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Drug-Drug Interactions
Drug-Drug Interactions
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Using Aplotel-AM Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Aplotel-AM Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Co-administration of Aliskiren with Aplotel-AM Tablet can increase the risk of hyperkalemia (high potassium levels in the blood).
How to manage the interaction:
Taking Aplotel-AM Tablet with Aliskiren can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Tizanidine and Aplotel-AM Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Aplotel-AM Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Coadministration of Aplotel-AM Tablet and Idelalisib may raise Aplotel-AM Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).
How to manage the interaction:
Although taking Aplotel-AM Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
Using phenobarbital and Aplotel-AM Tablet may drastically lower Aplotel-AM Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of phenobarbital with Aplotel-AM Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Aplotel-AM Tablet and mitotane together may drastically lower Aplotel-AM Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Aplotel-AM Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Coadministration of Aplotel-AM Tablet with itraconazole may significantly raise the blood levels and effects of Aplotel-AM Tablet.
How to manage the interaction:
Aplotel-AM Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
Coadministration of lemborexant and Aplotel-AM Tablet may increase the blood levels of lemborexant.
How to manage the interaction:
Although co-administration of Aplotel-AM Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
Coadministration of Aplotel-AM Tablet and Rifapentine may significantly reduce the blood levels of Aplotel-AM Tablet, which may make the medication less effective.
How to manage the interaction:
There may be a possibility of interaction between Aplotel-AM Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Coadministration of Aplotel-AM Tablet and carbamazepine together may significantly reduce Aplotel-AM Tablet blood levels, making the medicine less effective.
How to manage the interaction:
Although there is an interaction between Aplotel-AM Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Taking Aplotel-AM Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Aplotel-AM Tablet.
Product Substitutes
Alcohol
Unsafe
It is unsafe to consume alcohol since alcohol consumption may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.
Pregnancy
Unsafe
Aplotel-AM Tablet is not recommended during pregnancy as it may harm the foetus. Consult your doctor if you are pregnant, think you may be pregnant or are planning to become pregnant. This medicine should be discontinued as soon as pregnancy is detected.
Breast Feeding
Caution
Please consult your doctor before taking Aplotel-AM Tablet if you are breastfeeding. Your doctor will decide if you need to take Aplotel-AM Tablet or breastfeed. You should not do both.
Driving
Caution
Aplotel-AM Tablet may cause side effects like dizziness, headaches, and nausea, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive until you are mentally alert.
Liver
Caution
Inform your doctor if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver condition.
Kidney
Caution
Inform your doctor Aplotel-AM Tablet if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney condition.
Children
Unsafe
Aplotel-AM Tablet is not recommended to use in children. Please consult the doctor if you have any concerns regarding this.
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