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compositionComposition:CLEMASTINE-0.5MG
prescription
Prescription Medicine
info
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Clamist Oral Solution is used to treat allergic rhinitis and urticaria. It contains Clemastine which works by blocking the action of histamine that causes allergic symptoms. In some cases, this medicine may cause side effects such as dizziness, drowsiness, dry mouth, and changes in vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CLEMASTINE-0.5MG

Manufacturer/Marketer :

Wanbury Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Clamist Oral Solution

Clamist Oral Solution is an antihistamine used to relieve symptoms of allergies, hay fever, and the common cold. It helps ease irritating issues like sneezing, a runny nose, watery eyes, and itchy skin or hives. By blocking certain natural substances in your body, it provides reliable comfort from seasonal and year-round allergy triggers.

To get the most benefit, you should take this medication consistently at the times recommended by your healthcare provider, often once or twice daily. You can take Clamist Oral Solution with or without food, though taking it with a glass of water or a meal can help if you have a sensitive stomach. Drinking plenty of water throughout the day can also help manage mild dryness in your mouth or throat.

While taking Clamist Oral Solution, you might experience mild side effects like sleepiness, dry mouth, or mild dizziness. These are common and often fade as your body gets used to the medicine. However, if you experience serious issues like a very fast heartbeat, severe dizziness, or difficulty urinating, stop taking the medicine and consult your doctor immediately.

Do not take this if you have certain medical conditions, such as narrow-angle glaucoma or a blockage in your bladder or stomach. It is also important to talk to your doctor before starting Clamist Oral Solution if you have asthma, chronic bronchitis, high blood pressure, or an enlarged prostate.

This medicine can interact with other substances; for example, combining it with alcohol or sleeping pills can make you extremely drowsy and slow your reactions. If you are pregnant, breastfeeding, or over the age of 65, consult your doctor or pharmacist before using Clamist Oral Solution to ensure it is safe for your specific needs.

Use Clamist Oral Solution only for as long as recommended by your doctor. Many people experience relief within 1 to 2 hours of taking a dose, but if your allergy symptoms do not improve after several days, worsen, or keep coming back, consult your doctor. Do not continue using this medicine for prolonged periods without medical advice, as your treatment may need to be reassessed. 

Uses of Clamist Oral Solution

Your doctor may prescribe this medicine to treat several conditions, including:

  • Allergic rhinitis (hay fever): It relieves sneezing, runny nose, and itchy, watery eyes caused by seasonal outdoor allergens like pollen or indoor allergens like dust mites and pet dander.
  • Hives (urticaria): It reduces skin itching, swelling, and redness associated with allergic skin reactions and hives.
  • Common cold symptoms: It helps dry up a runny nose and stops sneezing associated with early cold symptoms.

Key Benefits

Clamist Oral Solution helps relieve allergy symptoms by blocking the effects of histamine, a substance released during allergic reactions. It provides effective relief from common allergy symptoms and improves day-to-day comfort. Key benefits include:

  • Relieves Allergy Symptoms: By reducing the effects of histamine, Clamist Oral Solution helps relieve sneezing, runny nose, itchy or watery eyes, and other symptoms associated with allergic conditions.
  • Reduces Itching and Hives: Clamist Oral Solution helps relieve itching, redness, and discomfort caused by hives and other allergic skin reactions, reducing the urge to scratch and protecting the skin.
  • Improves Daily Comfort: By controlling allergy symptoms, Clamist Oral Solution helps you sleep better, stay focused during the day, and carry out daily activities with greater comfort.

Directions for Use

  • Clamist Oral Solution can be taken with or without food. However, if you experience stomach upset, take it with food.
  • It is usually taken 2-3 times daily or as prescribed by your doctor.
  • Swallow Clamist Oral Solution as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Clamist Oral Solution Works

When your body encounters an allergen like pollen or dust, it releases a natural chemical called histamine. Histamine attaches to tiny receptors in your eyes, nose, and skin, causing inflammation, swelling, itching, and mucus production. Clamist Oral Solution contains clemastine which works by blocking these histamine receptors (specifically the H1 receptors) in your body. By preventing histamine from binding to its targets, the medicine stops the allergic reaction in its tracks. This drying and calming action is what relieves your runny nose, watery eyes, and itchy skin. Clamist Oral Solution belongs to a group of medicines called first-generation antihistamines. While it is effective at relieving allergy symptoms, it is more likely to cause drowsiness, dizziness, dry mouth, and slowed reaction times than newer (second-generation) antihistamines such as cetirizine or fexofenadine. Your doctor may choose Clamist Oral Solution when its benefits outweigh these effects, but you should take extra care when performing activities that require alertness.
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Alcohol

Caution

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness and difficulty in concentration. It is advised that you do not perform any activities that require high mental alertness, like driving a vehicle or operating machinery, if you consume alcohol during treatment with this medicine.

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Pregnancy

Caution

Clamist Oral Solution is not recommended for use in pregnancy unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

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Breast Feeding

Caution

Clamist Oral Solution is not recommended for use in breastfeeding unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

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Driving

Caution

Clamist Oral Solution may decrease your alertness and vision or make you sleepy and dizzy. Do not drive if these symptoms occur. Caution is advised when driving or operating machinery.

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Liver

Caution

Clamist Oral Solution should be used with caution if you have liver disease. Dose adjustment may be needed. Please consult your doctor before taking Clamist Oral Solution.

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Kidney

Caution

Clamist Oral Solution is probably safe to use if you have kidney disease. Dose adjustment may be needed. Please consult your doctor before taking Clamist Oral Solution.

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Children

Safe

Clamist Oral Solution can be safely used in children aged six years and above with a doctor's prescription. It is not recommended for children below six years.

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Heart

Caution

Clamist Oral Solution should be taken with caution in patients with heart problems due to the risk of increased heart rate or palpitations. Please inform your doctor about any existing heart problems before using Clamist Oral Solution.

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Geriatrics

Unsafe

Clamist Oral Solution is not safe for use in elderly patients due to its serious side effects.

What if I have taken an overdose of Clamist Oral Solution

If you suspect an overdose, seek emergency medical attention or contact a poison control centre immediately. Symptoms of an overdose can include extreme drowsiness, confusion, widening of the pupils, flushed skin, or excitement and restlessness (especially in children).

Diet & Lifestyle Advise

  • Reduce exposure to allergens: Keep windows closed during high-pollen seasons and use air conditioning to help filter airborne allergens from your indoor environment.
  • Minimise dust mite exposure: Wash your bedding weekly in hot water to help reduce dust mites and other common indoor allergens.
  • Relieve dry mouth: If this medicine causes dry mouth, chew sugar-free gum, suck on ice chips, or sip water regularly to help keep your mouth moist and comfortable.
  • Limit outdoor exposure during peak pollen times: Avoid outdoor activities in the early morning when pollen counts are typically at their highest.
  • Wash away pollen after being outdoors: Shower and change into clean clothes after spending time outside to remove pollen from your skin, hair, and clothing.
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How Soon It Starts Working

The time required for Clamist Oral Solution to start to work: Clamist Oral Solution ideally shows its action within 15 to 60 minutes after administration. The time for which the effects of Clamist Oral Solution last: The effect of Clamist Oral Solution lasts for 8 to 12 hours.

What if you forget to take Clamist Oral Solution

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Clamist Oral Solution at room temperature between 20°C and 25°C (68°F to 77°F) in its original, tightly closed container. Protect it from moisture, heat, and direct light.•Do not flush it down the toilet.

Drug Warnings

  • Avoid driving or operating machinery: Clamist Oral Solution may cause significant drowsiness, dizziness, and slowed reaction times. Do not drive or perform hazardous tasks until you know how this medicine affects you.
  • Avoid alcohol: Drinking alcohol while taking Clamist Oral Solution can greatly increase drowsiness, dizziness, and impaired coordination.
  • Check other medicine labels carefully: Many over-the-counter cough, cold, and allergy medicines also contain antihistamines. Taking them with Clamist Oral Solution can increase the risk of excessive drowsiness and accidental overdose.
  • Tell your doctor before allergy testing: If you are scheduled for an allergy skin test, inform your doctor that you are taking Clamist Oral Solution. You may need to stop the medicine several days beforehand because it can affect the test results.
  • Older adults should use extra caution: Older adults may be more sensitive to the sedative and anticholinergic effects of Clamist Oral Solution. Contact your doctor if you experience excessive drowsiness, confusion, dizziness, difficulty passing urine, or repeated falls.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you have a history of the following conditions before using Clamist Oral Solution, as they may affect your treatment.

  • Sedatives, tranquillisers, and sleeping pills: Taking these with Clamist Oral Solution can cause extreme drowsiness and dangerous breathing difficulties.
  • Other antihistamines: Can increase the risk of side effects like dry mouth, blurred vision, and severe sleepiness.
  • MAO inhibitors (antidepressants): May prolong and intensify the drying and sedative effects of this medication.
ClemastinePotassium chloride
Critical
ClemastinePotassium citrate
Critical

Drug-Drug Interactions

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ClemastinePotassium chloride
Critical
How does the drug interact with Clamist Oral Solution 60 ml:
Taking Clamist Oral Solution 60 ml and Potassium chloride(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Clamist Oral Solution 60 ml with Potassium chloride is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
ClemastinePotassium citrate
Critical
How does the drug interact with Clamist Oral Solution 60 ml:
Taking Clamist Oral Solution 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Clamist Oral Solution 60 ml with Potassium citrate is not recommended, as it may lead to an interaction but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ClemastineTopiramate
Severe
How does the drug interact with Clamist Oral Solution 60 ml:
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Clamist Oral Solution 60 ml.

How to manage the interaction:
Co-administration of Clamist Oral Solution 60 ml with Topiramate can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms, like less sweating, feeling hotter, heat stroke, feeling sleepy, dizzy, or lightheaded, it's important to contact your doctor immediately. Do not stop using any medications without talking to your doctor.
ClemastineZonisamide
Severe
How does the drug interact with Clamist Oral Solution 60 ml:
Coadministration of Clamist Oral Solution 60 ml with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Clamist Oral Solution 60 ml with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Can significantly increase drowsiness, dizziness, and mental impairment when combined with this medicine.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIHISTAMINE]

FAQs

Clamist Oral Solution is used to treat allergic conditions like allergic rhinitis and urticaria.
Depending upon the severity of allergic conditions due to allergens Clamist Oral Solution can be safely taken daily or as long as your doctor has advised you to take it.
Clamist Oral Solution is an antihistamine providing instant relief from allergic conditions however, in some people it may cause sleepiness and induce some drowsiness in the day.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Clamist Oral Solution and skip the missed dose. Do not take extra medicine to make up the missed dose.
Clamist Oral Solution cause common side effects like dizziness, drowsiness, dryness in mouth, changes in vision. These side effects resolves on it own. If it persists,stop taking this medicine and consult your doctor.
Clamist Oral Solution works by blocking the action of certain chemical messengers that are responsible for inflammation, congestion, itching and other allergic reactions
Consumption of alcohol is not recommended during treatment with Clamist Oral Solution due to the increased risk of side effects such as dizziness, drowsiness, and difficulty in concentration.
Clamist Oral Solution starts working within 2-3 hours, with the maximum effect kicking in around 5-7 hours after taking the dose. Complete the course of treatment as prescribed by the doctor to get maximum benefits of Clamist Oral Solution.
Do not exceed the recommended dose as prescribed by your doctor as it may cause an overdose. Overdose symptoms of Clamist Oral Solution may include difficulty in breathing, changes in vision, irregular heartbeat, and seizures. If you experience any of these symptoms consult your doctor immediately.
Since Clamist Oral Solution can make you very sleepy, it is often best taken in the evening. If your doctor directs you to take it during the day, use caution when performing tasks that require alertness. Talk to your doctor or pharmacist for personalised advice.
You should consult your doctor before using Clamist Oral Solution if you are pregnant or planning to become pregnant. Your doctor will help weigh the benefits against any potential risks to your baby.
Clamist Oral Solution can be used in children, but the safe age limit and dosage depend on the specific formulation. Never give this medication to a child without consulting a paediatrician first.
Yes, dry mouth is a common side effect of this medication. You can manage this by sipping water, sucking on ice chips, or chewing sugar-free gum. If dry mouth persists or becomes severe, talk to your doctor or pharmacist.
Some blood pressure medications can interact with antihistamines, or your underlying high blood pressure might require cautious use of this drug. Always talk to your doctor or pharmacist before combining these treatments.
While caffeine may temporarily reduce drowsiness, it is not a safe way to counter the strong sedative effects of this medicine. If you find the drowsiness unmanageable, talk to your doctor about alternative options.
If your symptoms do not get better after a few days of treatment, or if they get worse, do not increase your dose on your own. Talk to your doctor to see if a different medication or treatment plan is right for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Clemastine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. MIMS Drug Reference Compendium. Clemastine Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 01 Apr. 2019]Check here
  6. Article.Htm. [Accessed on 02 Jun. 2026]Check here
  7. Clemastine Fumarate Syrup (Clemastine Fumarate Syrup): Side Effects, Uses, Dosage, Interactions, Warnings. [Accessed on 02 Jun. 2026]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
Other Info - CLA0022
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