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  3. Colgin Plus Tablet 10's

Colgin Plus Tablet 10's, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Colgin Plus Tablet is used to treat the common cold and allergic symptoms like sneezing, watery eyes, or itchy/watery nose and throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps in shrinking the blood vessels in the nasal passage, thereby reducing the stuffy nose. Also, it inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Some people may experience drowsiness, sleepiness, nausea, fatigue, difficulty in sleeping, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CAFFEINE-30MG + CHLORPHENIRAMINE-2MG + PARACETAMOL-500MG + PHENYLEPHRINE-10MG

Manufacturer/Marketer :

Medopharm Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Colgin Plus Tablet

Colgin Plus Tablet is used to treat the common cold and allergic symptoms like sneezing, watery eyes, or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, caused mainly by viruses known as 'rhinovirus.' The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a person who is sick sneezes, coughs, or talks.

Colgin Plus Tablet contains Chlorpheniramine (an antihistamine), Phenylephrine (a decongestant), Paracetamol (a mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that work by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing the stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins', responsible for pain and fever. Caffeine acts as a common stimulant, decreasing sleepiness caused by Chlorpheniramine and speeding up the action of all medicines in Colgin Plus Tablet .

Your doctor will recommend how often you take Colgin Plus Tablet based on your medical condition. Some people may experience drowsiness, sleepiness, nausea, fatigue, difficulty sleeping, and headaches. Most of these side effects may not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Colgin Plus Tablet . If you have high blood pressure (hypertension),  liver or kidney disease, or coronary artery disease (heart disease), avoid using Colgin Plus Tablet as it may worsen your existing condition and symptoms. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness.

Uses of Colgin Plus Tablet

Colgin Plus Tablet is used in the treatment of the common cold and allergies. The detailed uses of Colgin Plus Tablet are as follows:

  • Common Cold: Colgin Plus Tablet helps relieve symptoms like blocked nose, sneezing, runny nose, and watery eyes and reduces nasal congestion and improves breathing.
  • Sinusitis: Colgin Plus Tablet alleviates sinus pain and pressure caused by inflammation, helps clear mucus buildup in the sinuses.
  • Allergic Rhinitis (Hay Fever): Colgin Plus Tablet treats seasonal allergies triggered by pollen, dust, or pet dander and reduces itchy nose, throat irritation, and sneezing.
  • Upper Respiratory Tract Infections: Colgin Plus Tablet provides relief from cough, sore throat, and chest congestion, helps manage mild fever and headaches associated with infections.
  • Nasal Congestion Due to Allergies: Colgin Plus Tablet shrinks swollen blood vessels in the nasal passages to improve airflow and eases breathing difficulties caused by allergic reactions.

Directions for Use

• Colgin Plus Tablet can be taken with or without food, as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication. • Swallow Colgin Plus Tablet as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

Colgin Plus Tablet is primarily used to treat common cold symptoms and allergic symptoms like sneezing, watery eyes, or itchy/watery nose and throat. It is composed of four medicines: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all the medicines present in Colgin Plus Tablet . 

How Colgin Plus Tablet Works

Colgin Plus Tablet is composed of Chlorpheniramine (an antihistamine), Phenylephrine (a decongestant), Paracetamol (a mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that work by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink the blood vessels in the nasal passage, thereby reducing the stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins', responsible for pain and fever. Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all medicines in Colgin Plus Tablet .

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Colgin Plus Tablet

Do not take more than the prescribed dose of Colgin Plus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Please tell your doctor if you are allergic to Colgin Plus Tablet or any other medicines. If you are pregnant, it is advised to inform your doctor before using Colgin Plus Tablet . Do not use Colgin Plus Tablet in breastfeeding mothers without a doctor’s advice, as it contains caffeine, which may be excreted in breast milk and cause harm to the baby. Colgin Plus Tablet is not recommended for children below 4 years. Please do not take more than the prescribed dose of Colgin Plus Tablet as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, enlarged prostate gland,  kidney, liver, heart, or urinary problems, inform your doctor before taking Colgin Plus Tablet . Do not take Colgin Plus Tablet if you have taken an MAO inhibitor (antidepressant medication) in the past 14 days. Also, avoid the intake of chocolate, alcohol, and caffeine-containing beverages like coffee, as they may increase the severity of side effects. Do not take Colgin Plus Tablet if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Cetirizine present in the Colgin Plus Tablet can make you sleepy, so do not drive or operate heavy machinery after taking Colgin Plus Tablet . Phenylephrine in Colgin Plus Tablet should be used cautiously in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). 

Drug-Drug Interactions

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CaffeineIsocarboxazid
Critical
CaffeineLinezolid
Critical

Drug-Drug Interactions

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CaffeineIsocarboxazid
Critical
How does the drug interact with Colgin Plus Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Colgin Plus Tablet with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineLinezolid
Critical
How does the drug interact with Colgin Plus Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Colgin Plus Tablet with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeinePhenelzine
Critical
How does the drug interact with Colgin Plus Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Colgin Plus Tablet with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
CaffeineTranylcypromine
Critical
How does the drug interact with Colgin Plus Tablet:
Coadministration of tranylcypromine with Colgin Plus Tablet can in cause severe high blood pressure.

How to manage the interaction:
Taking Colgin Plus Tablet with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Colgin Plus Tablet:
Taking Colgin Plus Tablet and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Colgin Plus Tablet with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Colgin Plus Tablet:
Taking Colgin Plus Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Colgin Plus Tablet with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
PhenylephrinePropofol
Critical
How does the drug interact with Colgin Plus Tablet:
Taking Colgin Plus Tablet with Propofol may lead to increased levels of Colgin Plus Tablet leading to side effects like high blood pressure.

How to manage the interaction:
Taking Colgin Plus Tablet with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Colgin Plus Tablet:
Co-administration of Selegiline with Colgin Plus Tablet together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Colgin Plus Tablet is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Colgin Plus Tablet:
Taking Furazolidone with Colgin Plus Tablet can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Colgin Plus Tablet is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Colgin Plus Tablet only after 14 days of stopping Furazolidone.
PhenylephrineSevoflurane
Critical
How does the drug interact with Colgin Plus Tablet:
Co-administration of Colgin Plus Tablet with Sevoflurane can increase the levels of Colgin Plus Tablet and lead to side effects.

How to manage the interaction:
Taking Colgin Plus Tablet with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria like yogurt to improve overall health.
  • Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Colgin Plus Tablet as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Colgin Plus Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Colgin Plus Tablet to avoid excessive drowsiness and sleepiness.

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Pregnancy

Caution

The safety of Colgin Plus Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Colgin Plus Tablet is known to pass through milk in small amounts. Use in breastfeeding women is not recommended as it may cause unpleasant side effects to the baby like unusual irritability, excitement.

bannner image

Driving

Unsafe

Colgin Plus Tablet is known to cause drowsiness, so please do not drive or operate any machinery which requires concentration.

bannner image

Liver

Caution

Take Colgin Plus Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Colgin Plus Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

Colgin Plus Tablet is not recommended for children below 4 years. However, it can be given to the children more than 4 years of age only if the doctor has prescribed it.

Have a query?

FAQs

Colgin Plus Tablet is used to treat the common cold and allergy symptoms like sneezing, watery eyes, or itchy/watery nose and throat.Â

Colgin Plus Tablet is composed of four medicines, namely: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.  Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all the medicines present in Colgin Plus Tablet .

Do not use Colgin Plus Tablet if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Colgin Plus Tablet if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Colgin Plus Tablet may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness, or rash, immediately contact your doctor and stop taking Colgin Plus Tablet .

Colgin Plus Tablet contains caffeine. So, avoid taking medicines or food containing caffeine like cold drinks, coffee, chocolate, and tea. Also, avoid consumption of alcohol while taking Colgin Plus Tablet as it might increase drowsiness.

You are not recommended to stop taking Colgin Plus Tablet without consulting your doctor as it may worsen the cough or cause recurring cough. Therefore, take Colgin Plus Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Colgin Plus Tablet , please consult your doctor.

No, it is not advisable to breastfeed while using Colgin Plus Tablet as it contains an antihistamine drug Chlorpheniramine, and also it contains caffeine, which can pass through the breast milk and may harm the baby.

Colgin Plus Tablet is a combination medication containing four active ingredients: Chlorpheniramine (antihistamine), Phenylephrine (decongestant), Paracetamol (mild pain reliever and fever reducer), and Caffeine (stimulant). It treats common cold and allergic symptoms such as sneezing, runny nose, and itchy throat.

Store Colgin Plus Tablet in by keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, place it in a plastic bag and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.

In rare cases, some side effects may become serious, such as severe headaches, allergic reactions, fatigue, severe stomach problems, vomiting, difficulty sleeping, liver problems, and kidney issues. If you experience any of these symptoms, seek medical attention immediately.

No, taking a higher than the recommended dose of Colgin Plus Tablet will not be more effective and may increase the risk of side effects.

Yes, some contraindications are associated with using Colgin Plus Tablet ; it should be used cautiously in certain situations. People who are allergic to any of its ingredients should inform their doctor. It should be used with caution in pregnancy, breastfeeding women, and in children under 4 years. Additionally, individuals with certain medical conditions, such as high blood pressure, diabetes, hyperthyroidism, asthma, and kidney or liver problems, should inform their doctor before taking this medication.

The common side effects of Colgin Plus Tablet are drowsiness, sleepiness, nausea, fatigue, allergic reactions, difficulty sleeping, and headache. Most of these side effects may not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Plot No- 83/A, Phase II, GIDC, Vatva, Ahmedabad - 382445, Gujarat , India
Other Info - COL0531

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 12:08 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2887.pdf
  2. https://www.medicines.org.uk/emc/files/pil.8283.pdf
  3. https://www.drugs.com/cdi/acetaminophen-caffeine-and-phenylephrine.html
  4. https://www.drugs.com/paracetamol.html

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