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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Comantrel 100 mg Tablet 10's is used to treat Parkinson's disease symptoms. It plays a vital role in treating symptoms such as difficulty moving, muscle stiffness, and tremors. It contains Amantadine, which increases dopamine (a chemical) levels in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions more efficiently and improves the quality of life. In some cases, it may cause side effects like dry mouth, constipation, balance disorder (loss of balance), blurred vision, insomnia (difficulty sleeping), and peripheral oedema. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

AMANTADINE HYDROCHLORIDE

Composition :

AMANTADINE-100MG

Manufacturer/Marketer :

Consern Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Comantrel 100 mg Tablet 10's

Comantrel 100 mg Tablet 10's is used to treat Parkinson's disease symptoms. It plays a vital role in treating symptoms such as difficulty moving, muscle stiffness, and tremors. Parkinson's disease is a nervous system disorder that causes movement, muscle control, balance, and other similar conditions.

Comantrel 100 mg Tablet 10's contains amantadine, which works by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions more efficiently and improves the quality of life.

In some cases, Comantrel 100 mg Tablet 10's may cause side effects like dry mouth, constipation, balance disorder (loss of balance), blurred vision, insomnia (difficulty sleeping), and peripheral oedema. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Comantrel 100 mg Tablet 10's if you are allergic to any of its components, have severe liver or kidney problems, or have epilepsy. Check with your doctor if you're pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines. Also, do not stop Comantrel 100 mg Tablet 10's abruptly, as it may lead to severe side effects. Consult your doctor, and he/she might lower the dose gradually.

Uses of Comantrel 100 mg Tablet 10's

Comantrel 100 mg Tablet 10's used in the treatment of Parkinson's disease. The detailed uses of Comantrel 100 mg Tablet 10's are as follows:

  • Treatment of Parkinson's Disease: Comantrel 100 mg Tablet 10's treats symptoms of Parkinson's disease, such as movement difficulties, muscle control issues, and balance problems. It also treats 'off' episodes in people with Parkinson's disease.
  • Treatment and Prevention of Influenza A: Comantrel 100 mg Tablet 10's prevents and treats influenza A virus infections, including respiratory infections caused by the virus, by stopping the spread of the virus in the body.
  • Treatment of Drug-Induced Movement Problems: Comantrel 100 mg Tablet 10's is used to treat drug-induced extrapyramidal reactions, helping to alleviate movement-related symptoms.

Directions for Use

  • Take Comantrel 100 mg Tablet 10's with or without food as advised by your doctor.
  • It is advised to take Comantrel 100 mg Tablet 10's once a day at bedtime; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Comantrel 100 mg Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Comantrel 100 mg Tablet 10's contains amantadine (dopamine agonist), which is an anti-Parkinson's drug.
  • It helps treat Parkinson's disease by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination.
  • Thus, it effectively helps in performing daily functions in a better way and improving quality of life.

How Comantrel 100 mg Tablet 10's Works

Comantrel 100 mg Tablet 10's contains amantadine (dopamine agonist), which is an anti-Parkinson's drug. It helps treat Parkinson's disease by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions in a better way and improving quality of life.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Comantrel 100 mg Tablet 10's

Do not take more than the prescribed dose of Comantrel 100 mg Tablet 10's as it may cause overdose. The symptoms of overdose include difficulty breathing, decreased urination, irregular or fast heartbeat, confusion, problems with coordination, stiff or rigid arms/legs, hallucinations and fear/irritability/aggressive behaviour. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Comantrel 100 mg Tablet 10's if you are allergic to amantadine or any of its ingredients.
  • Inform your doctor about all other OTC medications, vitamins, nutritional supplements, and herbal products you are taking or are planning to take.
  • If you have kidney or liver disease, mental illness, glaucoma, epilepsy, a sleep disorder, eczema, urinary tract infections, heart failure, hypotension (low blood pressure), or if you drink or have ever consumed large amounts of alcohol, Comantrel 100 mg Tablet 10's should be taken with caution and only if a doctor prescribes it to you.
  • Tell your doctor if you are pregnant or breastfeeding before starting Comantrel 100 mg Tablet 10's, as a dose adjustment may be required if the benefits outweigh the risks.
  • Comantrel 100 mg Tablet 10's may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking Comantrel 100 mg Tablet 10's so please get up gradually.
  • Also, do not take any live vaccination for at least 48 hours after the last dose of Comantrel 100 mg Tablet 10's.
  • Avoid dairy products as it may cause disease progression, and take some calcium supplements to avoid their deficiency.

Diet & Lifestyle Advise

  • Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.
  • Include turmeric or yellow mustard in your diet to avoid constipation caused by Parkinson’s disease, and increase the intake of fluids to stay hydrated.
  • Caffeine can help slow down the progression of the disease.
  • Take enough vitamin D and fresh air, as they are known to improve the symptoms of Comantrel 100 mg Tablet 10's.

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS
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Alcohol

Unsafe

Intake of alcohol with Comantrel 100 mg Tablet 10's may damage your liver. Therefore, you are recommended to avoid consumption of alcohol with Comantrel 100 mg Tablet 10's.

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Pregnancy

Consult your doctor

Comantrel 100 mg Tablet 10's is a pregnancy Category C medicine. It is not known whether Comantrel 100 mg Tablet 10's will affect pregnant women or fetus. Therefore, Comantrel 100 mg Tablet 10's is given to pregnant women only if doctor thinks benefits are greater than risks.

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Breast Feeding

Unsafe

Comantrel 100 mg Tablet 10's is excreted in human milk. But the amount of Comantrel 100 mg Tablet 10's absorbed by the nursing infant is unknown. So, it should not be taken while breastfeeding.

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Driving

Unsafe

Comantrel 100 mg Tablet 10's can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Unsafe

Comantrel 100 mg Tablet 10's is unsafe, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-colored urine, or yellowing of skin/eye.

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Kidney

Caution

Comantrel 100 mg Tablet 10's to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Comantrel 100 mg Tablet 10's can be given to children but under medical supervision. Comantrel 100 mg Tablet 10's is prescribed to the children to treat complicated urinary tract infections, anthrax infection, or plague infection.

Have a query?

FAQs

Comantrel 100 mg Tablet 10's is used to treat Parkinson's disease symptoms. It plays a vital role in treating symptoms such as difficulty moving, muscle stiffness, and tremors.

Comantrel 100 mg Tablet 10's works by increasing dopamine (a chemical) level in the brain, responsible for improving body movement coordination. Thus, it effectively helps in performing daily functions in a better way and improving quality of life.

No, Comantrel 100 mg Tablet 10's should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

If you miss a dose of Comantrel 100 mg Tablet 10's, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

No, Comantrel 100 mg Tablet 10's should not be taken if you have epilepsy as it might increase your chances of seizures. Please consults your doctor before starting Comantrel 100 mg Tablet 10's.

You should inform your doctor, and he might stop the use of Comantrel 100 mg Tablet 10's before the surgery.

Do not stop taking Comantrel 100 mg Tablet 10's without talking to your doctor. If you suddenly stop taking Comantrel 100 mg Tablet 10's, you may experience confusion, fever, mental state changes, or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.

Amantadine is a dopamine agonist used to treat Parkinson's disease and its symptoms, including dyskinesia (sudden uncontrolled movements).

Amantadine may cause constipation as a common side effect. Usually, it is temporary, does not require medical attention, and gradually resolves over time. However, if this persistent, reach out to your doctor.

Yes, in some cases, Comantrel 100 mg Tablet 10's has been used for neuropathic pain.

Comantrel 100 mg Tablet 10's contains Amantadine as an active ingredient.

Comantrel 100 mg Tablet 10's may cause some people to become dizzy, drowsy, or lightheaded, leading to tiredness or fatigue.

If you suddenly stop taking Comantrel 100 mg Tablet 10's, you may experience confusion, fever, mental state changes, or severe muscle stiffness. Depending on your disease condition, your doctor will decrease your dose gradually, if necessary.

Comantrel 100 mg Tablet 10's is not a dopamine agonist. It may inhibit the reuptake of dopamine and increase the synthesis and release of dopamine.

Individual needs may vary from person to person, so it should be used as directed by the physician.

Yes, Comantrel 100 mg Tablet 10's can be taken with or without food.

In rare cases, Comantrel 100 mg Tablet 10's may cause anxiety and feeling overexcited. If you experience any of these symptoms or if they persist, please consult the doctor.

Overdose symptoms may include confusion, agitation, behaviour changes, hallucinations, severe headache or pounding in your ears, muscle stiffness, problems with balance or walking, trouble breathing, Tachycardia (fast heartbeats) and seizures.

Limited research is available. Consult your doctor if you have any questions or concerns regarding this.

With continued Comantrel 100 mg Tablet 10's use, decreased weight and body mass index may occur. Seek medical attention if you observe any significant or sudden changes.

Comantrel 100 mg Tablet 10's may cause side effects like dry mouth, constipation, balance disorder (loss of balance), blurred vision, insomnia (difficulty sleeping), and peripheral oedema. Most of these side effects of Comantrel 100 mg Tablet 10's are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects persist, contact your doctor.

Country of origin

India

Manufacturer/Marketer address

Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India.
Other Info - COM0907

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