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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Celtranz 500mg Injection 5 ml is used to treat Abnormal heavy bleeding. It contains an anti-fibrinolytic drug, tranexamic acid, which helps the body's natural blood clotting system by reducing fibrin breakdown and inhibiting fibrinolysis, a process that limits the development of blood clots. As a result, it contributes to the prevention of excessive bleeding. Common side effects of Celtranz 500mg Injection 5 ml include feeling sick (nausea), diarrhoea, vomiting, itchy skin, and pain at the injection site.
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Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Celtranz 500mg Injection 5 ml

Celtranz 500mg Injection 5 ml belongs to the class of medications called ‘anti-fibrinolytic drugs. It is mainly used to treat abnormal bleeding in various conditions such as menorrhagia (heavy bleeding in periods), epistaxis (nose bleeds), cervical surgery (conization of the cervix), post-prostatectomy (prostate surgery), post-cystectomy (bladder surgery), traumatic hyphaema (bleeding inside the eye), before tooth removal (dental extraction) in hemophiliacs (people who bleed more easily than normal) and a hereditary disease called angioneurotic oedema (HANO).

Celtranz 500mg Injection 5 ml contains an anti-fibrinolytic drug, tranexamic acid. Tranexamic acid helps the body's natural blood clotting system by reducing fibrin breakdown, which inhibits fibrinolysis, a process that limits the development of blood clots. As a result, Celtranz 500mg Injection 5 ml contributes to the prevention of excessive bleeding.

Celtranz 500mg Injection 5 ml is a parenteral form. It will be administered by the healthcare professional; do not self-administer. Celtranz 500mg Injection 5 ml may cause side effects such as feeling sick (nausea), diarrhoea, vomiting, itchy skin, and pain at the injection site. These side effects usually disappear with time. However, consult your doctor immediately if these side effects persist or if you develop any other serious side effects, such as vision problems while using Celtranz 500mg Injection 5 ml.

If you are allergic to Celtranz 500mg Injection 5 ml or any other medicines, please inform your doctor. Inform your doctor if you have pre-existing or a history of kidney disease, disseminated intravascular coagulation (a disease where blood clots form throughout your body), thrombosis (formation of blood clots in the blood vessels) or seizures (fits), as this medicine is not recommended in such cases. Also, inform your doctor before receiving this injection if you are using any birth control pills or fibrinolytic agents (medicines that dissolve blood clots) or if you are pregnant, planning pregnancy or breastfeeding.

Uses of Celtranz 500mg Injection 5 ml

Treatment of Abnormal heavy bleeding

Directions for Use

A healthcare professional will administer the injection, so do not self-administer.

Medicinal Benefits

Celtranz 500mg Injection 5 ml contains tranexamic acid, which is an anti-fibrinolytic medication. Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, and this stops fibrinolysis, a process that stops blood clot formation. Thus Celtranz 500mg Injection 5 ml helps to prevent excessive bleeding.

How Celtranz 500mg Injection 5 ml Works

Celtranz 500mg Injection 5 ml contains an anti-fibrinolytic drug, tranexamic acid. Tranexamic acid helps the body's natural blood clotting system by reducing fibrin breakdown, which inhibits fibrinolysis, a process that limits the development of blood clots. As a result, Celtranz 500mg Injection 5 ml contributes to the prevention of excessive bleeding.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Celtranz 500mg Injection 5 ml

  • Nausea
  • Diarrhoea
  • Itchy skin
  • Pain at the injection site
  • Injection site reactions
  • Vomiting

What if I have taken an overdose of Celtranz 500mg Injection 5 ml

As Celtranz 500mg Injection 5 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Celtranz 500mg Injection 5 ml may cause severe gastrointestinal symptoms, hypotension, thromboembolism, visual impairment, convulsions, mental status changes, and rash.

Drug Warnings

Before administering Celtranz 500mg Injection 5 ml, inform your doctor if you notice blood in your urine (except during periods), or have a history of uncontrollable bleeding, disseminated intravascular coagulation (DIC) (a disease where blood clots form throughout your body), irregular periods and kidney disease. Also, inform your doctor if you or your family has a history of thrombosis (formation of blood clots in the blood vessels). Let your doctor know if you are taking medicine to treat a hereditary disease called angioneurotic oedema (HANO) every day for a long time. Your doctor may advise regular eye tests and blood tests to check your vision problems and also liver/kidney functioning. Inform your doctor if you are using birth control pills, including the patch, vaginal ring, and an intrauterine device (IUD), as there is a risk of deep vein thrombosis (a condition in which a blood clot is formed in the deeper vein, mostly the legs). Inform your doctor if you are using fibrinolytic agents (drugs that break blood clots) such as streptokinase, as they may stop the effect of Celtranz 500mg Injection 5 ml. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding.

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
Tranexamic acidEthinylestradiol
Critical

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
How does the drug interact with Celtranz 500mg Injection 5 ml:
Taking drospirenone with Celtranz 500mg Injection 5 ml may increase the risk of blood clot formation.

How to manage the interaction:
Taking Celtranz 500mg Injection 5 ml with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidEthinylestradiol
Critical
How does the drug interact with Celtranz 500mg Injection 5 ml:
Taking Ethinylestradiol with Celtranz 500mg Injection 5 ml may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Celtranz 500mg Injection 5 ml is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidLevonorgestrel
Critical
How does the drug interact with Celtranz 500mg Injection 5 ml:
Taking Levonorgestrel with Celtranz 500mg Injection 5 ml may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Celtranz 500mg Injection 5 ml with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidEtonogestrel
Critical
How does the drug interact with Celtranz 500mg Injection 5 ml:
Co-administration of Celtranz 500mg Injection 5 ml may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Celtranz 500mg Injection 5 ml with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidMedroxyprogesterone
Critical
How does the drug interact with Celtranz 500mg Injection 5 ml:
Taking Medroxyprogesterone acetate with Celtranz 500mg Injection 5 ml may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Celtranz 500mg Injection 5 ml is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
Tranexamic acidChlorotrianisene
Severe
How does the drug interact with Celtranz 500mg Injection 5 ml:
Co-administration of Chlorotrianisene with Celtranz 500mg Injection 5 ml can increase the risk of blood clots.

How to manage the interaction:
Taking chlorotrianisene with Celtranz 500mg Injection 5 ml is not recommended due to its increased effects, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidTretinoin
Severe
How does the drug interact with Celtranz 500mg Injection 5 ml:
Co-administration of tretinoin with Celtranz 500mg Injection 5 ml may increase the risk of blood clots.

How to manage the interaction:
Taking tretinoin with Celtranz 500mg Injection 5 ml is not recommended due to its increased effects, however, it can be taken only if your doctor has advised it. If you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidEstradiol
Severe
How does the drug interact with Celtranz 500mg Injection 5 ml:
Co-administration of Estradiol with Celtranz 500mg Injection 5 ml can increase the risk of blood clots.

How to manage the interaction:
Taking Estradiol with Celtranz 500mg Injection 5 ml can lead to an interaction; however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidCarfilzomib
Severe
How does the drug interact with Celtranz 500mg Injection 5 ml:
Co-administration of Carfilzomib with Celtranz 500mg Injection 5 ml can increase the risk of blood clots.

How to manage the interaction:
Taking carfilzomib with Celtranz 500mg Injection 5 ml is not recommended due to its increased effects, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidEstrone
Severe
How does the drug interact with Celtranz 500mg Injection 5 ml:
Co-administration of Estrone with Celtranz 500mg Injection 5 ml can increase the risk of blood clots.

How to manage the interaction:
Taking Estrone with Celtranz 500mg Injection 5 ml can possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.
  • Stay hydrated; drink plenty of water.
  • Cut down on sugars, salts, spicy food, coffee, and alcohol.
  • A heating pad can help ease the pain by placing it on the belly or lower back.
  • Exercise can help ease the pain of menstrual cramps.
  • Avoid stress by performing meditation or yoga.
  • Massage your lower back or abdomen to relieve the pain.
  • Take proper rest.

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Celtranz 500mg Injection 5 ml Substitute

Substitutes safety advice
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  • Tyrodin-FSR Tablet 10's

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    16.65per tablet
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Alcohol

Caution

Celtranz 500mg Injection 5 ml may not interact with alcohol. However, avoid the consumption of alcohol as it may worsen your health condition.

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Pregnancy

Caution

Celtranz 500mg Injection 5 ml should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Celtranz 500mg Injection 5 ml.

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Breast Feeding

Caution

Celtranz 500mg Injection 5 ml should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Celtranz 500mg Injection 5 ml.

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Driving

Caution

Celtranz 500mg Injection 5 ml does not affect your ability to drive or operate machinery. However, do not drive if you experience unwanted effects after taking Celtranz 500mg Injection 5 ml.

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Liver

Caution

No information is available on the use of Celtranz 500mg Injection 5 ml in patients with liver problems. Inform your doctor if you have liver conditions. Your doctor may adjust the dose or prescribe a suitable alternative if needed based on your health condition.

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Kidney

Caution

Celtranz 500mg Injection 5 ml should be used with caution in patients with kidney diseases. Inform your doctor if you have kidney conditions. Your doctor may adjust the dose or prescribe a suitable alternative if needed based on your health condition.

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Children

Caution

Celtranz 500mg Injection 5 ml should be used in children below 12 years of age only if clinically needed. The dose will be decided by your doctor based on your child's age and condition.

FAQs

Celtranz 500mg Injection 5 ml is used to treat abnormal or unwanted bleeding.

Celtranz 500mg Injection 5 ml contains tranexamic acid, an anti-fibrinolytic drug. Tranexamic acid helps the body's natural blood clotting mechanism by reducing fibrin breakdown, which prevents fibrinolysis, a process that prevents blood clot formation. As a result, Celtranz 500mg Injection 5 ml helps to prevent excessive bleeding.

Taking this medication together with birth control pills may raise your chance of getting blood clots. To avoid pregnancy, use another method of birth control (such as condoms or spermicide). Consult your doctor in case of concerns.

People who have frequent nosebleeds or heavy periods can take tranexamic acid for a long time, for months or years. They normally only take it for a few days or a week at a time when the bleeding is severe. Take this medicine as your doctor prescribed.

Appropriate investigations have not revealed any geriatric-specific issues that would restrict the use of Celtranz 500mg Injection 5 ml in the elderly. However, senior people are more prone to develop age-related renal issues. Thus, patients getting this medication should exercise caution.

Country of origin

INDIA

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - CEL0127

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