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  3. Axcelto-20 Tablet 14's

Axcelto-20 Tablet 14's, Pack of 14 TabletS
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Axcelto-20 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. It contains Rivaroxaban, which works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. You may experience bleeding, anemia (low number of red blood cells), and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

RIVAROXABAN-20MG

Manufacturer/Marketer :

Akcent Healthcare India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Axcelto-20 Tablet

Axcelto-20 Tablet belongs to a class of drugs known as anticoagulants or blood thinner. Axcelto-20 Tablet is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Axcelto-20 Tablet contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Take Axcelto-20 Tablet as prescribed. You are advised to take Axcelto-20 Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anemia (low number of red blood cells), and nausea. Most of these side effects of Axcelto-20 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Axcelto-20 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Axcelto-20 Tablet . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Axcelto-20 Tablet . Talk to your doctor immediately if you are pregnant or breastfeeding.

Uses of Axcelto-20 Tablet

Prevention of blood clot

Directions for Use

Take Axcelto-20 Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Axcelto-20 Tablet belongs to a class of drugs known as anticoagulants or blood thinner. Axcelto-20 Tablet is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Axcelto-20 Tablet works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

How Axcelto-20 Tablet Works

Axcelto-20 Tablet contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Axcelto-20 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Regularly exercise and have a balanced diet to maintain a healthy weight.
  • Eat lot of fruits and vegetables (minimum 5 servings/day).
  • Include vitamin K-rich foods for stable anticoagulation control.
  • Limit red and processed meats.
  • Avoid smoking and consumption of alcohol.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Avoid massaging the bruise, as this might worsen the damage to the injured tissue.
  • Resting the affected area helps prevent more injury and aids healing.
  • Place a cloth-wrapped ice pack or cold compress on the affected area for 10 to 15 minutes.
  • If the bruise is extensive, severe, or accompanied by other symptoms like warmth, redness, or swelling, get medical help.

What if I have taken an overdose of Axcelto-20 Tablet

Do not take more than the prescribed dose of Axcelto-20 Tablet as it may cause overdose. The symptoms of overdose include bloody/black/tarry stools, unusual bleeding or bruising, blood in urine and coughing up or vomiting blood or material that looks like coffee grounds. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Axcelto-20 Tablet should be used with caution in children. Prolonged use of Axcelto-20 Tablet may cause hair loss. Regular blood tests are recommended while taking Axcelto-20 Tablet to check the time taken for your blood to clot and the level of platelets (blood cells). If you are known to be allergic to Axcelto-20 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Axcelto-20 Tablet . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Axcelto-20 Tablet . Talk to your doctor immediately if you are pregnant or breastfeeding.

Drug-Drug Interactions

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RivaroxabanDiclofenac
Severe
RivaroxabanConivaptan
Severe

Drug-Drug Interactions

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RivaroxabanDiclofenac
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of Axcelto-20 Tablet together with Diclofenac may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of Diclofenac and Axcelto-20 Tablet can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanConivaptan
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of Conivaptan and Axcelto-20 Tablet can increase the blood levels of Axcelto-20 Tablet and increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Conivaptan and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanPhenytoin
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of phenytoin and Axcelto-20 Tablet may reduce the blood levels of Axcelto-20 Tablet, which may increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of phenytoin and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by a doctor. consult the doctor immediately for any queries. Do not stop using any medications without a doctor's advice.
RivaroxabanPiroxicam
Severe
How does the drug interact with Axcelto-20 Tablet:
Coadministration of piroxicam and Axcelto-20 Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of piroxicam and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanCobicistat
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of Cobicistat and Axcelto-20 Tablet can increase the blood levels of Axcelto-20 Tablet and increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Clobicistat and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanClopidogrel
Severe
How does the drug interact with Axcelto-20 Tablet:
Coadministration of Clopidogrel with Axcelto-20 Tablet increases the risk of severe bleeding due to the additive effect.

How to manage the interaction:
Although taking clopidogrel with Axcelto-20 Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
RivaroxabanAspirin
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of Aspirin and Axcelto-20 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Although Co-administration of Aspirin and Axcelto-20 Tablet can lead to an interaction, they can be taken together if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
RivaroxabanBivalirudin
Severe
How does the drug interact with Axcelto-20 Tablet:
Co-administration of Bivalirudin and Axcelto-20 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of bivalirudin and Axcelto-20 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanItraconazole
Severe
How does the drug interact with Axcelto-20 Tablet:
Coadministration of Itraconazole and Axcelto-20 Tablet may significantly increase the blood levels of Axcelto-20 Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Itraconazole and Axcelto-20 Tablet may interact, but if a doctor prescribes them, you can still use them. If you have dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, a severe headache, weakness, or any of these symptoms, consult a doctor. Never discontinue taking a medication without consulting a doctor.
RivaroxabanNaproxen
Severe
How does the drug interact with Axcelto-20 Tablet:
Coadministration of Naproxen and Axcelto-20 Tablet may increase the risk or severity of bleeding problems.

How to manage the interaction:
There may be a possible interaction between Naproxen and Axcelto-20 Tablet, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.

  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Axcelto-20 Tablet and lead to unwanted side effects. Hence try to avoid these juices while taking Axcelto-20 Tablet .

  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Axcelto-20 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Axcelto-20 Tablet as it may increase the risk of bleeding.

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Pregnancy

Caution

Tell your doctor before using Axcelto-20 Tablet because it may cause harmful effects. So, only use in that condition when a doctor is prescribed.

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Breast Feeding

Caution

Axcelto-20 Tablet may pass into breast milk. Therefore consult your doctor.

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Driving

Safe if prescribed

Axcelto-20 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Axcelto-20 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Axcelto-20 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Axcelto-20 Tablet is not approved for children. Therefore Axcelto-20 Tablet is not safe for children.

Have a query?

FAQs

Axcelto-20 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation.

No, you are not recommended to stop taking Axcelto-20 Tablet without consulting your doctor to worsen the condition. Therefore, take Axcelto-20 Tablet for as long as your doctor has prescribed it.

No, Axcelto-20 Tablet is not expected to cause weight gain. If you notice unexpected weight gain and think it is because of this Axcelto-20 Tablet , immediately consult your doctor and inform him about it.

Axcelto-20 Tablet has many beneficial effects, but it has the ability to make you bleed more than normal. Even with minor injuries as it decreases your ability to blood clotting. Sometimes Axcelto-20 Tablet may cause severe bleeding that may be dangerous and may require urgent medical care. This risk may be increased in people taking Axcelto-20 Tablet along with other blood thinner medicines.

Avoid taking grapefruit and grapefruit juice while taking Axcelto-20 Tablet , and it contains compounds that slow down the metabolism of Axcelto-20 Tablet and increase the activity leading to bleeding.

It is not known that Axcelto-20 Tablet causes hair loss. Kindly contact your doctor.

Axcelto-20 Tablet is a type of medicine known as an anticoagulant. Axcelto-20 Tablet works by stopping a clotting factor called factor Xa from working. This thins your blood, so it takes longer to clot.

You should take Axcelto-20 Tablet just after a meal or snack, or as advised by the doctor. It is important to take it with food to help your body absorb the entire dose.

The side effects of Axcelto-20 Tablet include bleeding, nausea and anemia (lack of blood). If these side effects persist or worsen, please consult your doctor.

Yes, Axcelto-20 Tablet is a blood thinner. It prevents the blood from clotting inside the blood vessels and also prevents the blood clots from recurring in the blood vessels.

Avoid taking grapefruit and grapefruit juice while taking Axcelto-20 Tablet as grapefruit contains compounds that slow down the Axcelto-20 Tablet metabolism and increase the activity leading to bleeding. However, if you are taking some other blood thinner like warfarin, you should avoid taking any food that increases the vitamin K activity or increases the blood clotting such as brussels, spinach, sprouts, broccoli, mustard greens, asparagus and green tea. But, the use of these food items is not restricted with Axcelto-20 Tablet .

Country of origin

India

Manufacturer/Marketer address

C B :- 385 A, Second Floor, Naria, Delhi - 110082, Near By Ring Road
Other Info - AXC0032

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jan 1, 2025 | 2:49 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202439s031,022406s035lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.6402.pdf
  3. https://www.nhs.uk/medicines/rivaroxaban/
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