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Aztel Trio 6.25 Tablet 15's

Aztel Trio 6.25 Tablet is used to treat high blood pressure (hypertension). It effectively lowers elevated blood pressure and supports better heart function. It is especially helpful for individuals with moderate to severe hypertension or those at high cardiovascular risk since it keeps blood pressure levels within normal ranges, lowering the risk of major problems like heart attack, stroke, heart failure, and kidney damage.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+CHLORTHALIDONE-6.25MG+TELMISARTAN-40MG

Manufacturer/Marketer :

Azkka Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Aztel Trio 6.25 Tablet

Aztel Trio 6.25 Tablet is a prescription oral medication used to treat high blood pressure (hypertension). Its primary medical purpose is to lower elevated blood pressure, which helps reduce the risk of life-threatening cardiovascular events like strokes and heart attacks. This medicine is typically prescribed when a single or dual-therapy blood pressure treatment is not enough to control your readings.

For the best results, you must take Aztel Trio 6.25 Tablet consistently every day at the same time, exactly as prescribed by your doctor. You can take this tablet with or without food, but keeping your routine consistent helps maintain stable blood pressure levels. Making positive lifestyle changes, such as eating a low-salt diet and exercising regularly, will significantly support the effectiveness of this medication.

While taking Aztel Trio 6.25 Tablet , some people may experience mild side effects like lightheadedness, mild headaches, or fluid retention in the ankles. However, if you experience more serious symptoms such as severe dizziness, fainting, or sudden muscle weakness, you must consult your doctor immediately. Do not ignore these signs, as they may indicate a need to adjust your treatment plan.

Before starting this medicine, talk to your doctor if you have a history of kidney disease, liver damage, diabetes, or severe dehydration. You should not take this medicine if you are pregnant, as it can cause serious harm or even death to an unborn baby. Women who are planning to become pregnant must discuss alternative blood pressure treatments with their healthcare provider. Patients with bilateral renal artery stenosis (narrowing of the arteries supplying both kidneys) should also avoid this medicine, as it can significantly worsen kidney function.

This medication can interact with other substances, including potassium supplements, certain pain relievers, and alcohol, which can cause your blood pressure to drop too low or harm your kidneys. If you are elderly, breastfeeding, or managing multiple chronic health conditions, consult your doctor to ensure this medicine is safe for your specific situation.

Uses of Aztel Trio 6.25 Tablet

Aztel Trio 6.25 Tablet is used in the treatment of Hypertension (high blood pressure). The detailed uses of Aztel Trio 6.25 Tablet are as follows:

  • Hypertension (high blood pressure): Aztel Trio 6.25 Tablet is used to treat high blood pressure when regular treatments have not successfully lowered it. It helps keep your blood pressure within a healthy target range to protect your long-term health.
  • Reduction of cardiovascular risk: By keeping your blood pressure consistently controlled, this medication helps lower your risk of experiencing severe heart complications, including heart attacks and strokes.

Key Benefits

Aztel Trio 6.25 Tablet helps lower and control high blood pressure, reducing the strain on your heart and blood vessels.

The following are the benefits of Aztel Trio 6.25 Tablet :

  • Helps lower and maintain healthy blood pressure levels.
  • Reduces the risk of heart attack, stroke, and other cardiovascular complications.
  • Supports healthy heart, kidney, and blood vessel function.
  • Promotes consistent blood pressure control throughout the day and night.
  • Provides convenient blood pressure management with three medicines in a single tablet.
Side effects of Aztel Trio 6.25 Tablet
  • Eat smaller meals and chew food thoroughly.
  • Try foods with softer textures.
  • If you have difficulty swallowing liquids, use thickener.
  • Learn new swallowing techniques from a speech and language therapist.
  • Avoid alcohol and caffeine as these may dry your throat and mouth making it more difficult to swallow.
  • Consider alternative forms of feeding, such as feeding tubes through nose or a hole into your stomach.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.

Directions for Use

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can alter how the medicine is absorbed into your body.
  • Take this medicine once daily, with or without food, preferably at the same time each day to build a habit and maintain steady drug levels.
  • Always follow your doctor's exact instructions regarding your treatment plan. Do not adjust your dose or stop taking the medicine without consulting them first.

How Aztel Trio 6.25 Tablet Works

Aztel Trio 6.25 Tablet works through the combined action of three distinct blood pressure-lowering agents that target different systems in your body: •Telmisartan: It is an angiotensin receptor blocker that blocks a natural hormone in your body that causes blood vessels to constrict, allowing your blood vessels to relax and widen so blood can flow more easily. • Amlodipine: It is a calcium channel blocker that relaxes the muscle cells in the walls of your blood vessels and heart, which further dilates the blood vessels and reduces the overall workload on your heart. • Chlorthalidone: It is a thiazide-like diuretic, commonly known as a water pill. It prompts your kidneys to eliminate excess water and salt from your bloodstream through your urine, reducing the amount of fluid your heart has to pump.
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Alcohol

Unsafe

It is unsafe to consume alcohol since alcohol consumption with Aztel Trio 6.25 Tablet may increase the risk of low blood pressure and cause adverse effects.

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Pregnancy

Unsafe

Aztel Trio 6.25 Tablet is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. Consult your doctor before taking Aztel Trio 6.25 Tablet if you plan to become pregnant or already pregnant.

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Breast Feeding

Consult your doctor

There is no evidence on how Aztel Trio 6.25 Tablet affects breastfeeding. Please consult your doctor before taking Aztel Trio 6.25 Tablet if you are breastfeeding.

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Driving

Caution

Aztel Trio 6.25 Tablet may cause side effects, which can affect your ability to concentrate and drive. Hence, do not drive or operate machinery until you are mentally alert.

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Liver

Caution

Aztel Trio 6.25 Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Aztel Trio 6.25 Tablet may affect kidney functioning. Hence, seek a doctor's advice before starting Aztel Trio 6.25 Tablet if you have kidney problems. However, it is not recommended for patients with severe renal impairment.

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Children

Unsafe

Safety and effectiveness of Aztel Trio 6.25 Tablet in paediatric patients have not been established.

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Heart

Safe if prescribed

Aztel Trio 6.25 Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Aztel Trio 6.25 Tablet should be used with caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Aztel Trio 6.25 Tablet

If you suspect an overdose, seek emergency medical assistance immediately. Symptoms of an overdose can include extreme dizziness, fainting, a dangerously slow or rapid heart rate, and severe weakness.

Diet & Lifestyle Advise

  • Eat a low-sodium diet: Limit your consumption of processed foods, canned soups, and table salt, as excessive sodium causes your body to retain water and raises your blood pressure.
  • Watch your potassium intake: Because this medicine affects how your kidneys manage minerals, talk to your doctor before using salt substitutes or significantly increasing your consumption of potassium-rich foods like bananas or leafy greens.
  • Stay hydrated: This medicine increases urination. Ensure you drink a steady amount of water throughout the day, but discuss your daily fluid goals with your doctor if you have heart or kidney issues.
  • Avoid smoking and limit alcohol: Smoking damages blood vessels, while alcohol can interact with your medicine to cause severe dizziness or dangerously low blood pressure.

Have a query?

How Soon It Starts Working

  • The time required for Aztel Trio 6.25 Tablet to start to work: The time required for Aztel Trio 6.25 Tablet to start to work is 2 hours after administration.
  • The time for which the effects of Aztel Trio 6.25 Tablet last: The effect of Aztel Trio 6.25 Tablet lasts for 24 to 72 hours.

What if you forget to take Aztel Trio 6.25 Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and resume your normal routine. Never take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Rise slowly: To avoid feeling dizzy or fainting, take your time when moving from a lying or sitting position to standing up.
  • Keep a blood pressure log: Monitor your blood pressure at home regularly and keep a written record to share with your doctor during your checkups.
  • Prepare for routine blood tests: Your doctor will schedule regular blood tests to monitor your kidney health and check your blood electrolyte levels (such as potassium and sodium).
  • Limit outdoor sun exposure: This medicine can make your skin more sensitive to sunlight. Wear protective clothing and apply sunscreen when spending time outdoors.
  • Avoid hazardous activities initially: Do not drive, operate machinery, or perform tasks requiring sharp focus until you know how this medicine affects your alertness.

Drug-Drug Interactions

verifiedApollotooltip
  • Other blood pressure medicines (e.g., enalapril, lisinopril, losartan): Taking Aztel Trio 6.25 Tablet with other blood pressure-lowering medications or water pills can cause your blood pressure to drop dangerously low.
  • Potassium supplements or potassium-sparing diuretics (e.g., potassium chloride, spironolactone): Combining Aztel Trio 6.25 Tablet with these supplements or water pills can cause high potassium levels in your blood, which can harm your heart.
  • Nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, naproxen): These pain relievers can reduce the effectiveness of Aztel Trio 6.25 Tablet and increase your risk of severe kidney damage.
  • Mood stabilisers (e.g., lithium): Aztel Trio 6.25 Tablet can increase the concentration of lithium in your body, raising the risk of severe lithium toxicity.
Telmisartan + Amlodipine + chlorthalidoneAliskiren
Critical
Telmisartan + Amlodipine + chlorthalidoneCisapride
Critical

Drug-Drug Interactions

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Telmisartan + Amlodipine + chlorthalidoneAliskiren
Critical
How does the drug interact with Aztel Trio 6.25 Tablet:
Co-administration of Aliskiren with Telmisartan, chlorthalidone and Amlodipine can increase the risk of kidney problems and other side effects.

How to manage the interaction:
Taking Telmisartan, chlorthalidone and Amlodipine with Aliskiren can possibly lead to an interaction, it can be taken if a doctor advices it. However, if you experience any symptoms like nausea, vomiting, weakness, confusion, tingling sensation in hands or feet, heaviness in legs, or slow or rapid heartrate. Do not discontinue any medications without consulting a doctor.
Telmisartan + Amlodipine + chlorthalidoneCisapride
Critical
How does the drug interact with Aztel Trio 6.25 Tablet:
Co-administration of Cisapride with Telmisartan, Amlodipine and chlorthalidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Cisapride with Telmisartan, Amlodipine and chlorthalidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Telmisartan + Amlodipine + chlorthalidoneCarbamazepine
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Administration of chlorthalidone, Telmisartan and amlodipine with carbamazepine together may reduce the blood levels of chlorthalidone, Telmisartan and amlodipine.

How to manage the interaction:
Although there is an interaction between chlorthalidone, Telmisartan and amlodipine with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor. Do not stop using any medications without talking to a doctor.
Telmisartan + Amlodipine + chlorthalidoneArsenic trioxide
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Co-administration of Arsenic trioxide with Telmisartan, Amlodipine and chlorthalidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Arsenic trioxide with Telmisartan, Amlodipine and chlorthalidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Telmisartan + Amlodipine + chlorthalidoneSimvastatin
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Taking Simvastatin with of Telmisartan, Amlodipine and chlorthalidone can increase the blood levels of Simvastatin.

How to manage the interaction:
Co-administration of Telmisartan, Amlodipine and chlorthalidone with Simvastatin can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, loss of hunger, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor. Do not stop using any medications without talking to a doctor.
Telmisartan + Amlodipine + chlorthalidoneCeritinib
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Co-administration of Ceritinib with Telmisartan, Amlodipine and chlorthalidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib with Telmisartan, Amlodipine and chlorthalidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Telmisartan + Amlodipine + chlorthalidoneRifabutin
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Co-administration of Rifabutin with Telmisartan, Amlodipine and chlorthalidone can decrease the blood levels of elmisartan, Amlodipine and chlorthalidone.

How to manage the interaction:
Although taking Rifabutin with Telmisartan, Amlodipine and chlorthalidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Telmisartan + Amlodipine + chlorthalidoneRifampicin
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Co-administration of Rifampicin with Telmisartan, Amlodipine and chlorthalidone can decrease the blood levels of elmisartan, Amlodipine and chlorthalidone.

How to manage the interaction:
Although taking Rifampicin with Telmisartan, Amlodipine and chlorthalidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Telmisartan + Amlodipine + chlorthalidoneLisinopril
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Taking Lisinopril with Telmisartan, Amlodipine and Chlorthalidone can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Lisinopril and Telmisartan, Amlodipine and Chlorthalidone may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
Telmisartan + Amlodipine + chlorthalidoneAmiodarone
Severe
How does the drug interact with Aztel Trio 6.25 Tablet:
Co-administration of Amiodarone with Telmisartan, Amlodipine and chlorthalidone can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Amiodarone with Telmisartan, Amlodipine and chlorthalidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, tiredness, confusion, muscle pain, nausea, vomiting or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while taking this medicine can worsen side effects like dizziness, lightheadedness, and fainting.
  • Grapefruit juice: Consuming grapefruit or grapefruit juice may increase medicine levels in your blood, which can increase side effects.
AMLODIPINE-5MG+CHLORTHALIDONE-6.25MG+TELMISARTAN-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+CHLORTHALIDONE-6.25MG+TELMISARTAN-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking potassium rich food while on the treatment with Amlodipine, chlorthalidone and telmisartan can increase the levels of potassium salt in blood which lead to experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Avoid or limit taking potassium rich food while on the treatment with Amlodipine, chlorthalidone and telmisartan.

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Aztel Trio 6.25 Tablet belongs to the anti-hypertensive drugs class, primarily used to treat high blood pressure (hypertension).
Aztel Trio 6.25 Tablet consists of anti-hypertensive/ blood pressure-lowering drugs: Amlodipine, Chlorthalidone, and Telmisartan. These medicines collectively lower the blood pressure by preventing the fluid build-up and widening the blood vessels, thus improving the blood supply and oxygen delivery to the heart.
Yes, Aztel Trio 6.25 Tablet can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.
Aztel Trio 6.25 Tablet may cause ankle swelling upon long-term use. Please try to keep your feet at an elevated level when sitting for long hours or sleeping. If the problem persists, consult your doctor and do as advised.
Aztel Trio 6.25 Tablet can cause high potassium levels in the blood, leading to hyperkalemia (high potassium levels in the blood). Hence, it is not recommended to use potassium supplements along with Aztel Trio 6.25 Tablet . However, consult your doctor if you have any concerns.
Do not stop using Aztel Trio 6.25 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Please inform your doctor if you are taking Aztel Trio 6.25 Tablet and need to undergo any surgery. Your doctor may ask you to stop using Aztel Trio 6.25 Tablet or prescribe any alternate medication because blood pressure may be further lowered if taken along with general anaesthesia.
Aztel Trio 6.25 Tablet is not recommended in pregnancy. It can affect and harm the developing baby. Consult your doctor before taking Aztel Trio 6.25 Tablet if you plan to become pregnant or are already pregnant.
Aztel Trio 6.25 Tablet can cause side effects like sleepiness, taste changes, ankle swelling, headache, dizziness, tiredness, and upset stomach. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist, please consult your doctor.
One of the active ingredients in Aztel Trio 6.25 Tablet is a diuretic (water pill). It is designed to help your body flush out excess water and salt through your urine, which helps lower your blood pressure. Talk to your doctor if this becomes unmanageable.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can interact with Aztel Trio 6.25 Tablet , causing your blood pressure to drop too low, which increases your risk of severe dizziness, headache, and fainting. Talk to your doctor.
You should avoid taking common pain relievers like ibuprofen or naproxen while on this medicine. These drugs can reduce the blood pressure-lowering effect of Aztel Trio 6.25 Tablet and put extra strain on your kidneys. Talk to your doctor or pharmacist for safe pain relief alternatives.
Yes, your doctor will periodically order blood tests to check your kidney function and monitor your blood electrolyte levels (such as potassium and sodium) to ensure the medication remains safe for you. Talk to your doctor.

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Reference

  1. Drugs.com Clinical Review Team. Amlodipine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Telmisartan Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Chlorthalidone Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. National Center for Biotechnology Information (NCBI). Amlodipine Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  5. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026] Check here
  6. Telmisartan+Amlodipine [Prescribing Information]. 2009. [Accessed on 06 May 2025] Check here
  7. Amlodipine besylate [Prescribing Information]. 2011. [Accessed on 06 May 2025]Check here

Country of origin

India

Manufacturer/Marketer address

403, Shikhar Complex, Mithakhali Six Roads, Ahmedabad- 380009 Gujarat, India.
Other Info - AZT0069

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