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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Arifine 20 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines. It contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. It improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, it improves mood swings, depression, and other psychotic problems. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production.
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Whats That

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Composition :

ARIPIPRAZOLE-20MG

Manufacturer/Marketer :

Icon Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Arifine 20 Tablet

Arifine 20 Tablet is an antipsychotic medicine used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Arifine 20 Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused by disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Arifine 20 Tablet contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Arifine 20 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arifine 20 Tablet improves mood swings, depression, and other psychotic problems. 

Take Arifine 20 Tablet as prescribed. Your doctor will advise you how often you take Arifine 20 Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine 20 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Arifine 20 Tablet or any other medicines, please tell your doctor. Arifine 20 Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine 20 Tablet if you are pregnant or breastfeeding, and consult a doctor. Arifine 20 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behaviour while taking Arifine 20 Tablet , please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 20 Tablet .

Uses of Arifine 20 Tablet

Treatment of Schizophrenia, Mania, Bipolar disorder, and irritability associated with an autism spectrum disorder

Directions for Use

Tablet: Take it with or without food as advised by the doctor, and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Arifine 20 Tablet contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Arifine 20 Tablet inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Arifine 20 Tablet improves overall behaviour and thoughts and helps people have a better social life and comfortably do daily activities. Arifine 20 Tablet may be used in combination with other medicines to treat depression. Additionally, Arifine 20 Tablet is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

How Arifine 20 Tablet Works

Arifine 20 Tablet contains Aripiprazole, which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Arifine 20 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arifine 20 Tablet improves mood swings, depression, and other psychotic problems.

Storage

Store in a cool and dry place away from sunlight
Side effects of Arifine 20 Tablet
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

What if I have taken an overdose of Arifine 20 Tablet

Do not take more than the prescribed dose of Arifine 20 Tablet as it may cause overdose. The symptoms of overdose include confusion, tremors, drowsiness, vomiting, aggression, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Arifine 20 Tablet or any other medicines, please tell your doctor. Arifine 20 Tablet should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine 20 Tablet if you are pregnant or breastfeeding and consult a doctor. Arifine 20 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arifine 20 Tablet , please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Arifine 20 Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 20 Tablet .

Drug-Drug Interactions

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AripiprazoleMetoclopramide
Critical
AripiprazolePrimidone
Severe

Drug-Drug Interactions

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AripiprazoleMetoclopramide
Critical
How does the drug interact with Arifine 20 Tablet:
Co-administration of Metoclopramide with Arifine 20 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Arifine 20 Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AripiprazolePrimidone
Severe
How does the drug interact with Arifine 20 Tablet:
Coadministration of Arifine 20 Tablet and primidone may decrease the blood levels of Arifine 20 Tablet, which may make Arifine 20 Tablet less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between primidone and Arifine 20 Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AripiprazoleRifabutin
Severe
How does the drug interact with Arifine 20 Tablet:
Taking rifabutin with Arifine 20 Tablet can reduce the blood levels of Arifine 20 Tablet.

How to manage the interaction:
Although taking Arifine 20 Tablet and Rifabutin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
AripiprazoleIohexol
Severe
How does the drug interact with Arifine 20 Tablet:
Arifine 20 Tablet and Iohexol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Arifine 20 Tablet and Iohexol together can cause an interaction, it can be taken if a doctor has suggested it. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.
AripiprazoleRifapentine
Severe
How does the drug interact with Arifine 20 Tablet:
Coadministration of Rifapentine may significantly reduce the blood levels of Arifine 20 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Arifine 20 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any unusual symptoms, it's important to let a doctor know. Do not stop using any medications without talking to a doctor.
AripiprazoleTopiramate
Severe
How does the drug interact with Arifine 20 Tablet:
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Arifine 20 Tablet.

How to manage the interaction:
Co-administration of Arifine 20 Tablet with Topiramate can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult the doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced sweating or a fever. Do not discontinue any medications without consulting a doctor.
AripiprazoleKetamine
Severe
How does the drug interact with Arifine 20 Tablet:
Using ketamine together with Arifine 20 Tablet may increase risk of side effects.

How to manage the interaction:
Co-administration of Ketamine with Arifine 20 Tablet can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how you're breathing. If you notice any of these signs - feeling dizzy, tired, confused, having trouble focusing, feeling too sleepy, or having trouble breathing - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AripiprazoleMirabegron
Severe
How does the drug interact with Arifine 20 Tablet:
Combining Arifine 20 Tablet with Mirabegron can increase the levels of Arifine 20 Tablet in the body. This can lead to increased risk or severity of side effects.

How to manage the interaction:
Although taking Mirabegron and Arifine 20 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazolePhenytoin
Severe
How does the drug interact with Arifine 20 Tablet:
Phenytoin may decrease the blood levels of Arifine 20 Tablet, which may make Arifine 20 Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Phenytoin and Arifine 20 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
AripiprazoleEnzalutamide
Severe
How does the drug interact with Arifine 20 Tablet:
When Arifine 20 Tablet is taken with Enzalutamide, the amount of Arifine 20 Tablet in the blood may decrease. This might reduce Arifine 20 Tablet's ability to effectively treat disease.

How to manage the interaction:
Although there is a possible interaction between Enzalutamide and Arifine 20 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Arifine 20 Tablet .

  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.

  • Cut down sugars, salt and saturated fats.

  • Drink adequate water to keep the body hydrated.

  • Do regular exercise and maintain a stable weight as Arifine 20 Tablet may cause weight gain.

  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Arifine 20 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating.

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Pregnancy

Unsafe

Arifine 20 Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy, especially in the third trimester as it may cause adverse effects in the newborn baby. Arifine 20 Tablet may cause extrapyramidal and/or withdrawal symptoms in newborn babies with third-trimester exposure.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Arifine 20 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Arifine 20 Tablet may cause dizziness or vision problems such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Arifine 20 Tablet .

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Liver

Caution

Take Arifine 20 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Arifine 20 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Arifine 20 Tablet is not recommended for children below 15 years due to the increased risk of adverse effects. However, please consult a doctor before giving Arifine 20 Tablet to children.

Have a query?

FAQs

Arifine 20 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.

Arifine 20 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and prevents its overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbelief and unfriendliness) of schizophrenia. Also, Arifine 20 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Thereby, Arifine 20 Tablet improves behaviour, thoughts and helps in having a better social life and enables to comfortably do daily activities.

No, you are not recommended to take Arifine 20 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Arifine 20 Tablet in the blood leading to increased adverse effects. However, please consult a doctor before taking Arifine 20 Tablet with other medicines.

Arifine 20 Tablet may cause weight gain in some patients but it is not necessary for everyone taking Arifine 20 Tablet to experience this side effect. However, in order to avoid gaining weight while taking Arifine 20 Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

Arifine 20 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Arifine 20 Tablet .

Yes, Arifine 20 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Arifine 20 Tablet and inform your doctor if you have diabetes before taking Arifine 20 Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.

No, you are not recommended to stop taking Arifine 20 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Arifine 20 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Arifine 20 Tablet , please consult your doctor so that the dose may be gradually reduced.

Yes, Arifine 20 Tablet is a mood stabilizer. It helps calm the mood and treats mood-related problems.

Arifine 20 Tablet might start working within a few days or weeks. However, you may notice the full benefits of Arifine 20 Tablet after 2-3 months. Continue taking Arifine 20 Tablet for the prescribed duration to prevent the recurrence of symptoms.

Arifine 20 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.

Elderly patients more than 65 years old with dementia-related psychosis treated with Arifine 20 Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Arifine 20 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.

Avoid intake of grapefruit juice with Arifine 20 Tablet as it may reduce the effect of Arifine 20 Tablet . Also, avoid alcohol consumption with Arifine 20 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Arifine 20 Tablet .

Consult the doctor if you are diabetic as Arifine 20 Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.

Arifine 20 Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine 20 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Plot No. 128-B, Phase 1 & 2 G.I.D.C., Naroda, Ahmedabad - 382330. (Gujarat)
Other Info - ARI0262

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