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compositionComposition:BRIVARACETAM-50MG
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Prescription Medicine
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Brivahenz 50Mg/5Ml Inj is used to treat Partial-onset seizures. It contains Brivaracetam, which reduces the electrical impulses and decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures. Common side effects include somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea, and vomiting. Inform your doctor if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BRIVARACETAM-50MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Brivahenz 50Mg/5Ml Inj

Brivahenz 50Mg/5Ml Inj is a prescription intravenous medicine used to treat partial-onset seizures in adults and children. In many countries, the intravenous formulation is approved for patients 4 years of age and older when oral treatment is temporarily not feasible. It helps control abnormal electrical activity in the brain and is commonly used when oral levetiracetam cannot be taken temporarily, such as during hospitalisation, surgery, or when swallowing is difficult. This medicine helps maintain seizure control until oral treatment can be resumed.

To achieve the best results, you should receive Brivahenz 50Mg/5Ml Inj exactly as prescribed by your doctor, usually twice daily at evenly spaced intervals. Since it is administered directly into a vein, food does not affect its absorption. Maintaining a regular sleep schedule, managing stress, and taking your seizure medicines consistently can further improve seizure control.

While receiving this medicine, you may experience mild side effects such as drowsiness, dizziness, headache, or nausea. However, seek immediate medical attention if you develop severe mood changes, depression, suicidal thoughts, severe allergic reactions, or difficulty breathing.

Before receiving this medicine, tell your doctor if you have kidney disease, liver disease, depression, or any other mental health condition. Do not receive this medicine if you have previously experienced a severe allergic reaction (hypersensitivity) to Brivahenz 50Mg/5Ml Inj or any of its ingredients (excipients). Tell your doctor if you have ever had an allergic reaction to this medicine. 

This medicine may interact with alcohol and other medicines that cause drowsiness, increasing the risk of excessive sleepiness and impaired alertness. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor before starting treatment to ensure this medicine is appropriate for you.

Uses of Brivahenz 50Mg/5Ml Inj

Your doctor may prescribe Brivahenz 50Mg/5Ml Inj to treat the following condition:

  • Partial-onset seizures: Helps reduce the frequency and severity of focal seizures by controlling abnormal electrical activity in the brain.

Key Benefits

Brivahenz 50Mg/5Ml Inj helps provide reliable seizure control when oral medication cannot be taken. Because it is administered directly into a vein, it maintains therapeutic drug levels quickly, helping prevent breakthrough seizures during hospitalisation or temporary inability to swallow medicines.

  • Maintains seizure control: Helps prevent partial-onset seizures when oral treatment is temporarily not possible.
  • Rapid and reliable treatment: Direct intravenous administration allows the medicine to begin working quickly without depending on absorption through the digestive tract.
  • Supports uninterrupted epilepsy management: Ensures continuous seizure treatment during surgery, severe illness, or recovery until oral medication can be restarted.
  • Helps reduce seizure-related complications: Consistent seizure control lowers the risk of injury, prolonged seizures, and disruption to daily activities.
Side effects of Brivahenz 50Mg/5Ml Inj
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Brivahenz 50Mg/5Ml Inj will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Brivahenz 50Mg/5Ml Inj Works

Brivahenz 50Mg/5Ml Inj contains brivaracetam, belongs to a class of medicines called antiepileptic drugs (AEDs). It works by binding to a protein in the brain called synaptic vesicle protein 2A (SV2A), which helps regulate communication between nerve cells. By modifying the release of chemical messengers between neurons, Brivahenz 50Mg/5Ml Inj stabilises abnormal electrical activity in the brain and reduces the likelihood of uncontrolled nerve firing that leads to seizures. This helps prevent seizures while allowing normal brain function to continue.
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects, such as dizziness and sleepiness.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Inform your doctor before receiving Brivahenz 50Mg/5Ml Inj if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There has been no significant research on using Brivahenz 50Mg/5Ml Inj in breastfeeding/nursing moms. So, let your doctor know if you are a nursing mother before taking Brivahenz 50Mg/5Ml Inj; your doctor will decide whether Brivahenz 50Mg/5Ml Inj can be taken by breastfeeding mothers.

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Driving

Unsafe

Brivahenz 50Mg/5Ml Inj may cause somnolence (excess sleepiness) and fatigue (feeling overtired). It impacts your daily activities; hence, avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Dose adjustments are recommended for patients with hepatic impairment. So inform your doctor before receiving Brivahenz 50Mg/5Ml Inj if you have a history of liver impairments.

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Kidney

Caution

Brivahenz 50Mg/5Ml Inj is recommended not to be used in end-stage renal disease patients undergoing dialysis. Inform your doctor before receiving Brivahenz 50Mg/5Ml Inj if you have a history of kidney diseases/conditions.

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Children

Safe if prescribed

Brivahenz 50Mg/5Ml Inj is safe for use in children if prescribed by the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Heart

Safe if prescribed

Brivahenz 50Mg/5Ml Inj is generally considered safe for heart patients. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Brivahenz 50Mg/5Ml Inj is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Brivahenz 50Mg/5Ml Inj

Because this medicine is administered under medical supervision, overdose is uncommon. However, if an overdose is suspected, seek immediate medical attention. Symptoms may include extreme drowsiness, confusion, agitation, slowed breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Maintain a regular sleep schedule: Sleep deprivation can increase the risk of seizures.
  • Avoid alcohol: Alcohol may reduce seizure control and increase dizziness and drowsiness.
  • Take seizure medicines consistently: Never skip doses or stop treatment without consulting your doctor.
  • Manage stress: Practice relaxation techniques such as meditation, yoga, or deep breathing, as stress can trigger seizures.
  • Keep a seizure diary: Record seizure episodes, possible triggers, and medication adherence to help your doctor optimize treatment.
health query

Have a query?

How Soon It Starts Working

The time required for Brivahenz 50Mg/5Ml Inj to start to work: The exact onset time of Brivahenz 50Mg/5Ml Inj has not been clinically established.

The time for which the effects of Brivahenz 50Mg/5Ml Inj last: The duration of Brivahenz 50Mg/5Ml Inj’s effect is clinically not established.

What if you forget to take Brivahenz 50Mg/5Ml Inj

Because this medicine is usually administered by a healthcare professional, missed doses are uncommon. If you miss an appointment for your injection, contact your healthcare provider as soon as possible to arrange another appointment. Do not receive a double dose to make up for a missed dose.

Storage

• Store Brivahenz 50Mg/5Ml Inj at controlled room temperature, ideally between 15°C and 30°C.

Drug Warnings

  • Inspect the solution: Do not use the injection if it appears cloudy, discoloured, or contains visible particles.
  • Do not stop treatment suddenly: Abrupt discontinuation may increase the risk of seizures or status epilepticus.
  • Monitor mood changes: Inform your doctor immediately if you experience depression, anxiety, aggression, or suicidal thoughts.
  • Avoid driving until you know its effects: This medicine may cause dizziness or drowsiness, especially when treatment is started.
  • Keep follow-up appointments: Regular monitoring helps your doctor assess seizure control and determine when to transition back to oral medication.

Drug-Drug Interactions

verifiedApollotooltip
  • Sedatives, opioid pain medicines, sleeping pills, or anti-anxiety medicines: May increase drowsiness, dizziness, and impaired alertness.
  • Methotrexate: No clinically significant interaction has been established with Brivahenz 50Mg/5Ml Inj. Always inform your doctor about all medicines you are taking so they can assess potential interactions.
  • Other antiepileptic medicines: Although significant interactions are uncommon, dose adjustments may occasionally be required based on clinical response.
BrivaracetamKetamine
Severe
BrivaracetamEsketamine
Severe

Drug-Drug Interactions

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BrivaracetamKetamine
Severe
How does the drug interact with Brivahenz 50Mg/5Ml Inj:
Co-administration of Brivahenz 50Mg/5Ml Inj with Ketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is a possible interaction between Brivahenz 50Mg/5Ml Inj and Ketamine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - feeling dizzy, sleepy, confused, having trouble focusing, feeling too relaxed, or having trouble breathing - make sure to contact adoctor right away. Do not stop using any medications without talking to a doctor.
BrivaracetamEsketamine
Severe
How does the drug interact with Brivahenz 50Mg/5Ml Inj:
Co-administration of Brivahenz 50Mg/5Ml Inj with Esketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is an interaction, Brivahenz 50Mg/5Ml Inj can be taken with Esketamine if prescribed by the doctor. Consult the prescriber if you notice drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not discontinue the medication without consulting a doctor

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol during treatment, as it may increase drowsiness, impair coordination, and reduce seizure control.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

[ANTICONVULSANT]

FAQs

Brivahenz 50Mg/5Ml Inj is used to treat Partial-onset seizures.
Brivahenz 50Mg/5Ml Inj contains Brivaracetam, an antiepileptic, which works by suppressing the abnormal activity in the brain and prevents the spread of electrical signals that cause seizures.
To treat your condition effectually, continue taking Brivahenz 50Mg/5Ml Inj for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Brivahenz 50Mg/5Ml Inj; your doctor will gradually reduce the dose to avoid precipitating seizures.
Brivahenz 50Mg/5Ml Inj may cause suicidal thoughts such as killing or harming yourself. People taking Brivahenz 50Mg/5Ml Inj should be closely monitored for suicidal thoughts or behaviour. Speak with your doctor immediately if you need to.
Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.
Brivahenz 50Mg/5Ml Inj intravenous injection is typically administered by a trained healthcare professional in a hospital or clinical setting. Home administration is not routine and should only occur if specifically recommended and supervised by your healthcare team in accordance with local medical practice.
Mild drowsiness is a common side effect when starting Brivahenz 50Mg/5Ml Inj. Avoid driving or performing tasks that require alertness until you know how the medicine affects you. Talk to your doctor if the sleepiness does not improve.
Because it is injected directly into a vein, Brivahenz 50Mg/5Ml Inj enters your bloodstream immediately and starts working quickly to help stabilise brain activity. Talk to your doctor for more details about your specific response.
Seizure control is vital during pregnancy, but Brivahenz 50Mg/5Ml Inj should only be used if the potential benefits outweigh the risks. If you are pregnant or planning to become pregnant, talk to your doctor immediately.
Yes, some people using Brivahenz 50Mg/5Ml Inj may experience mood changes, irritability, or depression. If you or your family notice any unusual behavioural changes, contact your doctor right away.
Yes, Brivahenz 50Mg/5Ml Inj can interact with certain other seizure drugs. Your doctor will review your complete medication list to ensure all your treatments work safely together. Talk to your doctor or pharmacist.
Do not use the injection if the liquid is cloudy, discoloured, or contains any particles. Discard the vial safely and use a new one. Talk to your pharmacist if you need advice on replacement vials.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 205836S009,205837S007,205838S006Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Levetiracetam Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Brivaracetam Prescribing Information Nov 17 - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Brivaracetam Brivaracetam. 2016. [Accessed on 20 Mar. 2019]Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 19 Feb. 2020]Check here
  6. Briviact 100 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 27 July 2022]Check here
  7. DailyMed - BRIVIACT- brivaracetam tablet, film coatedBRIVIACT- brivaracetam solutionBRIVIACT- brivaracetam injection, suspension [Internet]. Dailymed.nlm.nih.gov. 2022 [Accessed on 27 July 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - BRI0675

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