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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Antipreg Kit is used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. It also works in the second trimester of pregnancy. It contains Mifepristone and Misoprostol, which blocks the effects of the progesterone hormone required in women to continue the pregnancy. Also, it increases the womb's (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. In some cases, you may experience side effects such as nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Antipreg Kit

Antipreg Kit belongs to a group of gynaecological medications called ‘Abortifacient’ used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. Antipreg Kit also works in the second trimester of pregnancy.

Antipreg Kit contains two medicines, namely: Mifepristone and Misoprostol. Mifepristone is an anti-hormone (anti-progestogen) that blocks the effects of the progesterone hormone required in women to continue the pregnancy. On the other hand, Misoprostol is a prostaglandin that increases the womb’s (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. Thus, Antipreg Kit together cause termination of pregnancy and must be used one after the other for medical abortion.

A medical abortion generally involves 2-3 visits to a doctor or clinic, which includes giving medicines and then confirmation of termination of pregnancy. Following are the schedule involved in medical abortion:

  • Day 1: Medical counselling and examination where doctor instructs to take one tablet of mifepristone (200 mcg)

  • Day 2 to 3: You must return to the hospital/clinic 36 to 48 hours after taking the first dose of mifepristone. Your doctor will tell you about this. The tablet of Misoprostol (800 mcg) will now be given either orally or vaginally.

  • Day 7 to 14: The doctor will confirm and make sure whether the medical abortion has been completed or not. If the abortion is not complete, you might require more follow-up visits.

In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Antipreg Kit subside with time. But if vaginal bleeding does not stop, please visit the doctor immediately, as it requires immediate medical attention.

Antipreg Kit should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Antipreg Kit if you have had an ectopic pregnancy (when the womb grows in the fallopian tube), using an intrauterine device, or you are breastfeeding, any bleeding disorder or heart problem. Do not strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.

Uses of Antipreg Kit

Antipreg Kit is used for Medical abortion. The detailed uses of Antipreg Kit are as follows:
•Medical abortion: Antipreg Kit is generally used to terminate early pregnancies safely and successfully.
•Post-Surgery Procedure: It can be prescribed after gynecological surgeries to aid uterine healing, prevent problems, and speed up recovery.
•Regulating Menstrual Cycle: Antipreg Kit might help manage irregular menstrual cycles by inducing a period.
•Managing Ectopic Pregnancy: Antipreg Kit can also be used to manage ectopic pregnancies, which require particular care from a healthcare expert.

Directions for Use

Antipreg Kit should be taken in dose and duration as prescribed by your doctor.

Medicinal Benefits

Antipreg Kit contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone) needed to maintain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Antipreg Kit to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete. On the other hand, the second medicine is Misoprostol, a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Thus Together Antipreg Kit terminates the state of pregnancy. Misoprostol should be taken at least 24-36 hours after taking mifepristone, either orally or vaginally. This is a non-surgical method which is 90% successful.

How Antipreg Kit Works

Antipreg Kit contains two medicines, namely: Mifepristone and Misoprostol. Mifepristone is an anti-hormone (anti-progestogen) that blocks the effects of the progesterone hormone required in women to continue the pregnancy. On the other hand, Misoprostol is a prostaglandin that increases the womb’s (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. Thus, Antipreg Kit together cause termination of pregnancy and must be used one after the other for medical abortion.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Antipreg Kit

Do not take more than the prescribed dose of Antipreg Kit as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Antipreg Kit if you are allergic to misoprostol and mifepristone, have a heart fitted with an artificial valve, have heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Antipreg Kit in these conditions can cause life-threatening conditions in an individual. Antipreg Kit is known to cause sleepiness, so driving or operating machinery should not be done. If you use contraceptive devices like the intrauterine device (IUD), please remove it before taking Antipreg Kit. Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (a natural remedy used to treat mild depression) grapefruit juice should not be taken when taking Antipreg Kit as it is known to interact.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Antipreg Kit:
When Methylprednisolone is taken with Antipreg Kit, it may decrease the levels of Methylprednisolone, which may be less effective in treating your condition.

How to manage the interaction:
Taking Methylprednisolone with Antipreg Kit is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Antipreg Kit:
Co-administration of Betamethasone with Antipreg Kit may significantly reduce the effect of Betamethasone which may be less effective as a therapy.

How to manage the interaction:
Taking betamethasone with Antipreg Kit together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Antipreg Kit:
Co-administration of Antipreg Kit with Ticagrelor can increase the risk of vaginal bleeding in women.

How to manage the interaction:
Taking Ticagrelor with Antipreg Kit is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any symptoms like heavy period bleed for more than 7 days, weakness, tiredness, shortness of breath or paleness. Do not discontinue any medications without consulting a doctor.
MifepristoneFluticasone Propionate
Critical
How does the drug interact with Antipreg Kit:
Co-administration of Fluticasone Propionate with Antipreg Kit can increase the risk of side effects.

How to manage the interaction:
Taking Antipreg Kit and Fluticasone Propionate is not recommended, but can be taken if prescribed by a doctor. Do no discontinue any medications without consulting a doctor.
How does the drug interact with Antipreg Kit:
Using Fluticasone furoate with Antipreg Kit can reduce the effect of fluticasone furoate.

How to manage the interaction:
Taking Fluticasone furoate with Antipreg Kit is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Antipreg Kit:
Combining Antipreg Kit with Enoxaparin can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Enoxaparin with Antipreg Kit is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Antipreg Kit:
Using Antipreg Kit together with budesonide may significantly reduce the effects of budesonide.

How to manage the interaction:
Taking Budesonide with Antipreg Kit is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Antipreg Kit:
When Antipreg Kit is taken with Dabigatran etexilate, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Antipreg Kit with Dabigatran etexilate is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Antipreg Kit:
Combining Antipreg Kit with Simvastatin can increase the blood levels of simvastatin, which may increase the risk of side effects.

How to manage the interaction:
Taking Simvastatin with Antipreg Kit is not recommended, but can be taken if prescribed by the doctor. If you experience any symptoms, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Antipreg Kit:
Coadministration of Sirolimus with Antipreg Kit can increase the levels of Sirolimus in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Sirolimus with Antipreg Kit is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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MIFEPRISTONE-200MG+MISOPROSTOL-200MCGFruit juices, Fruits
Moderate

Drug-Food Interactions

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MIFEPRISTONE-200MG+MISOPROSTOL-200MCGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or grapefruit juice along with Antipreg Kit may cause the medication's blood levels to rise to unwanted levels and raise the chance of adverse effects. Avoid taking grapefruit or grapefruit juice along with Antipreg Kit as this can raise the chance of adverse effects. However, consult a doctor if you experience headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, hypokalemia (low blood potassium), fluid retention, swelling, and high blood pressure.

Diet & Lifestyle Advise

  • Keep your weight under control with body mass index (BMI) 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Quitting smoking and not drinking alcohol is the best strategy to lower the risk of any complication.
  • Avoid chronic stress and physical exercise like running as it might increase vaginal bleeding.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Get an ultrasound done to check if the abortion is done completely to avoid any unwanted complications.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ABORTIFACIENT, CERVICAL RIPENING AGENTS
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Alcohol

Unsafe

Alcohol is known to cause excessive drowsiness and increases uterine bleeding if taken along with Antipreg Kit.

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Pregnancy

Unsafe

Antipreg Kit is used for medical abortion. If taken in pregnancy, it can lead to abortion.

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Breast Feeding

Unsafe

Antipreg Kit should not be taken if breastfeeding as it may pass through the milk to the baby.

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Driving

Unsafe

Driving is unsafe when taking Antipreg Kit as it might increase the risk of excessive bleeding.

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Liver

Caution

Antipreg Kit to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Antipreg Kit to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Antipreg Kit is not recommended for children below the age of 12. The safety and effectiveness of Antipreg Kit have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Antipreg Kit or not.

Have a query?

FAQs

Antipreg Kit is used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. Antipreg Kit also works in the second trimester of pregnancy.

Antipreg Kit contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. Misoprostol is a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Misoprostol should be taken 24-36 hours after taking mifepristone, either orally or vaginally.

No, Antipreg Kit should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine or vaginal bleeding.

No, Antipreg Kit is not known to affect any future chances of pregnancy. Antipreg Kit is used for medical abortion of early or unwanted pregnancy.

After taking Antipreg Kit, you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.

Do not take Antipreg Kit, if you have a heart fitted with an artificial valve, heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Antipreg Kit in these conditions can cause life-threatening conditions in an individual.

Antipreg Kit does not decrease the chances of survival of your future pregnancy. It is specifically used for the present medical abortion of an early or unwanted pregnancy and does not affect future pregnancies. They will not impact your ability to carry a healthy pregnancy in the future.

Antipreg Kit is a combination of two medicines: Mifepristone and Misoprostol, which belong to a group of gynaecological medications called Abortifacient. Used for medical abortion to terminate an early or unwanted pregnancy.

Store Antipreg Kit in a cool, dry place away from sunlight. Keep it out of reach of children.

Antipreg Kit may cause interaction with certain medications, including corticosteroids, antifungals, antibiotics, anti-epileptics, immunosuppressants, and migraine medications. Taking Antipreg Kit with these medications may cause negative complications. It's essential to inform your doctor about all medications and health histories you are taking, and they will assess your condition and help manage it to avoid complications.

You should take Antipreg Kit exactly as directed by your doctor. Your doctor will determine the dose and duration based on your pregnancy status, menstrual cycle, medical history, and especially sexual intimation time history. Follow your doctor's instructions carefully and complete the full course as prescribed for a safe and healthy abortion process.

The common side effects of Antipreg Kit may include nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Antipreg Kit subside with time. If these symptoms become worse, please consult a doctor for relief.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ANT0098

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