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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Caripriza 4.5 Capsule is used to treat psychotic disorders like schizophrenia. It also treats manic or mixed episodes in adults with bipolar disorder type I. It consists of Cariprazine, an atypical antipsychotic. It works by affecting the balance of the neurotransmitters in the brain. Thereby, It decreases psychotic symptoms like hallucinations and agitated behaviour associated with schizophrenia. It also treats depressive episodes in bipolar disorder type I/bipolar depression in adults.

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Whats That

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Composition :

CARIPRAZINE-4.5MG

Manufacturer/Marketer :

Mesmer Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Caripriza 4.5 Capsule

Caripriza 4.5 Capsule belongs to a group of medicines called 'antipsychotics,' primarily used to treat psychotic disorders like schizophrenia. It also treats manic or mixed episodes in adults with bipolar disorder type I.

Caripriza 4.5 Capsule consists of 'Cariprazine,' an atypical antipsychotic. It works by affecting the balance of the neurotransmitters in the brain. Thereby, Caripriza 4.5 Capsule decreases psychotic symptoms like hallucinations and agitated behaviour associated with schizophrenia. It also treats depressive episodes in bipolar disorder type I/bipolar depression in adults.

Your doctor will decide the dose and duration based on your medical condition and response to treatment. Common side effects include restlessness, tiredness, drowsiness, dizziness, tremors/shakiness, blurred vision, difficulty moving or slow movements, involuntary muscle movements, excess saliva/drooling, constipation, upset stomach, nausea, vomiting, increased appetite, and weight gain. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Caripriza 4.5 Capsule is not recommended for treatment in patients with dementia-related psychosis. Inform your doctor before starting Caripriza 4.5 Capsule if you have a history of liver/kidney/heart diseases, stroke, high blood pressure, diabetes, high cholesterol levels, swallowing problems, low white blood cell count, or fits. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before using Caripriza 4.5 Capsule . Avoid consuming alcohol while being treated with Caripriza 4.5 Capsule as it can make you dizzy or drowsy. Do not drive or operate machinery since this medicine can make you sleepy and interfere with your driving ability. The safety and efficacy of Cariprazine in children and adolescents under 18 years have not been established.

Uses of Caripriza 4.5 Capsule

Treatment of Schizophrenia and manic or mixed episodes in bipolar disorder type I

Directions for Use

• Caripriza 4.5 Capsule can be taken with or without food as advised by the doctor.• It is usually taken once in a day or as advised by the doctor.• Swallow Caripriza 4.5 Capsule as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Caripriza 4.5 Capsule is used to treat schizophrenia and associated psychotic symptoms. It contains Cariprazine, which affects the balance of the neurotransmitters in the brain. It helps in clear thinking and relieves psychotic symptoms like hallucinations in schizophrenia. It treats depressive episodes in bipolar disorder type I in adults. It is also an adjunctive therapy to antidepressants in treating major depressive disorder (MDD) in adults.

How Caripriza 4.5 Capsule Works

Caripriza 4.5 Capsule consists of 'Cariprazine,' an atypical antipsychotic. It works by affecting the balance of the neurotransmitters in the brain. Thereby, Caripriza 4.5 Capsule decreases psychotic symptoms like hallucinations and agitated behaviour associated with schizophrenia. It also treats depressive episodes in bipolar disorder type I/bipolar depression in adults.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Caripriza 4.5 Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Caripriza 4.5 Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Caripriza 4.5 Capsule may include fatigue, irregular heartbeat, and orthostatic hypotension. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Caripriza 4.5 Capsule is not recommended for treatment in elderly patients with dementia-related psychosis. Before using Caripriza 4.5 Capsule , let your doctor know if you have a history of liver or kidney diseases, heart problems, stroke, high blood pressure, diabetes, high cholesterol levels, swallowing problems, low white blood cell count, obesity, dehydration, or fits. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother before starting Caripriza 4.5 Capsule . Avoid consuming alcohol during the treatment, as it might increase dizziness and drowsiness. Avoid driving or operating machinery, as this medicine may decrease your mental alertness, making you feel dizzy or drowsy. Caripriza 4.5 Capsule is not recommended for patients below 18 years of age as safety and effectiveness have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Caripriza 4.5 Capsule:
Co-administration of Metoclopramide with Caripriza 4.5 Capsule can increase the risk of side effects.

How to manage the interaction:
Taking Caripriza 4.5 Capsule with Metoclopramide is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Caripriza 4.5 Capsule:
When buprenorphine is used with Caripriza 4.5 Capsule, it may possibly lead to side effects.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Caripriza 4.5 Capsule can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop any medication without consulting a doctor. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Caripriza 4.5 Capsule:
When Caripriza 4.5 Capsule is taken with Modafinil, it reduces the blood levels of Caripriza 4.5 Capsule which may make the medication less effective.

How to manage the interaction:
Co-administration of Modafinil with Caripriza 4.5 Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CariprazineSaquinavir
Severe
How does the drug interact with Caripriza 4.5 Capsule:
Taking Caripriza 4.5 Capsule and Saquinavir can significantly increase the blood levels of Caripriza 4.5 Capsule that may increase the risk of severe side effects.

How to manage the interaction:
Although taking Caripriza 4.5 Capsule with Saquinavir can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, weight gain, difficulty swallowing or having seizures, it's important to let your doctor know. Do not stop using any medications without a doctor's advice.
How does the drug interact with Caripriza 4.5 Capsule:
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with Caripriza 4.5 Capsule.

How to manage the interaction:
Although taking Caripriza 4.5 Capsule and Topiramate together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like not sweating enough, having a high body temperature, or feeling tired, dizzy, or lightheaded, it's important to contact a doctor. Do not stop using any medications without a doctor's advice.
CariprazineEnzalutamide
Severe
How does the drug interact with Caripriza 4.5 Capsule:
When Caripriza 4.5 Capsule is taken with Enzalutamide, it reduces the blood levels of Caripriza 4.5 Capsule which may make the medication less effective.

How to manage the interaction:
Although taking Caripriza 4.5 Capsule and Enzalutamide together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any unusual symptoms or if your condition worsens, make sure to contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Caripriza 4.5 Capsule:
When Caripriza 4.5 Capsule is taken with Lorlatinib, it may reduce the blood levels of Caripriza 4.5 Capsule.

How to manage the interaction:
Although taking Caripriza 4.5 Capsule and Lorlatinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any unusual symptoms or if your condition worsens, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Caripriza 4.5 Capsule:
Taking Caripriza 4.5 Capsule with Bosentan may reduce the blood levels of Caripriza 4.5 Capsule, which may make the medication less effective.

How to manage the interaction:
Taking Bosentan with Caripriza 4.5 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Caripriza 4.5 Capsule:
Taking Caripriza 4.5 Capsule with clarithromycin can significantly increase the blood levels of Caripriza 4.5 Capsule.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Caripriza 4.5 Capsule if prescribed by the doctor. However, consult the doctor if you experience dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations. Do not discontinue the medication without consulting a doctor.
CariprazineIdelalisib
Severe
How does the drug interact with Caripriza 4.5 Capsule:
Taking Caripriza 4.5 Capsule and Idelalisib can significantly increase the blood levels of Caripriza 4.5 Capsule.

How to manage the interaction:
Although taking Caripriza 4.5 Capsule and Idelalisib together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations, it's important to let a doctor know. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps reduce cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps improve overall health and possibly protects the brain.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid alcohol consumption while using Caripriza 4.5 Capsule . Alcohol intake while being treated with Caripriza 4.5 Capsule , may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Using antipsychotic drugs during the third trimester of pregnancy may cause extrapyramidal (drug-induced movement disorders) and/or withdrawal symptoms in newborn babies. Please consult your doctor before taking Caripriza 4.5 Capsule if you are pregnant or planning to conceive. Your doctor will weigh the potential risks and benefits before prescribing Caripriza 4.5 Capsule .

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Breast Feeding

Caution

It is not known if Cariprazine is excreted into breast milk. Please consult your doctor before taking Caripriza 4.5 Capsule if you are a breastfeeding mother.

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Driving

Unsafe

Caripriza 4.5 Capsule may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed with Caripriza 4.5 Capsule .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases when you are prescribed with Caripriza 4.5 Capsule .

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Children

Unsafe

Caripriza 4.5 Capsule is not recommended for use in children and adolescents below 18 years of age as safety and effectiveness have not been established.

Have a query?

FAQs

Caripriza 4.5 Capsule is used to treat schizophrenia and manic or mixed episodes in bipolar disorder type I.

Caripriza 4.5 Capsule contains Cariprazine, an antipsychotic that affects the balance of neurotransmitters in the brain, thus improving mood, behaviour, and thoughts in schizophrenia.

Caripriza 4.5 Capsule may make you sweat less and can likely cause a heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.

Caripriza 4.5 Capsule can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Caripriza 4.5 Capsule are advised to monitor their blood pressure levels regularly to avoid such unpleasant events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.

Country of origin

India

Manufacturer/Marketer address

No. 202/6, Lane No. 30, Phase- Ii, Ida, Cherlapally, Hyderabad-500051, Telangana, India
Other Info - CAR1677

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