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  3. Apiz-MD 5 Tablet 10's

Apiz-MD 5 Tablet 10's, Pack of 10 TabletS
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Apiz-MD 5 Tablet is an atypical antipsychotic medicine used to treat various mood disorders, including schizophrenia, acute manic and mixed episodes associated with Bipolar I disorder, irritability related to autism spectrum disorder, Tourette’s disorder, and as an add-on (adjunctive) treatment for major depressive disorder (MDD). Apiz-MD 5 Tablet contains Aripiprazole, which works by restoring the balance of dopamine and serotonin in the brain that influences mood, behaviour, and thinking. By doing so, it helps relieve symptoms of various mood and behavioural disorders. Common side effects of Apiz-MD 5 Tablet in adults may include nausea, dizziness, vomiting, anxiety, constipation, trouble sleeping, headache, restlessness, blurred vision, and cold-like symptoms. In children, common side effects can include sleepiness, insomnia, headache, nausea, vomiting, nasal congestion, tiredness, weight changes, changes in appetite, restlessness, tremors, drooling, and muscle stiffness. Most side effects are mild and go away over time, but consult your doctor if they persist or worsen.

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Composition :

ARIPIPRAZOLE-5MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Apiz-MD 5 Tablet

Apiz-MD 5 Tablet is an atypical antipsychotic medicine used to treat several mental health conditions, including schizophrenia, acute manic and mixed episodes associated with Bipolar I disorder, irritability related to autism spectrum disorder, Tourette’s disorder, and as an add-on (adjunctive) treatment for major depressive disorder (MDD). These conditions can affect mood, behaviours, and thinking and may significantly impact daily functioning and relationships.

Apiz-MD 5 Tablet contains Aripiprazole, which works by restoring the balance of dopamine and serotonin in the brain—chemicals that influence mood, behaviour, and thinking. By doing so, it helps relieve symptoms of various mood and behavioural disorders.

Common side effects in adults may include nausea, dizziness, vomiting, anxiety, constipation, trouble sleeping, headache, restlessness, blurred vision, and cold-like symptoms. In children, common side effects can include sleepiness, insomnia, headache, nausea, vomiting, nasal congestion, tiredness, weight changes, changes in appetite, restlessness, tremors, drooling, and muscle stiffness. Most side effects are mild and go away over time, but consult your doctor if they persist or worsen.

Apiz-MD 5 Tablet should not be used in individuals allergic to Aripiprazole or elderly patients with dementia-related psychosis due to an increased risk of death. Serious risks may include suicidal thoughts or behaviours (especially in young people), neuroleptic malignant syndrome (a rare but life-threatening condition), and involuntary movements like tardive dyskinesia. Other potential concerns include dizziness, drowsiness, seizures, high blood sugar, weight gain, low blood pressure, and impulse-control problems such as compulsive gambling. Use during the third trimester of pregnancy may cause movement or withdrawal symptoms in newborns. If breastfeeding, your doctor may recommend stopping the medicine or breastfeeding, depending on what’s best for your health. Do not drive, operate heavy machinery, or do other dangerous activities until you know how Apiz-MD 5 Tablet affects you. Apiz-MD 5 Tablet may usually cause drowsiness, sleepiness, and restlessness.

Uses of Apiz-MD 5 Tablet

Apiz-MD 5 Tablet is primarily used in the treatment of various mental or mood disorders. Detailed uses are as follows: <br/>• Schizophrenia – to help manage symptoms such as hallucinations, disorganised thinking, and emotional withdrawal. <br/>• Acute treatment of manic and mixed episodes associated with Bipolar I disorder – to stabilise mood during sudden episodes of elevated or mixed emotions. <br/>• Adjunctive treatment of Major Depressive Disorder (MDD) – used along with antidepressants to improve symptoms of persistent sadness or low mood. <br/>• Irritability associated with Autistic Disorder – to reduce symptoms such as aggression, temper tantrums, and mood swings in children with autism. <br/>• Tourette’s disorder – to help control involuntary movements and vocal tics.

Directions for Use

  • Apiz-MD 5 Tablet can be taken with or without food, as advised by the doctor.
  • It is usually taken once daily or as prescribed by your doctor.
  • Place Apiz-MD 5 Tablet in your mouth and allow it to dissolve completely before swallowing.
  • Do not crush, chew, or swallow it as a whole.

Medicinal Benefits

Apiz-MD 5 Tablet contains Aripiprazole, an atypical antipsychotic that works by balancing dopamine and serotonin levels in the brain, chemicals that influence mood, behaviour, and thinking. By restoring this balance, it helps reduce symptoms such as hallucinations, mood swings, irritability, and depressive thoughts. As a result, Apiz-MD 5 Tablet is beneficial in managing conditions like schizophrenia, acute manic and mixed episodes in Bipolar I disorder, major depressive disorder (when used with antidepressants), irritability associated with autism, and involuntary tics in Tourette’s disorder. It helps improve emotional stability, daily functioning, and overall quality of life in people affected by these mental health conditions.

How Apiz-MD 5 Tablet Works

Apiz-MD 5 Tablet contains Aripiprazole, which works by restoring the balance of dopamine and serotonin in the brain—chemicals that influence mood, behaviour, and thinking. By doing so, it helps relieve symptoms of various mood and behavioural disorders.

Storage

• Store in a cool and dry place away from sunlight.• Keep Apiz-MD 5 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Apiz-MD 5 Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

What if I have taken an overdose of Apiz-MD 5 Tablet

Do not take more than the prescribed dose of Apiz-MD 5 Tablet , as it may cause an overdose. Symptoms of an overdose may include confusion, tremors, drowsiness, vomiting, aggression, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Apiz-MD 5 Tablet should not be used in individuals with a known allergy to the drug or elderly patients with dementia-related psychosis due to an increased risk of death. Serious side effects may include suicidal thoughts or behaviours (particularly in children, adolescents, and young adults), neuroleptic malignant syndrome (a rare but life-threatening condition), and tardive dyskinesia (involuntary movements). The medication may also cause dizziness, sleepiness, seizures, and low blood pressure, which could increase the risk of falls. Other risks include high blood sugar, weight gain, low white blood cell count, difficulty swallowing, and impulse-control issues such as compulsive gambling. Aripiprazole can impair judgment, motor skills, and the body’s ability to regulate temperature, so patients should avoid driving if affected and stay well hydrated in hot weather. It may interact with other medications, especially those affecting liver enzymes (CYP2D6 and CYP3A4) or blood pressure, so it’s essential to inform your doctor of all medicines being taken. Regular monitoring of blood sugar, weight, and blood counts may be recommended during treatment to ensure optimal health and well-being. Use during the third trimester of pregnancy may cause movement or withdrawal symptoms in newborns. If breastfeeding, your doctor may recommend stopping the medicine or breastfeeding, depending on what’s best for your health.

Drug-Drug Interactions

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AripiprazoleMetoclopramide
Critical
AripiprazoleOxycodone
Severe

Drug-Drug Interactions

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AripiprazoleMetoclopramide
Critical
How does the drug interact with Apiz-MD 5 Tablet:
Co-administration of Metoclopramide with Apiz-MD 5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Apiz-MD 5 Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AripiprazoleOxycodone
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Using Apiz-MD 5 Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Apiz-MD 5 Tablet with Oxycodone together can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleButorphanol
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Using Apiz-MD 5 Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Apiz-MD 5 Tablet with Butorphanol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend other options that won't cause any problems. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleHydrocodone
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Using Apiz-MD 5 Tablet together with Hydrocodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Apiz-MD 5 Tablet and Hydrocodone together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like trouble breathing, feeling very sleepy, or having trouble focusing, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
AripiprazoleEsketamine
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Using Esketamine together with Apiz-MD 5 Tablet may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Taking Apiz-MD 5 Tablet with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like feeling sleepy, having trouble concentrating, or feeling confused, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without talking to a doctor.
AripiprazoleDezocine
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Using Apiz-MD 5 Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Apiz-MD 5 Tablet with Dezocine together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
AripiprazoleBupropion
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Taking bupropion with Apiz-MD 5 Tablet may raise the chance of seizures (fits), which can happen with either medicine. Furthermore, bupropion can raise Apiz-MD 5 Tablet levels in the blood, which may increase other side effects.

How to manage the interaction:
Co-administration of bupropion along with Apiz-MD 5 Tablet can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
AripiprazoleIohexol
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Apiz-MD 5 Tablet and Iohexol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Apiz-MD 5 Tablet and Iohexol together can cause an interaction, it can be taken if a doctor has suggested it. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.
AripiprazoleTetrabenazine
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Combining Apiz-MD 5 Tablet with Tetrabenazine can increase the risk of side effects.

How to manage the interaction:
Taking Apiz-MD 5 Tablet with Tetrabenazine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleHydromorphone
Severe
How does the drug interact with Apiz-MD 5 Tablet:
Using Apiz-MD 5 Tablet together with Hydromorphone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Apiz-MD 5 Tablet and Hydromorphone together can cause an interaction, it can be taken if a doctor has suggested it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Balanced Nutrition and Lifestyle Choices Can Positively Influence Mental Health.
  • Eat a nutrient-rich diet: Include vegetables, fruits, whole grains, and lean proteins to support brain function and emotional balance. Include omega-3 fatty acids found in fish (such as salmon), flaxseeds, and walnuts, which may help reduce symptoms of depression and mood swings.
  • Avoid highly processed and sugary foods: They can lead to blood sugar crashes and may negatively affect mood.
  • Stay hydrated: Dehydration can affect energy levels, concentration, and mood stability.
  • Maintain consistent meal times – Regular eating patterns help stabilise blood sugar and support emotional regulation.
  • Exercise regularly: Even 30 minutes of moderate activity daily can help boost your mood and reduce anxiety by increasing natural brain chemicals, such as endorphins.
  • Get quality sleep: Aim for 7–9 hours of restful sleep; poor sleep can worsen symptoms of mood disorders.
  • Practice stress-reducing activities – Techniques like mindfulness, yoga, or journaling can help manage emotional stress.
  • Build a strong support system – Regular social interaction and emotional support from friends, family, or therapy can improve mental well-being.
  • Avoid alcohol and drug use: These substances can interfere with mood stability and increase the risk of depression and anxiety.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Apiz-MD 5 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while taking Apiz-MD 5 Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.

bannner image

Pregnancy

Unsafe

It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.

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Breast Feeding

Consult your doctor

Your doctor may recommend stopping the medicine or breastfeeding, depending on what’s best for your health.

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Driving

Unsafe

It is recommended not to drive or operate machinery while taking this medication, as it may affect your ability to do so safely.

bannner image

Liver

Caution

Take Apiz-MD 5 Tablet with caution if you have a history of liver disease. Your doctor may adjust the dose and monitor your condition if needed. Always inform your doctor about any existing health issues before starting the medication.

bannner image

Kidney

Caution

Take Apiz-MD 5 Tablet with caution if you have a history of kidney disease. Your doctor may adjust the dose and monitor your condition if needed. Always inform your doctor about any existing health issues before starting the medication.

bannner image

Children

Consult your doctor

There is limited information on the use of Apiz-MD 5 Tablet in pediatric patients. Please consult your doctor, who will prescribe it only if the potential benefits outweigh the risks.

Have a query?

FAQs

Apiz-MD 5 Tablet contains Aripiprazole. It is used to treat mental health conditions like schizophrenia, mood changes in Bipolar I disorder, depression (with other medicines), irritability in children with autism, and Tourette’s disorder. It works by helping to balance natural brain chemicals, thereby improving mood, behaviour, and thinking.

Apiz-MD 5 Tablet contains Aripiprazole, an antipsychotic medication that works by helping to balance natural brain chemicals, thereby improving mood, behaviour, and thinking.

No, you are not recommended to take Apiz-MD 5 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Apiz-MD 5 Tablet in the blood, leading to increased adverse effects. So, please consult a doctor before taking Apiz-MD 5 Tablet with other medicines.

Yes, Apiz-MD 5 Tablet may cause weight gain in some people, especially in children and adolescents. However, the risk is generally lower compared to some other antipsychotic medicines. Regular monitoring of weight, diet, and physical activity is recommended during treatment. If you notice significant weight changes, it's best to consult your doctor.

Apiz-MD 5 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Apiz-MD 5 Tablet .

Yes, Apiz-MD 5 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Apiz-MD 5 Tablet and inform your doctor if you have diabetes before taking Apiz-MD 5 Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.

No, you are not recommended to stop taking Apiz-MD 5 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Apiz-MD 5 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Apiz-MD 5 Tablet , please consult your doctor so that the dose may be gradually reduced.

Yes, Apiz-MD 5 Tablet is a mood stabilizer. It helps calm the mood and treats mood-related problems.

Apiz-MD 5 Tablet might start working within a few days or weeks. However, you may notice the full benefits of Apiz-MD 5 Tablet after 2-3 months. Continue taking Apiz-MD 5 Tablet for the prescribed duration to prevent the recurrence of symptoms.

Apiz-MD 5 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.

You should know that Apiz-MD 5 Tablet is used to treat certain mental health conditions and must be taken exactly as prescribed at the correct dose and time each day. It's also essential to understand its limitations, such as who should not use it (e.g., people allergic to it or elderly patients with dementia-related psychosis) and the risk of serious side effects like suicidal thoughts, unusual movements, or changes in blood sugar. Always follow your doctor's advice and report any concerns you may have during treatment.

While using Apiz-MD 5 Tablet , avoid drinking alcohol, as it may increase drowsiness or dizziness. Be careful when driving or using machines if you feel sleepy or less alert. Stay cool and hydrated, especially in hot weather, as the medicine can affect how your body regulates its temperature. Do not take any other medication or make changes to your diet or lifestyle without your doctor’s advice, as these may affect how the medicine works or increase side effects.

Apiz-MD 5 Tablet can be taken by people with diabetes, but caution is needed. This medication may increase blood sugar levels, so people with diabetes should monitor their blood sugar regularly during treatment. It’s essential to inform your doctor about your diabetes before starting Apiz-MD 5 Tablet so they can adjust your treatment plan if necessary and monitor for any changes.

Common side effects of Apiz-MD 5 Tablet include nausea, dizziness, vomiting, anxiety, trouble sleeping, headache, and restlessness in adults. In children, it may cause sleepiness, nausea, changes in appetite or weight, drooling, and muscle stiffness. Most side effects are mild and go away on their own, but let your doctor know if they continue or get worse.

Country of origin

India

Manufacturer/Marketer address

Reliance Formulation Private Limited, 201-202, Anand Mangal-3, Rajnagar Club Road Ambabadi, Ahmedabad-380015, Gujarat, India
Other Info - API0164

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Reference

  1. https://www.drugs.com/aripiprazole.html
  2. https://www.medicines.org.uk/emc/files/pil.14207.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021436s038,021713s030,021729s022,021866s023lbl.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/202102s000lbl.pdf
  5. https://www.medicines.org.uk/emc/files/pil.11122.pdf
  6. https://registrasiobat.pom.go.id/files/assesment-reports/01701929229.pdf

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