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Bortenat 2 mg Injection

Bortenat 2 mg Injection

Prescription drug
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Composition

BORTEZOMIB-2MG

Manufacturer/Marketer

Natco Pharma Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

About Bortenat 2 mg Injection

Bortenat 2 mg Injection belongs to a group of anti-cancer medicines used to treat adult patients with multiple myeloma and mantle cell lymphoma who have received at least one prior therapy. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer it affects several areas of the body, such as the spine, skull, pelvis, and ribs. Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma (NHL). It develops when B-cells (also called B-lymphocytes) become abnormal. B-cells are white blood cells that fight infection.

Bortenat 2 mg Injection contains 'Bortezomibx' that works by interfering with how proteasomes work, which may cause cancer cells to die and may stop cancer from growing and eventually kills them.

Bortenat 2 mg Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection into your vein (intravenously or IV) or under your skin (subcutaneously or SC). Bortenat 2 mg Injection must not be administered into your spinal fluid (intrathecally). You may experience nausea, diarrhoea, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), peripheral neuropathy (nerves malfunction), fatigue, neuralgia, anaemia, leukopenia, constipation, vomiting, lymphopenia, rash, pyrexia, and anorexia. Most of these side effects of Bortenat 2 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Bortenat 2 mg Injection for as long as your doctor has prescribed. Do not stop the Bortenat 2 mg Injection midway. Talk to your doctor before taking Bortenat 2 mg Injection if you have allergies or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Avoid taking Bortenat 2 mg Injection if you are pregnant or breastfeeding because this Bortenat 2 mg Injection can cause harmful effects on the unborn baby. Both women and men using this Bortenat 2 mg Injection should use birth control to avoid pregnancy.

Uses of Bortenat 2 mg Injection

Treatment of Multiple myeloma and Mantle cell lymphoma.

Medicinal Benefits

Bortenat 2 mg Injection contains the active substance bortezomib, also-called ‘proteasome inhibitor. Proteasomes play an important role in controlling cell function and growth. By interfering with their function, thereby it can kill cancer cells. Bortenat 2 mg Injection is used to treat multiple myeloma (a cancer of the bone marrow) and mantle cell lymphoma (a type of cancer affecting the lymph nodes) in 18 years or older patients. It can be used alone or together with other medicines.

Directions for Use

Bortenat 2 mg Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bortenat 2 mg Injection

  • Nausea
  • Diarrhoea
  • Thrombocytopenia (low blood platelet count)
  • Neutropenia (too few neutrophils)
  • Peripheral neuropathy (nerves malfunction)
  • Fatigue (overtired)
  • Neuralgia (pain in the head or face)
  • Muscle pain, bone pain
  • Anaemia (low red blood cell Count)
  • Leukopenia (Low White Blood Cell Count)
  • High blood pressure
  • Constipation
  • Dehydration
  • Vomiting
  • Loss of appetite
  • Lymphopenia (Low lymphocytes Count)
  • Rash
  • Pyrexia (raised body temperature)
  • Anorexia (lack or loss of appetite for food)
  • Infections, including pneumonia, respiratory infections, bronchitis, fungal infections, coughing with phlegm, flu-like illness

Drug Warnings

To treat your condition effectually, continue taking Bortenat 2 mg Injection for as long as your doctor has prescribed. Do not stop the Bortenat 2 mg Injection midway. Talk to your doctor before taking Bortenat 2 mg Injection if you have allergies or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. And also, inform your doctor if you have diabetes because this medicine can affect your blood glucose levels. Your doctor may require close monitoring of your blood glucose levels and change your diabetes medicine dose while being treated with Bortenat 2 mg Injection. Avoid taking Bortenat 2 mg Injection if you are pregnant because this Bortenat 2 mg Injection can cause harmful effects on the unborn baby. Both women and men using this Bortenat 2 mg Injection should use birth control to avoid pregnancy and for at least six months following treatment. Do not breastfeed during treatment with Bortenat 2 mg Injection and four months after your final dose of Bortenat 2 mg Injection.

Drug Interactions

Drug-Drug Interactions: Bortenat 2 mg Injection interacts with antifungal medication (ketoconazole), HIV medication (ritonavir), antibiotic medication (rifampicin), epilepsy medications (carbamazepine, phenytoin or phenobarbital), depression medication (St. John’s Wort), and oral antidiabetics.

Drug-Food Interactions: No food interaction was found.

Drug-Disease Interactions: Inform your doctor before taking Bortenat 2 mg Injection; it requires close monitoring if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), and hepatic disorders.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • RITONAVIR
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep, and rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugars.

Special Advise

  • Bortenat 2 mg Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Bortenat 2 mg Injection.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Bortenat 2 mg Injection may make your skin sensitive to sunlight.

Disease/Condition Glossary

Multiple myeloma, also known as myeloma, is a type of bone marrow cancer it affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma (NHL). It develops when B-cells (also called B-lymphocytes) become abnormal. B-cells are white blood cells that fight infection.

Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Bortenat 2 mg Injection. It could lead to avoiding unpleasant side effects.

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Pregnancy

Unsafe

Bortenat 2 mg Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Bortenat 2 mg Injection and at least six months afterwards. Please discuss with your doctor any concerns regarding this.

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Breast Feeding

Unsafe

Bortenat 2 mg Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Caution

Bortenat 2 mg Injection may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Bortenat 2 mg Injection may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

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Liver

Caution

If you have a history or evidence of liver-related diseases, inform the doctor before prescribing the Bortenat 2 mg Injection. Your doctor will weigh the benefits and potential risks before prescribing them.

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Kidney

Caution

If you have a history or evidence of kidney-related diseases, inform the doctor before prescribing the Bortenat 2 mg Injection. Your doctor will weigh the benefits and potential risks before prescribing them.

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Children

Unsafe

Bortenat 2 mg Injection should not be used by children below 18 years of age, as efficacy and safety have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info -

FAQs

Bortenat 2 mg Injection contains the active substance bortezomib, also-called ‘proteasome inhibitor. Proteasomes play an important role in controlling cell function and growth. By interfering with their function, thereby it can kill cancer cells.
Bortenat 2 mg Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection into your vein (intravenously or IV) or under your skin (subcutaneously, or SC). Bortenat 2 mg Injection must not be administered into your spinal fluid (intrathecally).
Yes, Bortenat 2 mg Injection can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
Avoid taking Bortenat 2 mg Injection if you are pregnant because Bortenat 2 mg Injection can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Bortenat 2 mg Injection.
Before you receive treatment with Bortenat 2 mg Injection, tell your doctor about all of your medical conditions. You should not receive Bortenat 2 mg Injection if you are allergic to bortezomib or any contents in Bortenat 2 mg Injection.
If not given an inappropriate dose, Bortenat 2 mg Injection can cause toxic effects, although not everyone gets it. So, Bortenat 2 mg Injection is prescribed by a doctor experienced in using medications to treat cancer only.

Author Details

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