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compositionComposition:BILASTINE-20MG+MONTELUKAST-10MG
prescription
Prescription Medicine
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Bilarub-M Tablet is used to treat allergic conditions such as asthma, allergic rhinitis (hay fever), and exercise-induced breathing difficulties. It helps reduce inflammation and allergy symptoms like sneezing, runny nose, itching, and nasal congestion, improving overall breathing comfort. Bilarub-M Tablet contains two medicines: Montelukast and Bilastine. Montelukast reduces swelling, mucus, and tightness in the airways by blocking chemicals called leukotrienes. Bilastine blocks histamine, which causes allergy symptoms like sneezing, itching, and swelling. Together, they control both inflammation and allergic reactions to provide better relief. In some cases, this medicine may cause side effects such as nausea, vomiting, dryness in the mouth, diarrhoea, dizziness, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BILASTINE-20MG+MONTELUKAST-10MG

Manufacturer/Marketer :

Usk Health Care Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bilarub-M Tablet

Bilarub-M Tablet is a prescription medicine used to relieve the symptoms of seasonal and year-round allergies, especially when they are accompanied by asthma. It helps control allergic reactions by targeting two different pathways in your body that cause inflammation and airway swelling. This combination tablet provides effective, daily relief from sneezing, an itchy or runny nose, and breathing difficulties.

For the best results, you should take Bilarub-M Tablet consistently at the same time every day. It must be taken on an empty stomach—either one hour before or two hours after eating food or drinking fruit juice—as food significantly reduces how well the medicine is absorbed. Combining this treatment with simple lifestyle adjustments, like keeping your windows closed during high-pollen seasons, can help improve your overall symptom control.

While Bilarub-M Tablet is generally well-tolerated, some people may experience mild side effects such as drowsiness, headache, or dizziness. If you experience severe side effects, such as unusual mood changes, severe skin rashes, or swelling of the face, stop taking the medicine and consult your doctor immediately.

Before starting this medication, it is important to tell your doctor if you have a history of kidney issues, liver damage, or mental health conditions like depression. Do not take this if you have a known allergy to any of its active ingredients.

This medicine can interact with certain other treatments and substances; for example, taking it with antifungal medicines can increase the risk of side effects, while alcohol can make you feel more drowsy. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist before starting this medicine to ensure it is safe for you.
 

Uses of Bilarub-M Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Allergic rhinitis: Bilarub-M Tablet helps reduce swelling in the nasal passages, relieving symptoms like sneezing, a runny or blocked nose, and itchy eyes caused by seasonal or year-round allergies.
  • Allergic asthma: Bilarub-M Tablet helps prevent breathing difficulties, wheezing, and coughing in individuals who experience both asthma and nasal allergy symptoms.

Key Benefits

Bilarub-M Tablet provides the following benefits when used as prescribed:

  • Targets Allergy Triggers: This medicine helps you feel better by directly targeting the biological triggers of your allergies.
  • Relieves Allergy Symptoms: By blocking the substances that cause swelling and mucus production, Bilarub-M Tablet makes it easier to breathe and helps you go about your day without constant sneezing, congestion, or itching.
  • Improves Sleep: Another major benefit is improved sleep and daily productivity. Since allergy symptoms often worsen at night, managing them effectively helps you rest better, leaving you feeling more alert, active, and focused during the day.
     
Side effects of Bilarub-M Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

Directions for Use

  • Bilarub-M Tablet can be taken with or without food. However, avoid taking it with fruit juices, such as orange, apple, or grapefruit, as they may reduce its effectiveness.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Bilarub-M Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Bilarub-M Tablet Works

Bilarub-M Tablet is a combination medicine containing two active ingredients, bilastine and montelukast, which work in harmony to control your symptoms. The first active ingredient, bilastine, is an antihistamine. When your body encounters an allergen like pollen or dust, it releases a chemical called histamine, which causes itching, sneezing, and a runny nose. This medicine blocks histamine receptors, stopping these symptoms before they start. The second active ingredient, montelukast, is a leukotriene receptor antagonist. It works by blocking leukotrienes, which are chemicals that cause the airways in your lungs to swell and tighten. By blocking these chemicals, it reduces inflammation, opens up your airways, and makes breathing much easier.
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Alcohol

Caution

Avoid drinking alcohol while taking this medicine as it can worsen your side effects like drowsiness.

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Pregnancy

Consult your doctor

The safety of Bilarub-M Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Bilarub-M Tablet is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Avoid doing any work that needs complete attention, including driving, as this drug may make a person drowsy.

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Liver

Consult your doctor

Take Bilarub-M Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take Bilarub-M Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Bilarub-M Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

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Heart

Caution

Bilarub-M Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Bilarub-M Tablet .

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Geriatrics

Caution

Bilarub-M Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Bilarub-M Tablet .

What if I have taken an overdose of Bilarub-M Tablet

If you accidentally take more than the prescribed amount of Bilarub-M Tablet , seek immediate medical attention even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Avoid fruit juices: Do not drink grapefruit, orange, or apple juice within two hours of taking Bilarub-M Tablet , as they can significantly reduce how much medicine your body absorbs.
  • Track your triggers: Keep a journal to identify what triggers your allergy or asthma symptoms, such as pollen, pet dander, or dust mites, so you can minimize your exposure.
  • Keep indoor air clean: Use air purifiers with HEPA filters and keep windows closed during high-pollen seasons to reduce indoor allergens.
  • Stay hydrated: Drinking plenty of water helps thin out mucus in your airways, making it easier to breathe.
     
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How Soon It Starts Working

  • The time required for Bilarub-M Tablet to start to work: Bilarub-M Tablet ideally shows its action within 1 hour of administration.
  • The time for which the effects of Bilarub-M Tablet last: Bilarub-M Tablet effect lasts for 24 hours.

What if you forget to take Bilarub-M Tablet

If you miss a dose, take it as soon as you remember, provided it is not too close to your next scheduled dose. If it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store the tablets at room temperature, ideally below 30°C.

Drug Warnings

  • Take on an empty stomach: Food and fruit juices heavily interfere with how this medicine works. Always stick to the rule of taking it one hour before or two hours after eating.
  • Monitor your mood: Pay close attention to any sudden changes in your mood, thoughts, or behavior. If you feel unusually anxious, irritable, or depressed, contact your doctor immediately.
  • Be careful when driving: Since this medicine can cause drowsiness or dizziness in some people, avoid driving, operating machinery, or performing tasks that require full alertness until you know how it affects you.
  • Limit alcohol: Avoid drinking alcohol while taking Bilarub-M Tablet , as it can worsen drowsiness and impair your coordination.

Drug-Drug Interactions

verifiedApollotooltip

Some medicines may affect how Bilarub-M Tablet works or increase the risk of side effects:

  • Ketoconazole or Erythromycin: Taking these antifungal or antibiotic medications with Bilarub-M Tablet may increase the levels of the allergy medicine in your body, potentially raising the risk of side effects.
  • Rifampicin: This antibiotic may lower the levels of Bilarub-M Tablet in your body, making it less effective.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

The following foods and drinks may affect how Bilarub-M Tablet works or increase the risk of side effects:

  • Fruit Juices: Grapefruit, apple, and orange juice can greatly decrease the absorption of Bilarub-M Tablet , reducing its ability to treat your symptoms.
  • Food: Eating a meal right before or after taking this medicine reduces its bioavailability, making it less effective.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIALLERGIC]

FAQs

Bilarub-M Tablet is used to treat allergic conditions such as asthma, allergic rhinitis (hay fever), and exercise-induced breathing difficulties. It helps reduce inflammation and allergy symptoms like sneezing, runny nose, itching, and nasal congestion, improving overall breathing comfort.
Bilarub-M Tablet combines two drugs: Montelukast (leukotriene receptor antagonist) and Bilastine (antihistamine). Montelukast blocks the action of chemicals called leukotrienes released from the lungs, causing inflammation (swelling) and increased mucus production in the airways. Thereby reducing inflammation, mucus production, and narrowing in the airways. Bilastine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness.
You should avoid taking fruit juices like orange, apple or grapefruit with Bilarub-M Tablet as they may reduce the effectiveness of Bilarub-M Tablet .
Yes, Bilarub-M Tablet may cause drowsiness. It is not necessary for everyone taking Bilarub-M Tablet to experience this side effect. Therefore, avoid driving if you feel drowsy or dizzy after taking Bilarub-M Tablet .
Therapy with leukotriene receptor antagonists like Montelukast may worsen the symptoms of psychotic events in patients with a history of mental illness. Careful administration and monitoring are essential before taking Bilarub-M Tablet in patients with neuropsychiatric disorders. Please consult your doctor before taking Bilarub-M Tablet if you have been diagnosed or have a history of mental illness like depression, seizures (fits) etc.
Stopping Bilarub-M Tablet without consulting a doctor may cause drug withdrawal symptoms that can worsen allergies. It is better to ask the doctor even if you are feeling better, as sometimes the doctor prefers to lower the strength of the drug.
No, you should not take Bilarub-M Tablet with food. Food significantly reduces the absorption and effectiveness of this medicine. Take it at least one hour before or two hours after eating. Talk to your doctor or pharmacist if you have trouble scheduling your doses.
No, Bilarub-M Tablet is not a rescue inhaler and should not be used to treat a sudden, acute asthma attack. Always use your prescribed quick-relief inhaler for sudden breathing emergencies. Talk to your doctor about managing sudden symptoms.
It is highly recommended to avoid alcohol while taking Bilarub-M Tablet . Alcohol can increase the risk of drowsiness, dizziness, and impaired concentration. Talk to your doctor or pharmacist if you have questions about alcohol use.
If you notice any unusual changes in your mood, behavior, or sleep patterns, such as anxiety, aggression, or depression, stop taking the medicine and contact your doctor immediately. Talk to your doctor to find a safer alternative.
The safety of this medicine during pregnancy is not fully established. If you are pregnant, planning to become pregnant, or breastfeeding, you should talk to your doctor or pharmacist to weigh the benefits against potential risks before taking this medicine.
You should not take other antihistamines with Bilarub-M Tablet unless specifically advised by your doctor, as this can increase the risk of side effects like severe drowsiness. Talk to your doctor or pharmacist before combining any over-the-counter allergy medicines.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Ilaxten+20+Mg+Tablets Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.1243 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Allergies - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Montelukast sodium [Prescribing Information]. 2012. [Accessed on 14 Aug. 2024]Check here
  5. Montelukast and bilastin [Patient leaflet]. 2024. [Accessed on 19 Feb. 2025]Check here
  6. Nutra Respiro [Product Information]. [Accessed on 14 Aug. 2024]Check here
  7. Centaurpharma: Bilastine and montelukast [Prescribing Information]. 2021. [Accessed on 20 Feb. 2025]Check here

Country of origin

India
Other Info - BIL0302
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