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compositionComposition:AMOXAPINE-50MG
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Prescription Medicine
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Auxadep-50 Tablet is used to treat depression, anxiety, and agitation. It contains Amoxapine, a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for mental health and mood changes. This medicine helps improve mood and feelings.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMOXAPINE-50MG

Manufacturer/Marketer :

Jagsam Pharma

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Auxadep-50 Tablet

Auxadep-50 Tablet is a prescription medication primarily used to treat depression. It is especially helpful for patients experiencing depressive symptoms accompanied by anxiety, tension, or agitation. This medication belongs to a class of drugs that help restore balance to certain chemical messengers in the brain.

To get the best results, you must take Auxadep-50 Tablet consistently every day exactly as your doctor prescribes. You can take this medicine with or without food, though taking it with meals can help prevent stomach upset. Incorporating a regular sleep schedule, eating a balanced diet, and engaging in light daily physical activity can also support your treatment outcomes.

While taking this medicine, some people may experience common side effects like drowsiness, dry mouth, or constipation. If you face specific serious side effects, such as unusual muscle stiffness, tremors, a rapid heartbeat, or sudden changes in your mental state, you should consult your doctor right away.

Before you begin taking Auxadep-50 Tablet , tell your doctor if you have a history of heart disease, seizures, glaucoma, or difficulty urinating. Do not take this if you are currently recovering from a recent heart attack. It is also important that you do not take this if you have used certain other antidepressant medicines within the last two weeks.

This medicine can interact with other drugs that make you sleepy, and drinking alcohol while taking it can dangerously increase drowsiness. Additionally, smoking may change how quickly your body processes this medication. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, you should consult your doctor or pharmacist to discuss the risks and benefits before starting treatment.

Uses of Auxadep-50 Tablet

Auxadep-50 Tablet is used to treat depression. The detailed uses of Auxadep-50 Tablet are as follows:

  • Depression: Auxadep-50 Tablet helps relieve persistent sadness, loss of interest in activities, and fatigue by balancing critical chemicals in the brain.
  • Depression with anxiety or agitation: It helps calm nervous tension and restlessness that frequently occur alongside depressive disorders.
  • Severe or psychotic depression: It helps manage severe depressive states, including those where individuals experience distorted thoughts or see and hear things that are not there.

Key Benefits

Auxadep-50 Tablet helps manage depression and anxiety by restoring the balance of important brain chemicals. With regular use as prescribed, it helps improve mood, reduce anxiety symptoms, and support better emotional well-being.

  • Improves Mood: By balancing key neurotransmitters in the brain, this medicine helps reduce symptoms of depression, improve emotional well-being, and make it easier to return to daily activities.
  • Reduces Anxiety Symptoms: This medicine helps relieve anxiety-related symptoms such as excessive worry, restlessness, and physical tension, promoting a greater sense of calm.
  • Promotes Better Sleep and Daily Functioning: By improving mood and reducing anxiety, this medicine supports healthier sleep patterns, improves concentration, and helps you feel more rested and better able to manage everyday responsibilities.

Directions for Use

  • Auxadep-50 Tablet can be taken with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Auxadep-50 Tablet as a whole with a glass of water.
  • Do not break, chew or crush Auxadep-50 Tablet .

How Auxadep-50 Tablet Works

Auxadep-50 Tablet contains amoxapine, which works by increasing the levels of certain natural chemicals in your brain, specifically norepinephrine and serotonin. These chemicals act as messengers between your brain cells and are essential for regulating your mood, emotions, and overall sense of well-being. In addition to boosting these mood-regulating chemicals, Auxadep-50 Tablet blocks a chemical pathway called dopamine. This combined action is highly unique and makes the medicine particularly effective at quieting overactive brain signals, helping to relieve severe anxiety, agitation, and extreme mood disturbances.
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Alcohol

Unsafe

Alcohol should be avoided while on treatment with Auxadep-50 Tablet as it can affect you much more and may make you feel more depressed.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy inform your doctor before taking Auxadep-50 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before receiving Auxadep-50 Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Auxadep-50 Tablet may cause drowsiness and impair your concentration. Hence, it is advised not to drive or operate machines while on treatment with Auxadep-50 Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Auxadep-50 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Auxadep-50 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Auxadep-50 Tablet is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

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Heart

Caution

Auxadep-50 Tablet should be avoided if you have heart problems, especially a history of heart attack or arrhythmias. It may cause serious cardiac side effects like QTc prolongation, tachycardia, or sudden death. Always consult your doctor for safer alternatives.

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Geriatrics

Caution

Auxadep-50 Tablet should be used with caution in geriatric patients due to increased sensitivity to side effects like dizziness, confusion, and heart rhythm changes. Close medical supervision is essential to ensure safe use.

What if I have taken an overdose of Auxadep-50 Tablet

In case of an accidental overdose, seek immediate emergency medical attention. Symptoms of an overdose may include extreme drowsiness, confusion, rapid heart rate, severe muscle shaking, or fainting.

Diet & Lifestyle Advise

  • Drink plenty of fluids and consume high-fibre foods, such as fresh fruits, vegetables, and whole grains, to help prevent constipation caused by this medicine.
  • Sip water, suck on ice chips, or chew sugar-free gum to relieve dry mouth symptoms.
  • Completely avoid alcohol while taking this medicine, as it can worsen sedation and dizziness.
  • Stand up slowly from a sitting or lying position to prevent dizziness and reduce your risk of falling.
  • Establish a consistent bedtime routine to support healthy sleep habits, which can aid your recovery from depression.
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How Soon It Starts Working

The time required for Auxadep-50 Tablet to start to work: The onset time of Auxadep-50 Tablet has not been clinically established. The time for which the effects of Auxadep-50 Tablet last: The duration of Auxadep-50 Tablet ’s effect is clinically not established.

What if you forget to take Auxadep-50 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Auxadep-50 Tablet tablets at room temperature, ideally between 68°F and 77°F (20°C to 25°C).

Drug Warnings

  • Do not stop taking Auxadep-50 Tablet suddenly, as this can cause withdrawal symptoms like headache, nausea, or a general feeling of discomfort.
  • Wear sunscreen and protective clothing when outdoors, as this medication can make your skin more sensitive to sunlight.
  • Do not drive, operate machinery, or perform hazardous activities until you are certain how this medicine affects your alertness.
  • Ask family members or close friends to help monitor you for sudden changes in mood, worsening depression, or unusual behaviors, especially during the first few weeks of treatment.
  • Inform your dentist, surgeon, or emergency room physician that you are taking Auxadep-50 Tablet before undergoing any medical procedures or surgeries.

Drug-Drug Interactions

verifiedApollotooltip
  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine if you have taken an MAOI antidepressant within the last 14 days, as combining them can cause dangerously high blood pressure or a life-threatening brain reaction.
  • Sedatives and Sleep Medicines: Taking this medication with other drugs that cause drowsiness, such as sleeping pills, opioid pain relievers, or muscle relaxants, can cause extreme sedation and slow breathing.
  • Blood Pressure Medications: Auxadep-50 Tablet may interfere with how certain blood pressure medications work, potentially reducing their effectiveness.
AmoxapineTranylcypromine
Critical
AmoxapineMetoclopramide
Critical

Drug-Drug Interactions

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AmoxapineTranylcypromine
Critical
How does the drug interact with Auxadep-50 Tablet:
Taking tranylcypromine with Auxadep-50 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Auxadep-50 Tablet with Tranylcypromine is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
AmoxapineMetoclopramide
Critical
How does the drug interact with Auxadep-50 Tablet:
Co-administration of Metoclopramide with Auxadep-50 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Auxadep-50 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmoxapineZiprasidone
Critical
How does the drug interact with Auxadep-50 Tablet:
Co-administration of Auxadep-50 Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Auxadep-50 Tablet but can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmoxapineSafinamide
Critical
How does the drug interact with Auxadep-50 Tablet:
Taking Safinamide with Auxadep-50 Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Auxadep-50 Tablet is not recommended, as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
AmoxapineBupropion
Severe
How does the drug interact with Auxadep-50 Tablet:
Taking bupropion with Auxadep-50 Tablet may raise the chance of seizures(fits), which can happen with either medicine. Furthermore, bupropion can raise Auxadep-50 Tablet levels in the blood, which may exacerbate other adverse effects.

How to manage the interaction:
Co- administration of bupropion along with Auxadep-50 Tablet can possibly lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
AmoxapineTetrabenazine
Severe
How does the drug interact with Auxadep-50 Tablet:
The combined use of Tetrabenazine and Auxadep-50 Tablet can increase the risk of an irregular heart rhythm and the severity of side effects associated with Tetrabenazine.

How to manage the interaction:
Co-administration of Tetrabenazine and Auxadep-50 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, fever, heat intolerance, excessive sweating, stiffness, difficulty moving or swallowing, sudden dizziness, lightheadedness, fainting, and fast or pounding heartbeats, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
AmoxapineMoxifloxacin
Severe
How does the drug interact with Auxadep-50 Tablet:
Using Moxifloxacin together with Auxadep-50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Moxifloxacin with Auxadep-50 Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, irregular heart rhythm, or difficulty breathing, it is important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
AmoxapineTrazodone
Severe
How does the drug interact with Auxadep-50 Tablet:
Taking Trazodone with Auxadep-50 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Co-administration of Trazodone with Auxadep-50 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience confusion, seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, tremor(shaking of hands & legs), incoordination, stomach pain, nausea, vomiting, and diarrhea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
AmoxapineVilazodone
Severe
How does the drug interact with Auxadep-50 Tablet:
When Vilazodone is taken with Auxadep-50 Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Auxadep-50 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
AmoxapineVenlafaxine
Severe
How does the drug interact with Auxadep-50 Tablet:
When venlafaxine is combined with Auxadep-50 Tablet, can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Venlafaxine and Auxadep-50 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Consuming grapefruit products may alter how your body breaks down this medicine, potentially increasing the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

It is not known whether Auxadep-50 Tablet is completely safe during pregnancy or while breastfeeding. It should only be used if your doctor believes the benefits outweigh the potential risks. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this medicine.
No, you should avoid alcohol while taking this medicine. Alcohol can significantly increase drowsiness, dizziness, and confusion, and it can also make your depression symptoms worse. Talk to your doctor or pharmacist if you have concerns.
Yes, some patients experience an increased appetite and subsequent weight gain while taking this medication. Maintaining a balanced diet and exercising regularly can help manage this side effect. Talk to your doctor if you experience significant changes in your weight.
No, it is advised not to stop taking Auxadep-50 Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.
Yes, drowsiness is a very common side effect, especially when you first start taking the medicine. Your doctor may recommend taking your dose at bedtime to help manage this. Avoid driving if you feel sleepy, and talk to your doctor if the sleepiness does not improve.
Yes, this medication can affect your heart rhythm and heart rate, particularly if you already have a heart condition. If you experience a very fast or irregular heartbeat, seek medical attention immediately. Talk to your doctor before starting this medicine if you have any heart issues.
Dry mouth is a common side effect of this class of medication. You can manage this by sipping water throughout the day, chewing sugar-free gum, or sucking on ice chips. If the dry mouth is severe or causes dental issues, talk to your doctor or pharmacist.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Navi Mumbai, 400705, Vishnu Bhokya Bhoir Marg, Sector 23, Juinagar, S.No.1, P.No. 62, Shri Sai Krishna Kunj Apt
Other Info - AUX0067

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