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compositionComposition:CHLORTHALIDONE-12.5MG
prescription
Prescription Medicine
info
Chlohat 12.5mg Tablet
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORTHALIDONE-12.5MG

Manufacturer/Marketer :

Akesiss Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Chlohat 12.5mg Tablet

Chlohat 12.5mg Tablet is a prescription medicine used to treat high blood pressure and reduce swelling caused by excess fluid in your body. By helping your kidneys remove extra salt and water, this medication decreases the workload on your heart and blood vessels. Using it consistently helps protect your long-term health by reducing the risk of strokes and heart attacks.

For the best results, you should take Chlohat 12.5mg Tablet at the same time every day, preferably in the morning to prevent having to wake up during the night to urinate. You can take this medicine with or without food, but maintaining a consistent routine is important for steady blood pressure control. Combining this treatment with a low-salt diet and regular, doctor-approved exercise will help you achieve the best possible results.

While taking this medicine, you may experience mild side effects like an increased need to urinate, mild dizziness, or a temporary headache. These symptoms are usually manageable, but you must contact your doctor immediately if you experience serious side effects such as severe muscle cramps, extreme thirst, or an irregular heartbeat.

Before you begin taking Chlohat 12.5mg Tablet, talk to your doctor if you have a history of kidney disease, liver damage, diabetes, gout, or low potassium levels. Do not take this if you are unable to pass urine or if you have a known severe allergy to sulfonamide medications.

Certain medicines, including regular pain relievers and other blood pressure drugs, can interact with Chlohat 12.5mg Tablet and affect how it works. Drinking alcohol while taking this medicine can cause your blood pressure to drop too low, leading to severe dizziness. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist before starting this treatment to ensure it is safe for you.

Uses of Chlohat 12.5mg Tablet

Chlohat 12.5mg Tablet contains chlorthalidone and is used to lower blood pressure and reduce excess fluid accumulation in the body. The detailed uses of Chlohat 12.5mg Tablet are as follows: 

  • High Blood Pressure (Hypertension): Chlohat 12.5mg Tablet helps lower elevated blood pressure, which reduces the workload on your heart and protects your blood vessels from long-term damage.
  • Fluid Retention (Oedema): Chlohat 12.5mg Tablet helps your body eliminate excess water and salt caused by conditions like heart failure, kidney disease, or liver disease, reducing swelling in your limbs.

Key Benefits

Chlohat 12.5mg Tablet helps control blood pressure and reduce excess fluid in the body, supporting cardiovascular health and improving physical comfort.  Regular treatment helps protect against the complications associated with uncontrolled high blood pressure.

  • Long-Lasting Blood Pressure Control: Chlohat 12.5mg Tablet provides sustained blood pressure control throughout the day and night, helping reduce the risk of serious cardiovascular events such as strokes and heart attacks.
  • Relief from Swelling and Fluid Retention: By helping remove excess fluid from the body, Chlohat 12.5mg Tablet reduces swelling in the legs, ankles, and feet, making walking, movement, and other daily activities more comfortable.
Side effects of Chlohat 12.5mg Tablet
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Quit smoking as smoking impairs erectile function by significantly damaging blood vessels.
  • Maintain a healthy weight as overweight can cause erectile dysfunction.
  • Exercise regularly as physical activity enhances blood flow and overall health, benefiting erectile function.
  • Consume a healthy diet loaded with whole grains, fruits and vegetables.
  • Limit alcohol consumption as excessive alcohol intake can impair erectile function.
  • Manage stress by practicing techniques such as yoga, relaxation exercises or meditation.
  • In case erectile dysfunction is due to psychological factors, consider couple counselling or sex therapy to address relationship and anxiety issues.
  • Openly discuss your concerns with your partner.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.

Directions for Use

Follow these step-by-step instructions to take your medicine safely:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • Take this medicine in the morning to prevent nighttime sleep disruptions from needing to urinate.
  • You can take your dose with or without food, but try to do it the same way every day.

Always follow your doctor's exact instructions regarding your treatment. Do not stop taking this medication suddenly, even if you feel completely well.

How Chlohat 12.5mg Tablet Works

Chlohat 12.5mg Tablet contains chlorthalidone, which belongs to a group of medicines known as diuretics, commonly called 'water pills.' It acts directly on the filtering units of your kidneys to increase the amount of sodium and water that your body removes from your bloodstream and excretes through your urine. As your body sheds this extra salt and water, the total volume of blood circulating through your blood vessels goes down. This reduction in fluid volume lowers the pressure against your artery walls and decreases the strain on your heart, allowing it to pump blood more easily throughout your body.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Chlohat 12.5mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Chlohat 12.5mg Tablet is classified as FDA pregnancy risk category B. So, Chlohat 12.5mg Tablet should not be used during pregnancy unless clearly necessary. Prolonged intake of Chlohat 12.5mg Tablet during pregnancy may cause jaundice (yellowing of skin and eye), unexplained bruising, low blood sugar and electrolyte imbalance in the neonates (newborn baby). Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

Chlohat 12.5mg Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please talk to your doctor.

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Driving

Unsafe

Driving after taking Chlohat 12.5mg Tablet is not recommended as it may occasionally cause drowsiness.

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Liver

Caution

Chlohat 12.5mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Chlohat 12.5mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Caution

Chlohat 12.5mg Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

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Heart

Safe if prescribed

Chlohat 12.5mg Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Chlohat 12.5mg Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Chlohat 12.5mg Tablet

Do not take more than the prescribed dose of Chlohat 12.5mg Tablet as it may cause serious side effects. The symptoms of overdose include drowsiness, dizziness, nausea, weakness, muscle pain, extreme thirst, or rapid heartbeats. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Monitor your sodium intake: Reduce the amount of salt in your meals and avoid processed foods, as excess sodium can prevent Chlohat 12.5mg Tablet from working effectively.
  • Eat potassium-rich foods: Since this medicine can cause your body to lose potassium, include foods like bananas, oranges, spinach, and sweet potatoes in your diet if recommended by your doctor.
  • Stay safely hydrated: Ask your doctor how much fluid you should drink each day, as getting dehydrated can increase the risk of dizziness and kidney strain.
  • Limit alcohol consumption: Avoid or strictly limit alcohol, as it can combine with your medicine to cause a sudden, severe drop in blood pressure.
  • Track your blood pressure: Keep a daily log of your blood pressure readings at home to share with your doctor during your routine check-ups.

Have a query?

How Soon It Starts Working

  • The time required for Chlohat 12.5mg Tablet to start to work: The time required for Chlohat 12.5mg Tablet to start to work is 3 hours after administration.
  • The time for which the effects of Chlohat 12.5mg Tablet last: The effect of Chlohat 12.5mg Tablet lasts for 24 hours.

What if you forget to take Chlohat 12.5mg Tablet

If you miss a dose of Chlohat 12.5mg Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Chlohat 12.5mg Tablet tablets at room temperature, ideally between 68°F and 77°F (20°C and 25°C). • Keep the medication inside its original container, tightly closed, to protect it from moisture and direct light. Do not store this medicine in your bathroom

Drug Warnings

  • Stand Up Slowly: Stand up slowly from a sitting or lying position to help reduce the risk of dizziness, lightheadedness, and fainting.
  • Protect Your Skin from Sunlight: Avoid excessive exposure to direct sunlight, as this medicine may increase your sensitivity to sunburn. Wear protective clothing and apply sunscreen when outdoors.
  • Attend Regular Blood Tests: Keep all scheduled blood test appointments so your doctor can monitor your kidney function and electrolyte levels regularly.
  • Monitor Blood Sugar Levels: If you have diabetes, check your blood sugar levels closely, as this medicine may occasionally cause blood sugar levels to increase.
  • Inform Healthcare Providers Before Procedures: Tell your dentist, surgeon, or other healthcare providers that you are taking Chlohat 12.5mg Tablet before undergoing any medical or dental procedures.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Chlohat 12.5mg Tablet: 

  • Lithium: Taking Chlohat 12.5mg Tablet can reduce how quickly your body clears lithium, raising it to dangerous, toxic levels in your bloodstream.
  • NSAIDs (like ibuprofen or naproxen): These common pain relievers can reduce the effectiveness of Chlohat 12.5mg Tablet and increase your risk of kidney damage.
  • Other blood pressure medications: Combining this medicine with other drugs that lower blood pressure can increase the risk of your blood pressure dropping too low.
  • Digoxin: Low potassium levels caused by Chlohat 12.5mg Tablet can increase your risk of developing serious, toxic side effects from digoxin.


Drug-Food Interactions

Certain foods, beverages, and dietary products may affect how Chlohat 12.5mg Tablet works or increase the risk of side effects. Examples include: 

  • Natural Liquorice: Eating natural liquorice can worsen potassium loss when combined with this medication.


Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Chlohat 12.5mg Tablet, as additional monitoring or treatment adjustments may be required: 

  • Anuria (Inability to urinate): Do not take this medicine if you are unable to pass urine, as it relies on active kidney function to work.
  • Gout: This medicine can raise uric acid levels in your blood, which may trigger or worsen painful gout attacks.
  • Diabetes: Chlohat 12.5mg Tablet can affect your blood sugar control, which may require your doctor to adjust your diabetes medications.
chlorthalidoneCisapride
Critical
chlorthalidoneAminolevulinic acid
Severe

Drug-Drug Interactions

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chlorthalidoneCisapride
Critical
How does the drug interact with Chlohat 12.5mg Tablet:
Co-administration of Chlohat 12.5mg Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Chlohat 12.5mg Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
chlorthalidoneAminolevulinic acid
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Co-administration of Aminolevulinic acid and Chlohat 12.5mg Tablet may increase the risk of severe sunburn.

How to manage the interaction:
Taking Chlohat 12.5mg Tablet with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact your doctor right away. Do not discontinue any medications without consulting a doctor.
chlorthalidoneDroperidol
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Taking Droperidol can make Chlohat 12.5mg Tablet less effective in lowering blood pressure.

How to manage the interaction:
Taking Chlohat 12.5mg Tablet with Droperidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include an irregular heart rhythm, severe or long-lasting diarrhea or vomiting, complications, sudden dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, and feeling nauseous or vomiting. Do not stop using any medications without first talking to your doctor.
chlorthalidoneAmiodarone
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Coadministration of Chlohat 12.5mg Tablet with amiodarone may increase the risk of abnormal heart rhythms.

How to manage the interaction:
Although taking Chlohat 12.5mg Tablet with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.
chlorthalidoneTizanidine
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Co-administration of Tizanidine and Chlohat 12.5mg Tablet may show additive effects and increase the risk of low blood pressure.

How to manage the interaction:
Although there is an interaction, Chlohat 12.5mg Tablet can be taken with tizanidine if prescribed by the doctor. If you experience headache, dizziness, palpitations, or sweating, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
chlorthalidoneZiprasidone
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Co-administration of Chlohat 12.5mg Tablet with ziprasidone can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction, Chlohat 12.5mg Tablet can be taken with ziprasidone if prescribed by the doctor. but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
chlorthalidonePimozide
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Co-administration of Chlohat 12.5mg Tablet with pimozide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction, Chlohat 12.5mg Tablet can be taken with pimozide if prescribed by the doctor. Consult the prescriber if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with pimozide. Also, let the doctor know if you experience signs of electrolyte disturbance, such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
chlorthalidoneArsenic trioxide
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Taking Chlohat 12.5mg Tablet can make the body eliminate Arsenic trioxide faster, leading to lower levels in the blood and potentially reducing its effectiveness.

How to manage the interaction:
Co-administration of Chlohat 12.5mg Tablet with Arsenic trioxide can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: your heart beating irregularly, feeling dizzy or lightheaded, fainting, having a fast or pounding heartbeat, feeling weak or drowsy, being confused, experiencing muscle pain, or feeling nauseous or vomiting. Do not discontinue any medications without consulting a doctor.
chlorthalidoneLithium
Severe
How does the drug interact with Chlohat 12.5mg Tablet:
Co-administration of Chlohat 12.5mg Tablet together with lithium can increase the effects of lithium.

How to manage the interaction:
Although there is a interaction between Chlohat 12.5mg Tablet and lithium, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience diarrhea, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Chlohat 12.5mg Tablet is used to treat high blood pressure (hypertension) and oedema (a build-up of fluid in the body).

Chlohat 12.5mg Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This, in turn, reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. So, it helps to lower high blood pressure, reducing the chances of a heart attack or stroke.

Taking Chlohat 12.5mg Tablet may cause dehydration. So, to avoid dehydration, drink plenty of fluids and inform your doctor if you feel extremely thirsty.

It is unlikely that Chlohat 12.5mg Tablet affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There is not enough evidence to say for certain. For the best advice, consult your doctor.

Chlohat 12.5mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are lifelong conditions and one should not abruptly discontinue them without discussing it with a doctor.

Yes, Chlohat 12.5mg Tablet is a diuretic (water pill), which increasing the amount of urine that is passed out from the kidneys.

Take Chlohat 12.5mg Tablet as prescribed by the doctor. It can be taken daily if advised by the doctor.

You are recommended not to consume alcohol along with Chlohat 12.5mg Tablet to avoid unpleasant side-effects.

Taking more than the recommended dose of Chlohat 12.5mg Tablet may cause serious side effects. The symptoms of overdose include drowsiness, dizziness, nausea, weakness, muscle pain, extreme thirst, or rapid heartbeats. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately. Avoid exceeding the recommended dose and take Chlohat 12.5mg Tablet as advised by the doctor.

Consult the doctor before taking ibuprofen with Chlohat 12.5mg Tablet as dose adjustment may be needed to safely take both the medicines together.

Yes, Chlohat 12.5mg Tablet may increase uric acid levels leading to gout. Inform the doctor if you have gout or if you notice symptoms of gout such as sudden/severe attack of pain, swelling, redness and tenderness in one or more joints.

Chlohat 12.5mg Tablet may not cause skin cancer. However, it might cause sensitivity to sunlight. Wear protective clothing and use sunscreen while going out.

Chlohat 12.5mg Tablet may cause side effects like headaches, nausea or dizziness, which usually resolve over time. However, if the side effects are persistent, reach out to your doctor.

It is highly recommended to take Chlohat 12.5mg Tablet in the morning. Taking it close to bedtime will likely cause you to wake up several times during the night to urinate, disrupting your sleep. Talk to your doctor if you need advice on scheduling your doses.

You should notice an increase in urination within a few hours of your first dose. However, it can take several weeks of consistent daily use before your blood pressure shows a significant, stable reduction. Talk to your doctor if you have concerns about your progress.

Yes, this medicine can cause your body to lose potassium through your urine. Your doctor will likely monitor your potassium levels with regular blood tests and may recommend dietary changes or a supplement. Talk to your doctor before changing your diet.

You should avoid or limit alcohol while taking this medicine. Alcohol can increase the blood pressure-lowering effects of Chlohat 12.5mg Tablet, which can cause severe dizziness, lightheadedness, or fainting when you stand up. Talk to your doctor about safe limits.

Muscle cramps can be a sign that your potassium or sodium levels are too low. You should contact your healthcare provider to check your blood levels. Talk to your doctor before taking any supplements to treat the cramps.

This medicine is generally not recommended during pregnancy because it can reduce blood flow to the placenta. If you are pregnant or planning to become pregnant, talk to your doctor to discuss safer treatment options.

Yes, this medication can make your skin more sensitive to sunlight, increasing your risk of severe sunburns. You should use sunscreen, wear protective clothing, and avoid tanning beds. Talk to your doctor if you develop a severe skin reaction.

No, you should continue taking this medicine even if you feel fine and your blood pressure readings are normal. High blood pressure often has no symptoms, and stopping the medicine can cause your pressure to rise again. Talk to your doctor before making any changes.

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Reference

  1. U.S. Food and Drug Administration (FDA). 019574S016Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. CiplaMed Clinical Compendium. Techlors Product Specification Guide. Mumbai, India: Cipla; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Chlorthalidone Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Drugs and Lactation Database (LactMed®) [Internet]. 2006. [Accessed on 12 Jun, 2023] Check here
  5. Chlorthalidone, EMC UK [Accessed on 3 Sep,2019] Check here
  6. Connor C. Kerndt; Jayesh B. Patel. Chlorthalidone. NIH. National Library of Medicine. National Center of Biotechnology Information. PMC PubMed Central. [Revised in May 2022]. [Accessed on 9th July 2025]Check here

Country of origin

India
Other Info - CH15892
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