Bosentas 62.5 Tablet 10's

(Inclusive of all Taxes)

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Written By Veda Maddala , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

Bosentas 62.5 Tablet is used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It can even increase our exercising ability, delay disease progression, and improve quality of life. It contains Bosentan, which narrows the blood vessels and increases the pressure in the blood vessels of the lungs. It helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs. In some cases, you may experience swelling of legs and ankles, headaches, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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About Bosentas 62.5 Tablet

Bosentas 62.5 Tablet is an anti-hypertension medication primarily used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). Bosentas 62.5 Tablet can even increase our exercising ability, delay disease progression, and improve quality of life. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart.

Bosentas 62.5 Tablet contains Bosentan, an endothelin receptor antagonist used to treat pulmonary arterial hypertension. It works by blocking the action of endothelin. Endothelin narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs.

Take Bosentas 62.5 Tablet as prescribed by your doctor. You are advised to take Bosentas 62.5 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience swelling of legs and ankles, headaches, and diarrhoea in some cases. Most of these side effects of Bosentas 62.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Please inform your doctor if you have liver dysfunction before starting Bosentas 62.5 Tablet . If you are pregnant or breastfeeding, do not take Bosentas 62.5 Tablet a pregnancy category X drug. If you are taking Bosentas 62.5 Tablet , women should use a reliable form of the contraceptive pill to avoid pregnancy and continue to use it one month after stopping Bosentas 62.5 Tablet . Also, the blood test for liver functions should be monitored regularly and for the haemoglobin level.

Uses of Bosentas 62.5 Tablet

Bosentas 62.5 Tablet is used in the treatment of high blood pressure in the lungs and related conditions. The detailed uses of Bosentas 62.5 Tablet are as follows: • Treatment of pulmonary arterial hypertension (PAH): Bosentas 62.5 Tablet helps lower high blood pressure in the arteries of the lungs, improving exercise ability and slowing disease progression. • Management of idiopathic PAH: Used in patients with an unknown cause of PAH to relieve symptoms such as shortness of breath and fatigue. • PAH associated with connective tissue disease: Bosentas 62.5 Tablet lowers symptoms and improves quality of life in patients with PAH associated with connective tissue medical conditions, such as scleroderma. • Prevention of digital ulcers: Reduces the occurrence of painful finger or toe ulcers in patients with systemic sclerosis.

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Directions for Use

Bosentas 62.5 Tablet can be taken with or without food as advised by the doctor.
Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
Swallow Bosentas 62.5 Tablet as a whole with a glass of water.
Do not crush, break or chew it.

Medicinal Benefits

Bosentas 62.5 Tablet is an anti-hypertension medication primarily used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). Bosentas 62.5 Tablet can even increase our exercising ability, delay disease progression, and improve quality of life. It works by blocking the action of endothelin. Endothelin narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs. It also improves the quality of life, exercise ability, and delays the progression of pulmonary arterial hypertension.

How Bosentas 62.5 Tablet Works

Bosentas 62.5 Tablet contains Bosentan, an endothelin receptor antagonist used to treat pulmonary arterial hypertension. It works by blocking the action of endothelin. Endothelin narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Bosentas 62.5 Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Abnormal liver function test

Water Retention

Avoid diet rich in salt and carbohydrates
Drink plenty of water and stay hydrated.
Exercise regularly and maintain a healthy lifestyle.
Take potassium rich foods like potatoes, spinach, tomatoes, sea food and dairy products.
Take beverages containing caffeine like coffee and tea.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Unusual Tiredness Or Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Increased Alanine Aminotransferase (ALT)

To improve liver health and aid in the removal of toxins, drink lots of water.
Alcohol consumption should be reduced or stopped because it can raise ALT levels and impair liver function.
Consume a well-rounded diet full of whole grains, fruits, and vegetables. Limit items that strain the liver, such as processed, fatty, or fried foods.
You can monitor your ALT levels and make treatment modifications with the support of routine blood tests.

Increased Aspartate Aminotransferase (AST)

Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
Reduced alcohol intake can enhance liver enzyme function.
Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
Liver function tests regularly can help manage increased levels of AST.

What if I have taken an overdose of Bosentas 62.5 Tablet

Do not take more than the prescribed dose of Bosentas 62.5 Tablet as it may cause an overdose. The symptoms of overdose include nausea, vomiting, headache, sweating, fast heartbeat, dizziness, or blurred vision. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Bosentas 62.5 Tablet if you are allergic to Bosentas 62.5 Tablet or any of its ingredients. Please inform your doctor if you have liver dysfunction before starting Bosentas 62.5 Tablet . If you are pregnant or breastfeeding, do not take Bosentas 62.5 Tablet as it is a pregnancy category X drug. It can lead to defects in the baby if taken during pregnancy. Also, after stopping Bosentas 62.5 Tablet at least after a gap of one month, you should try to conceive so that Bosentas 62.5 Tablet flushes out of the body completely. If you are taking Bosentas 62.5 Tablet , women should use a reliable form of the contraceptive pill to avoid pregnancy and continue to use it one month after stopping Bosentas 62.5 Tablet . Blood tests for liver function should be monitored regularly, and for haemoglobin level as well. Low haemoglobin could be a sign of anaemia.

Drug-Drug Interactions

BosentanCiclosporin

Critical

BosentanRegorafenib

Critical

Drug-Drug Interactions

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BosentanCiclosporin

Critical

How does the drug interact with Bosentas 62.5 Tablet:
When Bosentas 62.5 Tablet is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Ciclosporin with Bosentas 62.5 Tablet is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

BosentanRegorafenib

Critical

How does the drug interact with Bosentas 62.5 Tablet:
Taking regorafenib with Bosentas 62.5 Tablet it can increases the risk of side effects.

How to manage the interaction:
Taking Regorafenib with Bosentas 62.5 Tablet is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

BosentanGuanfacine

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Coadministration of guanfacine and Bosentas 62.5 Tablet may significantly reduce the blood levels of guanfacine, which may make the medication less effective in treating your condition.

How to manage the interaction:
Co-administration of Bosentas 62.5 Tablet with Guanfacine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

BosentanRanolazine

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Taking ranolazine and Bosentas 62.5 Tablet together may significantly reduce the blood levels of ranolazine, making the medication less effective.

How to manage the interaction:
Although using Bosentas 62.5 Tablet and Ranolazine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.

BosentanNorethisterone

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Co-administration of Norethisterone with Bosentas 62.5 Tablet can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Norethisterone with Bosentas 62.5 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.

BosentanDienogest

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Co-administration of Dienogest with Bosentas 62.5 Tablet may decrease the effectiveness of Dienogest.

How to manage the interaction:
Although there is a possible interaction, Dienogest can be taken with Bosentas 62.5 Tablet if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

BosentanTizanidine

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Coadministration of tizanidine and Bosentas 62.5 Tablet can increase the risk of low blood pressure.

How to manage the interaction:
Although using Tizanidine and Bosentas 62.5 Tablet together can result in an interaction, they can be taken together if prescribed by your doctor. Consult your doctor if you experience dizziness, headaches, palpitations, or excessive sweating. Do not stop taking any medications without consulting a doctor.

BosentanEtonogestrel

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Taking etonogestrel with Bosentas 62.5 Tablet may reduce the blood levels and effects of etonogestrel, which may make it less effective.

How to manage the interaction:
Co-administration of Etonogestrel with Bosentas 62.5 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

BosentanCariprazine

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Taking Cariprazine with Bosentas 62.5 Tablet may reduce the blood levels of cariprazine, which may make the medication less effective.

How to manage the interaction:
Taking Bosentas 62.5 Tablet with Cariprazine together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.

BosentanBosutinib

Severe

How does the drug interact with Bosentas 62.5 Tablet:
Taking bosutinib with Bosentas 62.5 Tablet ay reduce the blood levels of bedaquiline, which may decrease its effectiveness in treating your condition.

How to manage the interaction:
There may be a possibility of interaction between Bosutinib and Bosentas 62.5 Tablet, but it can be taken if prescribed by a doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Keep your weight under control with a BMI of 19.5-24.9.
Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mmHg.
Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
If you are taking alcohol, then only one serving for women and two servings for men is advisable.
Quitting smoking is the best strategy to lower the risk of heart disease.
Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
Monitor your blood pressure daily, and if there is too much fluctuation, then immediately contact your doctor.
Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Alcohol

Unsafe

Bosentas 62.5 Tablet should not be taken along with alcohol to avoid unpleasant side effects.

Pregnancy

Unsafe

Bosentas 62.5 Tablet is a category X pregnancy drug and it can cause harm to the baby, so it should not be taken if you are pregnant or planning to get pregnant.

Breast Feeding

Unsafe

Bosentas 62.5 Tablet is known to pass through breast milk and may cause harm to the baby, so it should not be taken if you are breastfeeding.

Driving

Caution

Bosentas 62.5 Tablet may cause hypotension (low blood pressure), which may make you feel dizzy. If you feel dizzy, please do not drive a car.

Liver

Caution

Bosentas 62.5 Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

Kidney

Caution

Bosentas 62.5 Tablet to be taken with caution, especially if you have or have had a kidney disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

Children

Caution

Bosentas 62.5 Tablet is not recommended for use in children.

FAQs

What is the use of Bosentas 62.5 Tablet ?

Bosentas 62.5 Tablet is used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). Bosentas 62.5 Tablet can even increase our exercising ability, delay disease progression, and improve quality of life.

How does Bosentas 62.5 Tablet work?

Bosentas 62.5 Tablet is an anti-hypertension medication primarily used to treat‚ pulmonary arterial hypertension. It works by blocking the action of endothelin. Endothelin‚ narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bosentas 62.5 Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs.

What is pulmonary arterial hypertension?

Pulmonary arterial hypertension is high pressure in the blood vessels that carry blood from the heart to the lungs. It can be due to constriction of blood vessels or some blockage in blood vessels pathway.

Can Bosentas 62.5 Tablet cause anemia?

Yes, in rare cases, $Name can cause anaemia. It can decrease your haemoglobin level, which may lead to anaemia. So, please regularly check your haemoglobin level if you are taking Bosentas 62.5 Tablet .

How to take Bosentas 62.5 Tablet ?

It is usually taken with or without food. It should be swallowed as a whole with a glass of water; do not chew or crush it. Take it exactly as directed. Do not take more or less of it or more often than your doctor prescribes.

Can I take Bosentas 62.5 Tablet if I have liver problems?

If you have liver problems, use Bosentas 62.5 Tablet with caution and only under the guidance of your doctor. Patients with a history of liver disease should be closely monitored while taking Bosentas 62.5 Tablet , as it may affect liver function. Your doctor may adjust the dosage or frequency of Bosentas 62.5 Tablet based on your individual needs and medical condition.

Is Bosentas 62.5 Tablet safe in pregnancy?

Bosentas 62.5 Tablet is a category X pregnancy drug, and it can cause harm to the baby, so it should not be taken if you are pregnant or planning to get pregnant.

What are the side effects of Bosentas 62.5 Tablet ?

Common side effects of Bosentas 62.5 Tablet may include swelling of legs and ankles, headaches, and diarrhoea in some cases. Most of these side effects of Bosentas 62.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.