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Biodronate 60 mg Injection is used in the treatment of Hypercalcemia in Malignancy, Paget's disease, and Osteolytic bone metastases of breast cancer. It contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, bone strength and bone health.
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About Biodronate 60 mg Injection
Biodronate 60 mg Injection is a hypocalcemic agent that belongs to the bisphosphonates class. It is mainly used in lowering blood calcium levels and bone metastases/lesions in cancer patients. Besides this, it is also used to treat mild to moderate Paget's disease. Hypercalcemia (increased calcium levels) is a condition in which the calcium level in your blood is elevated due to certain conditions. Paget’s disease is a serious condition of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak, and brittle.
Biodronate 60 mg Injection contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, bone strength and bone health.
Biodronate 60 mg Injection may cause certain side effects such as injection site reactions, stomach pain, loss of appetite, nausea, vomiting, fever, headache, dizziness, mouth sores, constipation, and cough. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist for a longer period, please consult your doctor. Biodronate 60 mg Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.
Biodronate 60 mg Injection should be avoided if you are allergic to it or any other components present in it. Before receiving Biodronate 60 mg Injection, let your doctor know about all your medical conditions, sensitivities, and medications you are using to rule out any interactions. Biodronate 60 mg Injection should be used under caution if you have/had kidney disease, liver problems, bone disorders, musculoskeletal pain, and high blood pressure. Biodronate 60 mg Injection is not recommended for use in pregnant women due to foetal harm, and whether this medicine can be used for breastfeeding mothers is unknown. Hence, inform your doctor if you are pregnant or are breastfeeding before receiving Biodronate 60 mg Injection. This medicine is not recommended for use in children as safety and efficacy have not been established.
Uses of Biodronate 60 mg Injection
Biodronate 60 mg Injection is used in the treatment and management of conditions related to abnormal bone metabolism. The detailed uses of Biodronate 60 mg Injection are as follows:

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Directions for Use
Medicinal Benefits
Biodronate 60 mg Injection contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, strength, and health.
How Biodronate 60 mg Injection Works
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What if I have taken an overdose of Biodronate 60 mg Injection
Drug Warnings
Biodronate 60 mg Injection should be avoided if you are allergic to it or any other components present in it. Before receiving Biodronate 60 mg Injection, let your doctor know about all your medical conditions, sensitivities, and medication history you are using to rule out any interactions. Biodronate 60 mg Injection should be used under caution if you have/had kidney disease, liver problems, bone disorders, musculoskeletal pain, and high blood pressure. Biodronate 60 mg Injection is not recommended for use in pregnant women due to foetal harm, and whether this medicine can be used for breastfeeding mothers is unknown. Hence, inform your doctor if you are pregnant or are breastfeeding before receiving Biodronate 60 mg Injection. This medicine is not recommended for use in children as safety and efficacy have not been established.
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Diet & Lifestyle Advise
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Therapeutic Class

Alcohol
Unsafe
Consuming alcohol while on treatment with Biodronate 60 mg Injection is not recommended as it may result in unpleasant side effects or make you more susceptible to the effects of alcohol.
Pregnancy
Unsafe
It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Biodronate 60 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
Caution
If you are breastfeeding, inform your doctor before receiving Biodronate 60 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
Unsafe
Biodronate 60 mg Injection will be administered in the hospital setting. Hence, avoid driving vehicles.
Liver
Caution
If you have a pre-existing or a history of liver disease, inform your doctor before receiving Biodronate 60 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
Caution
If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Biodronate 60 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Unsafe
Biodronate 60 mg Injection is not recommended for children as the safety and effectiveness have not been established.
Heart
Take Biodronate 60 mg Injection with caution, especially if you have a history of heart diseases/conditions. The dose may be adjusted by your doctor as required.
Geriatrics
Consult your doctor
Limited information available about the use of Biodronate 60 mg Injection in geriatric patients. Please consult your physician.
Biodronate 60 mg Injection is used to treat Hypercalcemia in Malignancy, Paget’s disease, and Osteolytic bone metastases of breast cancer.
Biodronate 60 mg Injection contains Pamidronate as an active ingredient, which works by inhibiting osteoclast bone resorption that causes bone breakdown.
Biodronate 60 mg Injection helps regulate the calcium level in the blood. This maintains bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damage bones becomes comparatively less.
Biodronate 60 mg Injection will be administrated by a healthcare professional such as a doctor or a nurse. Do not self-administer.
The frequency of Biodronate 60 mg Injection administration depends on the condition being treated. Therefore, follow your doctor's instructions for the best results.
Biodronate 60 mg Injection is not recommended for pregnant women as it may cause fetal harm. It is unknown whether Biodronate 60 mg Injection is excreted in human milk. Therefore, if you are a breastfeeding mother, please inform your doctor before taking Biodronate 60 mg Injection.
Yes, Biodronate 60 mg Injection may cause hair loss, but this is not a common side effect. If you experience hair loss while taking Biodronate 60 mg Injection, please inform your doctor.
Biodronate 60 mg Injection is safe if used under the supervision of a doctor. Follow your doctor’s instructions carefully and inform your doctor if you experience any side effects.
Maintain a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support your overall health. Try to consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers. Regular exercise like weight-bearing exercises are important for maintaining bone health. Smoking can weaken bones, and excessive alcohol consumption can interfere with bone health. It's best to quit smoking and limit alcohol intake. Please consult your doctor if you have any concerns.
The common side effects of Biodronate 60 mg Injection are injection site reactions, stomach pain, loss of appetite, nausea, vomiting, fever, headache, dizziness, mouth sores, constipation, and cough. If any of these side effects persist or worsen, please consult your doctor.
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