Axepine MD 20 Tablet 10's
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About Axepine MD 20 Tablet
Axepine MD 20 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is characterised by uncontrollable, repetitive movements or unwanted sounds (tics).
Axepine MD 20 Tablet contains Aripiprazole, which stabilises and blocks the dopamine and serotonin receptors in the brain, preventing their overactivity, thereby controlling the symptoms like hallucinations, misbeliefs, and unfriendly characteristics of schizophrenia.
Some people may experience drowsiness, headache, tiredness, akathisia (an inability to sit still), difficulty sleeping, lightheadedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects do not require medical attention. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Axepine MD 20 Tablet or any other medicines, please tell your doctor. Avoid taking Axepine MD 20 Tablet if you are pregnant or breastfeeding, and consult a doctor. Axepine MD 20 Tablet is not recommended for children below 13 years of age. If you have any self-harming thoughts or behaviour while taking Axepine MD 20 Tablet , please get in touch with a doctor immediately.
Uses of Axepine MD 20 Tablet
Axepine MD 20 Tablet is primarily used in the treatment of schizophrenia. Its specific uses are as follows:
- Schizophrenia: Axepine MD 20 Tablet is used to treat schizophrenia in adults and children aged 13 years and older. It helps manage negative symptoms of schizophrenia, such as lack of emotion, social isolation, poor attention, and memory loss.
- Bipolar I Disorder (Manic Depression): Axepine MD 20 Tablet is used alone or in combination with mood stabilisers (like valproate or lithium) to treat acute episodes of mania (abnormally elevated mood) in adults and children aged 10 years and older. It helps stabilise mood and reduce irritability and hyperactivity.
- Major Depressive Disorder (MDD) - As Adjunctive Therapy: Axepine MD 20 Tablet is used in combination with antidepressants to treat MDD when antidepressants alone are not effective. It helps improve mood, energy levels, and overall functioning.
- Tourette Syndrome (TS): Axepine MD 20 Tablet is used to reduce the severity and frequency of tics (sudden, uncontrollable vocal sounds or movements) in children over 6 years with TS.
- Autism Spectrum Disorder (ASD): Axepine MD 20 Tablet is used to manage the symptoms of ASD in children over 6 years, such as mood swings, irritability, aggression, tantrums, and self-injurious behaviour.
- Maintenance Treatment: Axepine MD 20 Tablet is used for long-term management of schizophrenia and bipolar disorder to prevent relapse or worsening of symptoms.
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Directions for Use
- Axepine MD 20 Tablet can be taken with or without food, as advised by the doctor.
- It is usually taken once daily or as prescribed by your doctor.
- Swallow Axepine MD 20 Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Key Benefits
- Axepine MD 20 Tablet contains Aripiprazole, which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression.
- Axepine MD 20 Tablet inhibits the dopamine receptor in our brain, thereby controlling the positive symptoms (like hallucinations, misbeliefs, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia.
- Axepine MD 20 Tablet improves overall behaviour and thoughts, helping people lead a better social life and comfortably perform daily activities.
- Axepine MD 20 Tablet may be used in combination with other medicines to treat depression.
- Additionally, Axepine MD 20 Tablet is also used to reduce the severity of unwanted sounds (tics) in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).
How Axepine MD 20 Tablet Works
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- Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
- Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
- Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
- Try relaxing techniques like deep breathing, mindfulness meditation and any others.
- Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
- Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
- Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
- Talk to your doctor about your back pain and potential medication substitutes or dose changes.
- Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
- To lessen the tension on your back, sit and stand upright and maintain proper posture.
- To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
- Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
- Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
- To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
- Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
- Back discomfort can worsen by bending, twisting, and heavy lifting.
- Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
- Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
- Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
- Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
- Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
- Restlessness is related to mental health and needs medical attention if it's severe.
- Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
- Prevent smoking as it can impact your calmness of body and mind.
- Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
- Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
- Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
- Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
- Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
- Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
- Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
- Restlessness is related to mental health and needs medical attention if it's severe.
- Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
- Prevent smoking as it can impact your calmness of body and mind.
- Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
- Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
What if I have taken an overdose of Axepine MD 20 Tablet
Drug Warnings
- If you are allergic to Axepine MD 20 Tablet or any other medicines, please tell your doctor.
- Axepine MD 20 Tablet should be used with caution in elderly patients over 65, as there is an increased risk of adverse reactions, including dizziness, changes in mobility and balance, orthostatic hypotension (a drop in blood pressure when standing up), and drowsiness.
- Avoid taking Axepine MD 20 Tablet if you are pregnant or breastfeeding, and consult a doctor.
- Axepine MD 20 Tablet is not recommended for children below 13 years of age.
- If you have any self-harming thoughts or behaviour while taking Axepine MD 20 Tablet , please get in touch with a doctor immediately.
- If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or you are advised to stop taking Axepine MD 20 Tablet .
- If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements, especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, or kidney or liver problems, inform your doctor before taking Axepine MD 20 Tablet .
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Metoclopramide with Axepine MD 20 Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Axepine MD 20 Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Axepine MD 20 Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Axepine MD 20 Tablet with Oxycodone together can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
Using Axepine MD 20 Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Axepine MD 20 Tablet with Butorphanol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend other options that won't cause any problems. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
Combining Axepine MD 20 Tablet with Mirabegron can increase the levels of Axepine MD 20 Tablet in the body. This can lead to increased risk or severity of side effects.
How to manage the interaction:
Although taking Mirabegron and Axepine MD 20 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
Coadministration of Rifapentine may significantly reduce the blood levels of Axepine MD 20 Tablet, which may make the medication less effective in treating the condition.
How to manage the interaction:
There may be a possibility of interaction between Axepine MD 20 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any unusual symptoms, it's important to let a doctor know. Do not stop using any medications without talking to a doctor.
Using Morphine together with Axepine MD 20 Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Morphine with Axepine MD 20 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without consulting a doctor.
Taking bupropion with Axepine MD 20 Tablet may raise the chance of seizures (fits), which can happen with either medicine. Furthermore, bupropion can raise Axepine MD 20 Tablet levels in the blood, which may increase other side effects.
How to manage the interaction:
Co-administration of bupropion along with Axepine MD 20 Tablet can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
Using Axepine MD 20 Tablet together with Methadone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Taking Axepine MD 20 Tablet with Methadone together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
Using Axepine MD 20 Tablet together with Hydromorphone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Although taking Axepine MD 20 Tablet and Hydromorphone together can cause an interaction, it can be taken if a doctor has suggested it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Do not stop using any medications without a doctor's advice.
Taking rifabutin with Axepine MD 20 Tablet can reduce the blood levels of Axepine MD 20 Tablet.
How to manage the interaction:
Although taking Axepine MD 20 Tablet and Rifabutin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Limit the intake of caffeine as it may reduce the effectiveness of Axepine MD 20 Tablet .
- Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards, and herring.
- Cut down on sugars, salt, and saturated fats.
- Drink adequate water to keep the body hydrated.
- Engage in regular exercise and maintain a stable weight, as Axepine MD 20 Tablet may contribute to weight gain.
- Avoid alcohol consumption, as it may increase drowsiness.
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Alcohol
Safe if prescribed
Avoid alcohol consumption while taking Axepine MD 20 Tablet , as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty concentrating.
Pregnancy
Consult your doctor
Axepine MD 20 Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester, as it may cause extrapyramidal and/or withdrawal symptoms in newborn babies.
Breast Feeding
Consult your doctor
Avoid breastfeeding while taking Axepine MD 20 Tablet , as it may be excreted in breast milk and cause adverse effects in the baby.
Driving
Safe if prescribed
Axepine MD 20 Tablet may cause dizziness or vision problems, such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Axepine MD 20 Tablet .
Liver
Consult your doctor
Take Axepine MD 20 Tablet with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.
Kidney
Consult your doctor
Take Axepine MD 20 Tablet with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.
Children
Safe if prescribed
Axepine MD 20 Tablet is not recommended for children below 13 years due to the increased risk of adverse effects. However, please consult a doctor before giving Axepine MD 20 Tablet to children.
Heart
Exercise caution while taking Axepine MD 20 Tablet if you have any cardiac problems due to the risk of hypotension and irregular heartbeat.
Geriatrics
Consult your doctor
Limited information available for use of Axepine MD 20 Tablet in elderly patients. Please consult your doctor.
FAQs
Axepine MD 20 Tablet is used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, it also helps in managing mental depression along with other antidepressant medicines.
Axepine MD 20 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and preventing their overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbeliefs and unfriendliness) of schizophrenia. Also, Axepine MD 20 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Therefore, Axepine MD 20 Tablet improves behaviour and thoughts, enhances social life, and helps one comfortably perform daily activities.
No, you are not recommended to take Axepine MD 20 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Axepine MD 20 Tablet in the blood, leading to increased adverse effects. However, please consult a doctor before taking Axepine MD 20 Tablet with other medicines.
Axepine MD 20 Tablet may cause weight gain in some patients, but it is not a necessary side effect for everyone taking Axepine MD 20 Tablet . However, to avoid gaining weight while taking Axepine MD 20 Tablet , it is advisable to engage in regular exercise and limit high-calorie drinks. Instead, opt for non-alcoholic beverages, herbal tea, and lemon water.
Axepine MD 20 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people, as it may cause severe adverse effects, including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Axepine MD 20 Tablet .
Yes, Axepine MD 20 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Axepine MD 20 Tablet , and you should inform your doctor if you have diabetes before starting Axepine MD 20 Tablet . However, if you experience dry mouth, increased thirst or urination, or a fruity breath odour, please consult a doctor, as these may be signs of high blood sugar.
No, you are not recommended to stop taking Axepine MD 20 Tablet without consulting your doctor, as it may worsen the condition or cause recurring symptoms. Therefore, take Axepine MD 20 Tablet for as long as your doctor has prescribed it. If you experience any difficulty while taking Axepine MD 20 Tablet , please consult your doctor so that the dose can be gradually reduced.
Yes, Axepine MD 20 Tablet is a mood stabiliser. It helps calm the mood and treats mood-related problems.
Axepine MD 20 Tablet might start working within a few days or weeks. However, you may notice the full benefits of Axepine MD 20 Tablet after 2-3 months. Continue taking Axepine MD 20 Tablet for the prescribed duration to prevent the recurrence of symptoms.
Axepine MD 20 Tablet may cause priapism (prolonged and painful erection) in some people. Please consult the doctor if you have any concerns.
Elderly patients more than 65 years old with dementia-related psychosis treated with Axepine MD 20 Tablet can be at an increased risk of death. Increased risk of suicidal thinking and behaviour changes has been observed in children, adolescents, and young adults taking Axepine MD 20 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.
Avoid intake of grapefruit juice with Axepine MD 20 Tablet as it may reduce the effect of Axepine MD 20 Tablet . Also, avoid alcohol consumption with Axepine MD 20 Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty concentrating. Do not drive if you feel dizzy or have vision disturbances after taking Axepine MD 20 Tablet .
Consult the doctor if you are diabetic, as Axepine MD 20 Tablet may cause high blood sugar levels. Regular monitoring of blood glucose levels is advised.
Axepine MD 20 Tablet may cause side effects like drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Axepine MD 20 Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.
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Reference
- https://www.drugs.com/aripiprazole.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021436s038,021713s030,021729s022,021866s023lbl.pdf
- https://www.medicines.org.uk/emc/files/pil.7073.pdf
- https://www.ema.europa.eu/en/documents/product-information/aripiprazole-sandoz-epar-product-information_en.pdf
- https://www.nps.org.au/assets/medicines/bd27ea92-f63b-40ae-acc6-a74a00599b6a.pdf
- https://www.medsafe.govt.nz/consumers/cmi/a/aripiprazolesandoz.pdf
