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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Caspoeva 70 Injection is used to treat fungal infections. It contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

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Composition :

CASPOFUNGIN-70MG

Manufacturer/Marketer :

CONCORD DRUGS LTD

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Caspoeva 70 Injection

Caspoeva 70 Injection belongs to the class of medicines known as 'antifungals' used to treat various fungal infections. A fungal infection is caused when a fungus invades and affects any body part.

Caspoeva 70 Injection contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

A qualified healthcare professional will administer Caspoeva 70 Injection. In some cases, you may experience certain common side effects, such as injection site reactions, headaches, dizziness, nausea, vomiting, diarrhoea, stomach pain, tremors, sweating, high blood pressure, difficulty sleeping and swelling of the hands, ankles, or feet. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Caspoeva 70 Injection, inform your doctor about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use any other medicines with Caspoeva 70 Injection without a doctor's recommendation. Caspoeva 70 Injection may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of alcohol while on Caspofungin therapy.

Uses of Caspoeva 70 Injection

Caspoeva 70 Injection is used to treat serious fungal infections. The detailed uses of Caspoeva 70 Injection are as follows:<br/>• Treats invasive candidiasis: Caspoeva 70 Injection is used for yeast infections in the blood, stomach, lungs, and oesophagus.<br/>• Manages certain resistant fungal infections: Caspoeva 70 Injection is given when other antifungal treatments have failed or are not suitable.<br/>• Used in immunocompromised patients: Caspoeva 70 Injection helps treat serious fungal infections in people with weakened immune systems.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Caspoeva 70 Injection will be administered in the hospital by a trained healthcare professional.• Do not self-administer.

Medicinal Benefits

Caspoeva 70 Injection is an antifungal agent, a medicine used to treat several fungal infections. It can be used to treat fungal infections that other drugs have failed to treat. It is also used to treat serious fungal infections in persons who have a reduced immune system. Caspoeva 70 Injection works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its membrane formation. As a result, fungal cells get killed, or their growth is minimized.

How Caspoeva 70 Injection Works

Caspoeva 70 Injection contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

Storage

• Store in a cool and dry place away from sunlight.• Keep Caspoeva 70 Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Caspoeva 70 Injection
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Eat foods rich in vitamin C, beta-carotene, and antioxidants, such as citrus fruits, orange vegetables, and berries.
  • Include healthy fats like fatty fish, avocados, and nuts in your diet.
  • Drink plenty of water and limit sun exposure to maintain skin hydration and protect against damage.
  • Practice stress management and relaxation techniques like deep breathing exercises, progressive muscle relaxation, and meditation.
  • Limit or avoid processed foods, sugary drinks, and excessive alcohol to prevent premature aging.
  • Consult a dermatologist if you experience significant changes in skin colour.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

What if I have taken an overdose of Caspoeva 70 Injection

Caspoeva 70 Injection is administered in a hospital setting under the supervision of your doctor or medical personnel. Thus, an overdose is quite improbable. While in the hospital, you will be constantly monitored to ensure that any unpleasant side effects are handled.

Drug Warnings

It is recommended not to use Caspoeva 70 Injection if you are allergic to any component present, so inform your doctor about your sensitivities with medicines and foods. Also, let your doctor know about your medical condition and the medications you are currently using. Do not use any other drugs with Caspoeva 70 Injection without a doctor’s recommendation. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

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CaspofunginFosphenytoin
Severe

Drug-Drug Interactions

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How does the drug interact with Caspoeva 70 Injection:
Leflunomide can cause liver problems, and combining it with other drugs, such as binimetinib, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Caspoeva 70 Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, dark urine, stomach pain, unusual bleeding or bruising, feeling tired, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
CaspofunginFosphenytoin
Severe
How does the drug interact with Caspoeva 70 Injection:
Coadministration of Caspoeva 70 Injection and Fosphenytoin can reduce the levels of Caspoeva 70 Injection in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Caspoeva 70 Injection and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Caspoeva 70 Injection:
Coadministration of Phenytoin and Caspoeva 70 Injection may decrease the blood levels of Caspoeva 70 Injection, which may make Caspoeva 70 Injection less effective.

How to manage the interaction:
Although taking Phenytoin and Caspoeva 70 Injection together can result in an interaction, it can be taken if your doctor has prescribed it. If your infection gets worse or if your symptoms don't go away, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Caspoeva 70 Injection:
Coadministration of ketoconazole with Caspoeva 70 Injection may raise the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Caspoeva 70 Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Caspoeva 70 Injection:
Co-administration of Dexamethasone with Caspoeva 70 Injection may cause Caspoeva 70 Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Caspoeva 70 Injection and Dexamethasone, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Caspoeva 70 Injection:
Taking carbamazepine and Caspoeva 70 Injection together may result in decreasing the effects of Caspoeva 70 Injection.

How to manage the interaction:
Although taking carbamazepine and Caspoeva 70 Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Caspoeva 70 Injection:
Taking Caspoeva 70 Injection and Efavirenz together reduces the levels and effectiveness of Caspoeva 70 Injection.

How to manage the interaction:
Although taking Caspoeva 70 Injection and Efavirenz together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Caspoeva 70 Injection:
Using nevirapine together with Caspoeva 70 Injection may cause Caspoeva 70 Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Caspoeva 70 Injection and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Caspoeva 70 Injection:
Taking Rifampicin in combination with Caspoeva 70 Injection may make Caspoeva 70 Injection less effective.

How to manage the interaction:
There may be a possibility of interaction between Caspoeva 70 Injection and Rifampicin, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very high sugar or high-carbohydrate diet may increase the count of Candida in some people.
  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of any disease.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS
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Alcohol

Caution

Avoiding alcohol is recommended to rule out any possibility of side effects.

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Pregnancy

Caution

Caspoeva 70 Injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if Caspoeva 70 Injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Caspoeva 70 Injection.

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Driving

Caution

Caspoeva 70 Injection may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

Inform your doctor before receiving the Caspoeva 70 Injection if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Caspoeva 70 Injection if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Please consult your doctor. Your doctor may prescribe this medicine if the benefits outweigh the risks.

Have a query?

FAQs

Caspoeva 70 Injection is used to treat Fungal infections.

Caspoeva 70 Injection contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow.

Caspoeva 70 Injection is not suitable for patients with known hypersensitivity to any components present in Caspoeva 70 Injection.

Caspoeva 70 Injection is unlikely to interfere with your contraception, including the combination pill or emergency contraception. For further information, seek medical advice from your healthcare professional.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, avoiding close direct contact until the infection is clear and avoiding sharing things with the infected person is recommended, as it can also spread the infection.

No, you can continue to eat and drink normally while taking Caspoeva 70 Injection unless instructed by the doctor.

No, Caspoeva 70 Injection is not an antibiotic. It belongs to the class of medicines called antifungals.

Caspoeva 70 Injection is administered as a slow intravenous injection, usually once a day, by a qualified healthcare professional. The injection is given over about one hour. The dosage and treatment duration will be determined by your doctor based on your specific condition. Do not self-administer.

Caspoeva 70 Injection targets fungal infections. It works by inhibiting the growth of the fungi, helping to treat conditions like candidemia (bloodstream infection) and invasive aspergillosis (serious infection by aspergillus fungus, in the lungs).

Caspoeva 70 Injection is effective when used as per the dosage and duration recommended by a doctor. Do not self-medicate.

Caspoeva 70 Injection causes side effects such as injection site reactions, headache, dizziness, chills, nausea, vomiting, diarrhoea, stomach pain tremor, high blood pressure, swelling of hands, ankles, or feet and difficulty sleeping. Please, consult a doctor if these persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

3-2-342 & 343, 2Nd Floor, Chappal Bazar, Kachiguda, Hyderabad, Telangana 500027
Other Info - CAS0155

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