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compositionComposition:DULOXETINE-30MG
prescription
Prescription Medicine
info
Contipress 30 mg Tablet 10's
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DULOXETINE-30MG

Manufacturer/Marketer :

A N Pharmacia Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Contipress-30mg Tablet

DULOXETINE is an oral prescription medication primarily used to treat major depressive disorder and generalised anxiety disorder. It is also clinically approved to manage chronic pain conditions, such as diabetic nerve pain, fibromyalgia, and persistent joint or muscle pain. By balancing key chemical messengers in the brain and nervous system, this medicine helps improve both your emotional state and physical pain symptoms.

This medication is typically taken once or twice daily, and taking it consistently at the same time every day is essential to keep a steady level of medicine in your body. You can take this medicine with or without food, but taking it with a meal can help reduce initial nausea. Making gradual diet and lifestyle changes, such as incorporating gentle daily movement, eating balanced meals, and practising stress-reduction techniques, can significantly support your treatment results.

While many people tolerate this medication well, common side effects can include dry mouth, mild nausea, sleepiness, and increased sweating. You must consult your doctor immediately if you experience serious side effects, such as severe dizziness, yellowing of your skin or eyes, dark urine, or unusual changes in your mood.

Talk to your doctor before starting this medicine if you have a history of high blood pressure, seizures, liver problems, or kidney issues. Do not take this if you have uncontrolled narrow-angle glaucoma or severe kidney disease, as this medication can worsen these conditions.

This medicine can interact with alcohol, smoking, and other prescription drugs, potentially causing severe liver damage or a dangerous increase in serotonin levels. If you are pregnant, planning to breastfeed, or are an elderly individual, consult your doctor to ensure this treatment is safe and appropriate for your specific health needs.

Uses of Contipress-30mg Tablet

DULOXETINE is used to treat major depressive disorder and generalised anxiety disorder. The detailed uses of DULOXETINE are as follows:

  • Major Depressive Disorder: DULOXETINE helps relieve persistent feelings of sadness, low energy, and loss of interest in activities by balancing chemical messengers in the brain.
  • Generalised Anxiety Disorder: It reduces constant, excessive, and daily worry, as well as the physical symptoms of tension that accompany anxiety.
  • Diabetic Peripheral Neuropathic Pain: It dulls the burning, stabbing, or shooting nerve pain in the feet and hands caused by nerve damage in diabetic patients.
  • Fibromyalgia: It helps manage and reduce widespread muscle pain, joint stiffness, and deep fatigue throughout the body.
  • Chronic Musculoskeletal Pain: It provides daily relief for ongoing physical discomfort, such as chronic lower back pain and osteoarthritis pain.
     

Key Benefits

DULOXETINE helps manage certain mental health conditions and chronic pain disorders by affecting key chemical messengers in the brain and nervous system. By improving mood, reducing pain signals, and enhancing overall well-being, it can support a better quality of life. This medicine offers several key benefits:

  • Improves Mood and Emotional Balance: By adjusting key brain chemicals, this medicine helps lift persistent sadness, reduces nervous tension, and allows you to participate more fully in daily life.
  • Relieves Difficult Chronic Pain: It acts directly on pain pathways in the central nervous system, providing significant relief from long-standing nerve and joint pain that may not respond well to standard pain relievers.
  • Promotes Better Daily Functioning: Easing both emotional symptoms and physical pain often leads to improved energy levels, better sleep quality, and the ability to move more comfortably throughout the day.
     
Side effects of Contipress 30 mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
  • Avoid smoking and drinking alcohol as it can worsen your condition.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

To get the full benefit of DULOXETINE and minimise side effects, follow these simple guidelines:

  • Swallow the capsule whole with a full glass of water. Do not chew, crush, or open the capsule, as breaking the protective coating can affect how the medicine is absorbed and may increase stomach irritation.
  • You can take this medication with or without food. If you experience stomach upset or nausea when first starting, taking your dose with a light meal can help.
  • Try to take your dose at the same time every day to maintain a steady level of the medicine in your body.
  • Always follow your doctor's exact instructions regarding how and when to take this medicine. Do not alter your dose or stop taking it without discussing it with your healthcare provider first.
     

How Contipress-30mg Tablet Works

DULOXETINE belongs to a class of medications called serotonin-norepinephrine reuptake inhibitors (SNRIs). In your brain and spinal cord, there are natural chemical messengers called serotonin and norepinephrine. Serotonin plays a key role in regulating your mood, sleep, and anxiety, while norepinephrine helps control attention, alertness, and the way your body processes pain signals. Under normal circumstances, nerve cells quickly reabsorb these chemicals after they are released. This medication works by stopping that reabsorption process. By keeping higher levels of serotonin and norepinephrine active in the spaces between nerve cells, it enhances their mood-boosting effects and helps block the transmission of chronic pain signals traveling to the brain.
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Alcohol

Unsafe

Taking Contipress-30mg Tablet with alcohol may increase the side effects, such as confusion, drowsiness, and trouble concentrating. A few people may find it difficult to do mental tasks. Hence, limit the use of alcohol while being treated with this medicine.

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Pregnancy

Caution

Contipress-30mg Tablet is only recommended for use during pregnancy if advised by a doctor. This medicine increases the risk of deformities in infants, so one should tell their doctor if they are pregnant.

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Breast Feeding

Consult your doctor

Let your doctor know if you are a nursing mother before taking Contipress-30mg Tablet ; your doctor will decide whether Contipress-30mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Contipress-30mg Tablet can cause sleepiness or may affect a person's ability to drive so one should avoid driving or doing any work that needs clear attention.

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Liver

Unsafe

Contipress-30mg Tablet is not recommended for use in patients with liver disease. Inform your doctor if you have any preexisting liver disease.

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Kidney

Unsafe

Contipress-30mg Tablet is not recommended for use in patients dealing with severe kidney disease.

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Children

Caution

The usage of Contipress-30mg Tablet is not recommended for children below seven years old. However, this medicine can be used in children above seven years after a doctor's recommendation.

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Heart

Consult your doctor

Contipress-30mg Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Consult your doctor

Contipress-30mg Tablet is safe for use in geriatric patients if recommended by the physician. Your doctor will decide the dose and duration of medicine.

What if I have taken an overdose of Contipress-30mg Tablet

Do not take more than the prescribed dose of Contipress-30mg Tablet as it may cause serious side effects. The symptoms of overdose include vomiting, excess sleepiness, tremors, dizziness, fast heart rate, sweating and restlessness. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Avoid or strictly limit alcohol: Drinking alcohol while taking this medicine significantly increases the risk of severe liver damage and can make drowsiness or dizziness much worse.
  • Stand up slowly: This medication can cause a sudden, temporary drop in blood pressure when you stand up. Rise slowly from a sitting or lying position to prevent feeling lightheaded or falling.
  • Stay well hydrated: Drink plenty of water throughout the day to help manage dry mouth and reduce the likelihood of constipation.
  • Engage in low-impact physical activity: Gentle exercises like walking, swimming, or stretching can help reduce chronic joint or nerve pain and naturally support your mental health.
     

Have a query?

How Soon It Starts Working

  • The time required for Contipress-30mg Tablet to start to work: Contipress-30mg Tablet ideally shows its action within 6 to 10 hours after administration.
  • The time for which the effects of Contipress-30mg Tablet last: The effect of Contipress-30mg Tablet lasts for 24 hours.

What if you forget to take Contipress-30mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store this medication at room temperature, ideally between 20°C to 25°C (68°F to 77°F). •Keep the capsules in their original container, tightly closed, to protect them from light and moisture.

Drug Warnings

  • Never stop taking this medicine abruptly: Stopping suddenly can cause uncomfortable withdrawal symptoms, such as dizziness, headaches, nausea, and burning or tingling sensations. Always consult your doctor to plan a schedule for gradually decreasing your dose.
  • Monitor your mood closely: Pay close attention to any sudden shifts in your thoughts, feelings, or behaviours, especially when you first start this medicine or when your dose is adjusted. Report any worsening depression or suicidal thoughts to your doctor immediately.
  • Do not drive until you know how this medicine affects you: This medication can cause sleepiness, blurred vision, or dizziness. Avoid driving or operating heavy machinery until you are confident you can do so safely.
  • Keep an eye on your blood pressure: This medicine can raise blood pressure in some individuals. Your doctor may want to monitor your blood pressure regularly during your treatment.
  • Inspect your capsules: Before taking your dose, ensure the capsule is completely intact, dry, and has no visible cracks or leakage.
     

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine with or within 14 days of stopping an MAOI, as this can cause a life-threatening increase in serotonin levels (serotonin syndrome).
  • Other Serotonergic Drugs: Combining this medicine with SSRIs, triptans, or tramadol increases the risk of serotonin syndrome, which causes confusion, rapid heart rate, and muscle stiffness.
  • Blood Thinners: Taking this medicine alongside blood thinners like warfarin, aspirin, or NSAIDs can increase your risk of unusual bleeding or bruising.
  • CYP1A2 or CYP2D6 Inhibitors: Certain medications can slow down how your body processes this drug, leading to higher levels in your system and increased side effects.

Drug-Food Interactions:

  • Alcohol: Avoid alcohol completely, as it significantly raises the risk of severe liver damage and worsens drowsiness.

Drug-Disease Interactions:

  • Liver Disease: This medicine should not be taken if you have chronic liver disease, as it can cause further, severe liver damage.
  • Severe Kidney Disease: Reduced kidney function can cause the medication to build up in your body, increasing your risk of adverse effects.
  • Uncontrolled Glaucoma: This medicine can increase pressure in your eyes and should not be used if you have uncontrolled narrow-angle glaucoma.
     
DuloxetineTranylcypromine
Critical
DuloxetineLinezolid
Critical

Drug-Drug Interactions

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DuloxetineTranylcypromine
Critical
How does the drug interact with Contipress 30 mg Tablet:
Taking Tranylcypromine with Contipress 30 mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Contipress 30 mg Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineLinezolid
Critical
How does the drug interact with Contipress 30 mg Tablet:
Taking Contipress 30 mg Tablet with Linezolid can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Contipress 30 mg Tablet with Linezolid is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
DuloxetineSelegiline
Critical
How does the drug interact with Contipress 30 mg Tablet:
Taking Contipress 30 mg Tablet with selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between Contipress 30 mg Tablet and Selegiline, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineSafinamide
Critical
How does the drug interact with Contipress 30 mg Tablet:
Coadministration of safinamide with Contipress 30 mg Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Safinamide with Contipress 30 mg Tablet is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetinePhenelzine
Critical
How does the drug interact with Contipress 30 mg Tablet:
Taking phenelzine with Contipress 30 mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Contipress 30 mg Tablet with Phenelzine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineMetoclopramide
Critical
How does the drug interact with Contipress 30 mg Tablet:
Coadministration of metoclopramide with Contipress 30 mg Tablet increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metoclopramide with Contipress 30 mg Tablet is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
DuloxetineProcarbazine
Critical
How does the drug interact with Contipress 30 mg Tablet:
Taking Contipress 30 mg Tablet with procarbazine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Contipress 30 mg Tablet with Procarbazine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineEliglustat
Critical
How does the drug interact with Contipress 30 mg Tablet:
Coadministration of eliglustat and Contipress 30 mg Tablet can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Contipress 30 mg Tablet with Eliglustat is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, or weak pulse. Do not discontinue any medications without consulting your doctor.
DuloxetineRasagiline
Critical
How does the drug interact with Contipress 30 mg Tablet:
Taking Rasagiline with Contipress 30 mg Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Rasagiline and Contipress 30 mg Tablet is not recommended as they can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineCiprofloxacin
Severe
How does the drug interact with Contipress 30 mg Tablet:
Taking Contipress 30 mg Tablet with ciprofloxacin may significantly increases the blood levels of Contipress 30 mg Tablet and increase the risk of side effects.

How to manage the interaction:
Although taking ciprofloxacin and Contipress 30 mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach pain, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

Contipress-30mg Tablet is primarily used for the treatment of depression and anxiety. Besides this, it is also used to treat neuropathic pain such as fibromyalgia associated with diabetic peripheral neuropathy and can be used to treat stress urinary incontinence in women.

Contipress-30mg Tablet works by increasing the amount of mood-enhancing chemicals serotonin and noradrenaline in the brain.

No, the person having a liver problem facing us, symptoms like itching, dark urine, right-sided upper stomach pain, and jaundice is not allowed to use this medicine.

Duloxetine has been used safely for a long time. Long-term negative effects are not present.

Report it to your doctor on an urgent basis, as they will either change the dosing strength or change the medicine.

The use of Contipress-30mg Tablet is restricted if a patient has used an MAO inhibitor (Selegiline, etc) within 5 days before or 14 days after, as it may result in serious drug interaction.

There is no evidence to suggest that duloxetine will reduce fertility in either men or women. But speak to your doctor before taking it if you are trying to get pregnant.

Do not stop taking Contipress-30mg Tablet suddenly or reduce the dose on your own, even if you start feeling better. Stopping abruptly may cause withdrawal symptoms such as dizziness, nausea, headache, irritability, sleep disturbances, nightmares, or tingling sensations. If your doctor decides that treatment should be stopped, they will gradually reduce your dose over several weeks or longer to minimize withdrawal effects. Always consult your doctor before making any changes to your treatment.

You may notice improvements in sleep, appetite, or energy levels within 1 to 2 weeks of starting Contipress-30mg Tablet . However, it usually takes 4 to 6 weeks of regular use to experience the full benefits for depression, anxiety, or pain relief. Continue taking the medicine as prescribed and talk to your doctor if you do not notice improvement after several weeks.

Contipress-30mg Tablet is generally not considered addictive. However, prolonged use may lead to physical dependence, which means stopping the medicine suddenly can cause withdrawal symptoms. Always take the medicine exactly as prescribed and do not increase the dose without medical advice.

Using warfarin together with Contipress-30mg Tablet can cause you to bleed more easily.

Contipress-30mg Tablet is safe to take for a long time. There are not any long-term side effects. If you have been feeling better for six months or more, your doctor may suggest coming off duloxetine.

Yes, Contipress-30mg Tablet may increase blood pressure in some people. Your doctor may monitor your blood pressure regularly, especially if you already have hypertension. If you notice a significant rise in blood pressure while taking Contipress-30mg Tablet , contact your doctor for evaluation and advice.

Common side effects of Contipress-30mg Tablet include feeling sick, dry mouth, headache, constipation and feeling sleepy. Most of these side effects of Contipress-30mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Serious adverse effects of duloxetine are uncommon; however, they can include allergic reactions, increased bleeding risk, and mania. If you suffer any major adverse effects, please immediately seek medical attention.

The suggested Contipress-30mg Tablet dosage is determined by your unique needs and the condition being treated. Your doctor can provide personalized advice.

Contipress-30mg Tablet is generally considered safe for most individuals, although it may not be appropriate for everyone. Pregnant women, children, and people with certain medical conditions should consult a doctor before using duloxetine.

It is recommended to avoid alcohol while taking Contipress-30mg Tablet . Alcohol can increase side effects such as drowsiness, dizziness, impaired concentration, and poor coordination. In addition, combining alcohol with duloxetine may increase the risk of liver damage. Consult your doctor if you have questions about alcohol consumption while taking this medicine.

The use of Contipress-30mg Tablet is not allowed in children under seven. However, this medicine can be used in children over seven after a doctor's recommendation.

Yes, you can take this medication with or without food. If you find that it makes you feel nauseous when you first start, taking your dose with a meal or a light snack can help settle your stomach. Talk to your doctor if nausea persists.

Some people may experience a decreased appetite and mild weight loss when they first start taking this medicine. Over long-term use, some individuals may notice modest weight changes. If you have concerns about weight changes, talk to your doctor.

Yes, drowsiness, sleepiness, and fatigue are common side effects of this medication, especially when you first start taking it or when your dose is increased. Avoid driving or operating machinery until you know how the medicine affects you. Talk to your doctor if the sleepiness is severe or does not go away.

Taking this medication during the later stages of pregnancy may carry some risks for the newborn, such as temporary breathing difficulties or withdrawal symptoms. However, untreated depression or chronic pain also poses health risks. Talk to your doctor to weigh the potential risks and benefits for your specific situation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.6868 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. National Health Service (NHS). Duloxetine - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  3. U.S. Food and Drug Administration (FDA). 021427S049Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  4. Drugs.com Clinical Review Team. Duloxetine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  5. Duloxetine hydrochloride. 2004. [Accessed on 23 Jan. 2019] Check here
  6. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 20 Feb. 2020] Check here
  7. Ema.Cymbalta 30 mg hard gastro-resistant capsules. [[Accessed on 12 Sept].2019]Check here

Country of origin

India

Manufacturer/Marketer address

14/1, Salua, Dasdrone Main Road, Rajarhat, Gopalpur, Kolkata 700136
Other Info - CON0527

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