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compositionComposition:BOSUTINIB-400MG
prescription
Prescription Medicine
info
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Bosuvi 400 mg Tablet is used to treat certain cancers such as Philadelphia chromosome-positive chronic myeloid leukaemia. It contains Bosutinib, which belongs to the class of kinase inhibitors. It works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduces the spread of cancer to other parts of the body.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BOSUTINIB-400MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bosuvi 400 mg Tablet

Bosuvi 400 mg Tablet is a prescription medication used to treat adults with a specific type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It is prescribed both for newly diagnosed patients and for those who have not responded to or could not tolerate previous therapies.

For this medication to work effectively, you must take it consistently at the same time every day. You should always take your dose with food, as this significantly increases how well your body absorbs the medicine. Incorporating simple dietary adjustments, like eating bland foods and drinking plenty of fluids, can help support your body during treatment.

While taking Bosuvi 400 mg Tablet , you may experience common side effects like stomach discomfort and mild skin rashes. However, it is vital to contact your healthcare team immediately if you notice serious signs such as severe diarrhoea, yellowing of your eyes or skin, or sudden swelling in your legs.

Do not take this if you have a known severe allergy to any of its ingredients. Before starting treatment, you must discuss your medical history with your doctor, especially if you have pre-existing liver damage, kidney disease, or cardiac complications.

This medicine interacts with several other substances, including certain over-the-counter stomach acid reducers, which can prevent the drug from working properly. If you are pregnant, planning to become pregnant, or breastfeeding, you should talk to your doctor immediately, as this medication can harm an unborn baby.

Uses of Bosuvi 400 mg Tablet

This medication is specifically approved for the treatment of blood and bone marrow cancers. Your doctor may prescribe Bosuvi 400 mg Tablet for the following indications:

  • Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) is a type of blood cancer caused by an abnormal gene change (called the Philadelphia chromosome) that makes certain white blood cells grow and multiply out of control. Bosuvi 400 mg Tablet is used to treat this condition.
  • Resistant or intolerant Ph+ Chronic Myeloid Leukemia (CML): It is used to treat chronic, accelerated, or blast phase CML in adults who can no longer take other leukemia treatments due to severe side effects or because the previous medication stopped working.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Supports Healthy Blood Cells: The primary benefit of Bosuvi 400 mg Tablet is its ability to target and control leukemia cells, which helps manage the disease and prevent it from progressing to more severe stages. By keeping the growth of abnormal blood cells in check, this treatment helps restore a healthier balance of red blood cells, white blood cells, and platelets in your body.
  • Supports Better Quality of Life: For many patients, successfully controlling the leukemia leads to a noticeable reduction in disease-related symptoms, such as severe fatigue, unexplained weight loss, and bone pain. This physical relief allows patients to maintain better energy levels and continue their daily routines with greater comfort.
Side effects of Bosuvi 400 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Bosuvi 400 mg Tablet should be taken with meals.
  • Recommended to take once daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow Bosuvi 400 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Bosuvi 400 mg Tablet Works

In people with Philadelphia chromosome-positive (Ph+) CML, an abnormal gene creates a protein called BCR-ABL tyrosine kinase. This protein acts like a constant 'growth switch,' telling abnormal white blood cells to keep growing and multiplying when they should not.  This medicine contains Bosuvi 400 mg Tablet , works by directly binding to and blocking this abnormal BCR-ABL protein. By turning off this growth signal, the medication stops the cancer cells from dividing and multiplying, which helps reduce the number of leukemia cells in the bone marrow and bloodstream.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Bosuvi 400 mg Tablet to prevent serious adverse effects.

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Pregnancy

Unsafe

Bosuvi 400 mg Tablet is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Bosuvi 400 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data is available on the effect of Bosuvi 400 mg Tablet on breastfeeding. Bosuvi 400 mg Tablet should be avoided during breastfeeding. Hence, inform your doctor if you are breastfeeding. Your doctor may prescribe an alternative based on the symptoms and health condition.

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Driving

Unsafe

Bosuvi 400 mg Tablet may cause dizziness and may make you feel drowsy. Hence, avoid driving or operating machines after taking Bosuvi 400 mg Tablet or until you become alert.

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Liver

Caution

Bosuvi 400 mg Tablet is known to cause hepatotoxicity. Hence, inform your doctor if you have a pre-existing or a history of liver disease. A dose adjustment may be needed based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Bosuvi 400 mg Tablet . Your doctor may reduce the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Bosuvi 400 mg Tablet is not recommended for use in children below 18 years of age as the safety and efficacy are not established.

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Heart

Caution

Bosuvi 400 mg Tablet should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Bosuvi 400 mg Tablet .

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Geriatrics

Consult your doctor

Please consult a doctor before administering Bosuvi 400 mg Tablet to geriatric patients. Your doctor will prescribe Bosuvi 400 mg Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Bosuvi 400 mg Tablet

If you accidentally take more than your prescribed dose, seek emergency medical care. Keep the medication packaging with you so the healthcare providers know exactly what you have taken.

Diet & Lifestyle Advise

  • Avoid grapefruit products: Do not eat grapefruit or drink grapefruit juice while taking this medication, as it can dangerously increase the levels of the drug in your blood.
  • Stay hydrated: Drink plenty of water throughout the day, especially if you experience diarrhoea, to prevent dehydration and support kidney function.
  • Eat small, frequent meals: If you struggle with nausea or loss of appetite, eating smaller, bland portions throughout the day may be easier to tolerate than three large meals.
  • Prioritise food safety: Because your immune system may be weakened, wash all fruits and vegetables thoroughly, and avoid eating raw or undercooked meats, seafood, or eggs.
  • Protect your skin: Use a gentle, unscented moisturiser to manage dry skin, and wear sunscreen when outdoors, as your skin may be more sensitive during treatment.
health query

Have a query?

How Soon It Starts Working

The time required for Bosuvi 400 mg Tablet to start to work: The time required for Bosuvi 400 mg Tablet to show its action is not clinically established. The time for which the effects of Bosuvi 400 mg Tablet last: The duration of action for Bosuvi 400 mg Tablet is not clinically established.

What if you forget to take Bosuvi 400 mg Tablet

If you miss a dose, take it as soon as you remember, provided it is within 12 hours of your scheduled time. If more than 12 hours have passed since your missed dose, skip it entirely and take your next dose at your regular scheduled time. Do not take two doses at once to make up for a missed one.

Storage

• Store Bosuvi 400 mg Tablet tablets at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check Tablet Before Use: Inspect each tablet before taking it; do not use any tablet that is broken, chipped, or cracked.
  • Safe Tablet Handling: Caregivers should wear disposable gloves if they must handle these tablets, and pregnant individuals should avoid handling them entirely.
  • Avoid Acid-Reducing Medicines: Avoid taking antacids, H2 blockers, or proton pump inhibitors (PPIs) close to your dose, as they lower stomach acid and reduce how well the medicine is absorbed.
  • Use Effective Birth Control: Use highly effective birth control during treatment and for at least 2 weeks after your very last dose to prevent pregnancy.
  • Attend Regular Blood Tests: Keep all appointments for your scheduled blood tests, as your doctor must regularly check your liver function and blood cell counts.
  • Avoid Driving if Dizzy: Do not drive or operate heavy machinery if you feel dizzy, lightheaded, or severely fatigued.

Drug-Drug Interactions

verifiedApollotooltip
  • Avoid Acid-Reducing Medicines: Some medicines can affect how your liver breaks down Bosuvi 400 mg Tablet , changing the amount of medicine in your body. For example, certain antifungal medicines (such as ketoconazole), some antibiotics (such as clarithromycin), and other medicines that slow down this process can increase Bosuvi 400 mg Tablet levels and raise the risk of side effects. On the other hand, medicines such as rifampin or the herbal supplement St. John's wort can make your body break down Bosuvi 400 mg Tablet faster, making it less effective. Always tell your doctor or pharmacist about all prescription medicines, over-the-counter medicines, vitamins, and herbal supplements you take.
BosutinibYellow fever vaccine
Critical
BosutinibTofacitinib
Severe

Drug-Drug Interactions

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BosutinibYellow fever vaccine
Critical
How does the drug interact with Bosuvi 400 mg Tablet:
Combining Yellow fever vaccine with Bosuvi 400 mg Tablet can increase the risk of infection.

How to manage the interaction:
Taking Yellow fever vaccine with Bosuvi 400 mg Tablet can result in an interaction, but it can be taken if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
BosutinibTofacitinib
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Using tofacitinib together with Bosuvi 400 mg Tablet may increase the risk of infections.

How to manage the interaction:
Although there is an interaction between Tofacitinib and Bosuvi 400 mg Tablet, it can be taken if prescribed by a doctor. However, consult a doctor if you experience diarrhea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop using any medications without a doctor's advice.
BosutinibFosamprenavir
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking Bosuvi 400 mg Tablet with fosamprenavir can increase the blood levels of Bosuvi 400 mg Tablet. This can increase side effects such as nausea, vomiting, abdominal pain, and diarrhea.

How to manage the interaction:
Although there is an interaction between Bosuvi 400 mg Tablet and fosamprenavir, it can be taken if prescribed by a doctor. Contact your doctor if you experience fatigue, dizziness, fainting, diarrhea, sore throat, muscle aches, red or irritated skin, discomfort when urinating. Do not discontinue any medications without consulting a doctor.
BosutinibEfavirenz
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking Bosuvi 400 mg Tablet with efavirenz can decreases the blood levels and effects of Bosuvi 400 mg Tablet.

How to manage the interaction:
Although there is an interaction between Bosuvi 400 mg Tablet and Efavirenz, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
BosutinibVerapamil
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking verapamil with Bosuvi 400 mg Tablet may significantly increase the blood levels of Bosuvi 400 mg Tablet.

How to manage the interaction:
Although taking Bosuvi 400 mg Tablet together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, diarrhea, sore throat, muscle aches, red or inflamed skin, burning during urination. Do not stop taking any medication without consulting a doctor.
BosutinibPasireotide
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking Bosuvi 400 mg Tablet and Pasireotide together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Bosuvi 400 mg Tablet and Pasireotide together can cause an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or fainting. Do not discontinue any medications without consulting a doctor.
BosutinibZiprasidone
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking Bosuvi 400 mg Tablet and Ziprasidone together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Bosuvi 400 mg Tablet and Ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or fainting. Do not discontinue any medications without consulting a doctor.
BosutinibTelaprevir
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking Bosuvi 400 mg Tablet with telaprevir can considerably increase blood levels of Bosuvi 400 mg Tablet, which can lead to an increased risk of side effects.

How to manage the interaction:
Although there is an interaction between Bosuvi 400 mg Tablet and telaprevir, they can be taken together if prescribed by a doctor. However, if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
BosutinibGlycerol
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking Glycerol with Bosuvi 400 mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Glycerol with Bosuvi 400 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
BosutinibPanobinostat
Severe
How does the drug interact with Bosuvi 400 mg Tablet:
Taking Bosuvi 400 mg Tablet and Panobinostat can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Bosuvi 400 mg Tablet and panobinostat, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or fainting. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Avoid Grapefruit Products: Do not consume grapefruit, grapefruit juice, or Seville oranges during your treatment. These food products block the enzymes that break down the medication, which can lead to a dangerous buildup of the drug in your body. Always take this medication with food, as taking it on an empty stomach reduces its effectiveness.
BOSUTINIB-400MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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BOSUTINIB-400MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit or grapefruit juice with Bosuvi 400 mg Tablet can increase the blood levels and effects of Bosuvi 400 mg Tablet, which may increase the risk of side effects. Avoid the consumption of grapefruit and grapefruit juice.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Bosuvi 400 mg Tablet is used to treat Philadelphia chromosome-positive chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.
Bosuvi 400 mg Tablet contains Bosutinib, which works by inhibiting the action of abnormal proteins that cause the multiplication of cancerous cells.
Bosuvi 400 mg Tablet is known to cause embryo-fetal toxicity; hence, it is contraindicated for use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least six months after completion of the treatment.
You should call your doctor right away if you experience any of the following symptoms such as severe dizziness or fainting, difficulty breathing or shortness of breath, persistent nausea or vomiting, severe stomach pain or cramps, unusual bleeding or bruising, severe skin rash or itching and signs of an allergic reaction (such as swelling of the face, lips, or tongue).
Regular scans will determine whether your tumour is responding to the treatment. Your doctor will decide when those scans should be done. Until your doctor advises you to stop taking Bosuvi 400 mg Tablet , continue taking it.
Bosuvi 400 mg Tablet increases the risk of bleeding or infection since it reduces the number of platelets and white blood cells in your blood. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get fever, chills, cough.
Yes, Bosuvi 400 mg Tablet can affect your lungs. One of the potential side effects is pulmonary toxicity, which can lead to symptoms such as severe shortness of breath, dry cough, dizziness, and extreme tiredness. If you experience any of these symptoms, please consult your doctor immediately.
Bosuvi 400 mg Tablet does not cause hair loss. However, if you notice hair loss while taking Bosuvi 400 mg Tablet , please consult your doctor.
Avoid sitting or standing in one position for too long. Change your posture frequently to relieve pressure on nerves Regular exercise can improve circulation and reduce the risk of nerve compression and ensure your diet includes essential vitamins and minerals, especially B vitamins, which are crucial for nerve health. However, consult your doctor for proper guidance.
Changes in your skin such as rashes, dryness, or itching can be a side effect of Bosuvi 400 mg Tablet . Use a gentle, fragrance-free moisturizer to keep your skin hydrated. Stay away from harsh soaps, detergents, and other potential skin irritants. If the skin changes are severe or persistent, please consult your doctor.
To relieve constipation during treatment with Bosuvi 400 mg Tablet , you can include more fibre-rich foods in your diet, such as fruits, vegetables, whole grains, and legumes. Drink plenty of water. Engage in regular physical activity to help stimulate bowel movements. However, if it persists, please consult your doctor.
Yes, nausea and extreme tiredness are known side effects of Bosuvi 400 mg Tablet . Take some rest and avoid certain foods such as salty, spicy, fried, or fatty foods that can aggravate nausea and stay hydrated by drinking plenty of water. Eat and drink often in small amounts. These side effects can occur as your body adjusts to Bosuvi 400 mg Tablet . However, if they become severe or persistent, please consult your doctor.
Changes in taste, such as a metallic taste or loss of taste, are common side effects of Bosuvi 400 mg Tablet . To overcome this side effect, rinse your mouth with a solution of salt and bicarbonate of soda before meals to neutralize bad tastes, use extra seasonings, herbs, and spices to enhance the flavour of your food. Stay hydrated by drinking plenty of water to help cleanse your palate. However, if this side effect persists please consult your doctor.
The common side effects of Bosuvi 400 mg Tablet are rash, fatigue, headache, back pain, decreased platelet count, back pain, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, and dizziness. If any of these side effects persist or worsen, please consult your doctor.
No. You must always take this medication with food. Taking it with a meal helps your body absorb the drug properly so that it can work effectively against the leukemia cells. If you have trouble eating, talk to your doctor or pharmacist.
Diarrhoea is a common side effect, but severe diarrhoea can lead to dangerous dehydration. Contact your doctor immediately if you experience persistent or watery diarrhea. They may prescribe an antidiarrheal medicine or adjust your treatment. Talk to your doctor before taking any over-the-counter anti-diarrheal remedies.
You should avoid proton pump inhibitors (like omeprazole) completely. For short-term relief, you may use local antacids, but you must space them out by taking them at least 2 hours before or 2 hours after your dose. Talk to your doctor or pharmacist for a safe acid-reduction plan.
You will need frequent blood tests, especially during the first few months of treatment. These tests allow your doctor to monitor your liver health, kidney function, and blood cell counts. Your doctor will tell you exactly how often you need to have your blood drawn.
It is best to avoid or strictly limit alcohol during your treatment. Both alcohol and this medication are processed by the liver, and combining them can increase your risk of developing liver damage. Talk to your doctor about what is safe for you.
Do not take a broken or chipped tablet. Because this is a specialised medication, direct contact with the active powder should be avoided. Wash your hands thoroughly with soap and water if you accidentally touch a damaged tablet, and contact your pharmacist for disposal instructions.
Treatment is typically long-term, continuing as long as the medication successfully controls your leukemia and you do not experience intolerable side effects. Your oncologist will regularly review your progress and decide how long you should continue. Talk to your doctor for personalised guidance.

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Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - BOS0080
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