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Antigrain Tablet is indicated to treat and prevent migraine. It is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack. It narrows the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Also, it prevents nausea and vomiting associated with migraine. It may cause common side effects, such as stomach upset, dizziness, dry mouth, constipation, and insomnia (trouble sleeping).

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CAFFEINE-100MG+ERGOTAMINE-1MG+PARACETAMOL-250MG+PROCHLORPERAZINE-2.5MG

Manufacturer/Marketer :

Ikon Remedies Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Antigrain Tablet

Antigrain Tablet is a prescription oral medicine used to treat and manage acute migraine attacks, especially when accompanied by severe headache, nausea, and vomiting. This medicine is designed specifically to relieve symptoms during an active migraine attack rather than to prevent attacks from happening. It is important to take this medicine only when you feel a migraine starting, rather than on a daily schedule.

You can take Antigrain Tablet with or without food, swallow the tablet with a full glass of water. To achieve the best results, it is highly beneficial to combine this treatment with lifestyle changes, such as resting in a quiet, dark room and avoiding known migraine triggers. Because this medicine contains multiple active components, using it consistently only as directed by your healthcare provider is key to managing your symptoms safely.

While many patients tolerate this medicine well, some may experience common side effects such as drowsiness, dry mouth, or cold hands and feet. If you experience serious side effects like chest tightness, severe muscle pain in your legs, or numbness in your fingers and toes, you must contact your doctor immediately. Do not ignore these symptoms, as they require prompt medical evaluation.

Talk to your doctor before taking Antigrain Tablet if you have a history of high blood pressure, heart disease, liver disease, or kidney problems. Do not take this if you are pregnant, planning to become pregnant, or if you have peripheral vascular disease (poor blood circulation in your limbs). Your doctor will help determine if this is the safest treatment option for your specific health profile.

This medicine can interact with other substances, so it is crucial to discuss everything you take with your pharmacist or doctor. For example, smoking while taking this medicine increases the risk of severe blood vessel spasms, and drinking alcohol can increase drowsiness and the risk of liver damage. If you are breastfeeding or are an older adult, consult your doctor for tailored safety advice before using Antigrain Tablet.

Uses of Antigrain Tablet

Antigrain Tablet is used in the treatment of migraine. The detailed uses of Antigrain Tablet are as follows:

  • Acute Migraine Attacks: Antigrain Tablet helps to relieve the intense, throbbing headache pain associated with active migraine episodes.
  • Migraine-Associated Nausea: This medicine helps control the severe nausea and vomiting that frequently accompany migraine headaches.

Key Benefits

Antigrain Tablet helps relieve the symptoms of migraine attacks, allowing you to feel more comfortable and recover more quickly.

The following are the benefits of Antigrain Tablet:

  • Helps relieve moderate to severe migraine headache pain.
  • Reduces nausea and vomiting associated with migraine attacks.
  • Improves comfort by easing multiple migraine symptoms at the same time.
  • Supports better rest during a migraine episode.
  • Promotes a quicker return to normal daily activities.
  • Provides convenient relief with a combination of medicines in a single treatment.
Side effects of Antigrain Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Identify the medicine causing acidosis and talk to your doctor whether it can be discontinued or substituted with other medicine.
  • If you experience symptoms of acidosis like rapid breathing, confusion, overtiredness or nausea, contact your doctor immediately.
  • Your doctor may recommend dietary changes like changes in potassium intake based on the type of acidosis.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Take the tablet as soon as you feel the first signs of a migraine headache starting.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • If your symptoms do not improve, or if they return, talk to your doctor or pharmacist about how many tablets you can safely take in a 24-hour period.
  • Never exceed the maximum dose recommended by your healthcare provider.

How Antigrain Tablet Works

Antigrain Tablet combines four distinct active ingredients that work together to combat the symptoms of a migraine attack: • Ergotamine: This ingredient acts on certain brain and blood vessel receptors called serotonin receptors, which help narrow the widened blood vessels associated with a migraine and relieve the throbbing headache pain. • Caffeine: Caffeine increases the absorption of ergotamine in the body, allowing it to work more quickly and effectively, while also helping to constrict blood vessels. • Paracetamol: It is a well-known pain reliever and fever reducer. It lowers the production of prostaglandins (natural chemicals involved in pain and inflammation), mainly in the brain and spinal cord, helping reduce the intensity of the headache. • Prochlorperazine: This component blocks dopamine receptors in the brain to relieve severe nausea and vomiting, while also providing a mild calming effect to help you rest.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Antigrain Tablet as it may cause increased drowsiness.

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Pregnancy

Unsafe

Avoid taking Antigrain Tablet if you are pregnant or planning for pregnancy. Please consult your doctor if you are pregnant or if you have any concerns regarding this.

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Breast Feeding

Unsafe

Antigrain Tablet may pass into breastmilk. Avoid taking Antigrain Tablet if you are breastfeeding.

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Driving

Caution

Antigrain Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Antigrain Tablet should not be given to children as the safety and effectiveness were not established.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Antigrain Tablet can be given in elderly patients with extreme caution and only if prescribed by the doctor.

What if I have taken an overdose of Antigrain Tablet

If you take too much of this medicine, seek emergency medical attention or contact a poison control centre immediately. An overdose can cause serious complications, including severe blood vessel constriction and liver damage. Symptoms of an overdose may include severe vomiting, numbness in the extremities, extreme drowsiness, or confusion.

Diet & Lifestyle Advise

  • Track migraine triggers: Keep a migraine diary to record when your headaches occur, their symptoms, and possible triggers such as aged cheeses, artificial sweeteners, or skipped meals. This can help you identify patterns and avoid known triggers.
  • Maintain a regular sleep schedule: Go to bed and wake up at the same time every day, including weekends, to help reduce the risk of migraine attacks.
  • Stay well hydrated: Drink plenty of water throughout the day, as dehydration is a common trigger for migraines.
  • Rest in a calm environment: When a migraine begins, and you have taken your medicine, lie down in a quiet, dark room to help relieve symptoms and support recovery.
  • Limit caffeine intake: Reduce your intake of caffeinated drinks such as coffee, tea, and soda, as changes in caffeine consumption can trigger headaches in some people.
health query

Have a query?

How Soon It Starts Working

  • The time required for Antigrain Tablet to start to work: The time required for Antigrain Tablet to show its action is unknown.
  • The time for which the effects of Antigrain Tablet last: The duration of action for Antigrain Tablet is unknown.

What if you forget to take Antigrain Tablet

Since Antigrain Tablet is only taken when you are having an active migraine attack, there is no regular daily dosing schedule. If you miss a dose during an attack, take it as soon as you remember, but do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid frequent use: Do not take this medicine every day or for more than a few days unless your doctor advises you to. Overusing it can cause headaches to become more frequent or severe.
  • Avoid smoking and nicotine: Do not smoke or use nicotine products while taking this medicine. Nicotine can further narrow your blood vessels and increase the risk of side effects.
  • Do not take extra paracetamol: Check the labels of all your medicines and avoid taking other products that contain paracetamol. Taking too much paracetamol can seriously damage your liver.
  • Be careful when driving: Do not drive, ride a bicycle, or operate machinery until you know how this medicine affects you. It may cause drowsiness or dizziness.
  • Check before taking other medicines: Ask your doctor or pharmacist before using any over-the-counter cold, cough, or pain medicines. Some products may contain ingredients that can interact with this medicine.
  • Do not use for certain types of migraine: Avoid taking this medicine if you have hemiplegic migraine or migraine with brainstem aura. Ask your doctor if you are unsure what type of migraine you have.
  • Avoid during pregnancy: Do not take this medicine if you are pregnant or planning to become pregnant. Tell your doctor if you are pregnant, think you may be pregnant, or are planning a pregnancy before starting treatment.
  • Not usually for children: This medicine is generally not recommended for children or adolescents unless prescribed by a specialist. Your doctor will decide if it is suitable based on the child's age, medical condition, and treatment needs.

Drug-Drug Interactions

verifiedApollotooltip
  • Other migraine medicines (e.g., sumatriptan, dihydroergotamine): Do not take Antigrain Tablet within 24 hours of using triptans or other ergot-containing medicines, as this can cause dangerous narrowing of blood vessels.
  • Certain antibiotics and antifungals (e.g., erythromycin, ketoconazole): These medicines can slow down how your body breaks down the ergotamine component. This allows ergotamine to build up to higher levels in your blood, increasing the risk of serious side effects.
  • Heart medicines (e.g., atenolol, metoprolol): Taking these medicines alongside Antigrain Tablet can further reduce blood flow to your hands and feet.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineTelaprevir
Critical
Ergotamine + Caffeine + Paracetamol + ProchlorperazineProcarbazine
Critical

Drug-Drug Interactions

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Ergotamine + Caffeine + Paracetamol + ProchlorperazineTelaprevir
Critical
How does the drug interact with Antigrain Tablet:
Using ergotamine and Telaprevir together can increase the blood levels and effects of ergotamine.

How to manage the interaction:
Taking ergotamine and Telaprevir together is not recommended as it can lead to an interaction. However, if you experience any symptoms like severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineProcarbazine
Critical
How does the drug interact with Antigrain Tablet:
Using procarbazine together with ergotamine can increase the risk of a condition called the serotonin syndrome.

How to manage the interaction:
Taking procarbazine together with ergotamine is not recommended as it can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineAmprenavir
Critical
How does the drug interact with Antigrain Tablet:
Using ergotamine and amprenavir together can increase the blood levels and effects of ergotamine.

How to manage the interaction:
Using ergotamine and amprenavir together is not recommended as it can cause an interaction. However, if you experience any symptoms like severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineSumatriptan
Critical
How does the drug interact with Antigrain Tablet:
Using sumatriptan together with ergotamine can cause excessive narrowing of blood vessels in the body.

How to manage the interaction:
Taking Sumatriptan and Ergotamine is not recommended as it can lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor immediately. Do not discontinue any medication without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineDarunavir
Critical
How does the drug interact with Antigrain Tablet:
Using ergotamine and Darunavir together can increase the blood levels and effects of ergotamine.

How to manage the interaction:
Taking ergotamine and Darunavir together is not recommended as it can lead to an interaction. However, if you experience any symptoms like severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineLopinavir
Critical
How does the drug interact with Antigrain Tablet:
Using ergotamine and Lopinavir together can increase the blood levels and effects of ergotamine.

How to manage the interaction:
Taking ergotamine and Lopinavir together is not recommended as it can lead to an interaction. However, if you experience any symptoms like severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineNelfinavir
Critical
How does the drug interact with Antigrain Tablet:
Using ergotamine and Nelfinavir together can increase the blood levels and effects of ergotamine.

How to manage the interaction:
Taking ergotamine and Nelfinavir together is not recommended as it can lead to an interaction. However, if you experience any symptoms like severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineIsocarboxazid
Critical
How does the drug interact with Antigrain Tablet:
Using Ergotamine and Isocarboxazid can increase the risk of a condition called the serotonin syndrome.

How to manage the interaction:
Taking ergotamine with Isocarboxazid is not recommended as it can lead to an interaction, please consult your doctor before taking it. However, if you experience any symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineTranylcypromine
Critical
How does the drug interact with Antigrain Tablet:
Coadministration of tranylcypromine with Ergotamine can increase the risk of a rare but serious condition called the serotonin syndrome

How to manage the interaction:
Taking Ergotamine with Tranylcypromine is not recommended as it can lead to interaction. but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, Do not discontinue any medications without consulting a doctor.
Ergotamine + Caffeine + Paracetamol + ProchlorperazineSelegiline
Critical
How does the drug interact with Antigrain Tablet:
Using ergotamine and Selegiline together can increase the blood levels and effects of ergotamine.

How to manage the interaction:
Taking ergotamine and Selegiline together is not recommended as it can lead to an interaction. However, if you experience any symptoms like severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: Avoid consuming grapefruit or grapefruit juice, as it can interfere with how your body breaks down this medicine.
  • Alcohol: Avoid alcohol completely while using this medicine, as it increases drowsiness and raises the risk of liver damage.
CAFFEINE-100MG+ERGOTAMINE-1MG+PARACETAMOL-250MG+PROCHLORPERAZINE-2.5MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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CAFFEINE-100MG+ERGOTAMINE-1MG+PARACETAMOL-250MG+PROCHLORPERAZINE-2.5MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grape juice or grape fruit can increase the blood levels of ergotamine in the body. Consumption of grape juice increases the effect of caffeine. Limit your consumption of grapefruit and grapefruit juice during treatment with ergotamine and caffeine.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIMIGRAINE AGENTS]

FAQs

Antigrain Tablet is used to treat and prevent migraine. It is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack.
Antigrain Tablet contains Ergotamine, caffeine, prochlorperazine, and paracetamol. Ergotamine works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.
Dry mouth could be a side-effect of Antigrain Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Orthostatic hypotension could be a side-effect of Antigrain Tablet. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better.
Do not discontinue Antigrain Tablet without consulting your doctor as it could lead to recurring or worsening of symptoms. To treat your condition effectually, continue taking Antigrain Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Antigrain Tablet.
Do not take Antigrain Tablet along with antibiotics (clarithromycin, erythromycin, troleandomycin), antifungal (itraconazole, ketoconazole) and anti-HIV medicines (indinavir, nelfinavir, ritonavir). Antigrain Tablet contains ergotamine and caffeine, which, when taken along with these drugs, could lead to unpleasant side effects such as poor blood flow to the hands, feet, or brain.
Antigrain Tablet may cause constipation. Eat high-fibre foods and drink plenty of fluids if you experience constipation. Talk to your doctor if the condition persists or worsens.
When used responsibly and under medical guidance, Antigrain Tablet can be a highly effective treatment option. However, the long-term side effects are not well established. If you experience difficulties or concerns, consult your doctor promptly to discuss appropriate measures.
No, Antigrain Tablet is not a blood thinner. It is a medication used to treat migraine headaches and contains a combination of ergotamine, caffeine, paracetamol, and prochlorperazine.
No, taking a higher-than-recommended dose may not be more effective; instead, it may increase the risk of serious side effects and toxicity. Therefore, follow your doctor’s instructions and please consult your doctor. If you are experiencing increased severity of migraine attacks, which are not relieved by the recommended dose of this medicine, please consult your doctor for re-evaluation.
Yes, Antigrain Tablet can expire. Please check the expiration date on the medicine pack. Do not use the Antigrain Tablet after the expiry date.
A migraine is a severe headache that causes throbbing, pulsing pain on one side of the head. The headache phase usually lasts at least four hours, but it can also last for days.
Migraine attacks can be triggered by various factors, including hormonal changes (especially around menstruation), stress, lack of sleep or too much sleep, certain foods and drinks like alcohol, caffeine, aged cheeses, bright lights, loud noises, strong smells, weather changes, dehydration, and sudden physical exertion. However, each person may have unique triggers that vary depending on their sensitivity.
The common side effects of Antigrain Tablet are stomach upset, dizziness, dry mouth, constipation, and insomnia (trouble sleeping). Please consult your doctor if any of these side effects persist or worsen.
No, Antigrain Tablet is not designed for daily prevention. It should only be taken when you feel an active migraine attack starting. Using it too frequently can lead to daily rebound headaches. Talk to your doctor if you need preventive treatment.
Drowsiness is a common side effect of this medicine. If you feel sleepy or dizzy, lie down and rest in a safe place. Avoid driving, operating machinery, or performing any hazardous tasks until the feeling passes. Talk to your doctor if the sleepiness is severe.
It is best to limit your caffeine intake while taking this medicine. Because Antigrain Tablet already contains caffeine, consuming additional coffee, tea, or energy drinks can lead to jitters, a rapid heart rate, or sleep issues. Talk to your doctor or pharmacist about safe caffeine limits.
No, this medicine is not safe to take during pregnancy, as ergotamine can cause serious harm to an unborn baby. It is also not recommended while breastfeeding. If you are pregnant or nursing, talk to your doctor immediately about safer migraine treatment options.
Smoking introduces nicotine into your system, which naturally narrows your blood vessels. When combined with ergotamine, this can cause dangerously restricted blood flow to your extremities and organs. Talk to your doctor if you need help quitting smoking.
If your headache does not improve, do not take extra doses without consulting your doctor. Taking too much of this medicine can cause severe side effects. Talk to your doctor to see if a different dose or a different medicine is needed.
You should avoid taking other pain relievers, especially those containing paracetamol, while taking Antigrain Tablet. Doing so increases your risk of accidental liver damage. Always check with your pharmacist before combining any medications.
If you experience frequent migraines or need Antigrain Tablet often, talk to your doctor about preventive migraine treatment rather than relying only on medicines taken during an attack. Depending on your medical history, your doctor may recommend preventive options such as beta-blockers, topiramate, calcitonin gene-related peptide (CGRP)-targeting therapies, or other suitable medicines to help reduce how often migraines occur and improve long-term control.

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Country of origin

India
Other Info - AN78909
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