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  3. AGGRIBLOC 5MG I.V INJECTION 100ML

AGGRIBLOC 5MG I.V INJECTION 100ML, Pack of 1 INJECTION
AGGRIBLOC 5MG I.V INJECTION 100ML, Pack of 1 INJECTION
AGGRIBLOC 5MG I.V INJECTION 100ML, Pack of 1 INJECTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

AGGRIBLOC 5MG I.V INJECTION 100ML is used to Prevent blood clots, heart attacks, and chest pain. It contains Tirofiban, an antiplatelet that prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. It also helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

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Composition :

TIROFIBAN-5MG

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About AGGRIBLOC 5MG I.V INJECTION 100ML

AGGRIBLOC 5MG I.V INJECTION 100ML belongs to a class of medicines called 'antiplatelets' (blood thinners) used to prevent blood clots. It helps to prevent heart attack and chest pain. It is intended for use with unfractionated heparin and aspirin. A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they are harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs.

AGGRIBLOC 5MG I.V INJECTION 100ML contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

AGGRIBLOC 5MG I.V INJECTION 100ML will be administered by a healthcare professional; do not self-administer. Sometimes, AGGRIBLOC 5MG I.V INJECTION 100ML may cause common side effects such as bleeding under the skin at the site of injection or into a muscle causing swelling, bleeding after surgery, invisible blood in stool or urine, headache or feeling sick. Most of these side effects of AGGRIBLOC 5MG I.V INJECTION 100ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tirofiban or any other medicines, please tell your doctor. AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML. Avoid alcohol consumption with AGGRIBLOC 5MG I.V INJECTION 100ML as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

Uses of AGGRIBLOC 5MG I.V INJECTION 100ML

Prevention of blood clots, heart attack and chest pain

Directions for Use

AGGRIBLOC 5MG I.V INJECTION 100ML will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

AGGRIBLOC 5MG I.V INJECTION 100ML contains Tirofiban, an antiplatelet which prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. Also, it helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

How AGGRIBLOC 5MG I.V INJECTION 100ML Works

AGGRIBLOC 5MG I.V INJECTION 100ML contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Aggribloc 5mg I.v Injection 100ml
  • Apply an ice pack to slow bleeding and reduce swelling.
  • Keep your head raised to help blood drain away from your eye.
  • Take rest and avoid intense activities that raise pressure in the eye.
  • If the bleeding is severe or does not improve within 24 hours, consult a doctor.
  • Try to get 7-9 hours of sleep per night.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is cool, quiet and dark to maximize your sleep quality.
  • Get plenty of sunlight in the morning.
  • Do moderate-intensity exercises most days of the week and avoid strenuous exercise close to bedtime.
  • Limit processed foods and sugary drinks.
  • Avoid caffeine late in the day and drink in moderation in the morning.
  • Take short nap (20 to 30 minutes) mid-afternoon if required.

What if I have taken an overdose of AGGRIBLOC 5MG I.V INJECTION 100ML

Since AGGRIBLOC 5MG I.V INJECTION 100ML is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

If you are allergic to Tirofiban or any other medicines, please tell your doctor. AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML. Avoid alcohol consumption with AGGRIBLOC 5MG I.V INJECTION 100ML as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving AGGRIBLOC 5MG I.V INJECTION 100ML. If you have had cardiopulmonary resuscitation (CPR), a biopsy, or a procedure to break up kidney stones within the last 2 weeks or have been seriously injured, had a major operation or had an ulcer in the stomach or intestine within the last 3 months, had a recent spinal procedure, have history or symptoms of aortic dissection (splitting of the aorta, main artery), or had a special intravenous line inserted under your collar bone within the last 24 hours, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

Drug-Drug Interactions

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TirofibanClopidogrel
Severe
TirofibanDeferasirox
Severe

Drug-Drug Interactions

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TirofibanClopidogrel
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Taking Clopidogrel with Aggribloc 5mg I.v Injection 100ml can make the antiplatelet effects of Aggribloc 5mg I.v Injection 100ml stronger.

How to manage the interaction:
There may be a possibility of interaction between Aggribloc 5mg I.v Injection 100ml and Clopidogrel, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting your doctor.
TirofibanDeferasirox
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Using deferasirox together with Aggribloc 5mg I.v Injection 100ml may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Aggribloc 5mg I.v Injection 100ml with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
TirofibanFondaparinux
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Taking Aggribloc 5mg I.v Injection 100ml with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Fondaparinux and Aggribloc 5mg I.v Injection 100ml, it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TirofibanWarfarin
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Coadministration of warfarin with Aggribloc 5mg I.v Injection 100ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Aggribloc 5mg I.v Injection 100ml and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
TirofibanAspirin
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Using aspirin together with Aggribloc 5mg I.v Injection 100ml can cause you to bleed more easily.

How to manage the interaction:
Co-administration of Aspirin with Aggribloc 5mg I.v Injection 100ml can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, bruising, throwing up, headache, feeling dizzy, weakness, or seeing blood in your urine or stools. Do not stop using any medications without talking to a doctor.
TirofibanDasatinib
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Using dasatinib together with Aggribloc 5mg I.v Injection 100ml may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Aggribloc 5mg I.v Injection 100ml with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TirofibanIbrutinib
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Co-administration of Ibrutinib with Aggribloc 5mg I.v Injection 100ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Aggribloc 5mg I.v Injection 100ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
TirofibanRivaroxaban
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Co-administration of Aggribloc 5mg I.v Injection 100ml and Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Aggribloc 5mg I.v Injection 100ml and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TirofibanDalteparin
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Combining Aggribloc 5mg I.v Injection 100ml with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Aggribloc 5mg I.v Injection 100ml may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
TirofibanCangrelor
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Co-administration of Aggribloc 5mg I.v Injection 100ml with Cangrelor can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Aggribloc 5mg I.v Injection 100ml and Cangrelor, you can take these medicines together if prescribed by your doctor. However, consult doctor immediately if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor to avoid medication interactions.
  • Include foods high in antioxidants, such as vegetables, fruits, olive oil, seeds, nuts, cocoa, and red wine, as they may lower the risk of developing blood clots.
  • Adopt an anti-inflammatory diet high in omega-3-rich foods, fruits and vegetables, and vitamin E-rich foods.
  • Drink plenty of fluids as dehydration can thicken blood leading to an increased risk of blood clot formation.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid alcohol consumption as it may increase the risk of bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

AGGRIBLOC 5MG I.V INJECTION 100ML Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid the consumption of alcohol with AGGRIBLOC 5MG I.V INJECTION 100ML as it may increase the risk of bleeding in the stomach or intestines.

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Pregnancy

Consult your doctor

Limited data is available on the effect of AGGRIBLOC 5MG I.V INJECTION 100ML in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of AGGRIBLOC 5MG I.V INJECTION 100ML on breastfeeding mothers. Hence, if you are a nursing mother, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Due to your disease state, you will not be able to drive or operate machinery while receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

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Liver

Caution

AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended if you have severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

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Kidney

Caution

If you have kidney disease/condition, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML. The dose may be adjusted in patients with severe kidney failure.

bannner image

Children

Unsafe

AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

AGGRIBLOC 5MG I.V INJECTION 100ML is used to prevent blood clots, heart attack and chest pain.

AGGRIBLOC 5MG I.V INJECTION 100ML contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended for patients with severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

Yes, AGGRIBLOC 5MG I.V INJECTION 100ML may cause bleeding. If you notice blood in urine or stool or coughing up blood, please inform your doctor immediately, as these might be signs of internal bleeding.

While taking AGGRIBLOC 5MG I.V INJECTION 100ML, avoid medications such as NSAIDs (aspirin, ibuprofen), anticoagulants (heparin, warfarin), thrombolytic agents (streptokinase), other antiplatelet medicines (clopidogrel), and SSRIs (citalopram), as they may interact with AGGRIBLOC 5MG I.V INJECTION 100ML and cause negative complications. Always inform your doctor about your medication and health history for personalized guidance.

AGGRIBLOC 5MG I.V INJECTION 100ML is administered through an intravenous (IV) infusion by a healthcare professional.

You should avoid consuming alcohol while on AGGRIBLOC 5MG I.V INJECTION 100ML since it may raise the risk of bleeding in the stomach or intestines.

AGGRIBLOC 5MG I.V INJECTION 100ML gets to work quickly, and you may start feeling better within a few hours. As the medication rapidly prevents blood clots, you'll be on the road to recovery in no time. Follow your doctor's instructions and complete the full treatment course to ensure maximum benefits and a speedy return to health.

The common side effects of the AGGRIBLOC 5MG I.V INJECTION 100ML may include bleeding under the skin at the site of injection or into a muscle, causing swelling, bleeding after surgery, invisible blood in stool or urine, headache, or feeling sick. Most of these side effects of AGGRIBLOC 5MG I.V INJECTION 100ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - AGG0004

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:44 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5519.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/1998/20912lbl.pdf
  3. https://www.nps.org.au/assets/medicines/85512a05-d881-4dba-9e2b-a9c300a9d889.pdf
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