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compositionComposition:CALCITONIN-200IU
prescription
Prescription Medicine
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Caldox Nasal Spray 30 MDI is used to treat Postmenopausal osteoporosis. It contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus, it helps to treat osteoporosis in postmenopausal women. Common side effects of Caldox Nasal Spray 30 MDI are hypocalcemia, runny nose, nosebleed, sinus pain, application site reactions such as rhinitis (stuffy nose), epistaxis (nose bleeds) and other nasal symptoms, back pain, arthralgia (Joint pain) and headache.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CALCITONIN-200IU

Manufacturer/Marketer :

Sanatra Healthcare Ltd

Consume Type :

Nasal

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Caldox Nasal Spray 30 MDI

Caldox Nasal Spray 30 MDI is a prescription nasal spray used to treat osteoporosis in women who have been postmenopausal for at least five years when other osteoporosis treatments are not suitable or cannot be tolerated. It helps slow bone loss, maintain bone strength, and reduce the risk of vertebral (spinal) fractures.

To achieve the best results, you should use Caldox Nasal Spray 30 MDI exactly as prescribed by your doctor. The spray is administered into one nostril each day, alternating nostrils with each dose. It can be used without regard to meals. Maintaining an adequate intake of calcium and vitamin D, together with regular weight-bearing exercise, can further support healthy bones during treatment.

While using this medicine, you may experience mild nasal symptoms such as a runny nose, nasal irritation, or congestion. These effects are usually temporary. However, contact your doctor immediately if you develop persistent nosebleeds, severe nasal sores, or signs of a severe allergic reaction.

Do not use this medicine if you have a known allergy to Caldox Nasal Spray 30 MDI or any of its ingredients. Tell your doctor before starting treatment if you have low blood calcium levels or ongoing nasal conditions such as chronic rhinitis, nasal ulcers, or a deviated nasal septum, as these conditions may affect treatment.

This medicine may interact with certain medications, including lithium. If you are taking other medicines or have any long-term medical conditions, inform your doctor before starting treatment. This medicine is intended only for postmenopausal women and should not be used during pregnancy or breastfeeding.
 

Uses of Caldox Nasal Spray 30 MDI

Your doctor may prescribe Caldox Nasal Spray 30 MDI to treat the following condition:

  • Postmenopausal osteoporosis: Helps slow bone loss and reduce the risk of vertebral (spinal) fractures in women who have been postmenopausal for at least five years and cannot use other osteoporosis treatments.

Key Benefits

Caldox Nasal Spray 30 MDI helps preserve bone strength by slowing the breakdown of bone tissue in women with postmenopausal osteoporosis.

  • Slows bone loss: Helps reduce the rate at which bone is broken down, supporting healthier bones.
  • Reduces the risk of spinal fractures: Lowers the likelihood of vertebral fractures associated with osteoporosis.
  • Convenient nasal administration: Provides an alternative treatment option for people who cannot tolerate oral osteoporosis medicines.
  • Supports long-term bone health: When combined with adequate calcium, vitamin D, and regular exercise, it helps maintain bone strength and mobility.
  • Suitable when other therapies are unsuitable: May be considered when first-line osteoporosis medicines cannot be used because of side effects or contraindications.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Remove the cap of the bottle, insert the tip into a nostril while closing the other nostril, and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.
  • Wipe the nozzle with a clean tissue and replace the cap after each use.

How Caldox Nasal Spray 30 MDI Works

Caldox Nasal Spray 30 MDI contains calcitonin, a hormone that helps regulate calcium balance and bone metabolism. It works by reducing the activity of osteoclasts, the cells responsible for breaking down bone tissue. By slowing bone resorption, Caldox Nasal Spray 30 MDI helps preserve bone mineral density and reduce the risk of fractures, particularly in the spine.
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Alcohol

Caution

Consuming alcohol is not advisable; it affects how the body absorbs calcium and vitamin D, both of which are essential for good bone formation.

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Pregnancy

Not applicable

Caldox Nasal Spray 30 MDI is intended for postmenopausal women only. So, it is not recommended for use in pregnancy.

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Breast Feeding

Not applicable

Caldox Nasal Spray 30 MDI is intended for postmenopausal women only. So, it is not recommended for use in breastfeeding women.

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Driving

Safe

Caldox Nasal Spray 30 MDI does not impact your ability to drive or operate machinery.

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Liver

Caution

Limited information is available on the use of Caldox Nasal Spray 30 MDI in patients with liver disease. Inform your doctor before receiving the Caldox Nasal Spray 30 MDI if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information is available about using Caldox Nasal Spray 30 MDI in patients with liver disease. Inform your doctor before receiving the Caldox Nasal Spray 30 MDI if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Not applicable

Caldox Nasal Spray 30 MDI is intended for postmenopausal women only. So, it is recommended not to use it in children.

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Heart

Caution

Caldox Nasal Spray 30 MDI should be used with caution in patients with heart disease. Please consult the doctor if you have heart problems.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Caldox Nasal Spray 30 MDI to geriatric patients. Your doctor will prescribe Caldox Nasal Spray 30 MDI if the benefits outweigh the risks.

What if I have taken an overdose of Caldox Nasal Spray 30 MDI

An overdose is unlikely when used as directed. However, if too much medicine is used or the nasal solution is accidentally swallowed, contact your doctor or seek medical attention for further advice.

Diet & Lifestyle Advise

  • Maintain adequate calcium and vitamin D intake: Eat calcium-rich foods and take supplements if recommended by your doctor to support bone health.
  • Exercise regularly: Participate in weight-bearing and muscle-strengthening exercises, such as walking or light resistance training, to help maintain bone density.
  • Prevent falls: Keep your home free of trip hazards, use supportive footwear, and ensure good lighting to reduce the risk of fractures.
  • Avoid smoking and excessive alcohol: Smoking and heavy alcohol consumption can weaken bones and increase the risk of osteoporosis-related fractures.
     
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How Soon It Starts Working

The time required for Caldox Nasal Spray 30 MDI to start to work: The time required for Caldox Nasal Spray 30 MDI to show its action is unknown. The time for which the effects of Caldox Nasal Spray 30 MDI last: The duration of action for Caldox Nasal Spray 30 MDI is unknown.

What if you forget to take Caldox Nasal Spray 30 MDI

If you miss a dose, use it as soon as you remember on the same day. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not use two doses to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Caldox Nasal Spray 30 MDI out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Prime the spray correctly: Always prime a new bottle before its first use according to the product instructions.
  • Alternate nostrils: Use a different nostril with each daily dose to help minimise nasal irritation.
  • Keep the nozzle clean: Wipe the spray nozzle after each use and replace the protective cap.
  • Attend regular check-ups: Your doctor may examine your nasal passages periodically during long-term treatment.
  • Do not share your nasal spray: Sharing the bottle may spread infections.
     

verifiedApollotooltip
  • Lithium: Caldox Nasal Spray 30 MDI may reduce blood lithium concentrations, so your doctor may need to monitor lithium levels and adjust the dose if necessary.
  • Other osteoporosis medicines: Your doctor will decide whether Caldox Nasal Spray 30 MDI should be used together with other bone medications based on your individual treatment plan.
     

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verifiedApollotooltip

No clinically significant food interactions are known with Caldox Nasal Spray 30 MDI when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[HYPOCALCEMIC AGENTS]

FAQs

Caldox Nasal Spray 30 MDI is used to treat Postmenopausal osteoporosis.
Caldox Nasal Spray 30 MDI contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness).
If you have osteoporosis, avoid smoking, or try to quit. Tobacco use disrupts the mechanisms of bone turnover, resulting in reduced bone mass and bone mineral density (BMD), making bones prone to osteoporosis.
Caldox Nasal Spray 30 MDI contains Calcitonin, a hormone that regulates the calcium level in the blood. This hormone helps in bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damages bones become comparatively less; hence the bone damage is halted. Using Caldox Nasal Spray 30 MDI can increase bone formation by activation of the bone-forming cells.
Persons whose age is more than 45 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.
Yes, Caldox Nasal Spray 30 MDI is used together with calcium and vitamin D to treat bone loss in women with postmenopausal osteoporosis who have been postmenopausal for at least five years. Caldox Nasal Spray 30 MDI inhibits the function of osteoclasts (bone breakdown), reducing bone resorption; thus, combining calcium and calcitonin could result in a positive bone balance.
Store the unopened bottle in the refrigerator between 2°C- 8°C until ready to use, protect it from freezing. Caldox Nasal Spray 30 MDI in use can be stored at room temperature between 15°C- 30°C for 35 days in an upright position. Keep it out of reach from children.
Caldox Nasal Spray 30 MDI may increase the bone density. Caldox Nasal Spray 30 MDI helps reduce bone loss and damage in individuals with osteoporosis. In certain cases, it also promotes bone formation by stimulating bone-building cells, which can lead to increased bone density.
You are not recommended to use Caldox Nasal Spray 30 MDI if you are having any allergic reactions to calcitonin-salmon to avoid potential interactions. Therefore, please contact a doctor before using Caldox Nasal Spray 30 MDI. Do not self-medicate.
When using Caldox Nasal Spray 30 MDI, you are recommended to, inform your doctor if you have allergies to any of its active substances or a history of severe allergic reactions. Also, let them know if you are pregnant, planning to become pregnant, or breastfeeding. Calcitonin is not recommended for children. In rare cases, it may cause severe allergic reactions, such as bronchospasm, swelling of the tongue or throat, or anaphylactic shock. If any of these occur, seek immediate medical attention.
Caldox Nasal Spray 30 MDI causes side effects such as back pain, headache, muscle pain, and runny nose. However, these will gradually reduce over time and do not require any medical attention. Please, consult a doctor if persists longer.
Once you open a bottle of Caldox Nasal Spray 30 MDI, you can keep it at room temperature for up to 30 days. Be sure to keep the bottle stored in an upright position. Talk to your doctor or pharmacist if you are unsure about the safety of an opened bottle.
Yes, to get the maximum benefit for your bone health, you must use Caldox Nasal Spray 30 MDI exactly as your doctor has prescribed. Consistency is key to protecting your bones. Talk to your doctor if you find it hard to stay consistent.
Nasal congestion or a cold can interfere with how well your body absorbs the spray. If you have severe nasal symptoms, talk to your doctor or pharmacist to see if you should pause or adjust your treatment temporarily.
Alternating nostrils daily is important because it reduces the risk of local irritation, dryness, and nosebleeds in your nasal passages. Talk to your doctor if you experience persistent pain or discomfort in either nostril.
No, you should not use Caldox Nasal Spray 30 MDI if you have low blood calcium (hypocalcemia) because this medicine can lower calcium levels even more. Talk to your doctor to ensure your calcium levels are safe before starting this treatment.
Yes, most healthcare providers recommend taking daily calcium and Vitamin D supplements to ensure your body has the materials it needs to support bone strength while using Caldox Nasal Spray 30 MDI. Talk to your doctor to find out the specific supplement doses you need.
Caldox Nasal Spray 30 MDI is only approved for women who are at least five years past menopause and is not intended for use during pregnancy or breastfeeding. Talk to your doctor if you have questions about who this medicine is meant for.
If the pump becomes clogged, clean the outer nozzle carefully by rinsing it with warm water, but never insert a pin or sharp object into the nozzle, as this can ruin the mechanism. Talk to your pharmacist for step-by-step cleaning guidance.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

83/4 Friends Colony, Ballupur Distt, Dehradun, Uttarakhand 248001
Other Info - CAL3754
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