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  3. Bisobis A 2.5 Tablet 10's

Prescription drug
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Bisobis A 2.5 Tablet 10's, Pack of 10 TABLETS
Bisobis A 2.5 Tablet 10's, Pack of 10 TABLETS
Bisobis A 2.5 Tablet 10's, Pack of 10 TABLETS
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Extra 15% Off with Bank Offers

Composition :

AMLODIPINE-5MG + BISOPROLOL FUMARATE-2.5MG

Manufacturer/Marketer :

Corona Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bisobis A 2.5 Tablet

Bisobis A 2.5 Tablet is used to treat high blood pressure. It lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future.

Bisobis A 2.5 Tablet contains Amlodipine and Bisoprolol fumarate, which work by relaxing the blood vessels, reducing the workload on the heart, and making the heart more efficient at pumping blood throughout the body.

In some cases, Bisobis A 2.5 Tablet may cause side effects like headache, dizziness, palpitations, abdominal pain, ankle swelling, and oedema. Most of these side effects do not require medical attention and will resolve over time. However, talk to your doctor if you experience these side effects persistently.

Avoid taking Bisobis A 2.5 Tablet if you are allergic to any of its components. Consult your doctor before starting Bisobis A 2.5 Tablet if you are pregnant or breastfeeding. Bisobis A 2.5 Tablet is not recommended for children below 18 years, as the safety and effectiveness have not been established.

Uses of Bisobis A 2.5 Tablet

Bisobis A 2.5 Tablet is used in the treatment of High blood pressure (hypertension). The detailed uses of Bisobis A 2.5 Tablet are as follows:

  • Hypertension Treatment: Bisobis A 2.5 Tablet is used to treat high blood pressure by relaxing blood vessels and reducing heart rate.
  • Angina Management: Bisobis A 2.5 Tablet helps to manage chest pain (angina) by improving blood flow to the heart and reducing the heart's workload.
  • Cardiovascular Protection: Bisobis A 2.5 Tablet prevents strokes and heart attacks, reduces the risk of heart failure, and lowers cardiovascular complications.

Have a query?

Directions for Use

  • Bisobis A 2.5 Tablet can be taken with or without food, but taking it after meals may help reduce the risk of dizziness or stomach upset.
  • It is advised to take Bisobis A 2.5 Tablet once daily at the same time each day, preferably in the morning, or as prescribed by your doctor.
  • Swallow Bisobis A 2.5 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Bisobis A 2.5 Tablet contains Amlodipine and Bisoprolol fumarate, which help control hypertension, reducing strain on the heart and arteries.
  • By lowering blood pressure, Bisobis A 2.5 Tablet helps prevent heart-related complications such as heart attacks, strokes, and heart failure.
  • Amlodipine, a calcium channel blocker, widens and relaxes blood vessels, improving blood flow and reducing the heart’s workload.
  • Bisoprolol fumarate, a beta-blocker, decreases the heart rate and relaxes blood vessels, allowing the heart to pump more efficiently.
  • Long-term use helps prevent damage to vital organs like the kidneys, brain, and heart caused by uncontrolled hypertension.
  • By improving blood supply to the heart muscles, Bisobis A 2.5 Tablet helps reduce the frequency and severity of angina attacks.
  • The dual action of the two medicines helps maintain stable blood pressure and enhances circulatory system function.

How Bisobis A 2.5 Tablet Works

Bisobis A 2.5 Tablet contains Amlodipine and Bisoprolol fumarate. Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol fumarate helps in relaxing the blood vessels by blocking the action of certain natural substances in the body. Together, Bisobis A 2.5 Tablet helps treat high blood pressure.

Storage

• Store in a cool and dry place away from sunlight.• Keep Bisobis A 2.5 Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Bisobis A 2.5 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Bisobis A 2.5 Tablet

An overdose of Bisobis A 2.5 Tablet may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Bisobis A 2.5 Tablet if you are allergic to any of its components.
  • Inform your doctor if you have heart problems, diabetes, Prinzmetal angina, psoriasis, pheochromocytoma, very slow heartbeat, serious heart condition, heart blockage, kidney or liver problems or muscle disorder (myasthenia gravis, rhabdomyolysis).
  • Let your doctor know if you have a breathing problem (COPD, bronchitis, emphysema), low blood pressure (hypotension), depression, previous heart failure, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).
  • Consult your doctor if you are pregnant or breastfeeding.
  • Bisobis A 2.5 Tablet is not recommended in children as the safety and efficacy of Bisobis A 2.5 Tablet have not yet been established.
  • Keep your doctor informed if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineRifapentine
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Bisobis A 2.5 Tablet:
Using Bisobis A 2.5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Bisobis A 2.5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Coadministration of Bisobis A 2.5 Tablet and Rifapentine may significantly reduce the blood levels of Bisobis A 2.5 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Bisobis A 2.5 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipineCarbamazepine
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Coadministration of Bisobis A 2.5 Tablet and carbamazepine together may significantly reduce Bisobis A 2.5 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Bisobis A 2.5 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Coadministration of Bisobis A 2.5 Tablet and Idelalisib may raise Bisobis A 2.5 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Bisobis A 2.5 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineDolasetron
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Using dolasetron together with Bisobis A 2.5 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Bisobis A 2.5 Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineMitotane
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Using Bisobis A 2.5 Tablet and mitotane together may drastically lower Bisobis A 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Bisobis A 2.5 Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Co-administration of Tizanidine and Bisobis A 2.5 Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Bisobis A 2.5 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Using Bisobis A 2.5 Tablet and phenytoin together may drastically lower Bisobis A 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Bisobis A 2.5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Co-administration of Bisobis A 2.5 Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Bisobis A 2.5 Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineRifabutin
Severe
How does the drug interact with Bisobis A 2.5 Tablet:
Using Bisobis A 2.5 Tablet and rifabutin together may lower Bisobis A 2.5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Bisobis A 2.5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL FUMARATE-2.5MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL FUMARATE-2.5MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit or grapefruit juice with Bisobis A 2.5 Tablet can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.

Diet & Lifestyle Advise

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.
  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega-3 fatty acids-containing food and drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil, as they may help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Bisobis A 2.5 Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

You are recommended not to consume alcohol along with Bisobis A 2.5 Tablet as it may potentiate the blood pressure-lowering effect of Bisobis A 2.5 Tablet .

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribed only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Bisobis A 2.5 Tablet is not recommended in breastfeeding mothers.

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Driving

Caution

Bisobis A 2.5 Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Bisobis A 2.5 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Bisobis A 2.5 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Unsafe

Bisobis A 2.5 Tablet is not recommended in children as the safety and efficacy of Bisobis A 2.5 Tablet have not yet been established.

FAQs

Bisobis A 2.5 Tablet is used to treat high blood pressure, a chronic condition in which the force exerted by the blood against the artery wall is high.

Bisobis A 2.5 Tablet works by reducing the workload on the heart and relaxing the blood vessels to ensure a fluid flow of blood. Thereby, lowering high blood pressure.

Do not stop taking Bisobis A 2.5 Tablet without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Bisobis A 2.5 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Bisobis A 2.5 Tablet .

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidneys and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Bisobis A 2.5 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Bisobis A 2.5 Tablet may cause palpitations, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.

Try not to miss a dose in the first place. If you missed a dose of Bisobis A 2.5 Tablet , you are advised to take it as soon as you remember. However, if it is time for the scheduled dose, skip the missed dose and take the scheduled dose. Avoid taking a double dose of Bisobis A 2.5 Tablet as it may lead to low blood pressure.

No, Bisobis A 2.5 Tablet is not habit-forming. However, it is essential to use this medication under medical supervision and follow the prescribed dosage and duration.

Uncontrolled hypertension gradually destroys the arteries, causing them to harden. As the arteries constrict and become less flexible, the heart works harder to circulate blood. Uncontrolled high blood pressure can cause a stroke, heart attack, heart failure, and other heart problems, damage to the kidneys, memory, and eyesight, and contribute to erectile dysfunction.

Taking Bisobis A 2.5 Tablet may cause dizziness in some individuals. This medication can temporarily drop blood pressure, resulting in lightheadedness or dizziness, especially when standing up quickly or changing positions. The vasodilation effect of amlodipine and the heart rate slowing effect of bisoprolol can both contribute to this side effect. If you experience dizziness after taking this medication, it's essential to move slowly when standing up, avoid sudden changes in position, and sit or lie down if the dizziness occurs. If the dizziness persists or worsens, consult your doctor, as they may need to adjust your dosage or recommend alternative treatments. Remember to prioritize your safety and consult your healthcare provider if you have any concerns.

Store Bisobis A 2.5 Tablet at room temperature, away from heat and direct sunlight. When it's no longer needed or has expired, dispose of it responsibly. Check your local waste management guidelines for instructions. Make sure it is not consumed by children, pets, and other people.

The use of Bisobis A 2.5 Tablet is contraindicated to certain individuals. Those with a known hypersensitivity to amlodipine, bisoprolol, or any component of Bisobis A 2.5 Tablet should avoid using it. Additionally, it may not recommended for patients with cardiogenic shock, heart block (second or third-degree), sick sinus syndrome, or bradycardia (heart rate < 60 beats per minute) and pulmonary oedema (a condition characterized by fluid accumulation in the lungs). Furthermore, pregnant and breastfeeding women should not use this medication, as it may harm the fetus or baby. Finally, concurrent use with certain medications, such as beta-blockers, calcium channel blockers, digoxin, and catecholamine-depleting drugs, is also contraindicated. It's essential to consult a healthcare professional to discuss individual circumstances and determine if Bisobis A 2.5 Tablet is safe to use.

The use of Bisobis A 2.5 Tablet can lead to headaches in some individuals, typically due to the vasodilation effects of amlodipine, which can cause blood vessels to widen, or the beta-blocking effects of bisoprolol. While headaches are a common side effect in around 10-20% of patients, they are usually mild and temporary. If you experience a headache while taking this medication, In that case, it's essential to consult your healthcare provider to determine the best course of action, as they can recommend strategies to manage headaches or adjust your dosage if necessary and also rule out any underlying conditions or interactions with other medications.

Common side effects of Bisobis A 2.5 Tablet may include headache, dizziness, palpitations, abdominal pain, oedema, ankle swelling, fatigue, cold extremities, nausea, vomiting, diarrhoea, and constipation. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

Use caution when driving or operating heavy machinery, as Bisobis A 2.5 Tablet may cause drowsiness or impaired coordination.

Limit alcohol intake or avoid it, as it may potentiate the blood pressure-lowering effects of Bisobis A 2.5 Tablet .

Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

Corona House, Block C, Mondeal Business Park, Near Gurudwara,, S. G. Highway, Thaltej, Thaltej, Ahmedabad, Gujarat 380059
Other Info - BIS0212

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 15, 2025 | 12:15 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.6126.pdf
  2. https://patient.info/medicine/bisoprolol-a-beta-blocker-cardicor-congescor
  3. https://www.drugs.com/drug-interactions/amlodipine-index.html?filter=3
  4. https://www.drugs.com/drug-interactions/bisoprolol.html
  5. https://www.medicines.org.uk/emc/files/pil.2743.pdf
  6. https://www.nhs.uk/medicines/amlodipine/

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