed 5mg Infusion is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Aggramed 5mg Infusion . Avoid alcohol consumption with Aggramed 5mg Infusion as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving Aggramed 5mg Infusion .

Uses of Aggramed 5mg Infusion

Aggramed 5mg Infusion is used in the prevention of blood clots, heart attack, and chest pain. The detailed uses of Aggramed 5mg Infusion are as follows:<br/>• Prevention of Blood Clots: Aggramed 5mg Infusion prevents platelets from aggregating and forming blood clots in the coronary arteries, reducing the risk of thrombotic events.<br/>• Prevention of Heart Attack: By inhibiting platelet aggregation, Aggramed 5mg Infusion reduces the risk of myocardial infarction (heart attack) in patients with acute coronary syndromes.<br/>• Management of Chest Pain: Aggramed 5mg Infusion helps to manage chest pain associated with acute coronary syndromes by preventing further platelet aggregation and clot formation, thereby reducing the risk of cardiac ischemic events.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Aggramed 5mg Infusion will be administered by the doctor or healthcare professional in a medical setting.• Do not self-administer.

Medicinal Benefits

Aggramed 5mg Infusion contains Tirofiban, an antiplatelet which prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. Also, it helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

How Aggramed 5mg Infusion Works

Aggramed 5mg Infusion contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Aggramed 5mg Infusion 100 ml
  • Apply an ice pack to slow bleeding and reduce swelling.
  • Keep your head raised to help blood drain away from your eye.
  • Take rest and avoid intense activities that raise pressure in the eye.
  • If the bleeding is severe or does not improve within 24 hours, consult a doctor.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.

What if I have taken an overdose of Aggramed 5mg Infusion

Since Aggramed 5mg Infusion is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

If you are allergic to Tirofiban or any other medicines, please tell your doctor. Aggramed 5mg Infusion is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Aggramed 5mg Infusion . Avoid alcohol consumption with Aggramed 5mg Infusion as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving Aggramed 5mg Infusion . If you have had cardiopulmonary resuscitation (CPR), a biopsy, or a procedure to break up kidney stones within the last 2 weeks or have been seriously injured, had a major operation or had an ulcer in the stomach or intestine within the last 3 months, had a recent spinal procedure, have history or symptoms of aortic dissection (splitting of the aorta, main artery), or had a special intravenous line inserted under your collar bone within the last 24 hours, inform your doctor before receiving Aggramed 5mg Infusion .

Drug-Drug Interactions

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TirofibanDabigatran etexilate
Severe
TirofibanDasatinib
Severe

Drug-Drug Interactions

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TirofibanDabigatran etexilate
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Taking Dabigatran etexilate with Aggramed 5mg Infusion 100 ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Aggramed 5mg Infusion 100 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
TirofibanDasatinib
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Using dasatinib together with Aggramed 5mg Infusion 100 ml may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Aggramed 5mg Infusion 100 ml with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TirofibanClopidogrel
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Taking Clopidogrel with Aggramed 5mg Infusion 100 ml can make the antiplatelet effects of Aggramed 5mg Infusion 100 ml stronger.

How to manage the interaction:
There may be a possibility of interaction between Aggramed 5mg Infusion 100 ml and Clopidogrel, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting your doctor.
TirofibanDalteparin
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Combining Aggramed 5mg Infusion 100 ml with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Aggramed 5mg Infusion 100 ml may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
TirofibanFondaparinux
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Taking Aggramed 5mg Infusion 100 ml with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Fondaparinux and Aggramed 5mg Infusion 100 ml, it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TirofibanEnoxaparin
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Combining Aggramed 5mg Infusion 100 ml with Enoxaparin can increase the risk of bleeding.

How to manage the interaction:
Taking Enoxaparin with Aggramed 5mg Infusion 100 ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away back pain, numbness, constipation, bleeding, bruises, dizziness, lightheaded, red or black stools, severe headache, weakness, or vomiting blood. Do not discontinue any medications without consulting a doctor.
TirofibanApixaban
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Coadministration of Aggramed 5mg Infusion 100 ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Aggramed 5mg Infusion 100 ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
TirofibanHeparin
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Taking Aggramed 5mg Infusion 100 ml with Heparin can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Heparin and Aggramed 5mg Infusion 100 ml, you can take these medicines together if prescribed by a doctor. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TirofibanPrasugrel
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Co-administration of Aggramed 5mg Infusion 100 ml with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Aggramed 5mg Infusion 100 ml and Prasugrel, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
TirofibanWarfarin
Severe
How does the drug interact with Aggramed 5mg Infusion 100 ml:
Coadministration of warfarin with Aggramed 5mg Infusion 100 ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Aggramed 5mg Infusion 100 ml and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor to avoid medication interactions.
  • Include foods high in antioxidants, such as vegetables, fruits, olive oil, seeds, nuts, cocoa, and red wine, as they may lower the risk of developing blood clots.
  • Adopt an anti-inflammatory diet high in omega-3-rich foods, fruits and vegetables, and vitamin E-rich foods.
  • Drink plenty of fluids as dehydration can thicken blood leading to an increased risk of blood clot formation.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid alcohol consumption as it may increase the risk of bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Aggramed 5mg Infusion Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid the consumption of alcohol with Aggramed 5mg Infusion as it may increase the risk of bleeding in the stomach or intestines.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Aggramed 5mg Infusion in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Aggramed 5mg Infusion . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Aggramed 5mg Infusion on breastfeeding mothers. Hence, if you are a nursing mother, inform your doctor before receiving Aggramed 5mg Infusion . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Due to your disease state, you will not be able to drive or operate machinery while receiving Aggramed 5mg Infusion .

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Liver

Caution

Aggramed 5mg Infusion is not recommended if you have severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving Aggramed 5mg Infusion .

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Kidney

Caution

If you have kidney disease/condition, inform your doctor before receiving Aggramed 5mg Infusion . The dose may be adjusted in patients with severe kidney failure.

bannner image

Children

Unsafe

Aggramed 5mg Infusion is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

Aggramed 5mg Infusion is used to prevent blood clots, heart attack and chest pain.

Aggramed 5mg Infusion contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Aggramed 5mg Infusion is not recommended for patients with severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving Aggramed 5mg Infusion .

Yes, Aggramed 5mg Infusion may cause bleeding. If you notice blood in urine or stool or coughing up blood, please inform your doctor immediately, as these might be signs of internal bleeding.

While taking Aggramed 5mg Infusion , avoid medications such as NSAIDs (aspirin, ibuprofen), anticoagulants (heparin, warfarin), thrombolytic agents (streptokinase), other antiplatelet medicines (clopidogrel), and SSRIs (citalopram), as they may interact with Aggramed 5mg Infusion and cause negative complications. Always inform your doctor about your medication and health history for personalized guidance.

Aggramed 5mg Infusion is administered through an intravenous (IV) infusion by a healthcare professional.

You should avoid consuming alcohol while on Aggramed 5mg Infusion since it may raise the risk of bleeding in the stomach or intestines.

Aggramed 5mg Infusion gets to work quickly, and you may start feeling better within a few hours. As the medication rapidly prevents blood clots, you'll be on the road to recovery in no time. Follow your doctor's instructions and complete the full treatment course to ensure maximum benefits and a speedy return to health.

The common side effects of the Aggramed 5mg Infusion may include bleeding under the skin at the site of injection or into a muscle, causing swelling, bleeding after surgery, invisible blood in stool or urine, headache, or feeling sick. Most of these side effects of Aggramed 5mg Infusion do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Zydus Cadila House, TPS 5, Plot No 360, Service Road, Vile Parle East-400057.
Other Info - AGG0001

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5519.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/1998/20912lbl.pdf
  3. https://www.nps.org.au/assets/medicines/85512a05-d881-4dba-9e2b-a9c300a9d889.pdf

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