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Calcium Gluconate is indicated for pediatric and adult patients to treat several medical conditions caused by low levels of Calcium in the body (hypocalcemia). It contains calcium gluconate, which is administered to increase calcium's blood levels in the body, thereby reducing the risk of calcium disorders due to a lack of calcium in the body. The most common adverse reactions of Calcium Gluconate are local soft tissue inflammation, vasodilation, decreased blood pressure, bradycardia, cardiac arrhythmia, syncope, and cardiac arrest.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Calcium Gluconate

Calcium Gluconate is a specialised injection used to treat dangerously low calcium levels in the blood, which can cause severe muscle spasms and nerve issues. It is also given in medical emergencies to protect the heart from high potassium levels or to treat magnesium poisoning. This medication helps rapidly restore vital mineral balance in the body when oral treatments are not fast or effective enough.

This injection is typically given as a single dose or repeated at specific intervals depending on your blood test results and clinical response. Because it is a liquid delivered directly into a vein, it does not rely on food intake, but staying hydrated and eating mineral-rich foods can support your recovery. Your doctor will determine the exact schedule based on how well your body maintains its mineral levels.

While receiving this treatment, you may experience mild, temporary reactions like a warm flushing feeling or a chalky taste in your mouth. However, you must inform your healthcare provider immediately if you experience severe symptoms like an irregular heart rate, chest pain, or severe burning at the injection site. These serious reactions require quick attention to ensure your safety.

Before receiving Calcium Gluconate, it is important to discuss your medical history with your doctor, especially if you have kidney disease, heart problems, or a history of kidney stones. Do not take this if you already have excessively high calcium levels in your blood or urine. Your doctor will run blood tests beforehand to confirm this treatment is safe for you.

This injection can interact with certain medications, such as heart medicines like digoxin or water pills, which can cause dangerous mineral imbalances. Pregnant women, breastfeeding mothers, and elderly individuals should consult their doctor before receiving this treatment to ensure it is handled with extra caution.

Uses of Calcium Gluconate

Your doctor may prescribe Calcium Gluconate to treat the following conditions:

  • Severely low blood calcium (hypocalcemia): It rapidly raises mineral levels in your blood to stop painful muscle spasms, cramps, and numbness.
  • High blood potassium (hyperkalemia): It helps protect the heart from dangerous rhythm changes caused by excessive potassium levels.
  • Magnesium toxicity: It acts as an antidote to reverse the life-threatening effects of too much magnesium in the body.

Key Benefits

This injection provides rapid, life-saving benefits in critical situations by delivering nutrients directly to where they are needed most.

  • Rapid relief from muscle spasms: By quickly restoring mineral levels, it relieves painful muscle cramping, tetany, and numbness almost instantly.
  • Vital heart protection: It stabilises the electrical activity of the heart muscle during emergencies caused by high potassium or magnesium levels, preventing dangerous arrhythmias.
  • Direct absorption: Because it bypasses the digestive system entirely, it is highly effective for patients who cannot swallow pills or who have severe absorption issues in their gut.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Calcium Gluconate will be administered in the hospital setting by a trained healthcare professional.
  • Do not self-administer.

How Calcium Gluconate Works

Calcium Gluconate contains calcium gluconate. Calcium Gluconate works by delivering essential mineral ions directly into your bloodstream. These ions are immediately absorbed by the surrounding tissues, raising the concentration of vital minerals to normal levels. By restoring this balance, the medicine stabilises the membranes of your nerves and muscle cells, particularly in your heart. This prevents abnormal electrical signals and helps your muscles contract and relax normally.
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Alcohol

Caution

Avoid consumption of alcohol while on treatment with this medicine.

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Pregnancy

Caution

Calcium Gluconate should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before recommending Calcium Gluconate.

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Breast Feeding

Caution

Calcium Gluconate should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before recommending Calcium Gluconate.

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Driving

Safe

Calcium Gluconate will not affect your ability to drive.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Calcium Gluconate. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney conditions, inform your doctor before taking Calcium Gluconate. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Safe if prescribed

Please consult your doctor. Your doctor will weigh the risks and benefits before prescribing this medicine to your child.

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Heart

Caution

Calcium Gluconate can be used in patients with heart problems, but only under strict medical supervision. It may cause arrhythmias, especially with digoxin, so heart monitoring during administration is essential.

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Geriatrics

Caution

Geriatric patients can receive Calcium Gluconate, but they may be more sensitive to its effects. Careful dosing and heart monitoring are essential to avoid complications like arrhythmias or hypotension.

What if I have taken an overdose of Calcium Gluconate

Because this medication is given under professional medical supervision, an overdose is rare. However, if you experience symptoms like extreme thirst, muscle weakness, confusion, severe nausea, or an irregular heartbeat during or shortly after your treatment, tell your healthcare provider immediately. Emergency medical staff are trained to manage high mineral levels quickly.

Diet & Lifestyle Advise

  • Prioritise Vitamin D: Eat foods rich in vitamin D, such as fatty fish, egg yolks, and fortified cereals, to help your body absorb and utilise minerals more effectively.
  • Incorporate mineral-dense foods: Unless advised otherwise by your doctor, include natural dietary sources of calcium like yoghurt, cheese, leafy greens, and almonds into your daily meals.
  • Avoid mineral blockers: Limit your consumption of sodas, excessive caffeine, and foods high in oxalates (like spinach or rhubarb) in the hours surrounding your treatment, as these can interfere with mineral retention.
  • Stay adequately hydrated: Drink plenty of water daily to support your kidney function, which is essential for filtering and balancing minerals in your body.
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How Soon It Starts Working

The time required for Calcium Gluconate to start to work: The peak effect of Calcium Gluconate is seen within 3 minutes of administration. The time for which the effects of Calcium Gluconate last: Calcium Gluconate effect lasts for 30-60 minutes.

What if you forget to take Calcium Gluconate

Since this injection is usually given by a healthcare provider in a clinical setting, it is unlikely that you will miss a dose. If you miss a scheduled appointment for your infusion, contact your clinic or healthcare provider immediately to reschedule and keep your mineral levels stable.

Storage

•This medication must be stored properly to maintain its safety and effectiveness. It should be kept at room temperature, strictly between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the liquid: Always visually check the vial before use; if the solution is cloudy, colored, or contains particles, do not inject it.
  • Inject very slowly: Ensure your healthcare provider injects the solution slowly, as rapid injection into the vein can lead to sudden drops in blood pressure or heart rhythm complications.
  • Monitor the injection site: If you feel any burning, stinging, coldness, or swelling around your IV line during the injection, notify your nurse immediately to prevent severe tissue damage.
  • Rotate injection sites: If you require repeated injections, work with your medical team to rotate the injection sites to reduce the risk of vein irritation or scarring.
  • Keep testing appointments: Attend all scheduled blood and urine tests so your doctor can track your mineral levels and prevent them from getting too high.

Drug-Drug Interactions

verifiedApollotooltip
  • Digoxin: Combining this injection with digoxin can severely increase the risk of life-threatening irregular heartbeats.
  • Thiazide diuretics: These water pills reduce how much mineral is cleared through your urine, which can lead to dangerously high levels of calcium in your blood.
  • Ceftriaxone: Mixing this injection with the antibiotic ceftriaxone in the same IV line can cause dangerous, solid crystals to form, which can damage vital organs.

Drug-Drug Interactions

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How does the drug interact with Calcium Gluconate 10 ml 10 ml:
Co-administration of Calcium Gluconate 10 ml with Ceftriaxone can increase the risk of adverse effects.

How to manage the interaction:
Taking Ceftriaxone with Calcium Gluconate 10 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Calcium Gluconate 10 ml 10 ml:
Co-administration of Calcium Gluconate 10 ml with Digoxin may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium Gluconate 10 ml can be taken with Digoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Calcium Gluconate 10 ml 10 ml:
Co-administration of Eltrombopag and Calcium Gluconate 10 ml may interfere with the absorption of Eltrombopag and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Calcium Gluconate 10 ml can be taken with Eltrombopag if prescribed by the doctor. However, take eltrombopag on an empty stomach, i.e., 2 hours before or 4 hours after taking Calcium Gluconate 10 ml. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Calcium Gluconate 10 ml 10 ml:
Co-administration of Dolutegravir and Calcium Gluconate 10 ml may interfere with the absorption of Dolutegravir and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Calcium Gluconate 10 ml can be taken with Dolutegravir if prescribed by the doctor. However, take dolutegravir 2 hours before or 6 hours after taking Calcium Gluconate 10 ml. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Calcium Gluconate 10 ml 10 ml:
Co-administration of Calcium Gluconate 10 ml with Digitoxin may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium Gluconate 10 ml can be taken with digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Calcium Gluconate when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MINERALS]

FAQs

Calcium Gluconate is indicated for pediatric and adult patients to treat several medical conditions caused by low levels of Calcium in the body (hypocalcemia).
Calcium Gluconate contains Calcium Gluconate, which is administered to increase Calcium's blood levels in the body, thereby reducing the risk of calcium disorders due to lack of Calcium in the body.
Calcium Gluconate is a mineral salt, which is administered to increase blood calcium levels in the body. It is used to treat the body's calcium deficiency (hypocalcemia), thereby reducing the risk of calcium disorders due to low calcium levels.
Calcium Gluconate can be used in the treatment of lead and fluoride poisoning.
Calcium Gluconate is to help restore normal heart function in an emergency (cardiac arrest) if potassium levels in the blood are too high.
Yes, Calcium Gluconate is safe and good for your health when used as advised by the doctor. Calcium Gluconate makes your bones strong and healthy by increasing calcium levels in your body. It reduces the risk of bone disorders like osteoporosis, making your bones less likely to fracture or break.
Do not use Calcium Gluconate if you are allergic to any of its components or if you already have high calcium levels in your blood. Your doctor will likely order a blood test before starting treatment to ensure it's safe for you.
High calcium levels in the blood and urine can cause health problems, including muscle weakness, kidney issues, constipation, nausea, weight loss, fatigue, and abnormal heart rhythms. If you're experiencing any of these symptoms, it's essential to consult your doctor immediately.
The calcium needs vary by age and gender. Teens need 1,300 mg daily, while adults need 1,000 mg until age 50. After 50, men need 1,000 mg, whereas women need 1,200 mg. However, your individual needs may differ, so it's best to consult your doctor for personalized advice.
When taking Calcium Gluconate, avoid taking antacids that contain calcium at the same time. Instead, maintain a gap of at least 2 hours between Calcium Gluconate and antacids to ensure safe and effective treatment.
It is not recommended to take antibiotics along with Calcium Gluconate as it might affect the absorption of other medicines. You are recommended to consult your doctor before taking antibiotics along with Calcium Gluconate.
Calcium Gluconate should be used during breastfeeding only if prescribed by your doctor as it is unknown whether the medication passes into the breastmilk. You are recommended to consult your doctor before using Calcium Gluconate during breastfeeding.
Calcium is a vital mineral that helps build strong bones and teeth and supports many bodily functions. Calcium also helps your body regulate hormones & aids muscle and nerve function.
Get your daily calcium fix from dairy foods like milk, yogurt, and cheese, as well as calcium-fortified soy products. You can also find smaller amounts of calcium in leafy green vegetables like kale and broccoli and in nuts and seeds like almonds and sesame seeds. These foods will help keep your bones strong and healthy.
The common side effects of Calcium Gluconate may include local soft tissue inflammation, nausea, vomiting, sweating, and hot flushes. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, this medication must only be injected slowly into a vein. Injecting it into a muscle or under the skin can cause severe irritation, pain, and serious tissue damage. Talk to your doctor.
Because it is injected directly into your bloodstream, this medication starts working almost immediately to restore mineral balance and protect your heart. Talk to your doctor.
Some people may experience mild dizziness or flushing immediately after the injection. It is best to wait and see how you feel before attempting to drive or operate machinery. Talk to your doctor.
Rapid changes in blood mineral levels can directly affect your heart rhythm. Monitoring ensures that the medication is injected at a safe rate and your heart remains stable. Talk to your doctor.
You are more likely to feel a warm sensation or flushing in your arm and body during the injection. If you feel sudden pain, swelling, or extreme coldness, tell your nurse right away. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Hansraj College, University Of Delhi, Delhi-110007 India
Other Info - CAL0029
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