ARIPHRENZ 20MG TABLET
MRP ₹12.4
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Composition :
ARIPIPRAZOLE-20MG
Manufacturer/Marketer :
Alkem Laboratories Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
About ARIPHRENZ 20MG TABLET
ARIPHRENZ 20MG TABLET is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is characterised by uncontrollable, repetitive movements or unwanted sounds (tics).
ARIPHRENZ 20MG TABLET contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia.
Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects do not require medical attention. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to ARIPHRENZ 20MG TABLET or any other medicines, please tell your doctor. Avoid taking ARIPHRENZ 20MG TABLET if you are pregnant or breastfeeding, and consult a doctor. ARIPHRENZ 20MG TABLET is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking ARIPHRENZ 20MG TABLET, please get in touch with a doctor immediately.
Uses of ARIPHRENZ 20MG TABLET
ARIPHRENZ 20MG TABLET is primarily used in the treatment of schizophrenia. Its specific uses are as follows:
- Schizophrenia: ARIPHRENZ 20MG TABLET is used to treat schizophrenia in adults and children aged 13 years and older. It helps manage negative symptoms of schizophrenia, such as lack of emotion, social isolation, poor attention, and memory loss.
- Bipolar I Disorder (Manic Depression): ARIPHRENZ 20MG TABLET is used alone or in combination with mood stabilisers (like valproate or lithium) to treat acute episodes of mania (abnormally elevated mood) in adults and children aged 10 years and older. It helps stabilise mood and reduce irritability and hyperactivity.
- Major Depressive Disorder (MDD) - As Adjunctive Therapy: ARIPHRENZ 20MG TABLET is used in combination with antidepressants to treat MDD when antidepressants alone are not effective. It helps improve mood, energy levels, and overall functioning.
- Tourette Syndrome (TS): ARIPHRENZ 20MG TABLET is used to reduce the severity and frequency of tics (sudden, uncontrollable vocal sounds or movements) in children over 6 years with TS.
- Autism Spectrum Disorder (ASD): ARIPHRENZ 20MG TABLET is used to manage the symptoms of ASD in children over 6 years, such as mood swings, irritability, aggression, tantrums, and self-injurious behaviour.
- Maintenance Treatment: ARIPHRENZ 20MG TABLET is used for long-term management of schizophrenia and bipolar disorder to prevent relapse or worsening of symptoms.
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Directions for Use
- ARIPHRENZ 20MG TABLET can be taken with or without food, as advised by the doctor.
- It is usually taken once daily or as prescribed by your doctor.
- Swallow ARIPHRENZ 20MG TABLET as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- ARIPHRENZ 20MG TABLET contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression.
- ARIPHRENZ 20MG TABLET inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbeliefs, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia.
- ARIPHRENZ 20MG TABLET improves overall behaviour and thoughts, helping people lead a better social life and comfortably perform daily activities.
- ARIPHRENZ 20MG TABLET may be used in combination with other medicines to treat depression.
- Additionally, ARIPHRENZ 20MG TABLET is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).
How ARIPHRENZ 20MG TABLET Works
ARIPHRENZ 20MG TABLET contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the positive symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia. ARIPHRENZ 20MG TABLET improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, ARIPHRENZ 20MG TABLET improves mood swings, depression, and other psychotic problems.
Storage
• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ariphrenz 20mg Tablet
- Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
- Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
- Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
Overcome Medication-Induced Nausea: A 9-Step Plan
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
- Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
- Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
- Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
- Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
- Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
- Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
- Restlessness is related to mental health and needs medical attention if it's severe.
- Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
- Prevent smoking as it can impact your calmness of body and mind.
- Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
- Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
- Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
- Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
- Maintain healthy weight and advance general health depend on eating a balanced diet.
- Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
- Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
- Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
- Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
- Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
- Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
- Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
What if I have taken an overdose of ARIPHRENZ 20MG TABLET
Do not take more than the prescribed dose of ARIPHRENZ 20MG TABLET, as it may cause an overdose. Symptoms of an overdose may include confusion, tremors, drowsiness, vomiting, aggression, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.
Drug Warnings
- If you are allergic to ARIPHRENZ 20MG TABLET or any other medicines, please tell your doctor.
- ARIPHRENZ 20MG TABLET should be used with caution in elderly patients over 65, as there is an increased risk of adverse reactions, including dizziness, changes in mobility and balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness.
- Avoid taking ARIPHRENZ 20MG TABLET if you are pregnant or breastfeeding, and consult a doctor.
- ARIPHRENZ 20MG TABLET is not recommended for children below 13 years of age.
- If you have any self-harming thoughts or behaviour while taking ARIPHRENZ 20MG TABLET, please get in touch with a doctor immediately.
- If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or you are advised to stop taking ARIPHRENZ 20MG TABLET.
- If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, or kidney or liver problems, inform your doctor before taking ARIPHRENZ 20MG TABLET.
Drug-Drug Interactions
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Ariphrenz 20mg Tablet:
Co-administration of Metoclopramide with Ariphrenz 20mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Ariphrenz 20mg Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Co-administration of Metoclopramide with Ariphrenz 20mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Ariphrenz 20mg Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ariphrenz 20mg Tablet:
Taking carbamazepine and Ariphrenz 20mg Tablet together can reduce the effects of Ariphrenz 20mg Tablet which may make the medication less effective.
How to manage the interaction:
Taking carbamazepine and Ariphrenz 20mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking carbamazepine and Ariphrenz 20mg Tablet together can reduce the effects of Ariphrenz 20mg Tablet which may make the medication less effective.
How to manage the interaction:
Taking carbamazepine and Ariphrenz 20mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AripiprazoleHydrocodone
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
Using Ariphrenz 20mg Tablet together with Hydrocodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Although taking Ariphrenz 20mg Tablet and Hydrocodone together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like trouble breathing, feeling very sleepy, or having trouble focusing, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
Using Ariphrenz 20mg Tablet together with Hydrocodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Although taking Ariphrenz 20mg Tablet and Hydrocodone together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like trouble breathing, feeling very sleepy, or having trouble focusing, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
Using ketamine together with Ariphrenz 20mg Tablet may increase risk of side effects.
How to manage the interaction:
Co-administration of Ketamine with Ariphrenz 20mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how you're breathing. If you notice any of these signs - feeling dizzy, tired, confused, having trouble focusing, feeling too sleepy, or having trouble breathing - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Using ketamine together with Ariphrenz 20mg Tablet may increase risk of side effects.
How to manage the interaction:
Co-administration of Ketamine with Ariphrenz 20mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how you're breathing. If you notice any of these signs - feeling dizzy, tired, confused, having trouble focusing, feeling too sleepy, or having trouble breathing - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AripiprazoleFosphenytoin
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
When Ariphrenz 20mg Tablet and Fosphenytoin are taken together, can reduce the levels of Ariphrenz 20mg Tablet levels in the body. This can lead to low treatment outcomes.
How to manage the interaction:
Although taking Ariphrenz 20mg Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
When Ariphrenz 20mg Tablet and Fosphenytoin are taken together, can reduce the levels of Ariphrenz 20mg Tablet levels in the body. This can lead to low treatment outcomes.
How to manage the interaction:
Although taking Ariphrenz 20mg Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Ariphrenz 20mg Tablet.
How to manage the interaction:
Co-administration of Ariphrenz 20mg Tablet with Topiramate can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult the doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced sweating or a fever. Do not discontinue any medications without consulting a doctor.
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Ariphrenz 20mg Tablet.
How to manage the interaction:
Co-administration of Ariphrenz 20mg Tablet with Topiramate can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult the doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced sweating or a fever. Do not discontinue any medications without consulting a doctor.
AripiprazoleEnzalutamide
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
When Ariphrenz 20mg Tablet is taken with Enzalutamide, the amount of Ariphrenz 20mg Tablet in the blood may decrease. This might reduce Ariphrenz 20mg Tablet's ability to effectively treat disease.
How to manage the interaction:
Although there is a possible interaction between Enzalutamide and Ariphrenz 20mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
When Ariphrenz 20mg Tablet is taken with Enzalutamide, the amount of Ariphrenz 20mg Tablet in the blood may decrease. This might reduce Ariphrenz 20mg Tablet's ability to effectively treat disease.
How to manage the interaction:
Although there is a possible interaction between Enzalutamide and Ariphrenz 20mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
AripiprazoleDezocine
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
Using Ariphrenz 20mg Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Ariphrenz 20mg Tablet with Dezocine together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Using Ariphrenz 20mg Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Ariphrenz 20mg Tablet with Dezocine together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
Coadministration of Ariphrenz 20mg Tablet and primidone may decrease the blood levels of Ariphrenz 20mg Tablet, which may make Ariphrenz 20mg Tablet less effective in treating the condition.
How to manage the interaction:
Although there is an interaction between primidone and Ariphrenz 20mg Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Ariphrenz 20mg Tablet and primidone may decrease the blood levels of Ariphrenz 20mg Tablet, which may make Ariphrenz 20mg Tablet less effective in treating the condition.
How to manage the interaction:
Although there is an interaction between primidone and Ariphrenz 20mg Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Ariphrenz 20mg Tablet:
Using Ariphrenz 20mg Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Ariphrenz 20mg Tablet with Butorphanol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend other options that won't cause any problems. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
Using Ariphrenz 20mg Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Ariphrenz 20mg Tablet with Butorphanol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend other options that won't cause any problems. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Limit the intake of caffeine as it may reduce the effectiveness of ARIPHRENZ 20MG TABLET.
- Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards, and herring.
- Cut down on sugars, salt, and saturated fats.
- Drink adequate water to keep the body hydrated.
- Engage in regular exercise and maintain a stable weight, as ARIPHRENZ 20MG TABLET may contribute to weight gain.
- Avoid alcohol consumption, as it may increase drowsiness.
Habit Forming
No
Therapeutic Class
ANTIPSYCHOTICS
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Alcohol
Unsafe
Avoid alcohol consumption while taking ARIPHRENZ 20MG TABLET, as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.
Pregnancy
Unsafe
ARIPHRENZ 20MG TABLET is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.
Breast Feeding
Unsafe
Avoid breastfeeding while taking ARIPHRENZ 20MG TABLET, as it may be excreted in breast milk and cause adverse effects in the baby.
Driving
Unsafe
ARIPHRENZ 20MG TABLET may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking ARIPHRENZ 20MG TABLET.
Liver
Caution
Take ARIPHRENZ 20MG TABLET with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.
Kidney
Caution
Take ARIPHRENZ 20MG TABLET with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.
Children
Unsafe
ARIPHRENZ 20MG TABLET is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving ARIPHRENZ 20MG TABLET to children.
Heart
Caution
Exercise caution while taking ARIPHRENZ 20MG TABLET if you have any cardiac problems due to the risk of hypotension and irregular heartbeat.
Geriatrics
Consult your doctor
Limited information available for use of ARIPHRENZ 20MG TABLET in elderly patients. Please consult your doctor.
FAQs
Country of origin
India
Manufacturer/Marketer address
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ARI0151
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Author Details
Reference
- https://www.drugs.com/aripiprazole.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021436s038,021713s030,021729s022,021866s023lbl.pdf
- https://www.medicines.org.uk/emc/files/pil.7073.pdf
- https://www.ema.europa.eu/en/documents/product-information/aripiprazole-sandoz-epar-product-information_en.pdf
- https://www.nps.org.au/assets/medicines/bd27ea92-f63b-40ae-acc6-a74a00599b6a.pdf
- https://www.medsafe.govt.nz/consumers/cmi/a/aripiprazolesandoz.pdf
