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compositionComposition:BRIVARACETAM-10MG
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Brivazen Injection 5 ml is used to treat Partial-onset seizures. It contains Brivaracetam, which reduces the electrical impulses and decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures. Common side effects include somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea, and vomiting. Inform your doctor if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BRIVARACETAM-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Brivazen Injection 5 ml

Brivazen Injection 5 ml belongs to a group of medications called 'anti-convulsants'. It is used for treating partial-onset seizures (seizures involving only one part of the brain) in people with epilepsy (fits) in patients one month of age and older.

Brivazen Injection 5 ml contains Brivaracetam, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Brivazen Injection 5 ml decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures.

In some cases, you may experience side effects such as sleepiness, dizziness, fatigue, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Let your doctor know about all your medical conditions, sensitivities, and medications you are using to prevent any potential interactions. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Brivazen Injection 5 ml

Brivazen Injection 5 ml is used in the treatment of Partial-onset seizures. The detailed use of Brivazen Injection 5 ml is as follows:

  • Treat partial-onset seizures: Brivazen Injection 5 ml is used as an adjunctive therapy to control partial-onset seizures in patients with epilepsy. It works by stabilising electrical activity and reducing seizure frequency.

Key Benefits

  • Brivazen Injection 5 ml is an anticonvulsant (anti-epileptic) medication used for the treatment of partial-onset seizures associated with epilepsy.
  • It provides fast and effective seizure management, particularly useful in situations where oral administration is not possible or practical.
  • Brivazen Injection 5 ml works by suppressing abnormal electrical impulses that lead to seizures.
  • It helps provide reliable and timely control of seizures, improving patient stability and quality of life.
Side effects of Brivazen Injection 5 ml
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Brivazen Injection 5 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Brivazen Injection 5 ml Works

Brivazen Injection 5 ml contains Brivaracetam, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Brivazen Injection 5 ml decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures.
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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects, such as dizziness and sleepiness.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Inform your doctor before receiving Brivazen Injection 5 ml if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There has been no significant research on using Brivazen Injection 5 ml in breastfeeding/nursing moms. So, let your doctor know if you are a nursing mother before taking Brivazen Injection 5 ml; your doctor will decide whether Brivazen Injection 5 ml can be taken by breastfeeding mothers.

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Driving

Unsafe

Brivazen Injection 5 ml may cause somnolence (excess sleepiness) and fatigue (feeling overtired). It impacts your daily activities; hence, avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Dose adjustments are recommended for patients with hepatic impairment. So inform your doctor before receiving Brivazen Injection 5 ml if you have a history of liver impairments.

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Kidney

Caution

Brivazen Injection 5 ml is recommended not to be used in end-stage renal disease patients undergoing dialysis. Inform your doctor before receiving Brivazen Injection 5 ml if you have a history of kidney diseases/conditions.

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Children

Safe if prescribed

Brivazen Injection 5 ml is safe for use in children if prescribed by the doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Heart

Safe if prescribed

Brivazen Injection 5 ml is generally considered safe for heart patients. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Brivazen Injection 5 ml is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Brivazen Injection 5 ml

An overdose of Brivazen Injection 5 ml may cause somnolence and dizziness. Since Brivazen Injection 5 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or you are experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try to reduce or avoid them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.
health query

Have a query?

How Soon It Starts Working

The time required for Brivazen Injection 5 ml to start to work: The exact onset time of Brivazen Injection 5 ml has not been clinically established.

The time for which the effects of Brivazen Injection 5 ml last: The duration of Brivazen Injection 5 ml’s effect is clinically not established.

What if you forget to take Brivazen Injection 5 ml

As this medication will be administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep Brivazen Injection 5 ml out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not use Brivazen Injection 5 ml if you are allergic to any of its components.
  • Let your doctor know about all your medical conditions and all medications you are using.
  • Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Consult your doctor immediately if you experience suicidal tendencies.
  • It is recommended not to drive or operate machinery as Brivazen Injection 5 ml may cause tiredness and fatigue.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Brivazen Injection 5 ml may interact with other anticonvulsants (carbamazepine, phenytoin, levetiracetam), antibiotics (rifampin), opioid analgesics (buprenorphine, propoxyphene), anaesthetics (ketamine/esketamine) and medications used to treat narcolepsy (sodium oxybate)

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have liver/kidney impairment, suicidal tendency or ideation or lactose intolerance.

BrivaracetamKetamine
Severe
BrivaracetamEsketamine
Severe

Drug-Drug Interactions

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BrivaracetamKetamine
Severe
How does the drug interact with Brivazen Injection 5 ml:
Co-administration of Brivazen Injection 5 ml with Ketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is a possible interaction between Brivazen Injection 5 ml and Ketamine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - feeling dizzy, sleepy, confused, having trouble focusing, feeling too relaxed, or having trouble breathing - make sure to contact adoctor right away. Do not stop using any medications without talking to a doctor.
BrivaracetamEsketamine
Severe
How does the drug interact with Brivazen Injection 5 ml:
Co-administration of Brivazen Injection 5 ml with Esketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is an interaction, Brivazen Injection 5 ml can be taken with Esketamine if prescribed by the doctor. Consult the prescriber if you notice drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not discontinue the medication without consulting a doctor

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

[ANTICONVULSANT]

FAQs

Brivazen Injection 5 ml is used to treat Partial-onset seizures.
Brivazen Injection 5 ml contains Brivaracetam, an antiepileptic, which works by suppressing the abnormal activity in the brain and prevents the spread of electrical signals that cause seizures.
To treat your condition effectually, continue taking Brivazen Injection 5 ml for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Brivazen Injection 5 ml; your doctor will gradually reduce the dose to avoid precipitating seizures.
Brivazen Injection 5 ml may cause suicidal thoughts such as killing or harming yourself. People taking Brivazen Injection 5 ml should be closely monitored for suicidal thoughts or behaviour. Speak with your doctor immediately if you need to.
Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 205836S009,205837S007,205838S006Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Levetiracetam Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Brivaracetam Prescribing Information Nov 17 - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Brivaracetam Brivaracetam. 2016. [Accessed on 20 Mar. 2019]Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 19 Feb. 2020]Check here
  6. Briviact 100 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 27 July 2022]Check here
  7. DailyMed - BRIVIACT- brivaracetam tablet, film coatedBRIVIACT- brivaracetam solutionBRIVIACT- brivaracetam injection, suspension [Internet]. Dailymed.nlm.nih.gov. 2022 [Accessed on 27 July 2022]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - BRI0564

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