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compositionComposition:CHLORTHALIDONE-12.5MG
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Prescription Medicine
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Chlorvix 12.5 Tablet is used to treat high blood pressure, heart failure and oedema (a build-up of fluid in the body). It contains Chlorthalidone, which works by increasing the amount of urine that is passed out from the kidneys. Thereby, it helps treat hypertension and oedema. In some cases, you may experience headaches, nausea or dizziness, which usually resolve over time. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CHLORTHALIDONE-12.5MG

Manufacturer/Marketer :

Elbrit Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Chlorvix 12.5 Tablet

Chlorvix 12.5 Tablet is a prescription medicine used to treat high blood pressure and reduce swelling caused by excess fluid in your body. By helping your kidneys remove extra salt and water, this medication decreases the workload on your heart and blood vessels. Using it consistently helps protect your long-term health by reducing the risk of strokes and heart attacks.

For the best results, you should take Chlorvix 12.5 Tablet at the same time every day, preferably in the morning to prevent having to wake up during the night to urinate. You can take this medicine with or without food, but maintaining a consistent routine is important for steady blood pressure control. Combining this treatment with a low-salt diet and regular, doctor-approved exercise will help you achieve the best possible results.

While taking this medicine, you may experience mild side effects like an increased need to urinate, mild dizziness, or a temporary headache. These symptoms are usually manageable, but you must contact your doctor immediately if you experience serious side effects such as severe muscle cramps, extreme thirst, or an irregular heartbeat.

Before you begin taking Chlorvix 12.5 Tablet , talk to your doctor if you have a history of kidney disease, liver damage, diabetes, gout, or low potassium levels. Do not take this if you are unable to pass urine or if you have a known severe allergy to sulfonamide medications.

Certain medicines, including regular pain relievers and other blood pressure drugs, can interact with Chlorvix 12.5 Tablet and affect how it works. Drinking alcohol while taking this medicine can cause your blood pressure to drop too low, leading to severe dizziness. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist before starting this treatment to ensure it is safe for you.

Uses of Chlorvix 12.5 Tablet

Chlorvix 12.5 Tablet contains chlorthalidone and is used to lower blood pressure and reduce excess fluid accumulation in the body. The detailed uses of Chlorvix 12.5 Tablet are as follows: 

  • High Blood Pressure (Hypertension): Chlorvix 12.5 Tablet helps lower elevated blood pressure, which reduces the workload on your heart and protects your blood vessels from long-term damage.
  • Fluid Retention (Oedema): Chlorvix 12.5 Tablet helps your body eliminate excess water and salt caused by conditions like heart failure, kidney disease, or liver disease, reducing swelling in your limbs.

Key Benefits

Chlorvix 12.5 Tablet helps control blood pressure and reduce excess fluid in the body, supporting cardiovascular health and improving physical comfort.  Regular treatment helps protect against the complications associated with uncontrolled high blood pressure.

  • Long-Lasting Blood Pressure Control: Chlorvix 12.5 Tablet provides sustained blood pressure control throughout the day and night, helping reduce the risk of serious cardiovascular events such as strokes and heart attacks.
  • Relief from Swelling and Fluid Retention: By helping remove excess fluid from the body, Chlorvix 12.5 Tablet reduces swelling in the legs, ankles, and feet, making walking, movement, and other daily activities more comfortable.
Side effects of Chlorvix 12.5 Tablet
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.

Directions for Use

Follow these step-by-step instructions to take your medicine safely:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • Take this medicine in the morning to prevent nighttime sleep disruptions from needing to urinate.
  • You can take your dose with or without food, but try to do it the same way every day.

Always follow your doctor's exact instructions regarding your treatment. Do not stop taking this medication suddenly, even if you feel completely well.

How Chlorvix 12.5 Tablet Works

Chlorvix 12.5 Tablet contains chlorthalidone, which belongs to a group of medicines known as diuretics, commonly called 'water pills.' It acts directly on the filtering units of your kidneys to increase the amount of sodium and water that your body removes from your bloodstream and excretes through your urine. As your body sheds this extra salt and water, the total volume of blood circulating through your blood vessels goes down. This reduction in fluid volume lowers the pressure against your artery walls and decreases the strain on your heart, allowing it to pump blood more easily throughout your body.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Chlorvix 12.5 Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Chlorvix 12.5 Tablet is classified as FDA pregnancy risk category B. So, Chlorvix 12.5 Tablet should not be used during pregnancy unless clearly necessary. Prolonged intake of Chlorvix 12.5 Tablet during pregnancy may cause jaundice (yellowing of skin and eye), unexplained bruising, low blood sugar and electrolyte imbalance in the neonates (newborn baby). Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

Chlorvix 12.5 Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please talk to your doctor.

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Driving

Unsafe

Driving after taking Chlorvix 12.5 Tablet is not recommended as it may occasionally cause drowsiness.

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Liver

Caution

Chlorvix 12.5 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Chlorvix 12.5 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions.

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Children

Caution

Chlorvix 12.5 Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

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Heart

Safe if prescribed

Chlorvix 12.5 Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Chlorvix 12.5 Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Chlorvix 12.5 Tablet

Do not take more than the prescribed dose of Chlorvix 12.5 Tablet as it may cause serious side effects. The symptoms of overdose include drowsiness, dizziness, nausea, weakness, muscle pain, extreme thirst, or rapid heartbeats. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Monitor your sodium intake: Reduce the amount of salt in your meals and avoid processed foods, as excess sodium can prevent Chlorvix 12.5 Tablet from working effectively.
  • Eat potassium-rich foods: Since this medicine can cause your body to lose potassium, include foods like bananas, oranges, spinach, and sweet potatoes in your diet if recommended by your doctor.
  • Stay safely hydrated: Ask your doctor how much fluid you should drink each day, as getting dehydrated can increase the risk of dizziness and kidney strain.
  • Limit alcohol consumption: Avoid or strictly limit alcohol, as it can combine with your medicine to cause a sudden, severe drop in blood pressure.
  • Track your blood pressure: Keep a daily log of your blood pressure readings at home to share with your doctor during your routine check-ups.
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How Soon It Starts Working

  • The time required for Chlorvix 12.5 Tablet to start to work: The time required for Chlorvix 12.5 Tablet to start to work is 3 hours after administration.
  • The time for which the effects of Chlorvix 12.5 Tablet last: The effect of Chlorvix 12.5 Tablet lasts for 24 hours.

What if you forget to take Chlorvix 12.5 Tablet

If you miss a dose of Chlorvix 12.5 Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store Chlorvix 12.5 Tablet tablets at room temperature, ideally between 68°F and 77°F (20°C and 25°C). • Keep the medication inside its original container, tightly closed, to protect it from moisture and direct light. Do not store this medicine in your bathroom

Drug Warnings

  • Stand Up Slowly: Stand up slowly from a sitting or lying position to help reduce the risk of dizziness, lightheadedness, and fainting.
  • Protect Your Skin from Sunlight: Avoid excessive exposure to direct sunlight, as this medicine may increase your sensitivity to sunburn. Wear protective clothing and apply sunscreen when outdoors.
  • Attend Regular Blood Tests: Keep all scheduled blood test appointments so your doctor can monitor your kidney function and electrolyte levels regularly.
  • Monitor Blood Sugar Levels: If you have diabetes, check your blood sugar levels closely, as this medicine may occasionally cause blood sugar levels to increase.
  • Inform Healthcare Providers Before Procedures: Tell your dentist, surgeon, or other healthcare providers that you are taking Chlorvix 12.5 Tablet before undergoing any medical or dental procedures.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Chlorvix 12.5 Tablet : 

  • Lithium: Taking Chlorvix 12.5 Tablet can reduce how quickly your body clears lithium, raising it to dangerous, toxic levels in your bloodstream.
  • NSAIDs (like ibuprofen or naproxen): These common pain relievers can reduce the effectiveness of Chlorvix 12.5 Tablet and increase your risk of kidney damage.
  • Other blood pressure medications: Combining this medicine with other drugs that lower blood pressure can increase the risk of your blood pressure dropping too low.
  • Digoxin: Low potassium levels caused by Chlorvix 12.5 Tablet can increase your risk of developing serious, toxic side effects from digoxin.


Drug-Food Interactions

Certain foods, beverages, and dietary products may affect how Chlorvix 12.5 Tablet works or increase the risk of side effects. Examples include: 

  • Natural Liquorice: Eating natural liquorice can worsen potassium loss when combined with this medication.


Drug-Disease Interactions

Inform your doctor if you have any of the following medical conditions before taking Chlorvix 12.5 Tablet , as additional monitoring or treatment adjustments may be required: 

  • Anuria (Inability to urinate): Do not take this medicine if you are unable to pass urine, as it relies on active kidney function to work.
  • Gout: This medicine can raise uric acid levels in your blood, which may trigger or worsen painful gout attacks.
  • Diabetes: Chlorvix 12.5 Tablet can affect your blood sugar control, which may require your doctor to adjust your diabetes medications.
CarvedilolThioridazine
Critical
CarvedilolRitodrine
Severe

Drug-Drug Interactions

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CarvedilolThioridazine
Critical
How does the drug interact with Chlorvix 12.5 Tablet:
Coadministration of thioridazine with Chlorvix 12.5 Tablet can increase the risk of low blood pressure especially when standing up.

How to manage the interaction:
Taking Thioridazine with Chlorvix 12.5 Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any excessive sweating, palpitations, chest discomfort, or shortness of breath. Do not discontinue any medication without consulting a doctor.
CarvedilolRitodrine
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Co-administration of Ritodrine with Chlorvix 12.5 Tablet it may reduces the effectiveness of both the medications.

How to manage the interaction:
There may be a possibility of interaction between Ritodrine and Chlorvix 12.5 Tablet, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
CarvedilolTizanidine
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Coadministration of Chlorvix 12.5 Tablet and Tizanidine may increase the risk of low blood pressure.

How to manage the interaction:
Taking Chlorvix 12.5 Tablet with Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience symptoms like headache, dizziness, excessive sweating, or palpitations, contact your doctor right away. Do not stop using any medications without a doctor's advice.
CarvedilolDisopyramide
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Taking Chlorvix 12.5 Tablet and Disopyramide can increase the risk of developing side effects.

How to manage the interaction:
There may be a possibility of interaction between Disopyramide and Chlorvix 12.5 Tablet, but it can be taken if prescribed by a doctor. However, contact your doctor immediately if you experience dizziness, palpitations, or shortness of breath. Do not discontinue any medications without consulting your doctor.
CarvedilolVerapamil
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Coadministration of Chlorvix 12.5 Tablet with verapamil can increase the risk or severity of side effects.

How to manage the interaction:
Although there may be an interaction, Chlorvix 12.5 Tablet can be taken with verapamil if prescribed by the doctor. However, consult the doctor if you experience headaches, swelling of legs and hands, shortness of breath, chest pain, or palpitations. Do not discontinue any medications without a doctor's advice.
CarvedilolQuinidine
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Taking Quinidine with Chlorvix 12.5 Tablet can increase the levels and effects of Chlorvix 12.5 Tablet.

How to manage the interaction:
Taking Chlorvix 12.5 Tablet with Quinidine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any dizziness, palpitations, headache, or fatigue, consult your doctor immediately. Do not stop using any medications without first talking to your doctor.
CarvedilolSalbutamol
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Coadministration of Chlorvix 12.5 Tablet and Salbutamol may reduce the effects of both medications.

How to manage the interaction:
Although there is a possible interaction between Chlorvix 12.5 Tablet and Salbutamol, they can be taken if your doctor advises. Consult your doctor if you experience shortness of breath, chest pain or any difficulties in breathing. Do not stop using any medications without a doctor's advice.
CarvedilolPazopanib
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Taking pazopanib with Chlorvix 12.5 Tablet may increase the blood levels of pazopanib.

How to manage the interaction:
Although there is an interaction between Pazopanib and Chlorvix 12.5 Tablet, it can be taken if your doctor has advised it. However, consult a doctor immediately if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting your doctor.
CarvedilolTheophylline
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Taking Chlorvix 12.5 Tablet with theophylline, could make Chlorvix 12.5 Tablet less effective and increase the effects of theophylline.

How to manage the interaction:
Although Chlorvix 12.5 Tablet and theophylline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, restlessness, palpitations, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CarvedilolCeritinib
Severe
How does the drug interact with Chlorvix 12.5 Tablet:
Taking Chlorvix 12.5 Tablet and Ceritinib can increase the risk of an irregular heart rhythms.

How to manage the interaction:
Taking Ceritinib with Chlorvix 12.5 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor if you experience dizziness, shortness of breath, palpitations, or irregular heartbeat. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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CHLORTHALIDONE-12.5MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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CHLORTHALIDONE-12.5MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
The effects of Chlorvix 12.5 Tablet may be reduced if taken along with multivitamins and minerals. Give Chlorvix 12.5 Tablet and multivitamins and minerals at least two hours gap in between doses to avoid interaction. Do not stop taking any medications without consulting a doctor.

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Chlorvix 12.5 Tablet is used to treat high blood pressure (hypertension) and oedema (a build-up of fluid in the body).
Chlorvix 12.5 Tablet works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This, in turn, reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. So, it helps to lower high blood pressure, reducing the chances of a heart attack or stroke.
Taking Chlorvix 12.5 Tablet may cause dehydration. So, to avoid dehydration, drink plenty of fluids and inform your doctor if you feel extremely thirsty.
It is unlikely that Chlorvix 12.5 Tablet affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There is not enough evidence to say for certain. For the best advice, consult your doctor.
Chlorvix 12.5 Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are lifelong conditions and one should not abruptly discontinue them without discussing it with a doctor.
Yes, Chlorvix 12.5 Tablet is a diuretic (water pill), which increasing the amount of urine that is passed out from the kidneys.
Take Chlorvix 12.5 Tablet as prescribed by the doctor. It can be taken daily if advised by the doctor.
You are recommended not to consume alcohol along with Chlorvix 12.5 Tablet to avoid unpleasant side-effects.
Taking more than the recommended dose of Chlorvix 12.5 Tablet may cause serious side effects. The symptoms of overdose include drowsiness, dizziness, nausea, weakness, muscle pain, extreme thirst, or rapid heartbeats. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately. Avoid exceeding the recommended dose and take Chlorvix 12.5 Tablet as advised by the doctor.
Consult the doctor before taking ibuprofen with Chlorvix 12.5 Tablet as dose adjustment may be needed to safely take both the medicines together.
Yes, Chlorvix 12.5 Tablet may increase uric acid levels leading to gout. Inform the doctor if you have gout or if you notice symptoms of gout such as sudden/severe attack of pain, swelling, redness and tenderness in one or more joints.
Chlorvix 12.5 Tablet may not cause skin cancer. However, it might cause sensitivity to sunlight. Wear protective clothing and use sunscreen while going out.
Chlorvix 12.5 Tablet may cause side effects like headaches, nausea or dizziness, which usually resolve over time. However, if the side effects are persistent, reach out to your doctor.
It is highly recommended to take Chlorvix 12.5 Tablet in the morning. Taking it close to bedtime will likely cause you to wake up several times during the night to urinate, disrupting your sleep. Talk to your doctor if you need advice on scheduling your doses.
You should notice an increase in urination within a few hours of your first dose. However, it can take several weeks of consistent daily use before your blood pressure shows a significant, stable reduction. Talk to your doctor if you have concerns about your progress.
Yes, this medicine can cause your body to lose potassium through your urine. Your doctor will likely monitor your potassium levels with regular blood tests and may recommend dietary changes or a supplement. Talk to your doctor before changing your diet.
You should avoid or limit alcohol while taking this medicine. Alcohol can increase the blood pressure-lowering effects of Chlorvix 12.5 Tablet , which can cause severe dizziness, lightheadedness, or fainting when you stand up. Talk to your doctor about safe limits.
Muscle cramps can be a sign that your potassium or sodium levels are too low. You should contact your healthcare provider to check your blood levels. Talk to your doctor before taking any supplements to treat the cramps.
This medicine is generally not recommended during pregnancy because it can reduce blood flow to the placenta. If you are pregnant or planning to become pregnant, talk to your doctor to discuss safer treatment options.
Yes, this medication can make your skin more sensitive to sunlight, increasing your risk of severe sunburns. You should use sunscreen, wear protective clothing, and avoid tanning beds. Talk to your doctor if you develop a severe skin reaction.
No, you should continue taking this medicine even if you feel fine and your blood pressure readings are normal. High blood pressure often has no symptoms, and stopping the medicine can cause your pressure to rise again. Talk to your doctor before making any changes.

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Country of origin

India

Manufacturer/Marketer address

Elbrit Life Sciences Private Limited, Level 4, A Wing, Dynasty Business Park, Andheri Kurla Road, Andheri ( E ), Mumbai 400059.
Other Info - CHL0135
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