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compositionComposition:BOSENTAN-125MG
prescription
Prescription Medicine
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Bozetan 125mg Tablet is used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It can even increase our exercise ability, delay disease progression, and improve quality of life. It contains Bosentan, which narrows the blood vessels and increases pressure in the lungs. It helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs. In some cases, you may experience swelling of legs and ankles, headaches, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

BOSENTAN-125MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Bozetan 125mg Tablet

Bozetan 125mg Tablet is an oral prescription medicine used to treat pulmonary arterial hypertension, which is high blood pressure in the blood vessels that supply the lungs. It works by targeting specific proteins that cause these blood vessels to narrow, thereby improving blood flow and reducing the workload on your heart. This medicine is prescribed to help improve your physical exercise capacity and slow down the clinical worsening of your symptoms.

To get the most benefit, you must take Bozetan 125mg Tablet consistently every day, exactly as prescribed by your doctor. Taking this medicine at the same times each day helps maintain a steady level of the treatment in your bloodstream. You can take this tablet with or without food, making it easy to incorporate into your daily routine. Making sensible adjustments, such as adopting a low-sodium diet and engaging in gentle, doctor-approved physical activity, can significantly support your treatment results.

While taking Bozetan 125mg Tablet, some patients may experience mild, common side effects such as headaches, joint pain, or cold-like symptoms. However, because this medication can cause serious liver damage, it is critical to consult your doctor immediately if you develop symptoms such as dark urine, yellowing of your skin or eyes, or severe nausea. Regular blood monitoring is required to ensure this medicine remains safe for you to use.

Bozetan 125mg Tablet is not suitable for everyone. Do not take this if you are pregnant, planning to become pregnant, or have moderate-to-severe liver damage. Before starting, you must tell your doctor if you have a history of anemia, fluid retention, or pre-existing liver issues, so they can evaluate whether this medication is safe for your specific condition.

This medicine can interact with several substances; for example, it may reduce the effectiveness of hormonal birth control, and combining it with alcohol can increase the risk of low blood pressure and liver strain. Special patient groups, including those who are breastfeeding, planning a pregnancy, or elderly, must consult their doctor to carefully weigh the risks and benefits before using this medication.

Uses of Bozetan 125mg Tablet

Bozetan 125mg Tablet is used in the treatment of high blood pressure in the lungs and related conditions. The detailed uses of Bozetan 125mg Tablet are as follows:

  • Pulmonary Arterial Hypertension (PAH): Bozetan 125mg Tablet helps by widening the blood vessels in your lungs, which lowers the high blood pressure in these arteries and makes it easier for your heart to pump blood.
  • Systemic Sclerosis with Digital Ulcers: In certain clinical situations, this medicine helps reduce the development of new, painful finger ulcers by improving localized blood flow in patients with systemic sclerosis.

Key Benefits

Bozetan 125mg Tablet provides meaningful physical relief by managing the underlying constriction of your pulmonary blood vessels. By keeping these blood vessels open, the medication helps reduce the daily physical limitations caused by pulmonary arterial hypertension.

  • Improved Daily Stamina: Patients frequently notice they can walk longer distances and perform routine daily activities with much less shortness of breath and fatigue.
  • Delayed Disease Progression: Regular use of this medication helps slow down the worsening of your condition, helping to reduce the likelihood of hospital visits related to your blood pressure.
  • Prevention of Painful Ulcers: For those managing systemic sclerosis, this treatment helps limit the formation of new, painful open sores on the fingers, preserving hand movement and comfort.
Side effects of Bozetan 125mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Directions for Use

  • Always take Bozetan 125mg Tablet exactly as your doctor has instructed. Do not change your dose or stop the medication on your own.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or split the tablet.
  • You may take this medication with or without food. Try to take your doses at the same times every day to maintain a consistent amount of medicine in your body.
  • Because of severe safety risks to unborn babies, female patients of childbearing potential must strictly follow all required safety and monthly pregnancy testing protocols before and during treatment.

How Bozetan 125mg Tablet Works

Bozetan 125mg Tablet works by blocking the action of a natural substance in your body called endothelin-1. Endothelin-1 is a powerful chemical that causes the blood vessels in your lungs to tighten, narrow, and become thick. In individuals with pulmonary arterial hypertension, the body produces too much of this chemical, which restricts blood flow and forces the heart to work much harder to pump blood through the lungs. By binding to specific receptors, Bozetan 125mg Tablet prevents endothelin-1 from tightening the vessels. This allows the blood vessels to relax and widen. As a result, blood pressure in the lungs decreases, oxygen-rich blood flows more easily, and the strain on your heart is significantly reduced.
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Alcohol

Unsafe

Bozetan 125mg Tablet should not be taken along with alcohol to avoid unpleasant side effects.

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Pregnancy

Unsafe

Bozetan 125mg Tablet is a category X pregnancy drug, and it can cause harm to the baby, so it should not be taken if you are pregnant or planning to get pregnant.

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Breast Feeding

Unsafe

Bozetan 125mg Tablet is known to pass through breast milk and may cause harm to the baby, so it should not be taken if you are breastfeeding.

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Driving

Caution

Bozetan 125mg Tablet may cause hypotension (low blood pressure), which may make you feel dizzy. If you feel dizzy, please do not drive a car.

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Liver

Caution

Bozetan 125mg Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Bozetan 125mg Tablet to be taken with caution, especially if you have or have had a kidney disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

Bozetan 125mg Tablet is not recommended for use in children.

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Heart

Safe if prescribed

Bozetan 125mg Tablet is generally safe for use in cardiac patients for the treatment of pulmonary arterial hypotension, if prescribed by the doctor.

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Geriatrics

Caution

Bozetan 125mg Tablet should be given with caution in elderly patients. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Bozetan 125mg Tablet

If you suspect an overdose or have taken too much Bozetan 125mg Tablet, you may experience a sharp drop in blood pressure, resulting in severe dizziness, rapid heart rate, or fainting. Seek immediate emergency medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Limit Sodium Consumption: Reduce your daily salt intake to help manage fluid retention and keep your blood pressure stable. Avoid heavily processed foods and do not add extra table salt to your meals.
  • Track Your Weight Daily: Weigh yourself every morning at the same time. Report any sudden weight gain of 2 to 3 pounds in a single day or 5 pounds in a week to your doctor, as this can be an early sign of fluid retention.
  • Stay Safe with Mild Exercise: Engage in gentle, doctor-approved physical activities, such as light walking. Avoid strenuous exercises, heavy lifting, or activities that require you to strain or hold your breath.
  • Use Reliable Double Contraception: If you are a female who can become pregnant, you must use two reliable methods of non-hormonal birth control simultaneously. Hormonal methods (like birth control pills) are not completely reliable on their own while taking this medicine.
health query

Have a query?

How Soon It Starts Working

  • The time required for Bozetan 125mg Tablet to start to work: The time required for Bozetan 125mg Tablet to show its action is not clinically established.
  • The time for which the effects of Bozetan 125mg Tablet last: The duration of action for Bozetan 125mg Tablet is not clinically established.

What if you forget to take Bozetan 125mg Tablet

If you miss a dose of Bozetan 125mg Tablet, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you struggle to remember your doses.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Complete Your Monthly Liver Tests: You must complete a liver function blood test every single month during your treatment, as Bozetan 125mg Tablet can cause severe liver damage.
  • Get Monthly Pregnancy Tests: Female patients of childbearing potential must have a negative pregnancy test before starting, every month during treatment, and for one month after stopping the medication.
  • Monitor Your Legs for Swelling: Inspect your feet and ankles daily for new or worsening fluid retention, and report any changes to your healthcare provider immediately.
  • Check Your Red Blood Cells: Ensure you complete your scheduled blood count tests, as your doctor will need to monitor your blood for signs of anaemia, particularly in the first few months of treatment.
  • Do Not Abruptly Discontinue: Do not stop taking Bozetan 125mg Tablet suddenly, as this can cause a rapid and dangerous worsening of your pulmonary hypertension symptoms.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Hormonal contraceptives (e.g., birth control pills, patches, vaginal rings, implants): Bozetan 125mg Tablet may reduce the effectiveness of these contraceptives, increasing the risk of an unplanned pregnancy.
  • Medicines used to suppress the immune system (e.g., Cyclosporine): Taking cyclosporine alongside Bozetan 125mg Tablet can significantly increase Bozetan 125mg Tablet levels in the blood, raising the risk of liver damage. This combination should be avoided.
  • Medicines used to treat diabetes (e.g., Glyburide): Combining glyburide with Bozetan 125mg Tablet may increase the risk of elevated liver enzymes and liver damage. This combination should be avoided.
  • Antifungal medicines (e.g., Ketoconazole): Taking ketoconazole with Bozetan 125mg Tablet may increase Bozetan 125mg Tablet levels in the body, potentially increasing the risk of side effects.
  • HIV medicines (e.g., Ritonavir): Ritonavir may increase the concentration of Bozetan 125mg Tablet in the bloodstream and may require dose adjustments or closer monitoring.
  • Antibiotics used to treat tuberculosis (e.g., Rifampin): Rifampin may decrease Bozetan 125mg Tablet levels in the blood, making the medicine less effective.

Drug-Food Interactions

  • Grapefruit and Grapefruit Juice: May interfere with how your body processes Bozetan 125mg Tablet, which can increase the level of medicine in your body and raise the risk of side effects.

Drug-Disease Interactions

  • Liver Disease: Do not take this medicine if you have moderate-to-severe liver impairment, as it can cause further liver damage.
  • Anaemia: If you have pre-existing low red blood cell levels, Bozetan 125mg Tablet may lower them further, requiring extra blood monitoring.
  • Fluid Retention or Heart Failure: This medicine can cause your body to retain fluid, which may worsen fluid buildup and place extra strain on a failing heart.
BosentanRegorafenib
Critical
BosentanCiclosporin
Critical

Drug-Drug Interactions

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BosentanRegorafenib
Critical
How does the drug interact with Bozetan 125mg Tablet:
Taking regorafenib with Bozetan 125mg Tablet it can increases the risk of side effects.

How to manage the interaction:
Taking Regorafenib with Bozetan 125mg Tablet is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
BosentanCiclosporin
Critical
How does the drug interact with Bozetan 125mg Tablet:
When Bozetan 125mg Tablet is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Ciclosporin with Bozetan 125mg Tablet is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
BosentanOlaparib
Severe
How does the drug interact with Bozetan 125mg Tablet:
Coadministration of olaparib and Bozetan 125mg Tablet may significantly reduce the blood levels of olaparib, making the medication less effective in treating your condition.

How to manage the interaction:
Taking Bozetan 125mg Tablet and Olaparib can lead to an interaction, but it can be taken if advised by your doctor. Do not stop using any medications without first talking to your doctor.
BosentanBedaquiline
Severe
How does the drug interact with Bozetan 125mg Tablet:
Taking bedaquiline with Bozetan 125mg Tablet ay reduce the blood levels of bedaquiline, which may decrease its effectiveness in treating your condition.

How to manage the interaction:
Although using Bozetan 125mg Tablet and Bedaquiline+ together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop using any medications without first talking to your doctor.
BosentanMedroxyprogesterone
Severe
How does the drug interact with Bozetan 125mg Tablet:
Taking Bozetan 125mg Tablet and Medroxyprogesterone may, reduce the blood levels and effects of Medroxyprogesterone.

How to manage the interaction:
Although there is a interaction between Bozetan 125mg Tablet and medroxyprogesterone, you can take these medicines together if prescribed by your doctor. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
BosentanDaclatasvir
Severe
How does the drug interact with Bozetan 125mg Tablet:
Bozetan 125mg Tablet can lower the levels of Daclatasvir in your blood, which could decrease its effectiveness in treating your condition.

How to manage the interaction:
Although using Bozetan 125mg Tablet and Daclatasvir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
BosentanUlipristal
Severe
How does the drug interact with Bozetan 125mg Tablet:
Bozetan 125mg Tablet can lower the levels of Ulipristal in your blood, which could decrease its effectiveness in treating your condition.

How to manage the interaction:
Although using Bozetan 125mg Tablet and Ulipristal together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting a doctor.
BosentanMipomersen
Severe
How does the drug interact with Bozetan 125mg Tablet:
Coadministration of Bozetan 125mg Tablet and mipomersen may increase the risk of liver problems.

How to manage the interaction:
Co-administration of Bozetan 125mg Tablet with Mipomersen can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
BosentanAxitinib
Severe
How does the drug interact with Bozetan 125mg Tablet:
Taking axitinib with Bozetan 125mg Tablet may significantly reduce the blood levels of axitinib, making the medication less effective in treating the condition.

How to manage the interaction:
Although using Bozetan 125mg Tablet and Axitinib together can result in an interaction, they can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
BosentanRanolazine
Severe
How does the drug interact with Bozetan 125mg Tablet:
Taking ranolazine and Bozetan 125mg Tablet together may significantly reduce the blood levels of ranolazine, making the medication less effective.

How to manage the interaction:
Although using Bozetan 125mg Tablet and Ranolazine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Bozetan 125mg Tablet is used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). Bozetan 125mg Tablet can even enhance our physical fitness, delay disease progression, and improve quality of life.
Bozetan 125mg Tablet is an anti-hypertension medication primarily used to treat‚ pulmonary arterial hypertension. It works by blocking the action of endothelin. Endothelin‚ narrows the blood vessels and increases the pressure in the blood vessels of the lungs. Bozetan 125mg Tablet helps to relax blood vessels by blocking endothelin and increasing the blood supply to the lungs.
Pulmonary arterial hypertension is a condition characterised by high pressure in the blood vessels that carry blood from the heart to the lungs. It can be due to constriction of blood vessels or some blockage in the blood vessel pathway.
Yes, in rare cases, $Name can cause anaemia. It can decrease your haemoglobin level, which may lead to anaemia. So, please regularly check your haemoglobin level if you are taking Bozetan 125mg Tablet.
It is usually taken with or without food. It should be swallowed as a whole with a glass of water; do not chew or crush it. Take it exactly as directed. Do not take more or less of it or more often than your doctor prescribes.
If you have liver problems, use Bozetan 125mg Tablet with caution and only under the guidance of your doctor. Patients with a history of liver disease should be closely monitored while taking Bozetan 125mg Tablet, as it may affect liver function. Your doctor may adjust the dosage or frequency of Bozetan 125mg Tablet based on your individual needs and medical condition.
No, you must not take Bozetan 125mg Tablet if you are pregnant or planning to become pregnant. This medicine can cause severe, life-threatening birth defects. If you suspect you are pregnant, stop taking the medication and contact your doctor immediately. Talk to your doctor for more information.
Common side effects of Bozetan 125mg Tablet may include swelling of legs and ankles, headaches, and diarrhoea in some cases. Most of these side effects of Bozetan 125mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Store in a cool and dry place away from sunlight. Keep Bozetan 125mg Tablet out of the sight and reach of children.
You need monthly blood tests because this medicine can cause liver damage and lower your red blood cell count. Regular testing allows your doctor to monitor your liver health and blood levels to make sure the medicine is safe for you to continue. Talk to your doctor if you have questions about these tests.
No, hormonal contraceptives like birth control pills are not reliable on their own while taking Bozetan 125mg Tablet, as this medicine makes them less effective. You must use two reliable, non-hormonal methods of birth control at the same time. Talk to your doctor to choose the best options for you.
It can take several weeks of daily, consistent use before you notice an improvement in your breathing and exercise capacity. It is important to keep taking the medicine as prescribed even if you do not feel immediate benefits. Talk to your doctor if your symptoms do not improve.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can expand your blood vessels, which may worsen dizziness or low blood pressure, and it can also increase stress on your liver. Talk to your doctor about your alcohol use.
Swelling in your ankles, feet, or legs is a known side effect that indicates fluid retention. You should weigh yourself daily and report any sudden weight gain or worsening swelling to your doctor right away, as they may need to adjust your therapy. Talk to your doctor if you notice these changes.
No, you must not stop taking Bozetan 125mg Tablet suddenly, even if you feel completely fine. Stopping this medication abruptly can cause your pulmonary hypertension symptoms to return or worsen rapidly. Any changes to your dose must be guided gradually by your healthcare provider. Talk to your doctor before making any changes.
No, Bozetan 125mg Tablet does not cure pulmonary arterial hypertension, but it helps manage the condition by keeping blood vessels relaxed, improving your daily physical capabilities, and slowing down the progression of the disease. It is a long-term treatment. Talk to your doctor to understand your long-term treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Center for Biotechnology Information (NCBI). Bosentan Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.10161 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Electronic Medicines Compendium (EMC). Pil.820 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  5. MedlinePlus. A605001 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  6. Bosentan Bosentan. 2013. [Accessed on 01 Apr. 2019]Check here
  7. Bosentan Bosentan. 2001. [Accessed on 23 Jan. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Shreya House, 301/A, Pereira Hill Road, Andheri East, Mumbai - 400 099, India
Other Info - BO41422
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