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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
COLONA-PLUS TABLETS belongs to the class of benzodiazepines. It is used in the treatment of anxiety disorder. This medication contains clonazepam and escitalopram which relieves anxiety by raising the gamma-aminobutyric acid (GABA), a calming chemical mediator. It also helps relax the tense muscles. Common side effects include nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, etc
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Whats That

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Manufacturer/Marketer :

Carron Biotech

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About COLONA-PLUS TABLETS

COLONA-PLUS TABLETS belongs to a group of medications called ‘antianxiety medications' used in the treatment of anxiety disorders. Anxiety is a mental health disorder characterized by feelings of intense, excessive and persistent worry or fear that are strong enough to interfere with one’s daily activities. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

COLONA-PLUS TABLETS is a combination of two drugs: clonazepam and escitalopram oxalate. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram oxalate increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Take COLONA-PLUS TABLETS as prescribed by the doctor. Sometimes, COLONA-PLUS TABLETS may cause common side effects such as nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory problems. Consult your doctor if any of these side effects persist or worsen.

Do not take COLONA-PLUS TABLETS if you are allergic to any of its components. Inform your doctor if you have seizures, liver problems, sleep disorders, lung problems, and alcohol or drug abuse. Do not consume alcohol as it can increase the risk of side effects. Consult your doctor if you are pregnant or breastfeeding before taking this medicine. COLONA-PLUS TABLETS may cause dizziness and drowsiness, so avoid driving vehicles or operating machinery unless you are alert.

Uses of COLONA-PLUS TABLETS

Treatment of Anxiety disorder

Directions for Use

• COLONA-PLUS TABLETS can be taken with or without food.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow the COLONA-PLUS TABLETS as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

COLONA-PLUS TABLETS is a combination of two medicines: clonazepam and escitalopram oxalate. It is used to treat anxiety disorders. Clonazepam increases the effect of gamma-aminobutyric acid (GABA) and produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram oxalate is a selective serotonin reuptake inhibitor (SSRI); it increases the serotonin levels in the brain, thereby improving mood and behaviour.

How COLONA-PLUS TABLETS Works

COLONA-PLUS TABLETS is a combination of two drugs: clonazepam and escitalopram oxalate. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram oxalate increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Storage

• Store in a cool and dry place away from sunlight.
• Keep COLONA-PLUS TABLETS out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of COLONA-PLUS TABLETS

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, dizziness, agitation, tremors, low blood pressure, fast/irregular heart rate, and fluid/electrolyte imbalance. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take COLONA-PLUS TABLETS if you are allergic to any of the ingredients. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or antibiotics. Talk to your doctor if you have a history of seizures, bipolar disorder, or schizophrenia. Patients with liver diseases, diabetes, heart disease, and bleeding disorders should use COLONA-PLUS TABLETS with caution. Please do not stop taking COLONA-PLUS TABLETS abruptly as it can cause withdrawal symptoms. COLONA-PLUS TABLETS may cause suicidal thoughts and worsen anxiety.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamHydrocodone
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Colona-plus Tablets:
Taking Colona-plus Tablets with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Colona-plus Tablets and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamHydrocodone
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Colona-plus Tablets with Hydrocodone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Colona-plus Tablets with Hydrocodone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Colona-plus Tablets:
Co-administration of Tapentadol together with Colona-plus Tablets can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Colona-plus Tablets with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
ClonazepamCodeine
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Colona-plus Tablets with Codeine may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult a doctor if you are taking Colona-plus Tablets with Codeine. Until you know how the medicines affect you, avoid driving or operating hazardous machinery as these medications may cause drowsiness, dizziness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Colona-plus Tablets:
Co-administration of Nalbuphine with Colona-plus Tablets can make the side effects worse.

How to manage the interaction:
Although there is a possible interaction between Colona-plus Tablets and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamMethadone
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Colona-plus Tablets with methadone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Colona-plus Tablets with methadone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Colona-plus Tablets:
Co-administration of Pentazocine with Colona-plus Tablets can increase the risk of side effects.

How to manage the interaction:
Taking Colona-plus Tablets with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Colona-plus Tablets:
Using Morphine together with Colona-plus Tablets can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Colona-plus Tablets can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ClonazepamAlfentanil
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Alfentanil with Colona-plus Tablets can increase the risk of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Colona-plus Tablets and Alfentanil, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamPethidine
Severe
How does the drug interact with Colona-plus Tablets:
Combining Meperidine with Colona-plus Tablets can increase the risk of side effects.

How to manage the interaction:
Taking Pethidine with Colona-plus Tablets together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Attend therapy sessions regularly.
  • Eat a healthy diet.
  • Try to stay active and exercise regularly.
  • Take ample rest. Get enough sleep.
  • Meditate regularly as it helps in easing anxiety.
  • Avoid smoking, caffeine, and alcohol consumption.
  • Foods and drinks like salmon, chamomile, turmeric, dark chocolate, green tea, and yoghurt may help with anxiety.

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS
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Alcohol

Unsafe

Do not consume alcohol while on treatment with COLONA-PLUS TABLETS as it can increase the risk of side effects such as dizziness and drowsiness.

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Pregnancy

Unsafe

COLONA-PLUS TABLETS may show toxic effects on the fetus. So, it is not recommended for use in women who are pregnant or planning pregnancy. Consult your doctor for further advice.

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Breast Feeding

Caution

COLONA-PLUS TABLETS should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.

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Driving

Unsafe

Do not drive vehicles or operate heavy machinery as COLONA-PLUS TABLETS may cause drowsiness.

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Liver

Caution

COLONA-PLUS TABLETS should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.

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Kidney

Caution

COLONA-PLUS TABLETS should be used with caution in patients with kidney failure. Please consult your doctor if you have kidney problems.

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Children

Caution

COLONA-PLUS TABLETS is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

COLONA-PLUS TABLETS belongs to a group of medications called ‘antianxiety medications' used in the treatment of anxiety disorders.

COLONA-PLUS TABLETS works by decreasing the activity in the brain and producing a calming effect. It improves mood, behaviour and cognition in patients with anxiety.

Long-term use of COLONA-PLUS TABLETS may cause suicidal thoughts in some cases. So, use the COLONA-PLUS TABLETS for the duration only as prescribed by your doctor. Consult your doctor immediately if you notice any behavioural changes during the use of COLONA-PLUS TABLETS .

Anxiety is a feeling of fear, worry, or uneasiness. Symptoms include irritability, lack of concentration, fatigue, trembling, and rapid heartbeat. If you experience repeated episodes of anxiety, consult a doctor immediately.

COLONA-PLUS TABLETS may cause a decrease in sexual desire (libido) in men and women. Men can also experience erectile dysfunction. Consult your doctor if you experience any change in sexual desire after taking COLONA-PLUS TABLETS .

COLONA-PLUS TABLETS may cause hair loss in rare cases. If you experience excessive hair loss, please consult your doctor.

COLONA-PLUS TABLETS may take a few weeks to show its effectiveness. To get its full benefits, take COLONA-PLUS TABLETS for as long as the doctor has prescribed it.

COLONA-PLUS TABLETS should be used for the duration prescribed by the doctor based on your health condition. Avoid using COLONA-PLUS TABLETS for longer durations unless advised by the doctor as it might cause suicidal thoughts in some cases.

COLONA-PLUS TABLETS may not interfere with contraceptives. However, consult the doctor if you are concerned about contraceptive effectiveness while taking COLONA-PLUS TABLETS .

COLONA-PLUS TABLETS is a combination medication consisting of clonazepam and escitalopram oxalate used for the treatment of anxiety disorders. Clonazepam works by enhancing the effects of gamma-aminobutyric acid (GABA), which helps in calming the brain by reducing excessive nerve activity. Escitalopram oxalate is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in the brain and helps to improve mood and behaviour.

Yes, COLONA-PLUS TABLETS may cause sleepiness or drowsiness. If you experience these symptoms avoid driving or operating machinery.

No, you should not take higher than the recommended dose of COLONA-PLUS TABLETS as it might cause unpleasant side effects. Always follow the dose as prescribed by the doctor based on your health condition to reduce the side effects.

COLONA-PLUS TABLETS should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

No, you should not stop taking COLONA-PLUS TABLETS even though your symptoms are relieved as it may cause withdrawal symptoms like suicidal thoughts and may worsen anxiety. Consult the doctor before discontinuing the medicine.

The side effects of COLONA-PLUS TABLETS include headache, confusion, drowsiness, nausea, stomach upset, dizziness, breathlessness, fatigue, sleeping problems, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory issues. Talk to the doctor if the side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

NEAR SHIV MANDIR, 32/1, NABAPALLY CIRCULAR ROAD, NABAPALLY, BARASAT, Nobopurli Barasat, Kolkata-700126, West Bengal, India
Other Info - COL1192

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