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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Coldles Plus Oral Suspension is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. It contains Phenylephrine, Paracetamol, and Cetirizine. Phenylephrine works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Cetirizine helps to relieve symptoms of allergy.

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About Coldles Plus Oral Suspension

Coldles Plus Oral Suspension is used to treat symptoms of the common cold and allergies, such as sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as rhinovirus. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks.

Coldles Plus Oral Suspension is a combination of three drugs, namely, Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Cetirizine (antihistamine/antiallergic). Phenylephrine works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Cetirizine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to relieve symptoms of allergy.

Use Coldles Plus Oral Suspension as prescribed. Your doctor will recommend how often your child needs to take Coldles Plus Oral Suspension based on his/her medical condition. Sometimes, Coldles Plus Oral Suspension may cause common side effects such as drowsiness, headache, nausea, vomiting, and dry mouth. Most of these side effects of Coldles Plus Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If your child is allergic to Phenylephrine, Paracetamol, Cetirizine or any other medicines, please tell your doctor. If your child is suffering from any medical condition or is under any specific medication, please inform your doctor before using this medicine. Please do not give more than the prescribed dose of Coldles Plus Oral Suspension to your child.

Uses of Coldles Plus Oral Suspension

Coldles Plus Oral Suspension is used in the treatment of the common cold and allergies in children. The detailed uses of Coldles Plus Oral Suspension are as follows:

  • Treatment of the common cold:Coldles Plus Oral Suspension is used to treat common cold symptoms, including nasal congestion, stuffiness, and breathing difficulties, by reducing swelling in the nasal passages.
  • Decreasing symptoms of allergies:Coldles Plus Oral Suspension can effectively work in alleviating allergy symptoms like a runny nose and sneezing, providing relief from common allergens.
  • Reducing fever:Coldles Plus Oral Suspension is also involved in reducing fever associated with colds and flu, providing relief and comfort.

Directions for Use

  • Coldles Plus Oral Suspension should be taken after meals to reduce side effects like nausea and for better absorption.
  • Follow your doctor’s instructions on the dosage and timing of this medication, or use it as per the labelled instructions.
  • Shake the bottle well before each use.
  • Give the prescribed dose to your child by mouth using the measuring cup provided with the pack
  • Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Coldles Plus Oral Suspension contains Phenylephrine, Paracetamol, and Cetirizine. Phenylephrine works by shrinking the blood vessels in the nasal passage, providing relief from congestion and decreasing excess mucus production. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Cetirizine helps to relieve allergy symptoms. Thus, Coldles Plus Oral Suspension helps to provide relief from symptoms of the common cold and allergies such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

How Coldles Plus Oral Suspension Works

Coldles Plus Oral Suspension is a combination of three drugs, namely, Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Cetirizine (antihistamine/antiallergic). Phenylephrine works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Cetirizine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to relieve symptoms of allergy.

Storage

• Store in a cool and dry place away from sunlight.• Keep Coldles Plus Oral Suspension out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Coldles Plus Oral Suspension
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Get urgent medical help if you notice abnormal lung sounds with symptoms, like bluish skin, flare-ups of your nostrils, or trouble breathing.
  • If you have asthma or allergies, managing these conditions with inhalers and bronchodilators can help prevent abnormal lung sounds.
  • Infections may need antibiotics or breathing therapy to help open your airways and make breathing easier.
  • Wash your hands regularly and take other steps to avoid getting sick and spreading germs.
  • Doing breathing exercises can help improve your lung function and make breathing easier.
  • Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
  • Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
  • Omega-3 supplements may support the transport of oxygen to tissues.
  • Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
  • Quit smoking, as it can worsen hypoxia.
  • Increase vitamin C intake with foods like citrus fruits, berries, broccoli, and bell peppers.
  • Eat antioxidant-rich foods like fruits, vegetables, and whole grains.
  • Stay hydrated by drinking warm liquids like water or herbal tea.
  • Use a humidifier to add moisture to the air.
  • Manage air quality with air purifiers with HEPA filters.
  • Avoid irritants like cigarette smoke, dust, and other airborne irritants.
  • Practice stress management with relaxation techniques like deep breathing exercises.
  • Maintain a clean environment to reduce exposure to dust mites and allergens.
  • Consult a doctor if symptoms persist or are accompanied by other respiratory issues.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

Drug Warnings

If your child is allergic to Phenylephrine, Paracetamol, Cetirizine or any other medicines, please tell your doctor. Please do not give more than the prescribed dose of Coldles Plus Oral Suspension to your child as taking more than a daily dose of Paracetamol may cause serious liver damage or allergic reactions such as swelling of the face, mouth, and throat, difficulty in breathing, itching or rash. If your child is suffering from any medical condition or is under any specific medication, please inform your doctor before using this medicine.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Coldles Plus Oral Suspension:
Taking Tranylcypromine with Coldles Plus Oral Suspension can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Coldles Plus Oral Suspension is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coldles Plus Oral Suspension:
Co-administration of Coldles Plus Oral Suspension with Sevoflurane can increase the levels of Coldles Plus Oral Suspension and lead to side effects.

How to manage the interaction:
Taking Coldles Plus Oral Suspension with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Coldles Plus Oral Suspension:
Co-administration of Selegiline with Coldles Plus Oral Suspension together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Coldles Plus Oral Suspension is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coldles Plus Oral Suspension:
Taking Coldles Plus Oral Suspension with Propofol may lead to increased levels of Coldles Plus Oral Suspension leading to side effects like high blood pressure.

How to manage the interaction:
Taking Coldles Plus Oral Suspension with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Coldles Plus Oral Suspension:
Taking Furazolidone with Coldles Plus Oral Suspension can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Coldles Plus Oral Suspension is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Coldles Plus Oral Suspension only after 14 days of stopping Furazolidone.
How does the drug interact with Coldles Plus Oral Suspension:
Co-administration of Coldles Plus Oral Suspension and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Coldles Plus Oral Suspension and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Coldles Plus Oral Suspension:
Co-administration of Mipomersen with Coldles Plus Oral Suspension may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Coldles Plus Oral Suspension and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Coldles Plus Oral Suspension:
Co-administration of Coldles Plus Oral Suspension may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Coldles Plus Oral Suspension, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coldles Plus Oral Suspension:
Co-administration of Coldles Plus Oral Suspension and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Coldles Plus Oral Suspension and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Coldles Plus Oral Suspension:
Co-administration of Teriflunomide with Coldles Plus Oral Suspension may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Coldles Plus Oral Suspension with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your child’s hands with soap and water regularly to prevent the spread of germs.
  • Provide plenty of foods rich in good bacteria, like yoghurt, to improve overall health.
  • Make sure your child drinks plenty of fluids to avoid dehydration.
  • Make your child gargle with salt water for relief from sore throat.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Consult your doctor

If your child has a history of liver diseases/conditions, please inform your doctor.

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Kidney

Consult your doctor

If your child has a history of kidney diseases/conditions, please inform your doctor.

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Children

Safe if prescribed

Use Coldles Plus Oral Suspension for children as advised by the doctor.

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Heart

Coldles Plus Oral Suspension should be used with caution in children with heart problems, as Phenylephrine may worsen certain cardiac conditions like hypertension or arrhythmias. Always consult a pediatrician before giving this medicine to ensure it's safe for your child's heart health.

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Geriatrics

Not applicable

Coldles Plus Oral Suspension is specifically for children use and is not meant for geriatric patients.

Have a query?

FAQs

Coldles Plus Oral Suspension is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes.

Coldles Plus Oral Suspension contains Phenylephrine, Paracetamol, and Cetirizine. Phenylephrine works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Cetirizine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to relieve symptoms of allergy.

Coldles Plus Oral Suspension also helps to relieve pain and fever. It contains Paracetamol, which acts as a mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever.

You are not recommended to stop giving Coldles Plus Oral Suspension to your child without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, use Coldles Plus Oral Suspension for as long as your doctor has prescribed it, and if your child experiences any difficulty while taking Coldles Plus Oral Suspension, please consult your doctor.

Country of origin

India
Other Info - COLD503

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