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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Axioff TZ 50mg/150mg Suspension is used to treat various infections caused by bacteria and protozoans. It is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa, such as dysentery (inflammation of the colon) and malaria. It contains Ofloxacin and Tinidazole, which kill bacteria and parasites that cause infections and prevent the further spread of the infection. It may cause side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Axis Life Science Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Axioff TZ 50mg/150mg Suspension

Axioff TZ 50mg/150mg Suspension is a combination of medicines called 'antibiotics' primarily used to treat various infections caused by bacteria & protozoans. Axioff TZ 50mg/150mg Suspension is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa. Examples of infection caused by protozoa include dysentery (inflammation of the colon) and malaria. 

Axioff TZ 50mg/150mg Suspension is a combination of two antibiotics: Ofloxacin and Tinidazole. Ofloxacin helps treat and prevent a wide range of bacterial infections. It is bactericidal in nature, which means it works by killing bacteria that cause infections. It inhibits the processes of bacterial cells, ultimately destroying the bacteria and thereby preventing the further spread of the infection. Axioff TZ 50mg/150mg Suspension is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobic bacteria (that live without oxygen). On the other hand, Tinidazole kills parasites and anaerobic bacteria responsible for causing infections. It works by damaging their genetic material, called DNA. 

Axioff TZ 50mg/150mg Suspension should be taken in the dose and duration your doctor advises. It is recommended to take it with food and at a fixed time to achieve maximum effect. You may experience nausea, vomiting, stomach pain, loss of appetite, headache, and other symptoms. Most of these side effects of Axioff TZ 50mg/150mg Suspension do not require medical attention and typically resolve on their own over time. However, if the side effects are persistent, reach out to your doctor. Please consult your doctor immediately if you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath.

Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), a sleeping disorder or difficulty sleeping (sleep apnoea), severe liver disease, or a problem with alcohol or other prescription or recreational drugs. Inform your doctor if you plan to get pregnant, are pregnant, or are breastfeeding. Use of Axioff TZ 50mg/150mg Suspension is associated with an increased risk of tendinitis and tendon (tough tissue that connects muscle to bone) rupture in all ages. People taking Axioff TZ 50mg/150mg Suspension who are over 60 years are at high risk, especially those taking anti-allergic medicines like corticosteroid drugs. Axioff TZ 50mg/150mg Suspension is contraindicated in people with kidney/heart diseases and those who have had lung transplants; its use is not recommended.

Uses of Axioff TZ 50mg/150mg Suspension

Axioff TZ 50mg/150mg Suspension is used in the treatment of bacterial and protozoal infections. The detailed uses of Axioff TZ 50mg/150mg Suspension are as follows:

  • Treatment of Bacterial Infections: Axioff TZ 50mg/150mg Suspension is an antibiotic used to treat various bacterial infections, including respiratory, urinary tract, sexually transmitted infections, and skin infections.
  • Management of Gastrointestinal Infections: Axioff TZ 50mg/150mg Suspension helps to treat gastrointestinal infections caused by bacteria, relieving symptoms and promoting recovery.
  • Urinary tract Infections (UTIs): Axioff TZ 50mg/150mg Suspension can be used to treat urinary tract infections (UTIs) caused by susceptible bacteria.
  • Preventing Infection: Axioff TZ 50mg/150mg Suspension can be prescribed to prevent infections in patients undergoing surgery or those with weakened immune systems.

Have a query?

Directions for Use

  • Axioff TZ 50mg/150mg Suspension can be taken with or without food (excluding dairy products).
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Axioff TZ 50mg/150mg Suspension as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

Axioff TZ 50mg/150mg Suspension contains the antibiotics Ofloxacin and Tinidazole, which help treat and prevent a wide range of bacterial infections caused by Gram-negative bacteria, Gram-positive bacteria, and some anaerobic bacteria (that live without oxygen). It is bactericidal and works by killing bacteria that cause infections by preventing the formation of their cell walls, which are required for living. It also inhibits the repair of bacterial cells. Altogether, it kills the bacteria. Axioff TZ 50mg/150mg Suspension has the advantage of good penetration in most deep tissues and body fluids. Hence, it is also suitable for treating deep tissue and bone bacterial infections. 

How Axioff TZ 50mg/150mg Suspension Works

Axioff TZ 50mg/150mg Suspension is a combination of two antibiotics: Ofloxacin and Tinidazole. Ofloxacin helps treat and prevent a wide range of bacterial infections. It is bactericidal, which means it works by killing bacteria that cause infections. It inhibits the processes of bacterial cells, ultimately destroying the bacteria and thereby preventing the further spread of the infection. Axioff TZ 50mg/150mg Suspension is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobic bacteria (that live without oxygen). On the other hand, Tinidazole kills parasites and anaerobic bacteria responsible for causing infections. It works by damaging their genetic material, called DNA.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Axioff TZ 50mg/150mg Suspension

Do not take more than the prescribed dose of Axioff TZ 50mg/150mg Suspension as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not take Axioff TZ 50mg/150mg Suspension if you are allergic or have had a severe reaction to Ofloxacin or other quinolone or fluoroquinolone antibiotics such as Delafloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin, and Ciprofloxacin. Taking Axioff TZ 50mg/150mg Suspension may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or having a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune condition of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Axioff TZ 50mg/150mg Suspension may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with Axioff TZ 50mg/150mg Suspension. Additionally, exposure to sunlight should be avoided while taking Axioff TZ 50mg/150mg Suspension, as it may increase phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking Axioff TZ 50mg/150mg Suspension.

Diet & Lifestyle Advise

  • Avoid consuming many caffeine-containing products, such as coffee, tea, energy drinks, cola, and chocolate. Axioff TZ 50mg/150mg Suspension may increase nervousness, sleeplessness and anxiety caused by caffeine.
  • Probiotics should be taken after taking the full course of Axioff TZ 50mg/150mg Suspension to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods, such as yoghurt, cheese, sauerkraut, kombucha, and kimchi, can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains, such as whole-grain bread and brown rice, should be included in your diet. Make sure you drink plenty of water or other fluids daily while taking Axioff TZ 50mg/150mg Suspension.
  • Avoid alcoholic consumption with Axioff TZ 50mg/150mg Suspension as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Axioff TZ 50mg/150mg Suspension in fighting off infections.

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]
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Alcohol

Safe if prescribed

Alcohol is not known to cause any unpleasant side effects if taken along with Axioff TZ 50mg/150mg Suspension. But the intake of alcohol may damage your liver. So, consuming alcohol should be avoided with Axioff TZ 50mg/150mg Suspension.

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Pregnancy

Consult your doctor

Axioff TZ 50mg/150mg Suspension is a pregnancy Category C medicine. It is not known whether Axioff TZ 50mg/150mg Suspension will affect pregnancy. Hence, the intake of Axioff TZ 50mg/150mg Suspension should be avoided if you are pregnant or planning to become pregnant, as it may harm your foetus. Please consult your doctor.

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Breast Feeding

Consult your doctor

Axioff TZ 50mg/150mg Suspension is excreted in human milk. But the amount of Axioff TZ 50mg/150mg Suspension absorbed by the nursing infant is unknown. So, it may be unsafe to be used while breastfeeding. Please consult your doctor.

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Driving

Safe if prescribed

Axioff TZ 50mg/150mg Suspension can affect alertness and coordination. So, driving vehicles and operating machinery which requires concentration should be avoided.

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Liver

Consult your doctor

Axioff TZ 50mg/150mg Suspension to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may need to adjust the dose if you experience symptoms such as nausea, vomiting, loss of appetite, dark-coloured urine, or yellow discolouration of the skin or eyes.

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Kidney

Consult your doctor

Axioff TZ 50mg/150mg Suspension to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Axioff TZ 50mg/150mg Suspension is not recommended for use in children and adolescents below 18 years of age.

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Heart

This medicine is contraindicated in cardiac patients due to its adverse effects.

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Geriatrics

Consult your doctor

Axioff TZ 50mg/150mg Suspension should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Axioff TZ 50mg/150mg Suspension.

FAQs

Axioff TZ 50mg/150mg Suspension is used to treat various infections caused by bacteria and protozoans. It is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa. Examples of infection caused by protozoa include dysentery (inflammation of the colon) and malaria.

Not recommended. A patient with a transplanted kidney might be taking an immunosuppressive drug like cyclosporin, which is contraindicated with Axioff TZ 50mg/150mg Suspension failing to respond to the efficacy of the immunosuppressant drug. There are chances of rejection of the transplanted kidney in the patient, and, hence, it is not recommended to take Axioff TZ 50mg/150mg Suspension without a doctor's consultation.

Do not consume alcohol or alcohol-based products while taking Axioff TZ 50mg/150mg Suspension and for at least 3 days after your treatment commences. You may experience unpleasant side effects, such as a fast heartbeat, nausea, vomiting, sweating, and tingling under your skin.

Yes, after taking Axioff TZ 50mg/150mg Suspension, you may have diarrhoea. Axioff TZ 50mg/150mg Suspension is an antibiotic that kills or prevents bacterial growth, so some good intestinal bacteria that aid digestion might also get killed. Therefore, drink plenty of fluids and take probiotics to prevent excessive fluid loss from the body (dehydration).

It is advised not to take Axioff TZ 50mg/150mg Suspension with dairy products, as it may affect the absorption and efficacy of Axioff TZ 50mg/150mg Suspension. However, you can take it with a meal that includes these foods or drinks.

Axioff TZ 50mg/150mg Suspension can make your skin sensitive to sunlight, a condition known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In the event of an emergency, always wear sunscreen before going outdoors.

If you miss a dose of Axioff TZ 50mg/150mg Suspension, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Take Axioff TZ 50mg/150mg Suspension either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).

No, Axioff TZ 50mg/150mg Suspension should be taken as advised by the doctor in terms of dose and duration. If you take it in a dose greater than the recommended amount, it may cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor

Axioff TZ 50mg/150mg Suspension contains lactose, so tell your doctor if you are intolerant to some sugars.

It is advised to tell your doctor if you are already taking Warfarin before taking Axioff TZ 50mg/150mg Suspension as it can increase the time it takes for blood clotting.

Take Axioff TZ 50mg/150mg Suspension for as long as it is prescribed by your doctor. It is important to complete the full course of treatment for effective results.

Yes, Axioff TZ 50mg/150mg Suspension can cause dry mouth as a side effect. If you experience this, it's essential to stay hydrated by drinking plenty of water, taking regular sips throughout the day, and keeping a glass of water by your bedside at night.

You are recommended to take your doctor’s advice before taking Axioff TZ 50mg/150mg Suspension if you are breastfeeding, as Axioff TZ 50mg/150mg Suspension might enter breast milk and harm the unborn child.

Yes, a metallic taste may occur as a side effect of using Axioff TZ 50mg/150mg Suspension. This is usually temporary and can be managed by chewing sugar-free gum or mints, brushing your teeth after meals, and drinking plenty of water. If this side effect persists, consult your doctor.

The use of Axioff TZ 50mg/150mg Suspension is harmful for patients with a known allergy to ofloxacin or tinidazole. It should be avoided in patients with a history of tendinitis (inflammation of the tendons), or tendon rupture when using ofloxacin or any other medicine that belongs to the same group (quinolone group) of antimicrobial agents, and in patients with certain neurological disorders, kidney, or heart diseases.

Store the Axioff TZ 50mg/150mg Suspension in a cool, dry place at room temperature, away from direct light. Keep it out of reach of children.

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, please inform us if your symptoms are worsening while using this Axioff TZ 50mg/150mg Suspension.

No, you should not stop taking Axioff TZ 50mg/150mg Suspension even if you feel better. Complete the full course of treatment as prescribed by your doctor. If you stop using Axioff TZ 50mg/150mg Suspension too early, your infection may worsen.

Axioff TZ 50mg/150mg Suspension may affect alertness and coordination. Therefore, do not drive until you know how this medication affects you.

The common side effects of Axioff TZ 50mg/150mg Suspension are nausea, vomiting, stomach pain, loss of appetite, headache, and dry mouth. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Plot No. 29/4 Industrial Area, Phase 2 Chandigarh Chandigarh Ch 160002 In
Other Info - AX36962

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