Cadila Pharmaceuticals Ltd
MIFEPRISTONE-200MG + MISOPROSTOL-200MCG
Mifegest Kit belongs to a group of gynaecological medications called ‘Abortifacient’ used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. Mifegest Kit also works in the second trimester of pregnancy.
Mifegest Kit contains two medicines, namely: Mifepristone and Misoprostol. Mifepristone is an anti-hormone (anti-progestogen) that blocks the effects of the progesterone hormone required in women to continue the pregnancy. On the other hand, Misoprostol is a prostaglandin that increases the womb’s (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. Thus, Mifegest Kit together cause termination of pregnancy and must be used one after the other for medical abortion.
A medical abortion generally involves 2-3 visits to a doctor or clinic, which includes giving medicines and then confirmation of termination of pregnancy. Following are the schedule involved in medical abortion:
In some cases, you may experience nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Most of these side effects of Mifegest Kit subside with time. But if vaginal bleeding does not stop, please visit the doctor immediately, as it requires immediate medical attention.
Mifegest Kit should not be stopped abruptly without consulting the doctor as it may lead to incomplete abortion. Inform your doctor before starting Mifegest Kit if you have had an ectopic pregnancy (when the womb grows in the fallopian tube), using an intrauterine device, or you are breastfeeding, any bleeding disorder or heart problem. Do not strenuous activities like running, heavy exercise, or driving to avoid excessive bleeding. The doctor will also check with ultrasound if the absorption is complete as no bleeding does not mean that abortion is complete.
Mifegest Kit contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone) needed to maintain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. It takes approximately 24-48 hours for Mifegest Kit to show effect. Once it starts acting, you will experience uterine bleeding. But no uterine bleeding does not mean that the abortion is complete. On the other hand, the second medicine is Misoprostol, a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Thus Together Mifegest Kit terminates the state of pregnancy. Misoprostol should be taken at least 24-36 hours after taking mifepristone, either orally or vaginally. This is a non-surgical method which is 90% successful.
Do not take Mifegest Kit if you are allergic to misoprostol and mifepristone, have a heart fitted with an artificial valve, have heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Mifegest Kit in these conditions can cause life-threatening conditions in an individual. Mifegest Kit is known to cause sleepiness, so driving or operating machinery should not be done. If you use contraceptive devices like the intrauterine device (IUD), please remove it before taking Mifegest Kit. Regular follow-up with the doctor is required for constant monitoring of abortion. If medical termination does not happen or becomes unsuccessful, it should be terminated surgically as it can lead to foetal defects. Your doctor will examine by performing ultrasonography to confirm if the abortion is complete. St John’s Wort (a natural remedy used to treat mild depression) grapefruit juice should not be taken when taking Mifegest Kit as it is known to interact.
Drug-Drug Interactions: Mifegest Kit interacts with corticosteroids (dexamethasone), antifungal (ketoconazole, itraconazole), antibiotics (erythromycin, rifampicin), anti-epileptic (phenytoin, phenobarbital, carbamazepine), immunosuppressants (cyclosporine, tacrolimus, sirolimus), medicines to treat migraine (ergotamine). So, Mifegest Kit should not be taken along with these drugs.
Drug-Food Interactions: Please tell your doctor about all the Vitamins, herbs, and supplements you are taking as Mifegest Kit may interact with them to produce unpleasant side effects. Also, Mifegest Kit is known to interact with St John’s Wort (a natural remedy used to treat mild depression), and grapefruit juice.
Drug-Disease Interactions: Mifegest Kit should be taken with caution in people who have a bleeding problem, confirmed or suspected ectopic pregnancy, heart problem, liver or kidney disease, vaginal bleeding, porphyria (an inherited blood disease that may cause nervous system or skin problems).
Alcohol is known to cause excessive drowsiness and increases uterine bleeding if taken along with Mifegest Kit.
Mifegest Kit is used for medical abortion. If taken in pregnancy, it can lead to abortion.
Mifegest Kit should not be taken if breastfeeding as it may pass through the milk to the baby.
Driving is unsafe when taking Mifegest Kit as it might increase the risk of excessive bleeding.
Mifegest Kit to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Mifegest Kit to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
This item is Not Returnable.
Expires on or after - Mar-23
Medical abortion: It is a procedure in which medicine is used to terminate a pregnancy. It is effectively causing abortion if performed in the first 70 days of pregnancy. Vagina bleeding occurs, and if it does not stop, please inform your doctor as it might require medical supervision. Having a medical abortion is a very emotional decision. You should be mentally prepared for all the risks a surgical absorption could lead to, like incomplete abortion, heavy and prolonged bleeding (may last up to 30 days), fever, digestive system discomfort fever. Also, if the medication does not work, it can lead to an unwanted ongoing pregnancy, leading to fetal defects. So, to avoid any complications, keep in regular touch with your doctor and do as advised.
Mifegest Kit contains Mifepristone and Misoprostol. Mifepristone works by blocking the effect of progesterone (female hormone), which is needed to sustain a pregnancy. In the absence of progesterone, the lining of the uterus breaks down as it does every month during the menstrual cycle, and the growth of pregnancy is stopped. Misoprostol is a prostaglandin analogue that helps increase uterine contractions and relaxes the cervix. Misoprostol should be taken 24-36 hours after taking mifepristone, either orally or vaginally.
No, Mifegest Kit should be taken in the dose and duration as advised by the doctor. Taking it in more than the recommended dose might cause unpleasant side effects like excessive uterine or vaginal bleeding.
No, Mifegest Kit is not known to affect any future chances of pregnancy. Mifegest Kit is used for medical abortion of early or unwanted pregnancy.
After taking Mifegest Kit, you may or may not experience vaginal bleeding, which does not indicate complete abortion. Your doctor will examine with the performing ultrasonography to confirm if the abortion is complete.
Do not take Mifegest Kit, if you have a heart fitted with an artificial valve, heart diseases like high blood pressure or high blood cholesterol levels (increased fat in your blood), have asthma, have blood clot problems, have a bleeding disorder, have liver or kidney disease, have anaemia (low haemoglobin) or otherwise malnourished. Taking Mifegest Kit in these conditions can cause life-threatening conditions in an individual.
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