Cipzen-D Tablet | Uses, Side Effects, Price

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More about the Product

Composition :

DICLOFENAC-50MG+SERRATIOPEPTIDASE-10MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cipzen-D Tablet

Cipzen-D Tablet is used in the treatment of pain and inflammation associated with various conditions, such as bone or soft tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Cipzen-D Tablet contains Diclofenac and Serratiopeptidase. Diclofenac blocks the action of a chemical messenger (cyclo-oxygenase) that causes pain and swelling at the injured or damaged tissue. Serratiopeptidase helps degrade insoluble protein (fibrin) in blood clots and thin fluids in the affected area, thereby reducing swelling.

Take Cipzen-D Tablet exactly as prescribed by your doctor. Swallow it whole with a glass of water; do not crush, chew, or break it. Cipzen-D Tablet may cause common side effects such as stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Please consult your doctor if the side effects persist or worsen.

Do not take Cipzen-D Tablet if you are allergic to any of its ingredients or to other painkillers such as aspirin, ibuprofen, naproxen, or diclofenac. Avoid taking Cipzen-D Tablet during the last trimester of pregnancy unless advised by your doctor. It is not recommended for use in children. Do not take Cipzen-D Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure).

Uses of Cipzen-D Tablet

Cipzen-D Tablet is used in the treatment of pain. The detailed uses of Cipzen-D Tablet are as follows:

Reduction of pain and inflammation: Cipzen-D Tablet helps relieve pain and swelling associated with various conditions, including bone or soft-tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Health Queries

I have had a cyst-like swelling on my penis for the past 1 month. I took Polyclav 625 and Cipzen D tablets and got temporary relief, but it keeps coming back. What should I do for proper treatment?

Vikas Singh

M Pharmacy

A cyst-like swelling on the penis that keeps coming back may be due to a blocked gland, infection or another local condition that needs proper assessment. Temporary relief with medicines can happen, but it may not treat the root cause. Keep the area clean, avoid squeezing or irritation and maintain good hygiene. Since it has persisted for a month, consult a doctor for proper examination and targeted treatment.

I have serious swelling on my face, and I took Cipzen D. How long will it take to show effect?

Vikas Singh

M Pharmacy

Cipzen D is used to reduce pain and swelling, and it may start showing some relief within a few hours, but full improvement can take a couple of days. The response can vary depending on the cause of the swelling. Try to rest, avoid touching the area and keep your head slightly elevated. If the swelling is severe, worsening or not improving, consult a doctor for proper evaluation.

My triglyceride levels are consistently high (around 500 or more). My levels improved after I took Rosuvas F 10 for a year, but they increased again after I stopped the medication. Please advise why this is happening and whether I need to continue the medication long-term.

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Your triglyceride levels have likely increased because your body cannot manage them without the help of Rosuvas F 10 tablet (Rosuvastatin and Fenofibrate). You may need to continue the medication long term, along with strict diet control, as high triglyceride levels may significantly raise your risk of pancreatitis and heart disease. Please consult your doctor or cardiologist for personalised advice.

I am 33 years old. Is it possible to increase height at this age? Are there any effective medications, and can the advertised drinks or supplements that claim to increase height be trusted?

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

At 33 years old, the growth plates in your bones have already closed, so it is not possible to increase height naturally. There are no safe or effective medications that can make adults taller. Be cautious with drinks or supplements advertised to increase height, as they lack scientific evidence and often contain unnecessary sugar or unregulated ingredients that may be harmful.

Have a query?

Side effects of Cipzen-D Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Loss of appetite

Directions for Use

Cipzen-D Tablet can be taken with or without food. However, taking it with food may help reduce stomach upset.
Follow your doctor's instructions on the dosage and timing of this medication.
Swallow Cipzen-D Tablet as a whole with a glass of water.
Do not crush, chew, or break it.

Key Benefits

Cipzen-D Tablet offers the following medicinal benefits:

Effectively reduces musculoskeletal pain from conditions such as back pain, arthritis, spondylitis, and muscle injuries.
Relieves pain and swelling after surgeries, sprains, fractures, and other soft-tissue injuries.
Helps manage pain associated with toothaches, dental procedures, sore throat, and ear infections.
Supports healing by promoting fluid drainage from swollen tissues, helping inflammation decrease more quickly.

How Cipzen-D Tablet Works

Cipzen-D Tablet contains two medications: Diclofenac and Serratiopeptidase. • Diclofenac: It is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the action of a chemical messenger (cyclo-oxygenase) responsible for causing pain and swelling at the injured or damaged tissue. • Serratiopeptidase: It is a proteolytic enzyme that helps break down insoluble protein (fibrin) in blood clots and thins fluids in the affected area, making it easier for excess fluid to drain and helping to reduce swelling. • Together, these medications help relieve pain and inflammation.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Cipzen-D Tablet

Do not take more than the prescribed dose of Cipzen-D Tablet , as it may cause serious side effects or poisoning. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not take Cipzen-D Tablet if you are allergic to any of its ingredients or to other painkillers such as aspirin, ibuprofen, naproxen, or diclofenac.
Avoid taking Cipzen-D Tablet during the last trimester of pregnancy unless advised by your doctor.
Cipzen-D Tablet is not recommended for use in children.
Do not take Cipzen-D Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure).
Do not drive or operate heavy machinery after intake of Cipzen-D Tablet , as it may cause dizziness.
Patients who have recently undergone heart bypass surgery should take Cipzen-D Tablet with caution and only under medical supervision.
Use of Cipzen-D Tablet is contraindicated in patients with kidney failure or those undergoing dialysis.

Drug-Drug Interactions

DiclofenacMeloxicam

Critical

DiclofenacDalteparin

Severe

Drug-Drug Interactions

DiclofenacMeloxicam

Critical

How does the drug interact with Cipzen-D Tablet:
Co-administration of Cipzen-D Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Cipzen-D Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.

DiclofenacDalteparin

Severe

How does the drug interact with Cipzen-D Tablet:
Co-administration use of Cipzen-D Tablet with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Cipzen-D Tablet may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.

DiclofenacDasatinib

Severe

How does the drug interact with Cipzen-D Tablet:
Taking Dasatinib together with Cipzen-D Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Cipzen-D Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.

DiclofenacCidofovir

Severe

How does the drug interact with Cipzen-D Tablet:
Coadministration of Cipzen-D Tablet with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Cipzen-D Tablet and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

DiclofenacPrasugrel

Severe

How does the drug interact with Cipzen-D Tablet:
Taking prasugrel together with Cipzen-D Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Cipzen-D Tablet and Prasugrel can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

DiclofenacHuman immunoglobulin

Severe

How does the drug interact with Cipzen-D Tablet:
Taking Cipzen-D Tablet with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Cipzen-D Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

DiclofenacIndometacin

Severe

How does the drug interact with Cipzen-D Tablet:
The combined use of Cipzen-D Tablet and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Cipzen-D Tablet and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

DiclofenacDabigatran etexilate

Severe

How does the drug interact with Cipzen-D Tablet:
Concomitant use of Cipzen-D Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Cipzen-D Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.

DiclofenacTenofovir alafenamide

Severe

How does the drug interact with Cipzen-D Tablet:
Co-administration of Cipzen-D Tablet and tenofovir alafenamide may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Cipzen-D Tablet and Tenofovir alafenamide but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.

DiclofenacTenofovir disoproxil

Severe

How does the drug interact with Cipzen-D Tablet:
Co-administration of Cipzen-D Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Cipzen-D Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Diet & Lifestyle Advise

Dietary supplements:

Include supplements rich in glucosamine, chondroitin sulphate, vitamin D, and calcium.
Turmeric and fish oils can help reduce inflammation in the tissues.

Anti-inflammatory foods:

Include fatty fish like salmon, trout, tuna, and sardines in your diet. These are rich in omega-3 fatty acids that help reduce inflammation.

Physical activity:

Avoid heavy exercise, as it may exacerbate joint pain in arthritis.
Focus on stretching and low-impact aerobic exercise, such as walking on a treadmill, cycling, or swimming.
Strengthen muscles with light weightlifting to support joint health.

Posture and sitting habits:

Avoid prolonged sitting; keep sitting periods short (10-15 minutes).
Use back support, such as a rolled-up towel, to maintain the natural curve of your spine.
Keep your knees and hips at right angles while sitting.
Use a footrest if needed to reduce strain.

Habit Forming

Therapeutic Class

[ANALGESICS]

Alcohol

Caution

You are recommended not to consume alcohol along with Cipzen-D Tablet to avoid unpleasant side effects.

Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant before taking Cipzen-D Tablet .

Breast Feeding

Caution

Cipzen-D Tablet may enter breast milk. Consult your doctor for more information on this if you are a breastfeeding mother.

Driving

Caution

Cipzen-D Tablet may impair driving, as it can cause dizziness. Drive or operate machinery only when you are alert.

Liver

Caution

Cipzen-D Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

Kidney

Caution

Cipzen-D Tablet to be taken with caution if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

Children

Caution

Cipzen-D Tablet is not recommended for children under 10 years of age. For them, the dose must be adjusted and recommended only by a child specialist.

Heart

Unsafe

Cipzen-D Tablet should be avoided in cardiac patients, as it can lead to serious cardiovascular risks

Geriatrics

Caution

Cipzen-D Tablet should be used with caution in geriatric patients, as it can cause serious side effects.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.

Other Info - CIP0006

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Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Feb 11, 2026 | 12:39 PM IST

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Vikas Singh

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