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  3. Aplet 5mg Tablet 10's

Aplet 5mg Tablet 10's, Pack of 10 TABLETS
Aplet 5mg Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Aplet 5mg Tablet is used to prevent the formation of blood clots, thereby reducing the chance of having a heart attack or stroke in future. It is prescribed after a heart attack, unstable angina, or if you have been treated with a procedure to open blocked arteries or have stents to open blocked/narrowed arteries. It contains Prasugrel, which works by inhibiting the clumping of platelets, thereby reducing the chance of having blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or stroke in future, especially in people who have had heart surgery known as angioplasty. In some cases, it may cause side effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, purpura (blood leakage under the skin), indigestion and bruising.
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Composition :

PRASUGREL-5MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Aplet 5mg Tablet

Aplet 5mg Tablet belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of having a heart attack or stroke in future. Aplet 5mg Tablet is prescribed after a heart attack, unstable angina, or if you have been treated with a procedure to open blocked arteries or have stents to open blocked/narrowed arteries. 

Aplet 5mg Tablet contains 'Prasugrel' which works by inhibiting the clumping of platelets, thereby reducing the chance of having blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or stroke in future, especially in people who have had heart surgery known as angioplasty.

You are advised to take Aplet 5mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, Aplet 5mg Tablet may cause side effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, purpura (blood leakage under the skin), indigestion and bruising. You are advised to talk to your doctor if you experience these side effects persistently.

Do not take Aplet 5mg Tablet if you ever had a brain stroke, bleeding in the brain or transient ischemic attack (stroke). Talk to your doctor before taking Aplet 5mg Tablet if you weigh below 60 kg, are 75 years or older, and have/had a recent severe injury or surgery due to the risk of severe bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Aplet 5mg Tablet is not recommended for children as efficacy and safety have not been established. 

Uses of Aplet 5mg Tablet

Treatment of Prevention of Blood clot, Prevention of Heart attack, Prevention of Stroke.

Directions for Use

Swallow Aplet 5mg Tablet as a whole with a glass of water. Do not crush, break or chew it.

Medicinal Benefits

Aplet 5mg Tablet belongs to the group of medicines called antiplatelet agents used to prevent the formation of blood clots. Aplet 5mg Tablet helps in reducing the chance of having another heart attack or stroke. Aplet 5mg Tablet inhibits platelet aggregation and activation through irreversible binding of its active metabolite to the receptors. Aplet 5mg Tablet works by inhibiting the clumping of platelets, thereby reduces the chance of blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke especially in people who have had heart surgery known as angioplasty.

How Aplet 5mg Tablet Works

Aplet 5mg Tablet contains 'Prasugrel' which works by inhibiting the clumping of platelets, thereby reducing the chance of having blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or stroke in future, especially in people who have had heart surgery known as angioplasty.

Storage

Store in a cool and dry place away from sunlight
Side effects of Aplet 5mg Tablet
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Aplet 5mg Tablet

Do not take more than the prescribed dose of Aplet 5mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Aplet 5mg Tablet if you are allergic to any of its contents, if you have a medical condition that causes bleeding from the stomach or intestine, had a transient ischemic attack (stroke) or if you are suffering from severe liver disease. Talk to your doctor before taking Aplet 5mg Tablet if you have bleeding problems, weigh below 60 kg, are 75 years or older, had/have a recent serious injury or surgery, kidney or liver disease. Consult your doctor immediately if you develop a medical condition called thrombotic thrombocytopenic purpura (blood disorder) while taking Aplet 5mg Tablet ; its symptoms include fever, bruising under the skin which appears as red pinpoint dots, with/without unexplained confusion, tiredness and yellowing of skin and eyes. Consult your doctor if you are pregnant or breastfeeding. Aplet 5mg Tablet is not recommended for children as the efficacy and safety have not been established. People affected with active pathological bleeding (peptic ulcer, intracranial or brain haemorrhage) and history of stroke or transient ischemic attack (TIA) should not take Aplet 5mg Tablet .

Drug-Drug Interactions

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PrasugrelMifepristone
Critical
PrasugrelDalteparin
Severe

Drug-Drug Interactions

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PrasugrelMifepristone
Critical
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Mifepristone with Aplet 5mg Tablet can increase the chance of experiencing vaginal bleeding in women.

How to manage the interaction:
Taking Aplet 5mg Tablet with Mifepristone can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience prolonged, heavy bleeding, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.
PrasugrelDalteparin
Severe
How does the drug interact with Aplet 5mg Tablet:
Combining Aplet 5mg Tablet with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Aplet 5mg Tablet with Defibrotide may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
PrasugrelPlicamycin
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Aplet 5mg Tablet with Plicamycin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Aplet 5mg Tablet with Plicamycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelApixaban
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Apixaban with Aplet 5mg Tablet can lower the levels of Apixaban which can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Apixaban with Aplet 5mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PrasugrelBivalirudin
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Aplet 5mg Tablet with Bivalirudin can increase the risk of bleeding.

How to manage the interaction:
Although taking Aplet 5mg Tablet and Bivalirudin together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelTirofiban
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Tirofiban with Aplet 5mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Tirofiban and Aplet 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelStreptokinase
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Aplet 5mg Tablet with Streptokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Streptokinase with Aplet 5mg Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelIbritumomab tiuxetan (90y)
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Aplet 5mg Tablet with Ibritumomab tiuxetan (90y) can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Co-administration of Aplet 5mg Tablet with Ibritumomab tiuxetan (90y) can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelWarfarin
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Warfarin with Aplet 5mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Although taking Aplet 5mg Tablet and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
PrasugrelFenoprofen
Severe
How does the drug interact with Aplet 5mg Tablet:
Co-administration of Fenoprofen with Aplet 5mg Tablet can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Aplet 5mg Tablet with Fenoprofen can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Aplet 5mg Tablet to prevent unpleasant side-effects. Alcohol intake might increase the risk of stomach or intestine bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Safe if prescribed

Aplet 5mg Tablet does not affect your ability to drive. However, do not drive or operate heavy machinery if you are not alert.

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Liver

Caution

Dose adjustment may be needed. Aplet 5mg Tablet should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver impairment/liver disease or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Aplet 5mg Tablet should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment/kidney disease or any concerns regarding this.

bannner image

Children

Unsafe

Aplet 5mg Tablet should not be used by children, as the efficacy and safety have not been established.

Have a query?

FAQs

Aplet 5mg Tablet is used to prevent the formation of blood clots, thereby reducing the chance of having a heart attack or stroke in future.

Aplet 5mg Tablet works by inhibiting the clumping of platelets, thereby reduces the chance of blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke.

Aplet 5mg Tablet prevents the formation of blood clots so it might increase the risk of bleeding during injury, cut or surgery. Therefore, be cautious while using sharp objects. Consult a doctor immediately if you notice excess bleeding. Let your doctor know if you are going to have any scheduled surgery as your doctor might reduce the dose to avoid excess bleeding during surgery.

Please do not stop taking Aplet 5mg Tablet on your own, as it might increase the risk of a heart attack. Continue taking Aplet 5mg Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Aplet 5mg Tablet .

Aplet 5mg Tablet may cause anaemia (low haemoglobin and low red blood cell count). So it would be best if you include iron-rich food in your diet to prevent anaemia.

Avoid taking non-steroidal anti-inflammatory drugs (pain-relieving medicines) like aspirin along with Aplet 5mg Tablet as it may increase the risk of gastrointestinal ulcer and bleeding.

It can take 30 minutes to 4 hours for maximal effect.

Common side effects of Aplet 5mg Tablet may include nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, purpura (blood leakage under the skin), indigestion, and bruising. If you experience these side effects persistently, you are advised to talk to your doctor.

Caution should be exercised when using the Aplet 5mg Tablet . Aplet 5mg Tablet may cause a blood clotting problem called thrombotic thrombocytopenic purpura (TTP). TTP is a rare but serious medical condition that can be deadly. Sometimes, it may cause severe or life-threatening bleeding. So, it should be taken under the supervision of the doctor. If you face any uncommon adverse events, consult the doctor immediately.

Take Aplet 5mg Tablet at around the same time every day. Follow the directions as directed by the physician.

No specific symptoms have been reported. If you experience any issues, kindly report them and seek medical attention.

Do not take more than the prescribed dose of Aplet 5mg Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

No, Aplet 5mg Tablet is a prescription medication, and it should be used only if prescribed by the doctor.

Aplet 5mg Tablet contains Prasugrel, an anti-platelet medication.

Aplet 5mg Tablet may cause side effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, purpura (blood leakage under the skin), indigestion and bruising. You are advised to talk to your doctor if you experience these side effects persistently.

Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - APL0013

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:49 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022307s002lbl.pdf
  2. https://www.hey.nhs.uk/wp/wp-content/uploads/2016/03/prasugrel.pdf
  3. https://www.drugs.com/drug-interactions/prasugrel.html
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