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  3. Binaprex ER 250 Tablet 10's

Binaprex ER 250 Tablet 10's, Pack of 10 TABLETS
Binaprex ER 250 Tablet 10's, Pack of 10 TABLETS
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bhim UPI
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Binaprex ER 250 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and prevent migraines. It contains Divalproex, which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. It helps block nerve transmission across the brain and provides a calming effect. In some cases, it may cause side effects such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DIVALPROEX-250MG

Manufacturer/Marketer :

Cenesys Care India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Binaprex ER 250 Tablet

Binaprex ER 250 Tablet is used to treat epilepsy/seizures/fits. Additionally, Binaprex ER 250 Tablet is also used to treat manic episodes associated with bipolar disorder and prevent migraines. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Binaprex ER 250 Tablet contains 'Divalproex', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Binaprex ER 250 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder. 

Take Binaprex ER 250 Tablet with or without food. Depending on your medical condition, you are advised to take Binaprex ER 250 Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects, such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Binaprex ER 250 Tablet without consulting your doctor to avoid worsening seizures. Do not take Binaprex ER 250 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Binaprex ER 250 Tablet . Consult your doctor before taking Binaprex ER 250 Tablet if you are breastfeeding. Avoid driving or operating machinery as Binaprex ER 250 Tablet causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Binaprex ER 250 Tablet as it could lead to increased dizziness. Care should be taken while giving Binaprex ER 250 Tablet to children below two years as there is a higher risk of liver intoxication during the first 6months of treatment. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Binaprex ER 250 Tablet

Treatment of Epilepsy, bipolar disorder, migraine.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush it.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.Sprinkle capsule: Swallow it as a whole with water or sprinkle the capsule contents on food and consume.

Medicinal Benefits

Binaprex ER 250 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Binaprex ER 250 Tablet is used to treat epilepsy/seizures/fits. Also, Binaprex ER 250 Tablet is used to treat mood disorders and prevent migraine headaches. Binaprex ER 250 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures. Binaprex ER 250 Tablet treats mood disorders by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Binaprex ER 250 Tablet prevents migraine headaches by limiting the transmission of nerve pain. Binaprex ER 250 Tablet is used alone or in combination to treat simple, complex partial, and complex absence seizures. Binaprex ER 250 Tablet is used in combination to treat multiple seizures, such as absence seizures.

How Binaprex ER 250 Tablet Works

Binaprex ER 250 Tablet contains 'Divalproex', which decreases the brain's excessive and abnormal nerve activity. Thereby helping in controlling seizures. Binaprex ER 250 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thereby helping treat bipolar disorder.

Storage

Store in a cool and dry place away from sunlight
Side effects of Binaprex ER 250 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Binaprex ER 250 Tablet

Do not take more than the prescribed dose of Binaprex ER 250 Tablet as it may cause overdose resulting in heart block, excess sleepiness and deep coma. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Binaprex ER 250 Tablet if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders. Inform your doctor before taking Binaprex ER 250 Tablet if you have pancreatitis, blood problems or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendencies while taking Binaprex ER 250 Tablet . Binaprex ER 250 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems. Please do not stop taking Binaprex ER 250 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Binaprex ER 250 Tablet if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Binaprex ER 250 Tablet . Consult your doctor before taking Binaprex ER 250 Tablet if you are breastfeeding. Avoid driving or operating machinery as Binaprex ER 250 Tablet causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Binaprex ER 250 Tablet as it could lead to increased dizziness. Care should be taken while giving Binaprex ER 250 Tablet to children below 2 years as there is a higher risk of liver intoxication during the first six months of treatment.

Drug-Drug Interactions

verifiedApollotooltip
DivalproexGlycerol phenylbutyrate
Critical
DivalproexMeropenem
Severe

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Binaprex ER 250 Tablet:
Coadministration of Glycerol phenylbutyrate and Binaprex ER 250 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Binaprex ER 250 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexMeropenem
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Binaprex ER 250 Tablet and Meropenem can reduce the blood levels of Binaprex ER 250 Tablet sodium.

How to manage the interaction:
Co-administration of Binaprex ER 250 Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
DivalproexSodium oxybate
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Sodium oxybate and Binaprex ER 250 Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Binaprex ER 250 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexSodium phenylbutyrate
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Sodium phenylbutyrate and Binaprex ER 250 Tablet can increase ammonia levels in the blood and is generally not recommended for patients with urea cycle disorders.

How to manage the interaction:
Co-administration of Binaprex ER 250 Tablet with Sodium phenylbutyrate can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
DivalproexBexarotene
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Binaprex ER 250 Tablet and Bexarotene can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Binaprex ER 250 Tablet and Bexarotene can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, or stomach cramps, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexLomitapide
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Binaprex ER 250 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Binaprex ER 250 Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
DivalproexKetoconazole
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Coadministration of Ketoconazole and Binaprex ER 250 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Binaprex ER 250 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexKetamine
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Binaprex ER 250 Tablet and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Binaprex ER 250 Tablet and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Binaprex ER 250 Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Binaprex ER 250 Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
DivalproexTeriflunomide
Severe
How does the drug interact with Binaprex ER 250 Tablet:
Co-administration of Binaprex ER 250 Tablet and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Binaprex ER 250 Tablet and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.

  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan, help those around you know what to do.

  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Binaprex ER 250 Tablet Substitute

Substitutes safety advice

  • Divaa-OD 250 Tablet 10's

    by Others

    ₹10.58per tablet

  • Valance OD 250 mg Tablet 15's

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    ₹12.33per tablet

  • Divalgress-ER 250 Tablet 10's

    by AYUR

    ₹7.38per tablet

  • Depakote XR 250 Tablet 15's

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    ₹11.73per tablet

  • Divalex OD 250 mg Tablet 10's

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    ₹10.08per tablet

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Binaprex ER 250 Tablet as it may cause increased dizziness.

bannner image

Pregnancy

Unsafe

Binaprex ER 250 Tablet belongs to pregnancy category D. Avoid taking Binaprex ER 250 Tablet if you are pregnant as it could lead to serious birth defects. Consult your doctor for further advice.

bannner image

Breast Feeding

Caution

Binaprex ER 250 Tablet may pass into breastmilk. Consult your doctor before taking Binaprex ER 250 Tablet if you are breastfeeding.

bannner image

Driving

Unsafe

Binaprex ER 250 Tablet causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery.

bannner image

Liver

Caution

Binaprex ER 250 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Binaprex ER 250 Tablet can be given to children if prescribed by the doctor. The doctor will adjust the dose depending on the child's body weight. Care should be taken in children below two years as they are at a higher risk of liver toxicity.

Have a query?

FAQs

Binaprex ER 250 Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat manic episodes associated with bipolar disorder and prevent migraines.

Binaprex ER 250 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

Binaprex ER 250 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Binaprex ER 250 Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Binaprex ER 250 Tablet may interact with aspirin and cause abnormal side-effects. So, it is recommended to take any medication along with Binaprex ER 250 Tablet only after consulting a doctor.

Binaprex ER 250 Tablet may improve the symptoms of depression. However, do not use it without consulting a doctor as it may also cause mood disturbances and suicidal thoughts in some patients.

Do not discontinue Binaprex ER 250 Tablet without consulting your doctor. To treat your condition effectually, continue taking Binaprex ER 250 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Binaprex ER 250 Tablet ; your doctor will gradually reduce the dose to avoid worsening seizures.

Before taking Binaprex ER 250 Tablet , certain laboratory tests are recommended. These include a Complete Blood Count (CBC), liver function tests (LFTs), kidney function tests, blood urea nitrogen (BUN) and creatinine levels, and a pregnancy test for women of childbearing age. Additionally, blood glucose levels should be checked for patients with diabetes or at risk of developing diabetes. Platelet count and coagulation tests (PT/INR/APTT) are also recommended. Please note that this list may not be exhaustive, and additional tests or monitoring may be necessary based on individual circumstances.

Binaprex ER 250 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Binaprex ER 250 Tablet .

Topiramate (anticonvulsant) should not be taken along with Binaprex ER 250 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

It's crucial to consult with your doctor before discontinuing Binaprex ER 250 Tablet . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Binaprex ER 250 Tablet is also used to treat mood disorders. It treats mood disorders by increasing the amount of a chemical substance called GABA, which helps block nerve transmission across the brain and provides a calming effect.

Binaprex ER 250 Tablet can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, you must talk to your doctor.

Yes, Binaprex ER 250 Tablet can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Binaprex ER 250 Tablet , it's essential to consult with your doctor.

Yes, Binaprex ER 250 Tablet can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Binaprex ER 250 Tablet , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Binaprex ER 250 Tablet as it may cause increased dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Binaprex ER 250 Tablet , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

Overdose of Binaprex ER 250 Tablet can be a severe medical emergency. If you or someone you know has taken an overdose of Binaprex ER 250 Tablet , it's crucial to seek immediate medical attention.

Binaprex ER 250 Tablet can be taken with or without food. However, it is recommended to take it with food to reduce stomach upset and improve absorption. Food can help buffer any potential stomach irritation and enhance the body's absorption of the medication.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

No 15 A, Velachery Road, Saidapet, Chennai - 600015
Other Info - BIN0053

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jan 1, 2025 | 2:49 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=e26005ef-77f0-4393-a2dc-b5fe460cead8&type=display
  3. https://www.drugs.com/mtm/divalproex-sodium.html
  4. https://www.depakote.com/depakote-formulations
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