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compositionComposition:CLONAZEPAM-0.5MG+ESCITALOPRAM-10MG
prescription
Prescription Medicine
info
Clonotril Plus Tablet 10's
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

CLONAZEPAM-0.5MG+ESCITALOPRAM-10MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Clonotril Plus Tablet 10's

Clonotril Plus Tablet 10's is a prescription medicine used to help manage anxiety disorders, panic attacks, and depression. It combines two medicines that work together to reduce excessive anxiety, improve mood, and promote emotional stability. By helping restore the balance of certain brain chemicals, it can make daily activities easier and improve overall quality of life.

Take Clonotril Plus Tablet 10's exactly as prescribed by your doctor. The dosing schedule varies depending on your condition, response to treatment, and your doctor's recommendations. While escitalopram is commonly taken once daily, clonazepam may be prescribed once or more than once daily. Always follow your doctor's specific instructions regarding when and how often to take this medicine. Following healthy lifestyle habits, such as regular exercise, good sleep hygiene, and stress-management techniques, may further support treatment outcomes.

Some people may experience mild side effects such as drowsiness, dry mouth, dizziness, or nausea when starting treatment. These effects are often temporary and may improve as the body adjusts to the medicine. Contact your doctor immediately if you experience severe mood changes, suicidal thoughts, unusual behaviour, difficulty breathing, or any serious allergic reaction.

Before taking Clonotril Plus Tablet 10's, inform your doctor if you have a history of liver disease, kidney problems, glaucoma, or any mental health condition. This medicine may not be suitable for people with severe liver disease, severe breathing difficulties, or known allergies to any of its ingredients. Your doctor may recommend regular monitoring to ensure the treatment remains safe and effective.

Avoid alcohol while taking this medicine, as it can increase drowsiness and may slow breathing. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, or if you are older than 65 years, so they can determine whether this medicine is appropriate for you. Also inform your doctor about any sleeping pills, sedatives, or other medicines you are taking, as they may interact with this treatment.

Uses of Clonotril Plus Tablet 10's

Clonotril Plus Tablet 10's is used to manage anxiety disorders, panic attacks, and depression. The detailed uses of Clonotril Plus Tablet 10's are as follows:

  • Comorbid Depression and Anxiety: Clonotril Plus Tablet 10's helps relieve symptoms of clinical depression while simultaneously calming the physical and mental symptoms of anxiety.
  • Panic Disorder: This medicine helps reduce the frequency and severity of sudden, unexpected panic attacks.
  • Generalised Anxiety Disorder (GAD): Clonotril Plus Tablet 10's helps manage persistent, excessive worry that interferes with daily life.

Key Benefits

Clonotril Plus Tablet 10's helps support mental wellbeing by addressing symptoms of anxiety and mood-related conditions. By combining complementary active ingredients, it promotes emotional balance, reduces distressing symptoms, and helps improve day-to-day functioning.

  • Helps Reduce Anxiety and Feelings of Panic: By calming excessive nervous activity in the brain, Clonotril Plus Tablet 10's helps relieve symptoms such as intense worry, nervousness, and panic, allowing you to feel more relaxed and in control.
  • Supports a More Stable Mood: Clonotril Plus Tablet 10's helps improve emotional balance over time, contributing to a steadier mood and helping reduce the impact of anxiety or mood-related symptoms on daily life.
  • Improves Daily Functioning and Sleep Quality: As symptoms become better controlled, Clonotril Plus Tablet 10's can make it easier to participate in everyday activities, maintain social interactions, engage in therapy, and enjoy more restful sleep.
Side effects of Clonotril Plus Tab
  • Approach calmly, use a non-threatening tone, actively listen, validate concerns, and provide clear instructions.
  • Practice environmental changes like adjusting lighting, noise levels, and providing a safe space.
  • Recognizing and praising desired behaviors.
  • Maintaining consistent schedules for daily activities.
  • Try to engage in calming activities to redirect focus.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Incorporate foods high in omega-3 fatty acids, such as fatty fish (salmon, tuna, mackerel), flaxseeds, into your diet to support brain health and cognitive function.
  • Limit processed meals, sugary drinks, and harmful fats, which can lead to inflammation and negatively impact cognitive abilities.
  • Engage in intellectually stimulating activities, such as reading, puzzles, or learning new skills, to challenge and strengthen your brain.
  • Practice stress-reducing techniques like mindfulness, deep breathing, or meditation to maintain healthy stress levels and support cognitive performance.
  • Prioritize 7-8 hours of quality sleep daily and establish a relaxing bedtime routine to promote brain health and cognitive function.
  • Participate in social activities and keep up your neighbourhood relationships. Social engagement can lower the risk of cognitive decline and enhance cognitive performance.
  • Regular eye exams can detect conditions causing Involuntary Eye Movement.
  • Alcohol and drugs should be avoided as they can increase the symptoms of nystagmus.
  • Wearing corrective lenses for refractive errors can reduce eye strain and symptoms.
  • Stress management and getting proper sleep can help to reduce symptoms.
  • Mood swings can be managed but cannot be controlled. Therefore, spending time in nature can help you feel light and improve your mood.
  • Practice meditation, deep breathing and do regular exercise that can positively affect your mood. Also helps in processing the situation before responding to it.
  • Food has direct impact on mood. Therefore, eat foods that are less processed and reduce sugar intake.
  • Consult your doctor if the mood swings are uncontrollable or unmanageable.

Directions for Use

  • Clonotril Plus Tablet 10's can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Clonotril Plus Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Clonotril Plus Tablet 10's Works

Clonotril Plus Tablet 10's contains clonazepam and escitalopram. It works by balancing chemical messengers in your brain that control mood and anxiety levels. The first active component, escitalopram, is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the levels of serotonin, a natural chemical in the brain that helps maintain mental balance and improves your mood. The second active component, clonazepam, is a benzodiazepine. It works by enhancing the effects of gamma-aminobutyric acid (GABA), a natural calming chemical in the brain that slows down excessive nerve activity to quickly reduce anxiety and muscle tension.
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Alcohol

Caution

Do not take alcohol as it can increase the risk of side-effects.

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Pregnancy

Unsafe

Clonotril Plus Tablet 10's may show toxic effects on the fetus. So, it is not recommended for use in women who are pregnant or planning pregnancy. Consult your doctor for further advice.

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Breast Feeding

Caution

Clonotril Plus Tablet 10's should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.

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Driving

Caution

Do not drive or operate heavy machinery as Clonotril Plus Tablet 10's may cause drowsiness.

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Liver

Caution

Clonotril Plus Tablet 10's should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.

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Kidney

Caution

Clonotril Plus Tablet 10's should be used with caution in patients with kidney failure.

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Children

Caution

Clonotril Plus Tablet 10's should not be used in children unless prescribed by a child specialist.

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Heart

Caution

Exercise caution before using Clonotril Plus Tablet 10's in case of heart problems. Please consult your doctor if you have any concerns. Dosage adjustments may be needed based on your condition

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Geriatrics

Caution

Exercise caution before using Clonotril Plus Tablet 10's in older patients. Please consult your doctor if you have any concerns.

What if I have taken an overdose of Clonotril Plus Tablet 10's

If you suspect an overdose, seek emergency medical attention or contact a poison control centre immediately. Symptoms of an overdose may include extreme drowsiness, confusion, slowed reflexes, or difficulty breathing.

Diet & Lifestyle Advise

  • Limit or avoid caffeine intake, as stimulants like coffee, tea, and energy drinks can worsen anxiety symptoms and interfere with the calming effects of this medication.
  • Avoid alcohol completely, because it can dangerously increase the drowsy side effects of this medicine and worsen symptoms of depression.
  • Establish a consistent bedtime routine to help manage sleep disturbances, which are common when starting this medication.
  • Engage in gentle physical activities, such as walking or yoga, which naturally boost mood-regulating chemicals in the brain.

Have a query?

How Soon It Starts Working

The time required for Clonotril Plus Tablet 10's to start to work: Clonotril Plus Tablet 10's ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Clonotril Plus Tablet 10's last: The effect of Clonotril Plus Tablet 10's lasts for 8 to 12 hours.

What if you forget to take Clonotril Plus Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Clonotril Plus Tablet 10's according to the storage instructions provided on the product packaging or package insert.

Drug Warnings

  • Do not stop taking this medication suddenly, as doing so can cause severe withdrawal symptoms like rebound anxiety, tremors, or sleep problems.
  • Avoid driving, operating heavy machinery, or performing dangerous tasks until you know how this medicine affects your coordination and alertness.
  • Inform your surgeon or dentist that you are taking this medicine before undergoing any medical procedures or surgeries.
  • Check your prescription refills in advance so you do not run out of medication, as maintaining a continuous schedule is critical.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Monoamine Oxidase Inhibitors (MAOIs): Combining these can lead to a life-threatening condition called serotonin syndrome.
  • Other central nervous system depressants (like sleeping pills, muscle relaxants, or opioid pain medicines): May cause extreme drowsiness, slowed breathing, or coma.
  • NSAIDs and blood-thinning medicines: Medicines such as aspirin, ibuprofen, naproxen, warfarin, and other anticoagulants or antiplatelet agents may increase the risk of unusual bleeding or bruising when taken with Clonotril Plus Tablet 10's. Consult your doctor before combining these medicines.

 

Drug-Disease Interactions

  • Liver or kidney damage: These organs clear the medication from your body, so impaired function may require a lower dose to avoid buildup.
  • Glaucoma (narrow-angle): This medicine can worsen pressure inside the eye.
  • Seizure disorders: Stopping this medication abruptly can trigger or worsen seizures.
Escitalopram + ClonazepamSodium oxybate
Critical
Escitalopram + ClonazepamOxaliplatin
Severe

Drug-Drug Interactions

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Escitalopram + ClonazepamSodium oxybate
Critical
How does the drug interact with Clonotril Plus Tab:
Taking Escitalopram and Clonazepam with Sodium oxybate can enhance the side effects

How to manage the interaction:
Taking Clonazepam and Clonazepam together with Sodium oxybate is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as difficulty breathing, low blood pressure, fainting, drowsiness, dizziness, lightheadedness, confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Escitalopram + ClonazepamOxaliplatin
Severe
How does the drug interact with Clonotril Plus Tab:
Combining Escitalopram and Clonazepam with Oxaliplatin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Escitalopram ,Clonazepam and Oxaliplatin, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
Escitalopram + ClonazepamArsenic trioxide
Severe
How does the drug interact with Clonotril Plus Tab:
Combining Escitalopram and Clonazepam with Arsenic trioxide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Escitalopram and Clonazepam together with Arsenic trioxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like dizziness, fainting, abnormal heart rhythm, or difficulty breathing, contact a doctor right away. Do not stop using any medications without a doctor's advice.
Escitalopram + ClonazepamRemifentanil
Severe
How does the drug interact with Clonotril Plus Tab:
Combining Escitalopram and Clonazepam with Remifentanil can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in your body) and side effects such as breathing difficulty.

How to manage the interaction:
Taking Escitalopram and Clonazepam together with Remifentanil can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like confusion, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, diarrhea, dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
Escitalopram + ClonazepamTacrolimus
Severe
How does the drug interact with Clonotril Plus Tab:
Taking Escitalopram and Clonazepam together with Tacrolimus can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking escitalopram and Clonazepam together with tacrolimus can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath or heart palpitations. Do not stop using any medications without consulting a doctor.
Escitalopram + ClonazepamTrazodone
Severe
How does the drug interact with Clonotril Plus Tab:
Combining Escitalopram and Clonazepam with Trazodone can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Escitalopram and Clonazepam together with Trazodone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience confusion, seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, tremors (shaking of hands & legs), incoordination, stomach pain, nausea, vomiting, and diarrhoea, sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact a doctor right away. Do not discontinue any medications without first consulting a doctor.
Escitalopram + ClonazepamMethadone
Severe
How does the drug interact with Clonotril Plus Tab:
Co-administration of Escitalopram and Clonazepam with Hydromorphone may cause serious side effects like breathing difficulty.

How to manage the interaction:
Although taking Escitalopram and Clonazepam together with Hydrocodone can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination, make sure to call a doctor right away. Do not stop using any medications without consulting a doctor.
Escitalopram + ClonazepamTetrabenazine
Severe
How does the drug interact with Clonotril Plus Tab:
Co-administration of Escitalopram and Clonazepam with Tetrabenazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Escitalopram and Clonazepam with Tetrabenazine can lead to an interaction, but it can be taken if your doctor advises. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
Escitalopram + ClonazepamFrovatriptan
Severe
How does the drug interact with Clonotril Plus Tab:
Taking Escitalopram and Clonazepam with Frovatriptan may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Escitalopram, Clonazepam and Frovatriptan they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting and diarrhea. Do not discontinue any medications without consulting a doctor.
Escitalopram + ClonazepamBuprenorphine
Severe
How does the drug interact with Clonotril Plus Tab:
When Escitalopram and Clonazepam is used with Buprenorphine, it may lead to significant adverse effects such as respiratory difficulties and can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Escitalopram and Clonazepam alongside Buprenorphine can result in an interaction, it can be taken if a doctor has advised it. You should avoid driving or operating hazardous machinery. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[ANXIOLYTICS]

FAQs

Clonotril Plus Tablet 10's is used to treat anxiety disorders.

Long-term use of Clonotril Plus Tablet 10's may cause suicidal thoughts in some cases. So, use Clonotril Plus Tablet 10's as prescribed by your doctor. Consult your doctor immediately if you notice any behavioural changes during the use of Clonotril Plus Tablet 10's.

Clonotril Plus Tablet 10's can affect mood or behaviour. However, you should not take this medication without a doctor’s advice.

Anxiety is a feeling of fear, worry or uneasiness. Symptoms include irritability, lack of concentration, fatigue, trembling and rapid heartbeat. If you experience repeated episodes of anxiety, consult a doctor immediately.

Clonotril Plus Tablet 10's may cause a decrease in sexual desire (libido) in men and women. Men can also experience erectile dysfunction. Consult a doctor if you experience any change in sexual desire after taking Clonotril Plus Tablet 10's.

Clonotril Plus Tablet 10's may cause drowsiness. So, do not drive or operate heavy machinery while taking Clonotril Plus Tablet 10's.

Yes, Clonotril Plus Tablet 10's may cause hair loss ina few people. If you experience excessive hair loss please consult your doctor.

Clonotril Plus Tablet 10's is a combination medicine used to treat anxiety disorders.

No, do not take a higher than the recommended dose of Clonotril Plus Tablet 10's as it may cause an overdose. Take Clonotril Plus Tablet 10's according to the dose and duration prescribed by the doctor to prevent any unpleasant side effects.

Store Clonotril Plus Tablet 10's at room temperature, protected from light and moisture. Do not freeze. Keep it out of sight and reach of children.

Do not discontinue Clonotril Plus Tablet 10's without consulting your doctor as it might cause withdrawal symptoms. To treat your condition effectively, keep taking Clonotril Plus Tablet 10's for the prescribed duration. Talk to the doctor if you experience any difficulty while taking Clonotril Plus Tablet 10's.

The clonazepam component may help reduce anxiety symptoms relatively quickly, often within the first few days of treatment. However, the full antidepressant and anti-anxiety benefits of the escitalopram component generally take 4 to 6 weeks of consistent use to become fully apparent. Continue taking the medicine as prescribed and talk to your doctor if your symptoms are not improving.

You should avoid drinking alcohol while taking this medicine. Alcohol can increase drowsiness, impair your judgement, and make your anxiety or depression worse. Talk to your doctor or pharmacist if you have concerns about alcohol use.

Because this medication contains clonazepam, there is a risk of physical and psychological dependence, especially with long-term use. Your doctor will monitor your treatment closely to minimise this risk. Talk to your doctor for more information on safe use.

This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits outweigh the risks to the baby. Talk to your doctor to discuss safer treatment options.

Certain pain relievers, like ibuprofen or aspirin, can increase your risk of bleeding when taken with this medication. Acetaminophen is generally a safer option, but you should always talk to your doctor or pharmacist before combining treatments.

Dry mouth is a common and usually harmless side effect. You can manage it by chewing sugarless gum, sucking on ice chips, or drinking water regularly. Talk to your doctor if this symptom becomes severe or bothersome.

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Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India.
Other Info - CLO0084

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